TGFβ pathway is required for viable gestation of Fanconi anemia embryos von Rodríguez, Alfredo, Epperly, Michael, Filiatrault, Jessica, Velázquez, Martha, Yang, Chunyu, McQueen, Kelsey, Sambel, Larissa A, Nguyen, Huy, Iyer, Divya Ramalingam, Juárez, Ulises, Ayala-Zambrano, Cecilia, Martignetti, David B, Frías, Sara, Fisher, Renee, Parmar, Kalindi, Greenberger, Joel S, D'Andrea, Alan D

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A Phase I Expansion Cohort Study Evaluating the Safety and Efficacy of the CHK1 Inhibitor LY2880070 with Low-dose Gemcitabine in Patients with Metastatic Pancreatic Adenocarcinoma von Huffman, Brandon M, Feng, Hanrong, Parmar, Kalindi, Wang, Junning, Kapner, Kevin S, Kochupurakkal, Bose, Martignetti, David B, Sadatrezaei, Golbahar, Abrams, Thomas A, Biller, Leah H, Giannakis, Marios, Ng, Kimmie, Patel, Anuj K, Perez, Kimberly J, Singh, Harshabad, Rubinson, Douglas A, Schlechter, Benjamin L, Andrews, Elizabeth, Hannigan, Alison M, Dunwell, Stanley, Getchell, Zoe, Raghavan, Srivatsan, Wolpin, Brian M, Fortier, Caroline, D'Andrea, Alan D, Aguirre, Andrew J, Shapiro, Geoffrey I, Cleary, James M

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TGF[beta] pathway is required for viable gestation of Fanconi anemia embryos von Rodríguez, Alfredo, Epperly, Michael, Filiatrault, Jessica, Velázquez, Martha, Yang, Chunyu, McQueen, Kelsey, Sambel, Larissa A, Nguyen, Huy, Iyer, Divya Ramalingam, Juárez, Ulises, Ayala-Zambrano, Cecilia, Martignetti, David B, Frías, Sara, Fisher, Renee, Parmar, Kalindi, Greenberger, Joel S, D'Andrea, Alan D

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A Phase 1 Expansion Cohort Study Evaluating the Safety and Efficacy of the CHK1 Inhibitor LY2880070 with Low-Dose Gemcitabine in Metastatic Pancreatic Adenocarcinoma Patients von Huffman, Brandon M., Feng, Hanrong, Parmar, Kalindi, Wang, Junning, Kapner, Kevin S., Kochupurakkal, Bose, Martignetti, David B., Sadatrezaei, Golbahar, Abrams, Thomas A., Biller, Leah H., Giannakis, Marios, Ng, Kimmie, Patel, Anuj K., Perez, Kimberly J., Singh, Harshabad, Rubinson, Douglas A., Schlechter, Benjamin L., Andrews, Elizabeth, Hannigan, Alison M., Dunwell, Stanley, Getchell, Zoe, Raghavan, Srivatsan, Wolpin, Brian M., Fortier, Caroline, D’Andrea, Alan D., Aguirre, Andrew J., Shapiro, Geoffrey I., Cleary, James M.

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Abstract 6210: Combination of M1774 and niraparib can overcome ATR and PARP inhibitor resistance in BRCA1 mutated ovarian cancer models von Hao, Jie, Bose, Arindam, Sadatrezaei, Golbahar, Martignetti, David B., Jiao, Yuqing, da Costa, Alexandre André B., Lazaro, Jean-Bernard, Kochupurakkal, Bose, Nguyen, Huy, Parmar, Kalindi, D’Andrea, Alan D., Shapiro, Geoffrey I.

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Mutations in PDGFRB Cause Autosomal-Dominant Infantile Myofibromatosis von Martignetti, John A., Tian, Lifeng, Li, Dong, Ramirez, Maria Celeste M., Camacho-Vanegas, Olga, Camacho, Sandra Catalina, Guo, Yiran, Zand, Dina J., Bernstein, Audrey M., Masur, Sandra K., Kim, Cecilia E., Otieno, Frederick G., Hou, Cuiping, Abdel-Magid, Nada, Tweddale, Ben, Metry, Denise, Fournet, Jean-Christophe, Papp, Eniko, McPherson, Elizabeth W., Zabel, Carrie, Vaksmann, Guy, Morisot, Cyril, Keating, Brendan, Sleiman, Patrick M., Cleveland, Jeffrey A., Everman, David B., Zackai, Elaine, Hakonarson, Hakon

