Deep Brain Stimulation of the Nucleus Accumbens/Ventral Capsule for Severe and Intractable Opioid and Benzodiazepine Use Disorder von Mahoney, James J., Haut, Marc W., Hodder, Sally L., Zheng, Wanhong, Lander, Laura R., Berry, James H., Farmer, Daniel L., Marton, Jennifer L., Ranjan, Manish, Brandmeir, Nicholas J., Finomore, Victor S., Hensley, Jeremy L., Aklin, Will M., Wang, Gene-Jack, Tomasi, Dardo, Shokri-Kojori, Ehsan, Rezai, Ali R.

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Low-intensity focused ultrasound targeting the nucleus accumbens as a potential treatment for substance use disorder: safety and feasibility clinical trial von Mahoney, James J., Haut, Marc W., Carpenter, Jeffrey, Ranjan, Manish, Thompson-Lake, Daisy G. Y., Marton, Jennifer L., Zheng, Wanhong, Berry, James H., Tirumalai, Padma, Mears, Ashley, D’Haese, Pierre, Finomore, Victor S., Hodder, Sally L., Rezai, Ali R.

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Low-Intensity Focused Ultrasound Targeting the Bilateral Nucleus Accumbens as a Potential Treatment for Substance Use Disorder: A First-in-Human Report von Mahoney, James J., Thompson-Lake, Daisy G.Y., Ranjan, Manish, Marton, Jennifer L., Carpenter, Jeffrey S., Zheng, Wanhong, Berry, James H., Farmer, Daniel L., D’Haese, Pierre, Finomore, Victor S., Tirumalai, Padma, Mears, Ashley S., Suffridge, Jacob, Ames, Ashley, Hodder, Sally L., Rezai, Ali R.

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High prevalence of co-occurring substance use in individuals with opioid use disorder von Mahoney, James J., Winstanley, Erin L., Lander, Laura R., Berry, James H., Marshalek, Patrick J., Haut, Marc W., Marton, Jennifer L., Kimble, Wesley D., Armistead, Matthew, Wen, Sijin, Cai, Yilin, Hodder, Sally L.

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Safety and feasibility clinical trial of nucleus accumbens deep brain stimulation for treatment-refractory opioid use disorder von Rezai, Ali R, Mahoney, James J, Ranjan, Manish, Haut, Marc W, Zheng, Wanhong, Lander, Laura R, Berry, James H, Farmer, Daniel L, Marton, Jennifer L, Tirumalai, Padma, Mears, Ashley, Thompson-Lake, Daisy G Y, Finomore, Victor S, D'Haese, Pierre-François, Aklin, Will M, George, David T, Corrigan, John D, Hodder, Sally L

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Identifying biomarkers of drug use recurrence using wearable device technologies and phone applications von Mahoney, James J., Finomore, Victor S., Marton, Jennifer L., Ramadan, Jad, Hodder, Sally L., Thompson-Lake, Daisy G.Y., Marsh, Clay B., Koch-Gallup, Nicolas, Ranjan, Manish, Rezai, Ali R.

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Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data von Wainschtein, Pierrick, Jain, Deepti, Zheng, Zhili, Cupples, L. Adrienne, Shadyab, Aladdin H., McKnight, Barbara, Shoemaker, Benjamin M., Mitchell, Braxton D., Psaty, Bruce M., Kooperberg, Charles, Liu, Ching-Ti, Albert, Christine M., Roden, Dan, Chasman, Daniel I., Darbar, Dawood, Lloyd-Jones, Donald M., Arnett, Donna K., Regan, Elizabeth A., Boerwinkle, Eric, Rotter, Jerome I., O’Connell, Jeffrey R., Yanek, Lisa R., de Andrade, Mariza, Allison, Matthew A., McDonald, Merry-Lynn N., Chung, Mina K., Fornage, Myriam, Chami, Nathalie, Smith, Nicholas L., Ellinor, Patrick T., Vasan, Ramachandran S., Mathias, Rasika A., Loos, Ruth J. F., Rich, Stephen S., Lubitz, Steven A., Heckbert, Susan R., Redline, Susan, Guo, Xiuqing, Chen, Y. -D Ida, Laurie, Cecelia A., Hernandez, Ryan D., McGarvey, Stephen T., Goddard, Michael E., Laurie, Cathy C., North, Kari E., Lange, Leslie A., Weir, Bruce S., Yengo, Loic, Yang, Jian, Visscher, Peter M.

