Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges von Lovci, Michael T, Ghanem, Dana, Marr, Henry, Arnold, Justin, Gee, Sherry, Parra, Marilyn, Liang, Tiffany Y, Stark, Thomas J, Gehman, Lauren T, Hoon, Shawn, Massirer, Katlin B, Pratt, Gabriel A, Black, Douglas L, Gray, Joe W, Conboy, John G, Yeo, Gene W

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PRMT5 inhibition disrupts splicing and stemness in glioblastoma von Sachamitr, Patty, Ho, Jolene C., Ciamponi, Felipe E., Ba-Alawi, Wail, Coutinho, Fiona J., Guilhamon, Paul, Kushida, Michelle M., Cavalli, Florence M. G., Lee, Lilian, Rastegar, Naghmeh, Vu, Victoria, Sánchez-Osuna, María, Coulombe-Huntington, Jasmin, Kanshin, Evgeny, Whetstone, Heather, Durand, Mathieu, Thibault, Philippe, Hart, Kirsten, Mangos, Maria, Veyhl, Joseph, Chen, Wenjun, Tran, Nhat, Duong, Bang-Chi, Aman, Ahmed M., Che, Xinghui, Lan, Xiaoyang, Whitley, Owen, Zaslaver, Olga, Barsyte-Lovejoy, Dalia, Richards, Laura M., Restall, Ian, Caudy, Amy, Röst, Hannes L., Bonday, Zahid Quyoom, Bernstein, Mark, Das, Sunit, Cusimano, Michael D., Spears, Julian, Bader, Gary D., Pugh, Trevor J., Tyers, Mike, Lupien, Mathieu, Haibe-Kains, Benjamin, Artee Luchman, H., Weiss, Samuel, Massirer, Katlin B., Prinos, Panagiotis, Arrowsmith, Cheryl H., Dirks, Peter B.

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PRMT inhibition induces a viral mimicry response in triple-negative breast cancer von Wu, Qin, Nie, David Y., Ba-alawi, Wail, Ji, YiShuai, Zhang, ZiWen, Cruickshank, Jennifer, Haight, Jillian, Ciamponi, Felipe E., Chen, Jocelyn, Duan, Shili, Shen, Yudao, Liu, Jing, Marhon, Sajid A., Mehdipour, Parinaz, Szewczyk, Magdalena M., Dogan-Artun, Nergiz, Chen, WenJun, Zhang, Lan Xin, Deblois, Genevieve, Prinos, Panagiotis, Massirer, Katlin B., Barsyte-Lovejoy, Dalia, Jin, Jian, De Carvalho, Daniel D., Haibe-Kains, Benjamin, Wang, XiaoJia, Cescon, David W., Lupien, Mathieu, Arrowsmith, Cheryl H.

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Measuring network's entropy in ADHD: A new approach to investigate neuropsychiatric disorders von Sato, João Ricardo, Takahashi, Daniel Yasumasa, Hoexter, Marcelo Queiroz, Massirer, Katlin Brauer, Fujita, André

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An Intricate Network Involving the Argonaute ALG-1 Modulates Organismal Resistance to Oxidative Stress von Vergani-Junior, Carlos A., Moro, Raíssa De P., Pinto, Silas, De-Souza, Evandro A., Camara, Henrique, Braga, Deisi L., Tonon-da-Silva, Guilherme, Knittel, Thiago L., Ruiz, Gabriel P., Ludwig, Raissa G., Massirer, Katlin B., Mair, William B., Mori, Marcelo A.

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Regulation by let-7 and lin-4 miRNAs Results in Target mRNA Degradation von Bagga, Shveta, Bracht, John, Hunter, Shaun, Massirer, Katlin, Holtz, Janette, Eachus, Rachel, Pasquinelli, Amy E.

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A novel BRET-based assay to investigate binding and residence time of unmodified ligands to the human lysosomal ion channel TRPML1 in intact cells von Cunha, Micael R., Catta-Preta, Carolina M.C., Takarada, Jéssica E., Moreira, Gabriela A., Massirer, Katlin B., Couñago, Rafael M.

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LIN-28 co-transcriptionally binds primary let-7 to regulate miRNA maturation in Caenorhabditis elegans von Van Wynsberghe, Priscilla M, Kai, Zoya S, Massirer, Katlin B, Burton, Victoria H, Yeo, Gene W, Pasquinelli, Amy E

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A chemical screen identifies PRMT5 as a therapeutic vulnerability for paclitaxel-resistant triple-negative breast cancer von Zhang, KeJing, Wei, Juan, Zhang, SheYu, Fei, Liyan, Guo, Lu, Liu, Xueying, Ji, YiShuai, Chen, WenJun, Ciamponi, Felipe E., Chen, WeiChang, Li, MengXi, Zhai, Jie, Fu, Ting, Massirer, Katlin B., Yu, Yang, Lupien, Mathieu, Wei, Yong, Arrowsmith, Cheryl. H., Wu, Qin, Tan, WeiHong

