Abstract 452: Direct delivery of a synthetic ATP binding protein reduces ATP and induces apoptosis in Hela cells von Martinez, Selina M., Kingston, Shanika, Ngor, Arlene, Chaput, John C., Vinay, Nagaraj J., Korch, Shaleen B.

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Functional genomic landscape of acute myeloid leukaemia von Tyner, Jeffrey W., Tognon, Cristina E., Bottomly, Daniel, Wilmot, Beth, Kurtz, Stephen E., Savage, Samantha L., Long, Nicola, Schultz, Anna Reister, Traer, Elie, Abel, Melissa, Agarwal, Anupriya, Blucher, Aurora, Borate, Uma, Bryant, Jade, Burke, Russell, Carlos, Amy, Carpenter, Richie, Carroll, Joseph, Chang, Bill H., Coblentz, Cody, d’Almeida, Amanda, Cook, Rachel, Danilov, Alexey, Dao, Kim-Hien T., Degnin, Michie, Devine, Deirdre, Dibb, James, Edwards, David K., Eide, Christopher A., English, Isabel, Glover, Jason, Henson, Rachel, Ho, Hibery, Jemal, Abdusebur, Johnson, Kara, Johnson, Ryan, Junio, Brian, Kaempf, Andy, Leonard, Jessica, Lin, Chenwei, Liu, Selina Qiuying, Lo, Pierrette, Loriaux, Marc M., Luty, Samuel, Macey, Tara, MacManiman, Jason, Martinez, Jacqueline, Mori, Motomi, Nelson, Dylan, Nichols, Ceilidh, Peters, Jill, Ramsdill, Justin, Rofelty, Angela, Schuff, Robert, Searles, Robert, Segerdell, Erik, Smith, Rebecca L., Spurgeon, Stephen E., Sweeney, Tyler, Thapa, Aashis, Visser, Corinne, Wagner, Jake, Watanabe-Smith, Kevin, Werth, Kristen, Wolf, Joelle, White, Libbey, Yates, Amy, Zhang, Haijiao, Cogle, Christopher R., Collins, Robert H., Connolly, Denise C., Deininger, Michael W., Drusbosky, Leylah, Hourigan, Christopher S., Jordan, Craig T., Kropf, Patricia, Lin, Tara L., Martinez, Micaela E., Medeiros, Bruno C., Pallapati, Rachel R., Pollyea, Daniel A., Swords, Ronan T., Watts, Justin M., Weir, Scott J., Wiest, David L., Winters, Ryan M., McWeeney, Shannon K., Druker, Brian J.

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Integrative analysis of drug response and clinical outcome in acute myeloid leukemia von Bottomly, Daniel, Long, Nicola, Schultz, Anna Reister, Kurtz, Stephen E., Tognon, Cristina E., Johnson, Kara, Abel, Melissa, Agarwal, Anupriya, Avaylon, Sammantha, Benton, Erik, Blucher, Aurora, Borate, Uma, Braun, Theodore P., Brown, Jordana, Bryant, Jade, Burke, Russell, Carlos, Amy, Chang, Bill H., Cho, Hyun Jun, Christy, Stephen, Coblentz, Cody, Cohen, Aaron M., d’Almeida, Amanda, Cook, Rachel, Danilov, Alexey, Dao, Kim-Hien T., Degnin, Michie, Dibb, James, Eide, Christopher A., English, Isabel, Hagler, Stuart, Harrelson, Heath, Henson, Rachel, Ho, Hibery, Joshi, Sunil K., Junio, Brian, Kaempf, Andy, Kosaka, Yoko, Laderas, Ted, Lawhead, Matt, Lee, Hyunjung, Leonard, Jessica T., Lin, Chenwei, Lind, Evan F., Liu, Selina Qiuying, Lo, Pierrette, Loriaux, Marc M., Luty, Samuel, Maxson, Julia E., Macey, Tara, Martinez, Jacqueline, Minnier, Jessica, Monteblanco, Andrea, Mori, Motomi, Morrow, Quinlan, Nelson, Dylan, Ramsdill, Justin, Rofelty, Angela, Rogers, Alexandra, Romine, Kyle A., Ryabinin, Peter, Saultz, Jennifer N., Sampson, David A., Savage, Samantha L., Schuff, Robert, Searles, Robert, Smith, Rebecca L., Spurgeon, Stephen E., Sweeney, Tyler, Swords, Ronan T., Thapa, Aashis, Thiel-Klare, Karina, Traer, Elie, Wagner, Jake, Wilmot, Beth, Wolf, Joelle, Wu, Guanming, Yates, Amy, Zhang, Haijiao, Cogle, Christopher R., Collins, Robert H., Deininger, Michael W., Hourigan, Christopher S., Jordan, Craig T., Lin, Tara L., Martinez, Micaela E., Pallapati, Rachel R., Pollyea, Daniel A., Pomicter, Anthony D., Watts, Justin M., Weir, Scott J., Druker, Brian J., McWeeney, Shannon K., Tyner, Jeffrey W.