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Clonal haematopoiesis and risk of chronic liver disease von Wong, Waihay J., Emdin, Connor, Bick, Alexander G., Zekavat, Seyedeh M., Niroula, Abhishek, Pirruccello, James P., Dichtel, Laura, Griffin, Gabriel, Uddin, Md Mesbah, Gibson, Christopher J., Kovalcik, Veronica, Lin, Amy E., McConkey, Marie E., Vromman, Amelie, Sellar, Rob S., Kim, Peter G., Agrawal, Mridul, Weinstock, Joshua, Long, Michelle T., Yu, Bing, Banerjee, Rajarshi, Nicholls, Rowan C., Dennis, Andrea, Kelly, Matt, Loh, Po-Ru, McCarroll, Steve, Boerwinkle, Eric, Vasan, Ramachandran S., Jaiswal, Siddhartha, Johnson, Andrew D., Chung, Raymond T., Corey, Kathleen, Levy, Daniel, Ballantyne, Christie, Ebert, Benjamin L., Natarajan, Pradeep

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A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response von Luo, Yang, Kanai, Masahiro, Choi, Wanson, Li, Xinyi, Sakaue, Saori, Yamamoto, Kenichi, Ogawa, Kotaro, Gutierrez-Arcelus, Maria, Gregersen, Peter K., Stuart, Philip E., Elder, James T., Forer, Lukas, Schönherr, Sebastian, Fuchsberger, Christian, Smith, Albert V., Fellay, Jacques, Carrington, Mary, Haas, David W., Guo, Xiuqing, Palmer, Nicholette D., Chen, Yii-Der Ida, Rotter, Jerome I., Taylor, Kent D., Rich, Stephen S., Correa, Adolfo, Wilson, James G., Kathiresan, Sekar, Cho, Michael H., Metspalu, Andres, Esko, Tonu, Okada, Yukinori, Han, Buhm, McLaren, Paul J., Raychaudhuri, Soumya

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A pilot study investigating cognitive impairment associated with opioid overdose von Mahoney, James J., Winstanley, Erin L., Castillo, Felipe, Luba, Rachel, Marton, Jennifer, Alschuler, Daniel M., Liu, Ying, Comer, Sandra D.

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Effect of a Biopsychosocial Intervention or Postural Therapy on Disability and Health Care Spending Among Patients With Acute and Subacute Spine Pain: The SPINE CARE Randomized Cli... von Choudhry, Niteesh K, Fifer, Sheila, Fontanet, Constance P, Archer, Kristin R, Sears, Ellen, Bhatkhande, Gauri, Haff, Nancy, Ghazinouri, Roya, Coronado, Rogelio A, Schneider, Byron J, Butterworth, Susan W, Deogun, Harvinder, Cooper, Angelina, Hsu, Eugene, Block, Shannon, Davidson, Claudia A, Shackelford, Claude E, Goyal, Parul, Milstein, Arnold, Crum, Katherine, Scott, Jennifer, Marton, Keith, Silva, Flavio M, Obeidalla, Sarah, Robinette, Payton E, Lorenzana-DeWitt, Mario, Bair, Courtney A, Sadun, Hana J, Goldfield, Natalie, Hogewood, Luke M, Sterling, Emma K, Pickney, Cole, Koltun-Baker, Emma J, Swehla, Andrew, Ravikumar, Vishvaas, Malhotra, Sameeksha, Finney, Sabrina T, Holliday, Lynn, Moolman, Karin C, Coleman-Dockery, Shanita, Patel, Ilaben B, Angel, Federica B, Green, Jennifer K, Mitchell, Kevin, McBean, Mary R, Ghaffar, Muteeb, Ermini, Sandra R, Carr, Ana L, MacDonald, James

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Genome sequencing unveils a regulatory landscape of platelet reactivity von Keramati, Ali R., Chen, Ming-Huei, Rodriguez, Benjamin A. T., Yanek, Lisa R., Bhan, Arunoday, Gaynor, Brady J., Ryan, Kathleen, Brody, Jennifer A., Zhong, Xue, Wei, Qiang, Kammers, Kai, Kanchan, Kanika, Iyer, Kruthika, Kowalski, Madeline H., Pitsillides, Achilleas N., Cupples, L. Adrienne, Li, Bingshan, Schlaeger, Thorsten M., Shuldiner, Alan R., O’Connell, Jeffrey R., Ruczinski, Ingo, Mitchell, Braxton D., Faraday, Nauder, Taub, Margaret A., Becker, Lewis C., Lewis, Joshua P., Mathias, Rasika A., Johnson, Andrew D.

