Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis von Muzio, Luca, Sirtori, Riccardo, Gornati, Davide, Eleuteri, Simona, Fossaghi, Andrea, Brancaccio, Diego, Manzoni, Leonardo, Ottoboni, Linda, Feo, Luca De, Quattrini, Angelo, Mastrangelo, Eloise, Sorrentino, Luca, Scalone, Emanuele, Comi, Giancarlo, Marinelli, Luciana, Riva, Nilo, Milani, Mario, Seneci, Pierfausto, Martino, Gianvito

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Targeting the BIR Domains of Inhibitor of Apoptosis (IAP) Proteins in Cancer Treatment von Cossu, Federica, Milani, Mario, Mastrangelo, Eloise, Lecis, Daniele

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Acid-sensing ion channel 3 is a new potential therapeutic target for the control of glioblastoma cancer stem cells growth von Balboni, Andrea, D’Angelo, Camilla, Collura, Nicoletta, Brusco, Simone, Di Berardino, Claudia, Targa, Altea, Massoti, Beatrice, Mastrangelo, Eloise, Milani, Mario, Seneci, Pierfausto, Broccoli, Vania, Muzio, Luca, Galli, Rossella, Menegon, Andrea

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New Class of Benzodiazepinone Derivatives as Pro-Death Agents Targeting BIR Domains in Cancer Cells von Fiore, Michele, Mosconi, Michele, Bonì, Francesco, Parodi, Alice, Salis, Annalisa, Tasso, Bruno, Mastrangelo, Eloise, Millo, Enrico, Cossu, Federica

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Structure-Based Inhibition of Norovirus RNA-Dependent RNA Polymerases von Mastrangelo, Eloise, Pezzullo, Margherita, Tarantino, Delia, Petazzi, Roberto, Germani, Francesca, Kramer, Dorothea, Robel, Ivonne, Rohayem, Jacques, Bolognesi, Martino, Milani, Mario

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Comprehensive response to Usutu virus following first isolation in blood donors in the Friuli Venezia Giulia region of Italy: Development of recombinant NS1-based serology and sens... von Caracciolo, Ilaria, Mora-Cardenas, Erick, Aloise, Chiara, Carletti, Tea, Segat, Ludovica, Burali, Maria Sole, Chiarvesio, Alexsia, Totis, Vivianna, Avšič-Županc, Tatjana, Mastrangelo, Eloise, Manfroni, Giuseppe, D'Agaro, Pierlanfranco, Marcello, Alessandro

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Stabilization of the retromer complex: Analysis of novel binding sites of bis-1,3-phenyl guanylhydrazone 2a to the VPS29/VPS35 interface von Fagnani, Elisa, Bonì, Francesco, Seneci, Pierfausto, Gornati, Davide, Muzio, Luca, Mastrangelo, Eloise, Milani, Mario

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Structure and functionality in flavivirus NS-proteins: Perspectives for drug design von Bollati, Michela, Alvarez, Karin, Assenberg, René, Baronti, Cécile, Canard, Bruno, Cook, Shelley, Coutard, Bruno, Decroly, Etienne, de Lamballerie, Xavier, Gould, Ernest A., Grard, Gilda, Grimes, Jonathan M., Hilgenfeld, Rolf, Jansson, Anna M., Malet, Hélène, Mancini, Erika J., Mastrangelo, Eloise, Mattevi, Andrea, Milani, Mario, Moureau, Grégory, Neyts, Johan, Owens, Raymond J., Ren, Jingshan, Selisko, Barbara, Speroni, Silvia, Steuber, Holger, Stuart, David I., Unge, Torsten, Bolognesi, Martino

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The antipsychotic drug lurasidone inhibits coronaviruses by affecting multiple targets von Baroni, Sara, Carletti, Tea, Donalisio, Manuela, Arduino, Irene, Cazzaniga, Irene, Giorgino, Toni, Esposito, Francesca, Porta, Alessia, Diomede, Luisa, De Luigi, Ada, Gobbi, Marco, Lembo, David, Marcello, Alessandro, Tramontano, Enzo, Milani, Mario, Mastrangelo, Eloise

