Pharmacotoxicology of clinically-relevant concentrations of obeticholic acid in an organotypic human hepatocyte system von Dash, A., Figler, R.A., Blackman, B.R., Marukian, S., Collado, M.S., Lawson, M.J., Hoang, S.A., Mackey, A.J., Manka, D., Cole, B.K., Feaver, R.E., Sanyal, A.J., Wamhoff, B.R.

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Assessing Mechanisms of Ketoconazole and Amiodarone Induced Steatohepatitis in an Organotypic Human Primary Hepatocyte Liver Model von Figler, R, Marukian, S, Collado, M, Manka, D, Lawson, M, Mackey, A, Blackman, B, Wamhoff, B, Dash, A

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THU-276 - Assessing Mechanisms of Ketoconazole and Amiodarone Induced Steatohepatitis in an Organotypic Human Primary Hepatocyte Liver Model von Figler, R., Marukian, S., Collado, M., Manka, D., Lawson, M., Mackey, A., Blackman, B., Wamhoff, B., Dash, A.

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Plasma chemokine levels correlate with the outcome of antiviral therapy in patients with hepatitis C von Butera, David, Marukian, Svetlana, Iwamaye, Amy E., Hembrador, Edgardo, Chambers, Thomas J., Di Bisceglie, Adrian M., Charles, Edgar D., Talal, Andrew H., Jacobson, Ira M., Rice, Charles M., Dustin, Lynn B.

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A novel, multitargeted endogenous metabolic modulator composition impacts metabolism, inflammation, and fibrosis in nonalcoholic steatohepatitis-relevant primary human cell models von Daou, Nadine, Viader, Andreu, Cokol, Murat, Nitzel, Arianna, Chakravarthy, Manu V., Afeyan, Raffi, Tramontin, Tony, Marukian, Svetlana, Hamill, Michael J.

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Establishing and Validating an Ichthyosis Severity Index von Marukian, Nareh V., Deng, Yanhong, Gan, Geliang, Ren, Ivy, Thermidor, Wisblaude, Craiglow, Brittany G., Milstone, Leonard M., Choate, Keith A.

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Efficient Replication of Genotype 3a and 4a Hepatitis C Virus Replicons in Human Hepatoma Cells von SAEED, Mohsan, SCHEEL, Troels K. H, GOTTWEIN, Judith M, MARUKIAN, Svetlana, DUSTIN, Lynn B, BUKH, Jens, RICE, Charles M

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Cell culture–produced hepatitis C virus does not infect peripheral blood mononuclear cells von Marukian, Svetlana, Jones, Christopher T., Andrus, Linda, Evans, Matthew J., Ritola, Kimberly D., Charles, Edgar D., Rice, Charles M., Dustin, Lynn B.

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Recent advances in understanding ichthyosis pathogenesis [version 1; peer review: 2 approved] von Marukian, Nareh V, Choate, Keith A

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Utility of Humanized BLT Mice for Analysis of Dengue Virus Infection and Antiviral Drug Testing von Frias-Staheli, Natalia, Dorner, Marcus, Marukian, Svetlana, Billerbeck, Eva, Labitt, Rachael N, Rice, Charles M, Ploss, Alexander

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Influenza Virus Evades Innate and Adaptive Immunity via the NS1 Protein von FERNANDEZ-SESMA, Ana, MARUKIAN, Svetlana, EBERSOLE, Barbara J, KAMINSKI, Dorothy, PARK, Man-Seong, YUEN, Tony, SEALFON, Stuart C, GARCIA-SASTRE, Adolfo, MORAN, Thomas M

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Palmoplantar Keratoderma in Costello Syndrome Responsive to Acitretin von Marukian, Nareh V., Levinsohn, Jonathan L., Craiglow, Brittany G., Milstone, Leonard M., Choate, Keith A.

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Hepatitis C virus induces interferon‐λ and interferon‐stimulated genes in primary liver cultures von Marukian, Svetlana, Andrus, Linda, Sheahan, Timothy P., Jones, Christopher T., Charles, Edgar D., Ploss, Alexander, Rice, Charles M., Dustin, Lynn B.

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Transcriptional profiling suggests that Nevirapine and Ritonavir cause drug induced liver injury through distinct mechanisms in primary human hepatocytes von Terelius, Ylva, Figler, Robert A., Marukian, Svetlana, Collado, Maria S., Lawson, Mark J., Mackey, Aaron J., Manka, David, Qualls, Charles W., Blackman, Brett R., Wamhoff, Brian R., Dash, Ajit

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Interferon Lambda Alleles Predict Innate Antiviral Immune Responses and Hepatitis C Virus Permissiveness von Sheahan, Timothy, Imanaka, Naoko, Marukian, Svetlana, Dorner, Marcus, Liu, Peng, Ploss, Alexander, Rice, Charles M.

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Somatic Hypermutations Confer Rheumatoid Factor Activity in Hepatitis C Virus–Associated Mixed Cryoglobulinemia von Charles, Edgar D., Orloff, Michael I. M., Nishiuchi, Eiko, Marukian, Svetlana, Rice, Charles M., Dustin, Lynn B.

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Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells von Andrus, Linda, Marukian, Svetlana, Jones, Christopher T., Catanese, Maria Teresa, Sheahan, Timothy P., Schoggins, John W., Barry, Walter T., Dustin, Lynn B., Trehan, Kartik, Ploss, Alexander, Bhatia, Sangeeta N., Rice, Charles M.

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Expanding the Genotypic Spectrum of Bathing Suit Ichthyosis von Marukian, Nareh V, Hu, Rong-Hua, Craiglow, Brittany G, Milstone, Leonard M, Zhou, Jing, Theos, Amy, Kaymakcalan, Hande, Akkaya, Deniz A, Uitto, Jouni J, Vahidnezhad, Hassan, Youssefian, Leila, Bayliss, Susan J, Paller, Amy S, Boyden, Lynn M, Choate, Keith A

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Clonal expansion of immunoglobulin M+CD27+ B cells in HCV-associated mixed cryoglobulinemia von Charles, Edgar D., Green, Rashidah M., Marukian, Svetlana, Talal, Andrew H., Lake-Bakaar, Gerond V., Jacobson, Ira M., Rice, Charles M., Dustin, Lynn B.

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Clonal B cells in patients with hepatitis C virus–associated mixed cryoglobulinemia contain an expanded anergic CD21low B-cell subset von Charles, Edgar D., Brunetti, Claudia, Marukian, Svetlana, Ritola, Kimberly D., Talal, Andrew H., Marks, Kristen, Jacobson, Ira M., Rice, Charles M., Dustin, Lynn B.

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