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Whole genome sequence analysis of blood lipid levels in >66,000 individuals von Selvaraj, Margaret Sunitha, Li, Xihao, Li, Zilin, Pampana, Akhil, Zhang, David Y., Park, Joseph, Aslibekyan, Stella, Bis, Joshua C., Brody, Jennifer A., Cade, Brian E., Chuang, Lee-Ming, Chung, Ren-Hua, Curran, Joanne E., de las Fuentes, Lisa, de Vries, Paul S., Duggirala, Ravindranath, Freedman, Barry I., Graff, Mariaelisa, Guo, Xiuqing, Heard-Costa, Nancy, Hidalgo, Bertha, Hwu, Chii-Min, Irvin, Marguerite R., Kelly, Tanika N., Kral, Brian G., Lange, Leslie, Li, Xiaohui, Lisa, Martin, Lubitz, Steven A., Manichaikul, Ani W., Michael, Preuss, Montasser, May E., Morrison, Alanna C., Naseri, Take, O’Connell, Jeffrey R., Palmer, Nicholette D., Peyser, Patricia A., Reupena, Muagututia S., Smith, Jennifer A., Sun, Xiao, Taylor, Kent D., Tracy, Russell P., Tsai, Michael Y., Wang, Zhe, Wang, Yuxuan, Bao, Wei, Wilkins, John T., Yanek, Lisa R., Zhao, Wei, Arnett, Donna K., Blangero, John, Boerwinkle, Eric, Bowden, Donald W., Chen, Yii-Der Ida, Correa, Adolfo, Cupples, L. Adrienne, Dutcher, Susan K., Ellinor, Patrick T., Fornage, Myriam, Gabriel, Stacey, Germer, Soren, Gibbs, Richard, He, Jiang, Kaplan, Robert C., Kardia, Sharon L. R., Kim, Ryan, Kooperberg, Charles, Loos, Ruth J. F., Viaud-Martinez, Karine A, Mathias, Rasika A., McGarvey, Stephen T., Mitchell, Braxton D., Nickerson, Deborah, North, Kari E., Psaty, Bruce M., Redline, Susan, Reiner, Alexander P., Vasan, Ramachandran S., Rich, Stephen S., Willer, Cristen, Rotter, Jerome I., Rader, Daniel J., Lin, Xihong, Peloso, Gina M., Natarajan, Pradeep

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Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals von Tahir, Usman A., Katz, Daniel H., Avila-Pachecho, Julian, Bick, Alexander G., Pampana, Akhil, Robbins, Jeremy M., Yu, Zhi, Chen, Zsu-Zsu, Benson, Mark D., Cruz, Daniel E., Ngo, Debby, Deng, Shuliang, Shi, Xu, Zheng, Shuning, Eisman, Aaron S., Farrell, Laurie, Hall, Michael E., Correa, Adolfo, Tracy, Russell P., Durda, Peter, Taylor, Kent D., Liu, Yongmei, Johnson, W. Craig, Guo, Xiuqing, Yao, Jie, Chen, Yii-Der Ida, Manichaikul, Ani W., Ruberg, Frederick L., Blaner, William S., Jain, Deepti, Bouchard, Claude, Sarzynski, Mark A., Rich, Stephen S., Rotter, Jerome I., Wang, Thomas J., Wilson, James G., Clish, Clary B., Natarajan, Pradeep, Gerszten, Robert E.

