Belantamab mafodotin for relapsed or refractory multiple myeloma (DREAMM-2): a two-arm, randomised, open-label, phase 2 study von Lonial, Sagar, Lee, Hans C, Badros, Ashraf, Trudel, Suzanne, Nooka, Ajay K, Chari, Ajai, Abdallah, Al-Ola, Callander, Natalie, Lendvai, Nikoletta, Sborov, Douglas, Suvannasankha, Attaya, Weisel, Katja, Karlin, Lionel, Libby, Edward, Arnulf, Bertrand, Facon, Thierry, Hulin, Cyrille, Kortüm, K Martin, Rodríguez-Otero, Paula, Usmani, Saad Z, Hari, Parameswaran, Baz, Rachid, Quach, Hang, Moreau, Philippe, Voorhees, Peter M, Gupta, Ira, Hoos, Axel, Zhi, Eric, Baron, January, Piontek, Trisha, Lewis, Eric, Jewell, Roxanne C, Dettman, Elisha J, Popat, Rakesh, Esposti, Simona Degli, Opalinska, Joanna, Richardson, Paul, Cohen, Adam D

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Targeted sequencing of refractory myeloma reveals a high incidence of mutations in CRBN and Ras pathway genes von Kortüm, K.Martin, Mai, Elias K., Hanafiah, Nur H., Shi, Chang-Xi, Zhu, Yuan-Xiao, Bruins, Laura, Barrio, Santiago, Jedlowski, Patrick, Merz, Maximilian, Xu, Jing, Stewart, Robert A., Andrulis, Mindaugas, Jauch, Anna, Hillengass, Jens, Goldschmidt, Hartmut, Bergsagel, P.Leif, Braggio, Esteban, Stewart, A.Keith, Raab, Marc S.

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The Impact of Tumor Heterogeneity on Diagnostics and Novel Therapeutic Strategies in Multiple Myeloma von Rasche, Leo, Kortüm, K Martin, Raab, Marc S, Weinhold, Niels

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Loss of FAM46C Promotes Cell Survival in Myeloma von Zhu, Yuan Xiao, Shi, Chang-Xin, Bruins, Laura A, Jedlowski, Patrick, Wang, Xuewei, Kortüm, K Martin, Luo, Moulun, Ahmann, Jonathan M, Braggio, Esteban, Stewart, A Keith

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European Myeloma Network recommendations on tools for the diagnosis and monitoring of multiple myeloma: what to use and when von Caers, Jo, Garderet, Laurent, Kortüm, K Martin, O'Dwyer, Michael E, van de Donk, Niels W C J, Binder, Mascha, Dold, Sandra Maria, Gay, Francesca, Corre, Jill, Beguin, Yves, Ludwig, Heinz, Larocca, Alessandra, Driessen, Christoph, Dimopoulos, Meletios A, Boccadoro, Mario, Gramatzki, Martin, Zweegman, Sonja, Einsele, Hermann, Cavo, Michele, Goldschmidt, Hartmut, Sonneveld, Pieter, Delforge, Michel, Auner, Holger W, Terpos, Evangelos, Engelhardt, Monika

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BCMA loss in the epoch of novel immunotherapy for multiple myeloma: from biology to clinical practice von Zhou, Xiang, Rasche, Leo, Kortüm, K Martin, Mersi, Julia, Einsele, Hermann

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Homozygous BCMA gene deletion in response to anti-BCMA CAR T cells in a patient with multiple myeloma von Da Vià, Matteo C., Dietrich, Oliver, Truger, Marietta, Arampatzi, Panagiota, Duell, Johannes, Heidemeier, Anke, Zhou, Xiang, Danhof, Sophia, Kraus, Sabrina, Chatterjee, Manik, Meggendorfer, Manja, Twardziok, Sven, Goebeler, Maria-Elisabeth, Topp, Max S., Hudecek, Michael, Prommersberger, Sabrina, Hege, Kristen, Kaiser, Shari, Fuhr, Viktoria, Weinhold, Niels, Rosenwald, Andreas, Erhard, Florian, Haferlach, Claudia, Einsele, Hermann, Kortüm, K. Martin, Saliba, Antoine-Emmanuel, Rasche, Leo

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Toxicities of Chimeric Antigen Receptor T Cell Therapy in Multiple Myeloma: An Overview of Experience From Clinical Trials, Pathophysiology, and Management Strategies von Zhou, Xiang, Rasche, Leo, Kortum, K. Martin, Danhof, Sophia, Hudecek, Michael, Einsele, Hermann

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Real-world treatment patterns in patients initiating third-line therapy for relapsed or refractory multiple myeloma in Germany, Italy, the United Kingdom, France, and Spain von Lehne, Moritz, Kortüm, K Martin, Ramasamy, Karthik, Zamagni, Elena, d'Estrubé, Tim, Zhuleku, Evi, Hanna, Maya, Shukla, Soham, Ghiani, Marco, Maywald, Ulf, Wilke, Thomas, Kellermann, Lenka, Perera, Sue

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Upregulation of CD38 expression on multiple myeloma cells by novel HDAC6 inhibitors is a class effect and augments the efficacy of daratumumab von García-Guerrero, Estefanía, Götz, Ralph, Doose, Sören, Sauer, Markus, Rodríguez-Gil, Alfonso, Nerreter, Thomas, Kortüm, K. Martin, Pérez-Simón, José A., Einsele, Hermann, Hudecek, Michael, Danhof, Sophia