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Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas von Abeshouse, Adam, Armenia, Joshua, Auman, J. Todd, Bailey, Matthew H., Baker, Laurence, Balasundaram, Miruna, Balu, Saianand, Baylin, Stephen B., Behera, Madhusmita, Benz, Christopher, Bocklage, Thèrése, Boice, Lori, Bootwalla, Moiz S., Bowlby, Reanne, Boyd, Jeff, Castro, Patricia, Cherniack, Andrew D., Chudamani, Sudha, Cooper, Lee A.D., Davis, Ian J., Demetri, George D., Demicco, Elizabeth G., Ding, Li, DiSaia, Phil, Dottino, Peter, Eschbacher, Jennifer, Fedosenko, Konstantin, Ferguson, Martin L., Gao, Qingsong, Gastier-Foster, Julie M., Gerken, Mark, Godwin, Eryn M., Gordienko, Elena, Grilley-Olson, Juneko E., Gutman, David A., Hegde, Apurva M., Heiman, David I., Helsel, Carmen, Hoadley, Katherine A., Hobensack, Shital, Hornick, Jason L., Hoyle, Alan P., Iacocca, Mary, Ittmann, Michael, Jones, Steven J.M., Kim, Jaegil, Ladanyi, Marc, Lai, Phillip H., Larsson, Erik, Lee, Sanghoon, Lehmann, Kjong-Van, Levine, Douglas A., Liu, Jia, Liu, Wenbin, Liu, Eric Minwei, Lu, Yiling, Madan, Rashna, Magliocco, Anthony, Maki, Robert G., Martinez, Cathleen, Mayo, Michael, McLellan, Michael D., Mozgovoy, Evgeny, Mungall, Andrew J., Mungall, Karen, Noble, Michael S., Olvera, Narciso, Paklina, Oxana, Paulauskis, Joseph, Penny, Robert, Perou, Charles M., Perou, Amy H., Pollock, Raphael E., Ramalingam, Suresh S., Reilly, Colleen, Reynolds, Sheila M., Roach, Jeffrey, Roszik, Jason, Sadeghi, Sara, Saksena, Gordon, Sanchez-Vega, Francisco, Sander, Chris, Schein, Jacqueline E., Shelton, Candace, Shelton, Troy, Shi, Yan, Shmulevich, Ilya, Sipahimalani, Payal, Swanson, Patricia, Tarnuzzer, Roy, Thiessen, Nina, Thorne, Leigh B., Van Tine, Brian A., Verhaak, Roel, Voronina, Olga, Wang, Jing, Wise, Lisa, Wyczalkowski, Matthew, Yau, Christina, Yellapantula, Venkata

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Proteogenomic insights suggest druggable pathways in endometrial carcinoma von Dou, Yongchao, Katsnelson, Lizabeth, Gritsenko, Marina A., Hu, Yingwei, Reva, Boris, Hong, Runyu, Wang, Yi-Ting, Kolodziejczak, Iga, Lu, Rita Jui-Hsien, Tsai, Chia-Feng, Bu, Wen, Liu, Wenke, An, Eunkyung, Chu, Rosalie K., Davoli, Teresa, Demicco, Elizabeth G., Devereaux, Kelly, Dhanasekaran, Saravana M., Dottino, Peter, Hermann, Catherine E., Hiltke, Tara, Hostetter, Galen, Jędryka, Marcin, Jewell, Scott D., Kahn, Andrea G., Ku, Amy T., Kumar-Sinha, Chandan, Lazar, Alexander J., Li, Yi, Lih, Tung-Shing M., McKerrow, Wilson, Mesri, Mehdi, Monroe, Matthew E., Moon, Jamie, Newton, Chelsea, Omelchenko, Tatiana, Payne, Samuel H., Robles, Ana I., Rodriguez, Henry, Ruggles, Kelly V., Rykunov, Dmitry, Shi, Tujin, Shi, Zhiao, Tan, Jimin, Wang, Joshua M., Wen, Bo, Yi, Xinpei, Zhang, Xu, Zhao, Rui, Mutch, David, Nesvizhskii, Alexey I., Mani, D.R., Zhang, Hui, Anderson, Matthew L., Rodland, Karin D., Zhang, Bing, Antczak, Andrzej, Birrer, Michael J., Borucki, Melissa, Calinawan, Anna, Cerda, Sandra, Chesla, David, Cottingham, Sandra, Dhir, Rajiv, Domagalski, Marcin J., Edwards, Nathan J., Ellis, Matthew J., Eschbacher, Jennifer, Fam, Mina, Francis, Jesse, Freymann, John, Gabriel, Stacey, Gillette, Michael A., Godwin, Andrew K., Grady, Pamela, Hafron, Jason, Hindenach, Barbara, Hoadley, Katherine A., Huang, Jasmine, Johnson, Ashlie, Jones, Corbin D., Le, Toan, Ma'ayan, Avi, Madan, Rashna, Mareedu, Sailaja, McGarvey, Peter B., Modugno, Francesmary, Montgomery, Rebecca, Paulovich, Amanda G., Pruetz, Barbara L., Richey, Shannon, Shutack, Yvonne, Singh, Shilpi, Smith, Michael, Tobin, Matt, Um, Ki Sung, Wilson, George D., Zaalishvili, Kakhaber, Zhang, Zhen, Zhao, Grace

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Abstract 5725: The USP1 inhibitor I-138 kills BRCA1-deficient tumor cells and overcomes PARP inhibitor resistance von Da Costa, Alexandre Andre B. A., Bose, Arindam, Martignetti, David, Ayala-Zambrano, Cecilia, Ravindranathan, Ramya, Sadatrezaei, Golbahar, Jiao, Yuqing, Kochupurakkal, Bose, Nguyen, Huy, Lazaro, Jean-Bernard, Parmar, Kalindi, Shapiro, Geoffrey I., D’Andrea, Alan D.

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Abstract 2398: Precision molecular biomarkers for the surveillance of gynecologic malignancies: Rapid and efficient pipeline for the design and highly sensitive detection of circul... von Pereira, Elena B., Camacho-Vanegas, Olga, Anand, Sanya, Singh, Chanpreet, Uzilov, Andrew, Sebra, Robert, Chappell, David, Dottino, Peter, Martignetti, John A.

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