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Variant-specific inflation factors for assessing population stratification at the phenotypic variance level von Sofer, Tamar, Zheng, Xiuwen, Laurie, Cecelia A., Gogarten, Stephanie M., Brody, Jennifer A., Conomos, Matthew P., Bis, Joshua C., Thornton, Timothy A., Szpiro, Adam, O’Connell, Jeffrey R., Lange, Ethan M., Gao, Yan, Cupples, L. Adrienne, Psaty, Bruce M., Rice, Kenneth M.

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Global Guide: A Comprehensive Global Health Education Resource for Pediatric Program Directors von St Clair, Nicole E, Abdul-Mumin, Alhassan, Banker, Sumeet L, Condurache, Tania, Crouse, Heather, Haq, Heather, Helphinstine, Jill, Kazembe, Peter Nicholas, Marton, Stephanie, McQuilkin, Patricia, Pitt, Michael B, Rus, Marideth, Russ, Christiana M, Schubert, Chuck, Schutze, Gordon E, Steenhoff, Andrew P, Uwemedimo, Omolara, Watts, Jennifer, Butteris, Sabrina M

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Whole exome sequencing identifies the TNNI3K gene as a cause of familial conduction system disease and congenital junctional ectopic tachycardia von Xi, Yanwei, Honeywell, Christina, Zhang, Dapeng, Schwartzentruber, Jeremy, Beaulieu, Chandree L, Tetreault, Martine, Hartley, Taila, Marton, Jennifer, Vidal, Silvia M, Majewski, Jacek, Aravind, L, Gollob, Michael, Boycott, Kym M, Gow, Robert M

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Abstract 2483: An integrated bioinformatics pipeline for profiling cancer-immune interaction from whole exome sequencing of pembrolizumab clinical samples von Liu, Xiaoqiao, Sher, Xinwei, Lu, Hongchao, Zhuang, Jun, Zhao, Weilong, Albright, Andrew, Umemoto, Cinthia, Wudarski, Christen, Lane, Maureen, Ayers, Mark, Webber, Andrea L., Souza, Sandra C., Qiu, Ping, Levitan, Diane, Cho, Jennifer, Aurora-Garg, Deepti, Marton, Matthew, Snyder, Alexandra, Morrissey, Michael, Loboda, Andrey, Chen, Ronghua, Cristescu, Razvan

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Additive damage in the thromboxane related vasoconstriction and bradykinin relaxation of intramural coronary resistance arterioles in a rodent model of andropausal hypertension von Jósvai, Attila, Török, Marianna, Hetthéssy, Judit, Mátrai, Máté, Monori-Kiss, Anna, Makk, Jennifer, Vezér, Márton, Sára, Levente, Szabó, István, Székács, Béla, Nádasy, György L., Várbíró, Szabolcs

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A Multi-Site Collaborative Study of the Hostile Priming Effect von McCarthy, Randy, Gervais, Will, Aczel, Balazs, Al-Kire, Rosemary L, Aveyard, Mark, Marcella Baraldo, Silvia, Baruh, Lemi, Basch, Charlotte, Baumert, Anna, Behler, Anna, Bettencourt, Ann, Bitar, Adam, Bouxom, Hugo, Buck, Ashley, Cemalcilar, Zeynep, Chekroun, Peggy, Chen, Jacqueline M, del Fresno- Díaz, Ángel, Ducham, Alec, Edlund, John E, ElBassiouny, Amanda, Evans, Thomas Rhys, Ewell, Patrick J, Forscher, Patrick S, Fuglestad, Paul T, Hauck, Lauren, Hawk, Christopher E, Hermann, Anthony D, Hines, Bryon, Irumva, Mukunzi, Jordan, Lauren N, Joy-Gaba, Jennifer A, Haley, Catherine, Kamár, Pavol, Kezer, Murat, Körner, Robert, Kosaka, Muriel, Kovacs, Marton, Lair, Elicia C, Légal, Jean-Baptiste, Leighton, Dana C, Magee, Michael W, Markman, Keith, Martonik, Marcel, Müller, Martin, Norman, Jasmine B, Olsen, Jerome, Oyler, Danielle, Phills, Curtis E, Ribeiro, Gianni, Rohain, Alia, Sakaluk, John, Schütz, Astrid, Toribio-Flórez, Daniel, Tsang, Jo-Ann, Vezzoli, Michela, Williams, Caitlin, Willis, Guillermo B, Young, Jason, Zogmaister, Cristina

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