Autophagy and neuroprotection in astrocytes exposed to 6-hydroxydopamine is negatively regulated by NQO2: relevance to Parkinson’s disease von Janda, Elzbieta, Parafati, Maddalena, Martino, Concetta, Crupi, Francesco, George William, Jonahunnatha Nesson, Reybier, Karine, Arbitrio, Mariamena, Mollace, Vincenzo, Boutin, Jean A.

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Apigenin and Luteolin Regulate Autophagy by Targeting NRH-Quinone Oxidoreductase 2 in Liver Cells von Janda, Elzbieta, Martino, Concetta, Riillo, Concetta, Parafati, Maddalena, Lascala, Antonella, Mollace, Vincenzo, Boutin, Jean A.

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Qualitative and quantitative analysis of the proautophagic activity of Citrus flavonoids from Bergamot Polyphenol Fraction von Janda, Elzbieta, Salerno, Raffaele, Martino, Concetta, Lascala, Antonella, La Russa, Daniele, Oliverio, Manuela

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The multitarget FAAH inhibitor/D3 partial agonist ARN15381 decreases nicotine self-administration in male rats von Lunerti, Veronica, Li, Hongwu, Benvenuti, Federica, Shen, Qianwei, Domi, Ana, Soverchia, Laura, Concetta Di Martino, Rita Maria, Bottegoni, Giovanni, Haass-Koffler, Carolina L., Cannella, Nazzareno

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Modulation of Amyloid β-Induced Microglia Activation and Neuronal Cell Death by Curcumin and Analogues von De Lorenzi, Ersilia, Franceschini, Davide, Contardi, Cecilia, Di Martino, Rita Maria Concetta, Seghetti, Francesca, Serra, Massimo, Bisceglia, Federica, Pagetta, Andrea, Zusso, Morena, Belluti, Federica

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Phenolic 1,3‐diketones attenuate lipopolysaccharide‐induced inflammatory response by an alternative magnesium‐mediated mechanism von Zusso, Morena, Mercanti, Giulia, Belluti, Federica, Di Martino, Rita Maria Concetta, Pagetta, Andrea, Marinelli, Carla, Brun, Paola, Ragazzi, Eugenio, Lo, Rita, Stifani, Stefano, Giusti, Pietro, Moro, Stefano

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Selective Inhibition of indoleamine and tryptophan 2,3-dioxygenases: Comparative Study on Kynurenine Pathway in Cell Lines via LC-MS/MS-based Targeted Metabolomics von Villani, Salvatore, Fallarini, Silvia, Rezzi, Sarah Jane, Di Martino, Rita Maria Concetta, Aprile, Silvio, Grosso, Erika Del

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Curcumin-1,2,3-Triazole Conjugation for Targeting the Cancer Apoptosis Machinery von Seghetti, Francesca, Di Martino, Rita Maria Concetta, Catanzaro, Elena, Bisi, Alessandra, Gobbi, Silvia, Rampa, Angela, Canonico, Barbara, Montanari, Mariele, Krysko, Dmitri V, Papa, Stefano, Fimognari, Carmela, Belluti, Federica

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Analysis of proautophagic activities of Citrus flavonoids in liver cells reveals the superiority of a natural polyphenol mixture over pure flavones von Lascala, Antonella, Martino, Concetta, Parafati, Maddalena, Salerno, Raffaele, Oliverio, Manuela, Pellegrino, Daniela, Mollace, Vincenzo, Janda, Elzbieta

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Multitarget Compounds for Bipolar Disorder: From Rational Design to Preliminary Pharmacokinetic Evaluation von Di Martino, Rita Maria Concetta, Bottegoni, Giovanni, Seghetti, Francesca, Russo, Debora, Penna, Ilaria, De Simone, Alessio, Ottonello, Giuliana, Mandrup Bertozzi, Sine, Armirotti, Andrea, Bandiera, Tiziano, Belluti, Federica, Cavalli, Andrea