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Management of hyperleukocytosis and impact of leukapheresis among patients with acute myeloid leukemia (AML) on short- and long-term clinical outcomes: a large, retrospective, mult... von Stahl, Maximilian, Shallis, Rory M., Wei, Wei, Montesinos, Pau, Lengline, Etienne, Neukirchen, Judith, Bhatt, Vijaya R., Sekeres, Mikkael A., Fathi, Amir T., Konig, Heiko, Luger, Selina, Khan, Irum, Roboz, Gail J., Cluzeau, Thomas, Martínez-Cuadron, David, Raffoux, Emmanuel, Germing, Ulrich, Umakanthan, Jayadev Manikkam, Mukherjee, Sudipto, Brunner, Andrew M., Miller, Adam, McMahon, Christine M., Ritchie, Ellen K., Rodríguez-Veiga, Rebeca, Itzykson, Raphaël, Boluda, Blanca, Rabian, Florence, Tormo, Mar, Acuña-Cruz, Evelyn, Rabinovich, Emma, Yoo, Brendan, Cano, Isabel, Podoltsev, Nikolai A., Bewersdorf, Jan Philipp, Gore, Steven, Zeidan, Amer M.

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Efficacy of simtuzumab versus placebo in patients with idiopathic pulmonary fibrosis: a randomised, double-blind, controlled, phase 2 trial von Raghu, Ganesh, Dr, Brown, Kevin K, MD, Collard, Harold R, MD, Cottin, Vincent, MD, Gibson, Kevin F, MD, Kaner, Robert J, MD, Lederer, David J, MD, Martinez, Fernando J, MD, Noble, Paul W, MD, Song, Jin Woo, MD, Wells, Athol U, MD, Whelan, Timothy P M, MD, Wuyts, Wim, MD, Moreau, Emmanuel, PhD, Patterson, Scott D, PhD, Smith, Victoria, PhD, Bayly, Selina, Chien, Jason W, MD, Gong, Qi, PhD, Zhang, Jenny J, PhD, O'Riordan, Thomas G, MD

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The complex portal--an encyclopaedia of macromolecular complexes von Meldal, Birgit H M, Forner-Martinez, Oscar, Costanzo, Maria C, Dana, Jose, Demeter, Janos, Dumousseau, Marine, Dwight, Selina S, Gaulton, Anna, Licata, Luana, Melidoni, Anna N, Ricard-Blum, Sylvie, Roechert, Bernd, Skyzypek, Marek S, Tiwari, Manu, Velankar, Sameer, Wong, Edith D, Hermjakob, Henning, Orchard, Sandra

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Nanocatalytic performance of pectinase immobilized over in situ prepared magnetic nanoparticles von Navarro-López, Diego E., Bautista-Ayala, Alvaro R., Rosales-De la Cruz, Maria Fernanda, Martínez-Beltrán, Selina, Rojas-Torres, Diego E., Sanchez-Martinez, A., Ceballos-Sanchez, O., Jáuregui-Jáuregui, J.A., Lozano, Luis Marcelo, Sepúlveda-Villegas, M., Tiwari, Naveen, López-Mena, Edgar R.

