Collective synthesis of natural products by means of organocascade catalysis von Jones, Spencer B., Simmons, Bryon, Mastracchio, Anthony, MacMillan, David W. C.

Volltext

Enantioselective Organocatalysis Using SOMO Activation von Beeson, Teresa D, Mastracchio, Anthony, Hong, Jun-Bae, Ashton, Kate, MacMillan, David W.C

Volltext

Direct and enantioselective α-allylation of ketones via singly occupied molecular orbital (SOMO) catalysis von Mastracchio, Anthony, Warkentin, Alexander A, Walji, Abbas M, MacMillan, David W.C

Volltext

Selective MCL-1 inhibitor ABBV-467 is efficacious in tumor models but is associated with cardiac troponin increases in patients von Yuda, Junichiro, Will, Christine, Phillips, Darren C., Abraham, Linu, Alvey, Cory, Avigdor, Abraham, Buck, Wayne, Besenhofer, Lauren, Boghaert, Erwin, Cheng, Dong, Cojocari, Dan, Doyle, Kelly, Hansen, T. Matthew, Huang, Kevin, Johnson, Eric F., Judd, Andrew S., Judge, Russell A., Kalvass, John C., Kunzer, Aaron, Lam, Lloyd T., Li, Rachel, Martin, Ruth L., Mastracchio, Anthony, Mitten, Mike, Petrich, Adam, Wang, Jin, Ward, James E., Zhang, Haichao, Wang, Xilu, Wolff, Johannes E., Bell-McGuinn, Katherine M., Souers, Andrew J.

Volltext

Crystal Structure of Human Phosphodiesterase 3B:  Atomic Basis for Substrate and Inhibitor Specificity von Scapin, Giovanna, Patel, Sangita B, Chung, Christine, Varnerin, Jeffrey P, Edmondson, Scott D, Mastracchio, Anthony, Parmee, Emma R, Singh, Suresh B, Becker, Joseph W, Van der Ploeg, Lex H. T, Tota, Michael R

Volltext

Direct and enantioselective {alpha}-allylation of ketones via singly occupied molecular orbital (SOMO) catalysis von Mastracchio, Anthony, Warkentin, Alexander A, Walji, Abbas M, MacMillan, David W C

Volltext

Enabling, Decagram-Scale Synthesis of Macrocyclic MCL‑1 Inhibitor ABBV-467 von Brady, Patrick B., Sorensen, Bryan K., Risi, Roberto M., Curtin, Michael L., Mantei, Robert A., Florjancic, Alan S., Mastracchio, Anthony, Ji, Cheng, Kunzer, Aaron R., Lai, Chunqiu, Storer, Gregory E., Chan, Vincent S., Henry, Rodger F., Souers, Andrew J., Michaelides, Michael R., Judd, Andrew S., Hansen, T. Matthew

Volltext

Investigation of biaryl heterocycles as inhibitors of Wee1 kinase (vol 29, pg 1481, 2019) von Mastracchio, Anthony, Lai, Chunqiu, Torrent, Maricel, Bromberg, Kenneth, Buchanan, Fritz G., Ferguson, Debra, Bontcheva, Velitchka, Johnson, Eric F., Lasko, Loren, Maag, David, Shoemaker, Alexander R., Penning, Thomas D.

Volltext

Interspecies in vitro metabolism of the phosphodiesterase-4 (PDE4) inhibitor L-454,560 von Bateman, Kevin P., Trimble, Laird, Chauret, Nathalie, Silva, Jose, Day, Stephen, Macdonald, Dwight, Dube, Daniel, Gallant, Michel, Mastracchio, Anthony, Perrier, Helene, Girard, Yves, Nicoll-Griffith, Deborah

Volltext

Investigation of biaryl heterocycles as inhibitors of Wee1 kinase von Mastracchio, Anthony, Lai, Chunqiu, Torrent, Maricel, Bromberg, Kenneth, Buchanan, Fritz G., Ferguson, Debra, Bontcheva, Velitchka, Johnson, Eric F., Lasko, Loren, Maag, David, Shoemaker, Alexander R., Penning, Thomas D.