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Spectrum and functional validation of PSMB5 mutations in multiple myeloma von Barrio, Santiago, Stühmer, Thorsten, Da-Viá, Matteo, Barrio-Garcia, Clara, Lehners, Nicola, Besse, Andrej, Cuenca, Isabel, Garitano-Trojaola, Andoni, Fink, Severin, Leich, Ellen, Chatterjee, Manik, Driessen, Christoph, Martinez-Lopez, Joaquin, Rosenwald, Andreas, Beckmann, Roland, Bargou, Ralf C., Braggio, Esteban, Stewart, A. Keith, Raab, Marc S., Einsele, Hermann, Kortüm, K. Martin

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MYC dysregulation in the progression of multiple myeloma von Misund, Kristine, Keane, Niamh, Stein, Caleb K., Asmann, Yan W., Day, Grady, Welsh, Seth, Van Wier, Scott A., Riggs, Daniel L., Ahmann, Greg, Chesi, Marta, Viswanatha, David S., Kumar, Shaji K., Dispenzieri, Angela, Gonzalez-Calle, Veronica, Kyle, Robert A., O’Dwyer, Michael, Rajkumar, S. Vincent, Kortüm, K. Martin, Keats, J. Jonathan, Fonseca, Rafael, Stewart, A. Keith, Kuehl, W. Michael, Braggio, Esteban, Bergsagel, P. Leif

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Halting the vicious cycle within the multiple myeloma ecosystem: blocking JAM-A on bone marrow endothelial cells restores angiogenic homeostasis and suppresses tumor progression von Solimando, Antonio G., Da Via, Matteo C., Leone, Patrizia, Borrelli, Paola, Croci, Giorgio A., Tabares, Paula, Brandl, Andreas, Di Lernia, Giuseppe, Bianchi, Francesco P., Tafuri, Silvio, Steinbrunn, Torsten, Balduini, Alessandra, Melaccio, Assunta, De Summa, Simona, Argentiero, Antonella, Rauert-Wunderlich, Hilka, Frassanito, Maria A., Ditonno, Paolo, Henke, Erik, Klapper, Wolfram, Ria, Roberto, Terragna, Carolina, Rasche, Leo, Rosenwald, Andreas, Kortum, K. Martin, Cavo, Michele, Ribatti, Domenico, Racanelli, Vito, Einsele, Hermann, Vacca, Angelo, Beilhack, Andreas

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Functional cure and long-term survival in multiple myeloma: how to challenge the previously impossible von Engelhardt, Monika, Kortüm, K Martin, Goldschmidt, Hartmut, Merz, Maximilian

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CXCR4-directed endoradiotherapy induces high response rates in extramedullary relapsed Multiple Myeloma von Lapa, Constantin, Herrmann, Ken, Schirbel, Andreas, Hänscheid, Heribert, Lückerath, Katharina, Schottelius, Margret, Kircher, Malte, Werner, Rudolf A, Schreder, Martin, Samnick, Samuel, Kropf, Saskia, Knop, Stefan, Buck, Andreas K, Einsele, Hermann, Wester, Hans-Juergen, Kortüm, K Martin

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Transient regulatory T-cell targeting triggers immune control of multiple myeloma and prevents disease progression von Dahlhoff, Julia, Manz, Hannah, Steinfatt, Tim, Delgado-Tascon, Julia, Seebacher, Elena, Schneider, Theresa, Wilnit, Amy, Mokhtari, Zeinab, Tabares, Paula, Böckle, David, Rasche, Leo, Martin Kortüm, K., Lutz, Manfred B., Einsele, Hermann, Brandl, Andreas, Beilhack, Andreas

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CRISPR Genome-Wide Screening Identifies Dependence on the Proteasome Subunit PSMC6 for Bortezomib Sensitivity in Multiple Myeloma von Shi, Chang-Xin, Kortüm, K Martin, Zhu, Yuan Xiao, Bruins, Laura A, Jedlowski, Patrick, Votruba, Patrick G, Luo, Moulun, Stewart, Robert A, Ahmann, Jonathan, Braggio, Esteban, Stewart, A Keith

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Minimal residual disease and imaging‐guided consolidation strategies in newly diagnosed and relapsed refractory multiple myeloma von Böckle, David, Tabares, Paula, Zhou, Xiang, Schimanski, Sven, Steinhardt, Maximilian J., Bittrich, Max, Seebacher, Elena, Ulbrich, Maria, Wilnit, Amy, Metz, Corona, Heidemeier, Anke, Bley, Thorsten, Werner, Rudolf, Buck, Andreas, Einsele, Hermann, Kortüm, K. Martin, Beilhack, Andreas, Rasche, Leo

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The use of bispecific antibodies to optimize the outcome of patients with acute leukemia, lymphoma and multiple myeloma after SCT von Einsele, Hermann, Rasche, Leo, Topp, Max S., Martin Kortüm, K., Duell, Johannes

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Changes in T‐cell subsets, preexisting cytopenias and hyperferritinaemia correlate with cytopenias after BCMA targeted CAR T‐cell therapy in relapsed/refractory multiple myeloma: R... von Zhou, Xiang, Wagner, Vivien, Scheller, Lukas, Stanojkovska, Emilia, Riedhammer, Christine, Xiao, Xianghui, Steinhardt, Maximilian Johannes, Vogt, Cornelia, Nerreter, Silvia, Eisele, Florian, John, Mara, Munawar, Umair, Kadel, Sofie‐Katrin, Mersi, Julia, Ruckdeschel, Anna, Schimanski, Sven, Haertle, Larissa, Waldschmidt, Johannes Moritz, Han, Seungbin, Topp, Max, Duell, Johannes, Einsele, Hermann, Riedel, Angela, Kortüm, K. Martin, Rasche, Leo

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