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Effect of Lanadelumab Compared With Placebo on Prevention of Hereditary Angioedema Attacks: A Randomized Clinical Trial von Banerji, Aleena, Riedl, Marc A, Bernstein, Jonathan A, Cicardi, Marco, Longhurst, Hilary J, Zuraw, Bruce L, Busse, Paula J, Anderson, John, Magerl, Markus, Martinez-Saguer, Inmaculada, Davis-Lorton, Mark, Zanichelli, Andrea, Li, H. Henry, Craig, Timothy, Jacobs, Joshua, Johnston, Douglas T, Shapiro, Ralph, Yang, William H, Lumry, William R, Manning, Michael E, Schwartz, Lawrence B, Shennak, Mustafa, Soteres, Daniel, Zaragoza-Urdaz, Rafael H, Gierer, Selina, Smith, Andrew M, Tachdjian, Raffi, Wedner, H. James, Hebert, Jacques, Rehman, Syed M, Staubach, Petra, Schranz, Jennifer, Baptista, Jovanna, Nothaft, Wolfram, Maurer, Marcus

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Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans von Collier, Jack J, Guissart, Claire, Oláhová, Monika, Sasorith, Souphatta, Piron-Prunier, Florence, Suomi, Fumi, Zhang, David, Martinez-Lopez, Nuria, Leboucq, Nicolas, Bahr, Angela, Azzarello-Burri, Silvia, Reich, Selina, Schöls, Ludger, Polvikoski, Tuomo M, Meyer, Pierre, Larrieu, Lise, Schaefer, Andrew M, Alsaif, Hessa S, Alyamani, Suad, Zuchner, Stephan, Barbosa, Inês A, Deshpande, Charu, Pyle, Angela, Rauch, Anita, Synofzik, Matthis, Alkuraya, Fowzan S, Rivier, François, Ryten, Mina, McFarland, Robert, Delahodde, Agnès, McWilliams, Thomas G, Koenig, Michel, Taylor, Robert W

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Mutations in the Neuronal Vesicular SNARE VAMP2 Affect Synaptic Membrane Fusion and Impair Human Neurodevelopment von Salpietro, Vincenzo, Malintan, Nancy T., Llano-Rivas, Isabel, Spaeth, Christine G., Efthymiou, Stephanie, Striano, Pasquale, Vandrovcova, Jana, Cutrupi, Maria C., Chimenz, Roberto, David, Emanuele, Di Rosa, Gabriella, Marce-Grau, Anna, Raspall-Chaure, Miquel, Martin-Hernandez, Elena, Zara, Federico, Minetti, Carlo, Salpietro, Vincenzo, Efthymiou, Stephanie, Kriouile, Yamna, El Khorassani, Mohamed, Aguennouz, Mhammed, Karashova, Blagovesta, Avdjieva, Daniela, Kathom, Hadil, Tincheva, Radka, Van Maldergem, Lionel, Nachbauer, Wolfgang, Boesch, Sylvia, Arning, Larissa, Timmann, Dagmar, Cormand, Bru, Pérez-Dueñas, Belen, Di Rosa, Gabriella, Pironti, Erica, Goraya, Jatinder S., Sultan, Tipu, Kirmani, Salman, Ibrahim, Shahnaz, Jan, Farida, Mine, Jun, Banu, Selina, Veggiotti, Pierangelo, Ferrari, Michel D., Verrotti, Alberto, Marseglia, Gian Luigi, Savasta, Salvatore, Garavaglia, Barbara, Scuderi, Carmela, Borgione, Eugenia, Dipasquale, Valeria, Cutrupi, Maria Concetta, Portaro, Simona, Sanchez, Benigno Monteagudo, Pineda-Marfa’, Mercedes, Munell, Francina, Macaya, Alfons, Boles, Richard, Heimer, Gali, Papacostas, Savvas, Manole, Andreea, Malintan, Nancy, Zanetti, Maria Natalia, Hanna, Michael G., Rothman, James E., Kullmann, Dimitri M., Houlden, Henry, Bello, Oscar D., De Zorzi, Rita, Fortuna, Sara, Dauber, Andrew, Alkhawaja, Mariam, Sultan, Tipu, Mankad, Kshitij, Vitobello, Antonio, Thomas, Quentin, Mau-Them, Frederic Tran, Faivre, Laurence, Martinez-Azorin, Francisco, Prada, Carlos E., Macaya, Alfons, Kullmann, Dimitri M., Rothman, James E., Krishnakumar, Shyam S., Houlden, Henry