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Structural bases of norovirus RNA dependent RNA polymerase inhibition by novel suramin-related compounds von Croci, Romina, Pezzullo, Margherita, Tarantino, Delia, Milani, Mario, Tsay, Shwu-Chen, Sureshbabu, Radhakrishnan, Tsai, Yi-Jin, Mastrangelo, Eloise, Rohayem, Jacques, Bolognesi, Martino, Hwu, Jih Ru

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Crystal Structure of a Novel Conformational State of the Flavivirus NS3 Protein: Implications for Polyprotein Processing and Viral Replication von ASSENBERG, René, MASTRANGELO, Eloise, WALTER, Thomas S, VERMA, Anil, MILANI, Mario, OWENS, Raymond J, STUART, David I, GRIMES, Jonathan M, MANCINI, Erika J

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Head or tail? A molecular dynamics approach to the complex structure of TNF-associated factor TRAF2

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Virucidal Activity of the Pyridobenzothiazolone Derivative HeE1-17Y against Enveloped RNA Viruses von Milan Bonotto, Rafaela, Bonì, Francesco, Milani, Mario, Chaves-Sanjuan, Antonio, Franze, Silvia, Selmin, Francesca, Felicetti, Tommaso, Bolognesi, Martino, Konstantinidou, Soultana, Poggianella, Monica, Márquez, Chantal L., Dattola, Federica, Zoppè, Monica, Manfroni, Giuseppe, Mastrangelo, Eloise, Marcello, Alessandro

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Modulation of Guanylate Cyclase Activating Protein 1 (GCAP1) Dimeric Assembly by Ca2+ or Mg2+: Hints to Understand Protein Activity von Bonì, Francesco, Marino, Valerio, Bidoia, Carlo, Mastrangelo, Eloise, Barbiroli, Alberto, Dell’Orco, Daniele, Milani, Mario

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Structure-based identification of a new IAP-targeting compound that induces cancer cell death inducing NF-κB pathway von Cossu, Federica, Camelliti, Simone, Lecis, Daniele, Sorrentino, Luca, Majorini, Maria Teresa, Milani, Mario, Mastrangelo, Eloise

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The structure of N184K amyloidogenic variant of gelsolin highlights the role of the H-bond network for protein stability and aggregation properties von de Rosa, Matteo, Barbiroli, Alberto, Bonì, Francesco, Scalone, Emanuele, Mattioni, Davide, Vanoni, Maria A., Patrone, Marco, Bollati, Michela, Mastrangelo, Eloise, Giorgino, Toni, Milani, Mario

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Discovery of a Novel Class of Norovirus Inhibitors with High Barrier of Resistance von Van Dycke, Jana, Puxeddu, Michela, La Regina, Giuseppe, Mastrangelo, Eloise, Tarantino, Delia, Rymenants, Jasper, Sebastiani, Jessica, Nalli, Marianna, Matthijnssens, Jelle, Neyts, Johan, Silvestri, Romano, Rocha-Pereira, Joana

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Liposomal Systems as Nanocarriers for the Antiviral Agent Ivermectin von Nastruzzi, Claudio, Pezzullo, Margherita, Watanabe, Satoru, Chan, Kitti Wing Ki, Bottaro, Elisabetta, Croci, Romina, Mastrangelo, Eloise

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A novel hotspot of gelsolin instability triggers an alternative mechanism of amyloid aggregation von Bollati, Michela, Diomede, Luisa, Giorgino, Toni, Natale, Carmina, Fagnani, Elisa, Boniardi, Irene, Barbiroli, Alberto, Alemani, Rebecca, Beeg, Marten, Gobbi, Marco, Fakin, Ana, Mastrangelo, Eloise, Milani, Mario, Presciuttini, Gianluca, Gabellieri, Edi, Cioni, Patrizia, de Rosa, Matteo

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Structural insight into inhibitor of apoptosis proteins recognition by a potent divalent smac-mimetic von Cossu, Federica, Milani, Mario, Vachette, Patrice, Malvezzi, Francesca, Grassi, Serena, Lecis, Daniele, Delia, Domenico, Drago, Carmelo, Seneci, Pierfausto, Bolognesi, Martino, Mastrangelo, Eloise

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