Lipopolysaccharide-Induced Increase in Intestinal Epithelial Tight Permeability Is Mediated by Toll-Like Receptor 4/Myeloid Differentiation Primary Response 88 (MyD88) Activation o... von Nighot, Meghali, Al-Sadi, Rana, Guo, Shuhong, Rawat, Manmeet, Nighot, Prashant, Watterson, Martin D., Ma, Thomas Y.

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Matrix metalloproteinase 9-induced increase in intestinal epithelial tight junction permeability contributes to the severity of experimental DSS colitis von Nighot, Prashant, Al-Sadi, Rana, Rawat, Manmeet, Guo, Shuhong, Watterson, D Martin, Ma, Thomas

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Closed head injury in an age-related Alzheimer mouse model leads to an altered neuroinflammatory response and persistent cognitive impairment von Webster, Scott J, Van Eldik, Linda J, Watterson, D Martin, Bachstetter, Adam D

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PI3Kγ stimulates a high molecular weight form of myosin light chain kinase to promote myeloid cell adhesion and tumor inflammation von Schmid, Michael C., Kang, Sang Won, Chen, Hui, Paradise, Marc, Ghebremedhin, Anghesom, Kaneda, Megan M., Chin, Shao-Ming, Do, Anh, Watterson, D. Martin, Varner, Judith A.

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Therapeutic treatment with the anti-inflammatory drug candidate MW151 may partially reduce memory impairment and normalizes hippocampal metabolic markers in a mouse model of comorb... von Braun, David J, Powell, David K, McLouth, Christopher J, Roy, Saktimayee M, Watterson, D Martin, Van Eldik, Linda J

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Selective suppression of the α isoform of p38 MAPK rescues late-stage tau pathology von Maphis, Nicole, Jiang, Shanya, Xu, Guixiang, Kokiko-Cochran, Olga N, Roy, Saktimayee M, Van Eldik, Linda J, Watterson, D Martin, Lamb, Bruce T, Bhaskar, Kiran

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Inhibition of fast axonal transport by pathogenic SOD1 involves activation of p38 MAP kinase von Morfini, Gerardo A, Bosco, Daryl A, Brown, Hannah, Gatto, Rodolfo, Kaminska, Agnieszka, Song, Yuyu, Molla, Linda, Baker, Lisa, Marangoni, M Natalia, Berth, Sarah, Tavassoli, Ehsan, Bagnato, Carolina, Tiwari, Ashutosh, Hayward, Lawrence J, Pigino, Gustavo F, Watterson, D Martin, Huang, Chun-Fang, Banker, Gary, Brown, Jr, Robert H, Brady, Scott T

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Microglial p38α MAPK is a key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Aβ) von Bachstetter, Adam D, Xing, Bin, de Almeida, Lucia, Dimayuga, Edgardo R, Watterson, D Martin, Van Eldik, Linda J

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Stasimon Contributes to the Loss of Sensory Synapses and Motor Neuron Death in a Mouse Model of Spinal Muscular Atrophy von Simon, Christian M., Van Alstyne, Meaghan, Lotti, Francesco, Bianchetti, Elena, Tisdale, Sarah, Watterson, D. Martin, Mentis, George Z., Pellizzoni, Livio

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Glia Proinflammatory Cytokine Upregulation as a Therapeutic Target for Neurodegenerative Diseases: Function-Based and Target-Based Discovery Approaches von Van Eldik, Linda J, Thompson, Wendy L, Ranaivo, Hantamalala Ralay, Behanna, Heather A, Watterson, D Martin

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Suppression of acute proinflammatory cytokine and chemokine upregulation by post-injury administration of a novel small molecule improves long-term neurologic outcome in a mouse mo... von Lloyd, Eric, Somera-Molina, Kathleen, Van Eldik, Linda J, Watterson, D Martin, Wainwright, Mark S

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Generation and behavior characterization of CaMKIIβ knockout mice von Bachstetter, Adam D, Webster, Scott J, Tu, Tao, Goulding, Danielle S, Haiech, Jacques, Watterson, D Martin, Van Eldik, Linda J

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Retention of normal glia function by an isoform-selective protein kinase inhibitor drug candidate that modulates cytokine production and cognitive outcomes von Zhou, Zhengqiu, Bachstetter, Adam D, Späni, Claudia B, Roy, Saktimayee M, Watterson, D Martin, Van Eldik, Linda J

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Development of Novel In Vivo Chemical Probes to Address CNS Protein Kinase Involvement in Synaptic Dysfunction von Watterson, D Martin, Grum-Tokars, Valerie L, Roy, Saktimayee M, Schavocky, James P, Bradaric, Brinda Desai, Bachstetter, Adam D, Xing, Bin, Dimayuga, Edgardo, Saeed, Faisal, Zhang, Hong, Staniszewski, Agnieszka, Pelletier, Jeffrey C, Minasov, George, Anderson, Wayne F, Arancio, Ottavio, Van Eldik, Linda J

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Minozac treatment prevents increased seizure susceptibility in a mouse "two-hit" model of closed skull traumatic brain injury and electroconvulsive shock-induced seizures von Chrzaszcz, MaryAnn, Venkatesan, Charu, Dragisic, Tina, Watterson, D Martin, Wainwright, Mark S

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A novel p38 alpha MAPK inhibitor suppresses brain proinflammatory cytokine up-regulation and attenuates synaptic dysfunction and behavioral deficits in an Alzheimer's disease mouse... von Munoz, Lenka, Ralay Ranaivo, Hantamalala, Roy, Saktimayee M, Hu, Wenhui, Craft, Jeffrey M, McNamara, Laurie K, Chico, Laura Wing, Van Eldik, Linda J, Watterson, D Martin

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Enhanced microglial activation and proinflammatory cytokine upregulation are linked to increased susceptibility to seizures and neurologic injury in a ‘two-hit’ seizure model von Somera-Molina, Kathleen C, Nair, Sangeetha, Van Eldik, Linda J, Watterson, D. Martin, Wainwright, Mark S

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Glial Activation Links Early‐Life Seizures and Long‐Term Neurologic Dysfunction: Evidence Using a Small Molecule Inhibitor of Proinflammatory Cytokine Upregulation von Somera‐Molina, Kathleen C., Robin, Beverley, Somera, Cherie Ann, Anderson, Christopher, Stine, Christy, Koh, Sookyong, Behanna, Heather A., Van Eldik, Linda J., Watterson, D. Martin, Wainwright, Mark S.

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MW151 Inhibited IL-1β Levels after Traumatic Brain Injury with No Effect on Microglia Physiological Responses von Bachstetter, Adam D, Zhou, Zhengqiu, Rowe, Rachel K, Xing, Bin, Goulding, Danielle S, Conley, Alyssa N, Sompol, Pradoldej, Meier, Shelby, Abisambra, Jose F, Lifshitz, Jonathan, Watterson, D Martin, Van Eldik, Linda J

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Targeting protein kinases in central nervous system disorders von Watterson, D. Martin, Chico, Laura K, Van Eldik, Linda J

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