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Detecting turnover among complex communities using null models: a case study with sky-island haemosporidian parasites von Barrow, Lisa N., Bauernfeind, Selina M., Cruz, Paxton A., Williamson, Jessie L., Wiley, Daniele L., Ford, John E., Baumann, Matthew J., Brady, Serina S., Chavez, Andrea N., Gadek, Chauncey R., Galen, Spencer C., Johnson, Andrew B., Mapel, Xena M., Marroquin-Flores, Rosario A., Martinez, Taylor E., McCullough, Jenna M., McLaughlin, Jade E., Witt, Christopher C.

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Some dogs can find the payoff-dominant outcome in the Assurance game von Martínez, Mayte, Schöndorfer, Selina, Robinson, Lauren M., Brosnan, Sarah F., Range, Friederike

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Distinct molecular profiles of skull bone marrow in health and neurological disorders von Kolabas, Zeynep Ilgin, Kuemmerle, Louis B, Perneczky, Robert, Förstera, Benjamin, Ulukaya, Selin, Ali, Mayar, Kapoor, Saketh, Bartos, Laura M, Büttner, Maren, Caliskan, Ozum Sehnaz, Rong, Zhouyi, Mai, Hongcheng, Höher, Luciano, Jeridi, Denise, Molbay, Muge, Khalin, Igor, Deligiannis, Ioannis K, Negwer, Moritz, Roberts, Kenny, Simats, Alba, Carofiglio, Olga, Todorov, Mihail I, Horvath, Izabela, Ozturk, Furkan, Hummel, Selina, Biechele, Gloria, Zatcepin, Artem, Unterrainer, Marcus, Gnörich, Johannes, Roodselaar, Jay, Shrouder, Joshua, Khosravani, Pardis, Tast, Benjamin, Richter, Lisa, Díaz-Marugán, Laura, Kaltenecker, Doris, Lux, Laurin, Chen, Ying, Zhao, Shan, Rauchmann, Boris-Stephan, Sterr, Michael, Kunze, Ines, Stanic, Karen, Kan, Vanessa W Y, Besson-Girard, Simon, Katzdobler, Sabrina, Palleis, Carla, Schädler, Julia, Paetzold, Johannes C, Liebscher, Sabine, Hauser, Anja E, Gokce, Ozgun, Lickert, Heiko, Steinke, Hanno, Benakis, Corinne, Braun, Christian, Martinez-Jimenez, Celia P, Buerger, Katharina, Albert, Nathalie L, Höglinger, Günter, Levin, Johannes, Haass, Christian, Kopczak, Anna, Dichgans, Martin, Havla, Joachim, Kümpfel, Tania, Kerschensteiner, Martin, Schifferer, Martina, Simons, Mikael, Liesz, Arthur, Krahmer, Natalie, Bayraktar, Omer A, Franzmeier, Nicolai, Plesnila, Nikolaus, Erener, Suheda, Puelles, Victor G, Delbridge, Claire, Bhatia, Harsharan Singh, Hellal, Farida, Elsner, Markus, Bechmann, Ingo, Ondruschka, Benjamin, Brendel, Matthias, Theis, Fabian J, Erturk, Ali

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Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans von Collier, Jack J., Guissart, Claire, Oláhová, Monika, Sasorith, Souphatta, Piron-Prunier, Florence, Suomi, Fumi, Zhang, David, Martinez-Lopez, Nuria, Leboucq, Nicolas, Bahr, Angela, Azzarello-Burri, Silvia, Reich, Selina, Schöls, Ludger, Polvikoski, Tuomo M., Meyer, Pierre, Larrieu, Lise, Schaefer, Andrew M., Alsaif, Hessa S., Alyamani, Suad, Zuchner, Stephan, Barbosa, Inês A., Deshpande, Charu, Pyle, Angela, Rauch, Anita, Synofzik, Matthis, Alkuraya, Fowzan S., Rivier, François, Ryten, Mina, McFarland, Robert, Delahodde, Agnès, McWilliams, Thomas G., Koenig, Michel, Taylor, Robert W.

