APOE genotype alters glial activation and loss of synaptic markers in mice von Zhu, Yuangui, Nwabuisi-Heath, Evelyn, Dumanis, Sonya B., Tai, Leon M., Yu, Chunjiang, Rebeck, G. William, Ladu, Mary Jo

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Alzheimer's disease pathology in APOE transgenic mouse models: The Who, What, When, Where, Why, and How von Lewandowski, Cutler T., Maldonado Weng, Juan, LaDu, Mary Jo

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Synergistic effects of APOE and sex on the gut microbiome of young EFAD transgenic mice von Maldonado Weng, Juan, Parikh, Ishita, Naqib, Ankur, York, Jason, Green, Stefan J, Estus, Steven, LaDu, Mary Jo

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Genetics ignite focus on microglial inflammation in Alzheimer's disease von Malik, Manasi, Parikh, Ishita, Vasquez, Jared B, Smith, Conor, Tai, Leon, Bu, Guojun, LaDu, Mary Jo, Fardo, David W, Rebeck, G William, Estus, Steven

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Overexpression of Human Apolipoprotein A-I Preserves Cognitive Function and Attenuates Neuroinflammation and Cerebral Amyloid Angiopathy in a Mouse Model of Alzheimer Disease von Lewis, Terry L., Cao, Dongfeng, Lu, Hailin, Mans, Robert A., Su, Yan Ru, Jungbauer, Lisa, Linton, MacRae F., Fazio, Sergio, LaDu, Mary Jo, Li, Ling

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Murine Gut Microbiome Association With APOE Alleles von Parikh, Ishita J, Estus, Janice L, Zajac, Diana J, Malik, Manasi, Maldonado Weng, Juan, Tai, Leon M, Chlipala, George E, LaDu, Mary Jo, Green, Stefan J, Estus, Steven

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APOE genotype and sex modulate Alzheimer's disease pathology in aged EFAD transgenic mice von Balu, Deebika, Valencia-Olvera, Ana C, Islam, Zarak, Mielczarek, Clare, Hansen, Allison, Perez Ramos, Tamara M, York, Jason, LaDu, Mary Jo, Tai, Leon M

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Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Mediates Neuronal Aβ42 Uptake and Lysosomal Trafficking von Fuentealba, Rodrigo A., Liu, Qiang, Zhang, Juan, Kanekiyo, Takahisa, Hu, Xiaoyan, Lee, Jin-Moo, LaDu, Mary Jo, Bu, Guojun

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A small-molecule TLR4 antagonist reduced neuroinflammation in female E4FAD mice von Balu, Deebika, Valencia-Olvera, Ana C, Nguyen, Austin, Patnam, Mehul, York, Jason, Peri, Francesco, Neumann, Frank, LaDu, Mary Jo, Tai, Leon M

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A novel apoE-mimetic increases brain apoE levels, reduces Aβ pathology and improves memory when treated before onset of pathology in male mice that express APOE3 von Valencia-Olvera, Ana C, Balu, Deebika, Bellur, Shreya, McNally, Thomas, Saleh, Yaseen, Pham, Don, Ghura, Shivesh, York, Jason, Johansson, Jan O, LaDu, Mary Jo, Tai, Leon

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Neuronal pentraxin 1: A synaptic-derived plasma biomarker in Alzheimer's disease von Ma, Qiu-Lan, Teng, Edmond, Zuo, Xiaohong, Jones, Mychica, Teter, Bruce, Zhao, Evan Y., Zhu, Cansheng, Bilousova, Tina, Gylys, Karen H., Apostolova, Liana G., LaDu, Mary Jo, Hossain, Mir Ahamed, Frautschy, Sally A., Cole, Gregory M.

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Estradiol improves behavior in FAD transgenic mice that express APOE3 but not APOE4 after ovariectomy von Balu, Deebika, Valencia-Olvera, Ana C, Deshpande, Ashwini, Narayanam, Saharsh, Konasani, Sravya, Pattisapu, Shreya, York, Jason M, Thatcher, Gregory R J, LaDu, Mary Jo, Tai, Leon M

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Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody von Youmans, Katherine L, Tai, Leon M, Kanekiyo, Takahisa, Stine, Jr, W Blaine, Michon, Sara-Claude, Nwabuisi-Heath, Evelyn, Manelli, Arlene M, Fu, Yifan, Riordan, Sean, Eimer, William A, Binder, Lester, Bu, Guojun, Yu, Chunjiang, Hartley, Dean M, LaDu, Mary Jo

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Differential effects of oligomeric and fibrillar amyloid-β1–42 on astrocyte-mediated inflammation von White, Jill A., Manelli, Arlene M., Holmberg, Kristina H., Van Eldik, Linda J., LaDu, Mary Jo

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Metabolomic analysis of a selective ABCA1 inducer in obesogenic challenge provides a rationale for therapeutic development von Lewandowski, Cutler T., Khan, Md.Wasim, BenAissa, Manel, Dubrovskyi, Oleksii, Ackerman-Berrier, Martha, LaDu, Mary Jo, Layden, Brian T., Thatcher, Gregory R.J.

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EFAD transgenic mice as a human APOE relevant preclinical model of Alzheimerʼns disease[S] von Tai, Leon M., Balu, Deebika, Avila-Munoz, Evangelina, Abdullah, Laila, Thomas, Riya, Collins, Nicole, Valencia-Olvera, Ana Carolina, LaDu, Mary Jo

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Cognitive effects of cell-derived and synthetically derived Aβ oligomers von Reed, Miranda N, Hofmeister, Jacki J, Jungbauer, Lisa, Welzel, Alfred T, Yu, Chunjiang, Sherman, Mathew A, Lesné, Sylvain, LaDu, Mary Jo, Walsh, Dominic M, Ashe, Karen H, Cleary, James P

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Endocytic pathways mediating oligomeric Aβ42 neurotoxicity von Yu, Chunjiang, Nwabuisi-Heath, Evelyn, Laxton, Kevin, LaDu, Mary Jo

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ApoE4 delays dendritic spine formation during neuron development and accelerates loss of mature spines in vitro von Nwabuisi-Heath, Evelyn, Rebeck, G William, Ladu, Mary Jo, Yu, Chunjiang

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A dual role for apolipoprotein e in neuroinflammation: anti- and pro-inflammatory activity von Guo, Ling, LaDu, Mary Jo, Van Eldik, Linda J

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