Volltext

Collective synthesis of natural products by means of organocascade catalysis von Jones, Spencer B, Simmons, Bryon, Mastracchio, Anthony, MacMillan, David W.C

Volltext

(2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-[1,2,4]triazolo[1,5-a]- pyridin-6-ylphenyl)butanamide:  A Selective α-Amino Amide Dipeptidyl Peptidase IV In... von Edmondson, Scott D, Mastracchio, Anthony, Mathvink, Robert J, He, Jiafang, Harper, Bart, Park, You-Jung, Beconi, Maria, Di Salvo, Jerry, Eiermann, George J, He, Huaibing, Leiting, Barbara, Leone, Joseph F, Levorse, Dorothy A, Lyons, Kathryn, Patel, Reshma A, Patel, Sangita B, Petrov, Aleksandr, Scapin, Giovanna, Shang, Jackie, Roy, Ranabir Sinha, Smith, Aaron, Wu, Joseph K, Xu, Shiyao, Zhu, Bing, Thornberry, Nancy A, Weber, Ann E

Volltext

Aminopiperidine-fused imidazoles as dipeptidyl peptidase-IV inhibitors von Edmondson, Scott D., Mastracchio, Anthony, Cox, Jason M., Eiermann, George J., He, Huaibing, Lyons, Kathryn A., Patel, Reshma A., Patel, Sangita B., Petrov, Aleksandr, Scapin, Giovanna, Wu, Joseph K., Xu, Shiyao, Zhu, Bing, Thornberry, Nancy A., Roy, Ranabir Sinha, Weber, Ann E.

Volltext

Discovery of 3-aminopiperidines as potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitors von Cox, Jason M., Harper, Bart, Mastracchio, Anthony, Leiting, Barbara, Sinha Roy, Ranabir, Patel, Reshma A., Wu, Joseph K., Lyons, Kathryn A., He, Huaibing, Xu, Shiyao, Zhu, Bing, Thornberry, Nancy A., Weber, Ann E., Edmondson, Scott D.

Volltext

Process Development and Large-Scale Synthesis of a PDE4 Inhibitor von Conlon, David A, Drahus-Paone, Antoinette, Ho, Guo-Jie, Pipik, Brenda, Helmy, Roy, McNamara, James M, Shi, Yao-Jun, Williams, J. Michael, Macdonald, Dwight, Deschênes, Denis, Gallant, Michel, Mastracchio, Anthony, Roy, Bruno, Scheigetz, John

Volltext

4-Amino cyclohexylglycine analogues as potent dipeptidyl peptidase IV inhibitors von Parmee, Emma R., He, Jiafang, Mastracchio, Anthony, Edmondson, Scott D., Colwell, Larry, Eiermann, George, Feeney, William P., Habulihaz, Bahanu, He, Huaibing, Kilburn, Ruth, Leiting, Barbara, Lyons, Kathryn, Marsilio, Frank, Patel, Reshma A., Petrov, Aleksandr, Di Salvo, Jerry, Wu, Joseph K., Thornberry, Nancy A., Weber, Ann E.

Volltext

Thiazolo[5,4-b]pyridine MALT-1 inhibitors von Kumar, Puneet, Mastracchio, Anthony, Mills, Mark, Phillips, Andrew William

Volltext bestellen

Design, synthesis, and biological evaluation of 8-biarylquinolines: A novel class of PDE4 inhibitors von Gallant, Michel, Chauret, Nathalie, Claveau, David, Day, Stephen, Deschênes, Denis, Dubé, Daniel, Huang, Zheng, Lacombe, Patrick, Laliberté, France, Lévesque, Jean-François, Liu, Susana, Macdonald, Dwight, Mancini, Joseph, Masson, Paul, Mastracchio, Anthony, Nicholson, Donald, Nicoll-Griffith, Deborah A., Perrier, Hélène, Salem, Myriam, Styhler, Angela, Young, Robert N., Girard, Yves

Volltext

Discovery of a substituted 8-arylquinoline series of PDE4 inhibitors: Structure–activity relationship, optimization, and identification of a highly potent, well tolerated, PDE4 inh... von Macdonald, Dwight, Mastracchio, Anthony, Perrier, Hélène, Dubé, Daniel, Gallant, Michel, Lacombe, Patrick, Deschênes, Denis, Roy, Bruno, Scheigetz, John, Bateman, Kevin, Li, Chun, Trimble, Laird A., Day, Stephen, Chauret, Nathalie, Nicoll-Griffith, Deborah A., Silva, Jose M., Huang, Zheng, Laliberté, France, Liu, Susana, Ethier, Diane, Pon, Doug, Muise, Eric, Boulet, Louise, Chan, Chi Chung, Styhler, Angela, Charleson, Stella, Mancini, Joseph, Masson, Paul, Claveau, David, Nicholson, Donald, Turner, Mervyn, Young, Robert N., Girard, Yves

Volltext

THIAZOLO [5,4-B] PYRIDINE MALT-1 INHIBITORS von PUNNA, Sreenivas, WANG, Le, PRATT, John, COHEN, Daniel, KUMAR, Puneet, MILLS, Mark, STOCKWELL, Jennifer, LIU, Dachun, GONG, Jane, JAIN, Tarun, YU, Yiyun, MASTRACCHIO, Anthony, PHILLIPS, Andrew

Volltext bestellen