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The Biodistribution of the Spike Protein after Ad26.COV2.S Vaccination Is Unlikely to Play a Role in Vaccine-Induced Immune Thrombotic Thrombocytopenia von Marquez-Martinez, Sonia, Khan, Selina, Lubbe, Joan van der, Solforosi, Laura, Costes, Lea M M, Choi, Ying, Boedhoe, Satish, Verslegers, Mieke, Heerden, Marjolein van, Roosen, Wendy, Jonghe, Sandra De, Kristyanto, Hendy, Rezelj, Veronica, Hendriks, Jenny, Serroyen, Jan, Tolboom, Jeroen, Wegmann, Frank, Zahn, Roland C

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Intravenous Administration of Ad26.COV2.S Does Not Induce Thrombocytopenia or Thrombotic Events or Affect SARS-CoV-2 Spike Protein Bioavailability in Blood Compared with Intramuscu... von Khan, Selina, Marquez-Martinez, Sonia, Erkens, Tim, de Wilde, Adriaan, Costes, Lea M M, Vinken, Petra, De Jonghe, Sandra, Roosen, Wendy, Talia, Chiara, Chamanza, Ronnie, Serroyen, Jan, Tolboom, Jeroen, Zahn, Roland C, Wegmann, Frank

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Deciphering Factors Linked With Reduced Severe Acute Respiratory Syndrome Coronavirus 2 Susceptibility in the Swiss HIV Cohort Study von Abela, Irene A, Hauser, Anthony, Schwarzmüller, Magdalena, Pasin, Chloé, Kusejko, Katharina, Epp, Selina, Cavassini, Matthias, Battegay, Manuel, Rauch, Andri, Calmy, Alexandra, Notter, Julia, Bernasconi, Enos, Fux, Christoph A, Leuzinger, Karoline, Perreau, Matthieu, Ramette, Alban, Gottschalk, Jochen, Schindler, Eméry, Wepf, Alexander, Marconato, Maddalena, Manz, Markus G, Frey, Beat M, Braun, Dominique L, Huber, Michael, Günthard, Huldrych F, Trkola, Alexandra, Kouyos, Roger D

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Redefining Cut-Points for High Symptom Burden of the Global Initiative for Chronic Obstructive Lung Disease Classification in 18,577 Patients With Chronic Obstructive Pulmonary Dis... von Smid, Dionne E., Franssen, Frits M.E., Gonik, Maria, Miravitlles, Marc, Casanova, Ciro, Cosio, Borja G., de Lucas-Ramos, Pilar, Marin, Jose M., Martinez, Cristina, Mir, Isabel, Soriano, Joan B., de Torres, Juan P., Agusti, Alvar, Atalay, Nart B., Billington, Julia, Boutou, Afroditi K., Brighenti-Zogg, Stefanie, Chaplin, Emma, Coster, Samantha, Dodd, James W., Dürr, Selina, Fernandez-Villar, Alberto, Groenen, Miriam T.J., Guimarães, Miguel, Hejduk, Karel, Higgins, Victoria, Hopkinson, Nicholas S., Horita, Nobuyuki, Houben-Wilke, Sarah, Janssen, Daisy J.A., Jehn, Melissa, Joerres, Rudolf, Karch, Annika, Kelly, Julia L., Kim, Yu-Il, Kimura, Hiroshi, Koblizek, Vladimir, Kocks, Janwillem H., Kon, Samantha S.C., Kwon, Namhee, Ladeira, Inês, Lee, Sang-Do, Leuppi, Joerg D., Locantore, Nicholas, Lopez-Campos, José L., D-C Man, William, Maricic, Lana, Mendoza, Laura, Miedinger, David, Mihaltan, Florin, Minami, Seigo, van der Molen, Thys, Murrells, Trevor J., Nakken, Nienke, Nishijima, Yu, Norman, Ian J., Novotna, Barbora, O'Donnell, Denis E., Ogata, Yoshitaka, Pereira, Eanes D., Piercy, James, Price, David, Pothirat, Chaicharn, Raghavan, Natya, Ringbaek, Thomas, Sajkov, Dimitar, Sigari, Naseh, Singh, Sally, Small, Mark, da Silva, Guilherme F., Tanner, Rebecca J., Tsiligianni, Ioanna G., Tulek, Baykal, Tzanakis, Nikolaos, Vanfleteren, Lowie E.G.W., Watz, Henrik, Webb, Katherine A., Wouters, Emiel F.M., Xie, Guogang G., Yoshikawa, Masanori, Spruit, Martijn A.

