Endothelial Cells Are Central Orchestrators of Cytokine Amplification during Influenza Virus Infection von Teijaro, John R., Walsh, Kevin B., Cahalan, Stuart, Fremgen, Daniel M., Roberts, Edward, Scott, Fiona, Martinborough, Esther, Peach, Robert, Oldstone, Michael B.A., Rosen, Hugh

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High-affinity agonists reveal recognition motifs for the MRGPRD GPCR von Wang, Chunyu, Liu, Yongfeng, Lanier, Marion, Yeager, Adam, Singh, Isha, Gumpper, Ryan H., Krumm, Brian E., DeLeon, Chelsea, Zhang, Shicheng, Boehm, Marcus, Pittner, Richard, Baron, Alain, Dvorak, Lisa, Bacon, Corinne, Shoichet, Brian K., Martinborough, Esther, Fay, Jonathan F., Cao, Can, Roth, Bryan L.

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Enantioselective Total Syntheses of (+)-Castanospermine, (+)-6-Epicastanospermine, (+)-Australine, and (+)-3-Epiaustraline von Denmark, Scott E, Martinborough, Esther A

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Substituted 6-(1-Pyrrolidine)quinolin-2(1H)-ones as Novel Selective Androgen Receptor Modulators von Martinborough, Esther, Shen, Yixing, van Oeveren, Arjan, Long, Yun Oliver, Lau, Thomas L. S, Marschke, Keith B, Chang, William Y, López, Francisco J, Vajda, Eric G, Rix, Peter J, Viveros, O. Humberto, Negro-Vilar, Andrés, Zhi, Lin

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Inhibition of mast cell degranulation by novel small molecule MRGPRX2 antagonists von Wollam, Joshua, Solomon, Michelle, Villescaz, Christiane, Lanier, Marion, Evans, Samantha, Bacon, Corinne, Freeman, David, Vasquez, Alexis, Vest, Alan, Napora, Jim, Charlot, Brittney, Cavarlez, Christine, Kim, Andrew, Dvorak, Lisa, Selfridge, Brandon, Huang, Liming, Nevarez, Andres, Dedman, Harry, Brooks, Jennifer, Frischbutter, Stefan, Metz, Martin, Serhan, Nadine, Gaudenzio, Nicolas, Timony, Gregg, Martinborough, Esther, Boehm, Marcus F., Viswanath, Veena

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Selective androgen receptor modulators based on a series of 7H-[1,4]oxazino[3,2-g]quinolin-7-ones with improved in vivo activity von LONG, Yun Oliver, HIGUCHI, Robert I, KARANEWSKY, Donald S, LIN ZHI, CAFERRO, Thomas R, LAU, Thomas L. S, MIN WU, CUMMINGS, Marquis L, MARTINBOROUGH, Esther A, MARSCHKE, Keith B, CHANG, William Y, LOPEZ, Francisco J

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MRGPRX2 Antagonist EP262 Potently Inhibits Agonist-Induced Mast Cell Degranulation In Vitro and In Vivo von Wollam, Joshua, Solomon, Michelle, Villescaz, Christiane, Lanier, Marion, Brooks, Jennifer, Kim, Andrew, Anderson, Samantha, Freeman, David, Vasquez, Alexis, Pisacane, Corinne, Charlot, Brittney, Vest, Alan, Napora, Jim, Cavarlez, Christine, Dvorak, Lisa, Selfridge, Brandon, Huang, Liming, Sainz, Marcos, Nevarez, Andres, Dedman, Harry, Timony, Gregg, Martinborough, Esther, Viswanath, Veena, Boehm, Marcus

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5 (Z) -Benzylidene -1,2 -dihydro -9 -hydroxy -10 -methoxy -2,2, 4 -trimethyl -5H-1 -aza -6 -oxa -chrysenes as non-steroidal glucocorticoid receptor modulators von ARDECKY, Robert J, HUDSON, Andrew R, LOPEZ, Francisco J, MARSCHKE, Keith B, MINER, Jeffrey N, KARANEWSKY, Donald S, NEGRO-VILAR, Andrés, LIN ZHI, PHILLIPS, Dean P, TYHONAS, John S, DECKHUT, Charlotte, LAU, Thomas L, YONGKAI LI, MARTINBOROUGH, Esther A, ROACH, Steven L, HIGUCHI, Robert I

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The Preclinical Safety Profile of RPC1063, a Selective and Potent Sphingosine 1-Phosphate 1 Receptor (S1P1R) Agonist (P01.158) von Timony, Gregg, Brooks, Jennifer, Powell, Rachel, Dedman, Harry, Scott, Fiona, Martinborough, Esther, Boehm, Marcus, Rosen, Hugh, Peach, Robert

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Metabolites of RPC1063 Contribute to In Vivo Efficacy (P05.157) von Scott, Fiona, Timony, Gregg, Brooks, Jennifer, Peach, Robert, Clemons, Bryan, Desale, Hans, Moorjani, Manisha, Brahmachary, Engurthi, Powell, Rachel, Dedman, Harry, Martinborough, Esther, Boehm, Marcus

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358 A Small Molecule S1P1 Receptor Agonist With Significant Efficacy in Animal Models of Inflammatory Bowel Disease (IBD) von Clemons, Bryan, Dedman, Harry, Powell, Rachel, Martinborough, Esther, Timony, Gregg, Peach, Robert J, Scott, Fiona L

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Sa1221 Rpc1063, a Potent, Selective S1P1 Receptor Modulator, Is Active in a Therapeutic IBD Model and Exhibits Favorable PK/PD Properties in Healthy Volunteers von Brooks, Jennifer, Peach, Robert J, Boehm, Marcus, Brahmachary, Enugurthi, Clemons, Bryan, Dedman, Harry, Desale, Hans, Gujrathi, Sheila, Huang, Liming, Hartung, Jeffrey P, Martinborough, Esther, Moorjani, Manisha, Powell, Rachel, Reinhart, Greg, Scott, Fiona L, Tamiya, Junko, Yeager, Adam, Rosen, Hugh, Timony, Gregg

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Chiral 1,1′-Binaphthyl Molecular Clefts for the Complexation of Excitatory Amino-Acid Derivatives von Martinborough, Esther, Denti, Tiziana Mordasini, Castro, Peter P., Wyman, Tara B., Knobler, Carolyn B., Diederich, François

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MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR D AND RELATED PRODUCTS AND METHODS von Lanier, Marion, Boehm, Marcus, Martinborough, Esther

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Novel selective androgen receptor modulators: SAR studies on 6-bisalkylamino-2-quinolinones von van Oeveren, Arjan, Motamedi, Mehrnoush, Martinborough, Esther, Zhao, Shuo, Shen, Yixing, West, Sarah, Chang, William, Kallel, Adam, Marschke, Keith B., López, Francisco J., Negro-Vilar, Andrés, Zhi, Lin

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SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATOR von MARSINI, Maurice, TURNBULL, Philip, MARTINBOROUGH, Esther

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SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATOR von MARSINI, Maurice, TURNBULL, Philip, MARTINBOROUGH, Esther

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SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATOR von MARSINI, Maurice, TURNBULL, Philip, MARTINBOROUGH, Esther

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QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS von SELFRIDGE, Brandon, YEAGER, Adam, BOEHM, Marcus, SAINZ, Marcos, LANIER, Marion, HUANG, Liming, MARTINBOROUGH, Esther

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Quinoline derivatives as modulators of mas-related g-protein receptor x2 and related products von LANIER Marion, MARTINBOROUGH Esther, HUANG Liming, BOEHM Marcus, SELFRIDGE Brandon, YEAGER Adam, SAINZ Marcos

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