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The miR-35-41 family of microRNAs regulates RNAi sensitivity in Caenorhabditis elegans von Massirer, Katlin B, Perez, Saida G, Mondol, Vanessa, Pasquinelli, Amy E

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An experimental target-based platform in yeast for screening Plasmodium vivax deoxyhypusine synthase inhibitors von Fernandes Silva, Suélen, Hollunder Klippel, Angélica, Sigurdardóttir, Sunniva, Mahdizadeh, Sayyed Jalil, Tiukova, Ievgeniia, Bourgard, Catarina, Salazar-Alvarez, Luis Carlos, do Amaral Prado, Heloísa Monteiro, de Araujo, Renan Vinicius, Costa, Fabio Trindade Maranhão, Bilsland, Elizabeth, King, Ross D, Brauer Massirer, Katlin, Eriksson, Leif A, Bengtson, Mário Henrique, Zanelli, Cleslei Fernando, Sunnerhagen, Per

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Development of 2-(4-pyridyl)-benzimidazoles as PKN2 chemical tools to probe cancer von Scott, Fiona, Fala, Angela M., Pennicott, Lewis E., Reuillon, Tristan D., Massirer, Katlin B., Elkins, Jonathan M., Ward, Simon E.

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Crystal structure of DRIK1, a stress-responsive receptor-like pseudokinase, reveals the molecular basis for the absence of ATP binding von Aquino, Bruno, da Silva, Viviane C H, Massirer, Katlin B, Arruda, Paulo

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LIN28 Binds Messenger RNAs at GGAGA Motifs and Regulates Splicing Factor Abundance von Wilbert, Melissa L., Huelga, Stephanie C., Kapeli, Katannya, Stark, Thomas J., Liang, Tiffany Y., Chen, Stella X., Yan, Bernice Y., Nathanson, Jason L., Hutt, Kasey R., Lovci, Michael T., Kazan, Hilal, Vu, Anthony Q., Massirer, Katlin B., Morris, Quaid, Hoon, Shawn, Yeo, Gene W.

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Development of the First Covalent Monopolar Spindle Kinase 1 (MPS1/TTK) Inhibitor von M. Serafim, Ricardo A, da Silva Santiago, André, Schwalm, Martin P, Hu, Zexi, dos Reis, Caio V, Takarada, Jessica E, Mezzomo, Priscila, Massirer, Katlin B, Kudolo, Mark, Gerstenecker, Stefan, Chaikuad, Apirat, Zender, Lars, Knapp, Stefan, Laufer, Stefan, Couñago, Rafael M, Gehringer, Matthias

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(S)‐ML‐SA1 Activates Autophagy via TRPML1‐TFEB Pathway von Cunha, Micael R., Do Amaral, Bruno S., Takarada, Jéssica E., Valderrama, Gabriel V., Batista, Andrea N. L., Batista, João M., Cass, Quezia B., Couñago, Rafael M., Massirer, Katlin B.

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UHMK1 is a novel splicing regulatory kinase von Arfelli, Vanessa C., Chang, Yun-Chien, Bagnoli, Johannes W., Kerbs, Paul, Ciamponi, Felipe E., Paz, Laissa M. da S., Pankivskyi, Serhii, de Matha Salone, Jean, Maucuer, Alexandre, Massirer, Katlin B., Enard, Wolfgang, Kuster, Bernhard, Greif, Philipp A., Archangelo, Leticia Fröhlich

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RNA interference may result in unexpected phenotypes in Caenorhabditis elegans von De-Souza, Evandro A, Camara, Henrique, Salgueiro, Willian G, Moro, Raíssa P, Knittel, Thiago L, Tonon, Guilherme, Pinto, Silas, Pinca, Ana Paula F, Antebi, Adam, Pasquinelli, Amy E, Massirer, Katlin B, Mori, Marcelo A

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Discovery of a Potent Dual SLK/STK10 Inhibitor Based on a Maleimide Scaffold von Serafim, Ricardo A. M, Sorrell, Fiona J, Berger, Benedict-Tilman, Collins, Ross J, Vasconcelos, Stanley N. S, Massirer, Katlin B, Knapp, Stefan, Bennett, James, Fedorov, Oleg, Patel, Hitesh, Zuercher, William J, Elkins, Jonathan M

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Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis von Pinto, Silas, Sato, Vitor N., De-Souza, Evandro A., Ferraz, Rafael C., Camara, Henrique, Pinca, Ana Paula F., Mazzotti, Diego R., Lovci, Michael T., Tonon, Guilherme, Lopes-Ramos, Camila M., Parmigiani, Raphael B., Wurtele, Martin, Massirer, Katlin B., Mori, Marcelo A.

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