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Antibody Response After the Third SARS-CoV-2 Vaccine in Solid Organ Transplant Recipients and People Living With HIV (COVERALL-2) von Griessbach, Alexandra, Chammartin, Frédérique, Abela, Irene A, Amico, Patrizia, Stoeckle, Marcel P, Eichenberger, Anna L, Hasse, Barbara, Braun, Dominique L, Schuurmans, Macé M, Müller, Thomas F, Tamm, Michael, Audigé, Annette, Mueller, Nicolas J, Rauch, Andri, Günthard, Huldrych F, Koller, Michael T, Trkola, Alexandra, Epp, Selina, Amstutz, Alain, Schönenberger, Christof M, Taji Heravi, Ala, Papadimitriou-Olivgeris, Matthaios, Casutt, Alessio, Manuel, Oriol, Kusejko, Katharina, Bucher, Heiner C, Briel, Matthias, Speich, Benjamin, I, Abela, K, Aebi-Popp, A, Anagnostopoulos, M, Battegay, E, Bernasconi, DL, Braun, HC, Bucher, A, Calmy, M, Cavassini, A, Ciuffi, G, Dollenmaier, M, Egger, L, Elzi, J, Fehr, J, Fellay, H, Furrer, CA, Fux, HF, Günthard, A, Hachfeld, D, Haerry, B, Hasse, HH, Hirsch, M, Hoffmann, I, Hösli, M, Huber, D, Jackson-Perry, CR, Kahlert, L, Kaiser, O, Keiser, T, Klimkait, RD, Kouyos, H, Kovari, K, Kusejko, N, Labhardt, K, Leuzinger, de Tejada B, Martinez, C, Marzolini, KJ, Metzner, N, Müller, J, Nemeth, D, Nicca, J, Notter, P, Paioni, G, Pantaleo, M, Perreau, A, Rauch, L, Salazar-Vizcaya, P, Schmid, R, Speck, M, Stöckle, P, Tarr, A, Trkola, G, Wandeler, M, Weisser, S, Yerly, Amico, Patrizia, Aubert, John-David, Banz, Vanessa, Beckmann, Sonja, Beldi, Guido, Berger, Christoph, Berishvili, Ekaterine, Berzigotti, Annalisa, Binet, Isabelle, Bochud, Pierre-Yves, Branca, Sanda, Bucher, Heiner, Catana, Emmanuelle, Cairoli, Anne, Chalandon, Yves, De Geest, Sabina, De Rougemont, Olivier

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The Parkinson's disease–linked proteins Fbxo7 and Parkin interact to mediate mitophagy von Burchell, Victoria S, Nelson, David E, Sanchez-Martinez, Alvaro, Delgado-Camprubi, Marta, Ivatt, Rachael M, Pogson, Joe H, Randle, Suzanne J, Wray, Selina, Lewis, Patrick A, Houlden, Henry, Abramov, Andrey Y, Hardy, John, Wood, Nicholas W, Whitworth, Alexander J, Laman, Heike, Plun-Favreau, Helene

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