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Boosting phagocytosis and anti‐inflammatory phenotype in microglia mediates neuroprotection by PPARγ agonist MDG548 in Parkinson's disease models von Lecca, Daniela, Janda, Elzbieta, Mulas, Giovanna, Diana, Andrea, Martino, Concetta, Angius, Fabrizio, Spolitu, Stefano, Casu, Maria Antonietta, Simbula, Gabriella, Boi, Laura, Batetta, Barbara, Spiga, Saturnino, Carta, Anna R

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Naturally Inspired Molecules as Multifunctional Agents for Alzheimer's Disease Treatment von Rampa, Angela, Tarozzi, Andrea, Mancini, Francesca, Pruccoli, Letizia, Di Martino, Rita Maria Concetta, Gobbi, Silvia, Bisi, Alessandra, De Simone, Angela, Palomba, Francesco, Zaccheroni, Nelsi, Belluti, Federica

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Deuterium in drug discovery: progress, opportunities and challenges von Di Martino, Rita Maria Concetta, Maxwell, Brad D., Pirali, Tracey

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Molecular mechanisms of lipid- and glucose-lowering activities of bergamot flavonoids von Janda, Elzbieta, Lascala, Antonella, Martino, Concetta, Ragusa, Salvatore, Nucera, Saverio, Walker, Ross, Gratteri, Santo, Mollace, Vincenzo

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A Versatile and Sustainable Multicomponent Platform for the Synthesis of Protein Degraders: Proof-of-Concept Application to BRD4-Degrading PROTACs von Bhela, Irene Preet, Ranza, Alice, Balestrero, Federica Carolina, Serafini, Marta, Aprile, Silvio, Di Martino, Rita Maria Concetta, Condorelli, Fabrizio, Pirali, Tracey

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Versatility of the Curcumin Scaffold: Discovery of Potent and Balanced Dual BACE‑1 and GSK-3β Inhibitors von Di Martino, Rita Maria Concetta, De Simone, Angela, Andrisano, Vincenza, Bisignano, Paola, Bisi, Alessandra, Gobbi, Silvia, Rampa, Angela, Fato, Romana, Bergamini, Christian, Perez, Daniel I, Martinez, Ana, Bottegoni, Giovanni, Cavalli, Andrea, Belluti, Federica

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Investigating Drug–Target Residence Time in Kinases through Enhanced Sampling Simulations von Gobbo, Dorothea, Piretti, Valentina, Di Martino, Rita Maria Concetta, Tripathi, Shailesh Kumar, Giabbai, Barbara, Storici, Paola, Demitri, Nicola, Girotto, Stefania, Decherchi, Sergio, Cavalli, Andrea

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Novel fragment-derived colchicine-site binders as microtubule-destabilizing agents von de la Roche, Noelia Montel, Mühlethaler, Tobias, Di Martino, Rita Maria Concetta, Ortega, Jose Antonio, Gioia, Dario, Roy, Bibhas, Prota, Andrea E., Steinmetz, Michel O., Cavalli, Andrea

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The multicomponent Passerini reaction as a means of accessing diversity in structure, activity and properties: Soft and hard vanilloid/cannabinoid modulators von Lamberti, Angela, Serafini, Marta, Aprile, Silvio, Bhela, Irene Preet, Goutsiou, Georgia, Pessolano, Emanuela, Fernandez-Ballester, Gregorio, Ferrer-Montiel, Antonio, Di Martino, Rita Maria Concetta, Fernandez-Carvajal, Asia, Pirali, Tracey

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Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold von De Lorenzi, Ersilia, Seghetti, Francesca, Tarozzi, Andrea, Pruccoli, Letizia, Contardi, Cecilia, Serra, Massimo, Bisi, Alessandra, Gobbi, Silvia, Vistoli, Giulio, Gervasoni, Silvia, Argentini, Carla, Ghirardo, Giulia, Guarato, Giulia, Orso, Genny, Belluti, Federica, Di Martino, Rita Maria Concetta, Zusso, Morena

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