Differential Role of the RasGEFs Sos1 and Sos2 in Mouse Skin Homeostasis and Carcinogenesis von Liceras-Boillos, Pilar, Jimeno, David, García-Navas, Rósula, Lorenzo-Martín, L. Francisco, Menacho-Marquez, Mauricio, Segrelles, Carmen, Gómez, Carmela, Calzada, Nuria, Fuentes-Mateos, Rocío, Paramio, Jesús M., Bustelo, Xosé R., Baltanás, Fernando C., Santos, Eugenio

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Vagal afferents contribute to sympathoexcitation-driven metabolic dysfunctions von Lorenzo-Martín, L Francisco, Menacho-Márquez, Mauricio, Fabbiano, Salvatore, Al-Massadi, Omar, Abad, Antonio, Rodríguez-Fdez, Sonia, Sevilla, María A, Montero, María J, Diéguez, Carlos, Nogueiras, Rubén, Bustelo, Xosé R

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RAS at the Golgi antagonizes malignant transformation through PTPRκ-mediated inhibition of ERK activation von Casar, Berta, Badrock, Andrew P., Jiménez, Iñaki, Arozarena, Imanol, Colón-Bolea, Paula, Lorenzo-Martín, L. Francisco, Barinaga-Rementería, Irene, Barriuso, Jorge, Cappitelli, Vincenzo, Donoghue, Daniel J., Bustelo, Xosé R., Hurlstone, Adam, Crespo, Piero

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A Paradoxical Tumor-Suppressor Role for the Rac1 Exchange Factor Vav1 in T Cell Acute Lymphoblastic Leukemia von Robles-Valero, Javier, Lorenzo-Martín, L. Francisco, Menacho-Márquez, Mauricio, Fernández-Pisonero, Isabel, Abad, Antonio, Camós, Mireia, Toribio, María L., Espinosa, Lluis, Bigas, Anna, Bustelo, Xosé R.

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Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors von Clavaín, Laura, Fernández-Pisonero, Isabel, Movilla, Nieves, Lorenzo-Martín, L. Francisco, Nieto, Blanca, Abad, Antonio, García-Navas, Rósula, Llorente-González, Clara, Sánchez-Martín, Manuel, Vicente-Manzanares, Miguel, Santos, Eugenio, Alarcón, Balbino, García-Aznar, José M., Dosil, Mercedes, Bustelo, Xosé R.

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The Rho guanosine nucleotide exchange factors Vav2 and Vav3 modulate epidermal stem cell function von Lorenzo-Martín, L. Francisco, Menacho-Márquez, Mauricio, Fernández-Parejo, Natalia, Rodríguez-Fdez, Sonia, Pascual, Gloria, Abad, Antonio, Crespo, Piero, Dosil, Mercedes, Benitah, Salvador A., Bustelo, Xosé R.

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Vav2 pharmaco-mimetic mice reveal the therapeutic value and caveats of the catalytic inactivation of a Rho exchange factor von Lorenzo-Martín, L. Francisco, Rodríguez-Fdez, Sonia, Fabbiano, Salvatore, Abad, Antonio, García-Macías, María C., Dosil, Mercedes, Cuadrado, Myriam, Robles-Valero, Javier, Bustelo, Xosé R.

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New Functions of Vav Family Proteins in Cardiovascular Biology, Skeletal Muscle, and the Nervous System von Rodríguez-Fdez, Sonia, Lorenzo-Martín, L. Francisco, Fabbiano, Salvatore, Menacho-Márquez, Mauricio, Sauzeau, Vincent, Dosil, Mercedes, Bustelo, Xosé R.

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A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors von Fernández-Pisonero, Isabel, Clavaín, Laura, Robles-Valero, Javier, Lorenzo-Martín, L. Francisco, Caloto, Rubén, Nieto, Blanca, García-Macías, Carmen, Oeste, Clara L., Sánchez-Martín, Manuel, Abad, Antonio, Hortal, Alejandro, Caballero, Dolores, González, Marcos, Dosil, Mercedes, Alarcón, Balbino, Bustelo, Xosé R.

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CiberAMP: An R Package to Identify Differential mRNA Expression Linked to Somatic Copy Number Variations in Cancer Datasets von Caloto, Rubén, Lorenzo-Martín, L. Francisco, Quesada, Víctor, Carracedo, Arkaitz, Bustelo, Xosé R.

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Vav proteins maintain epithelial traits in breast cancer cells using miR-200c-dependent and independent mechanisms von Lorenzo-Martín, L. Francisco, Citterio, Carmen, Menacho-Márquez, Mauricio, Conde, Javier, Larive, Romain M., Rodríguez-Fdez, Sonia, García-Escudero, Ramón, Robles-Valero, Javier, Cuadrado, Myriam, Fernández-Pisonero, Isabel, Dosil, Mercedes, Sevilla, María A., Montero, María J., Fernández-Salguero, Pedro M., Paramio, Jesús M., Bustelo, Xosé R.

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Mini-colons unlock tumour development outside the body von Lorenzo-Martín, L. Francisco, Lutolf, Matthias P.

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Lysine Acetylation Reshapes the Downstream Signaling Landscape of Vav1 in Lymphocytes von Rodríguez-Fdez, Sonia, Fernández-Nevado, Lucía, Lorenzo-Martín, L Francisco, Bustelo, Xosé R

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Spatiotemporally resolved colorectal oncogenesis in mini-colons ex vivo von Lorenzo-Martín, L. Francisco, Hübscher, Tania, Bowler, Amber D., Broguiere, Nicolas, Langer, Jakob, Tillard, Lucie, Nikolaev, Mikhail, Radtke, Freddy, Lutolf, Matthias P.

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Cancer‐associated mutations in VAV1 trigger variegated signaling outputs and T‐cell lymphomagenesis von Robles‐Valero, Javier, Fernández‐Nevado, Lucía, Lorenzo‐Martín, L Francisco, Cuadrado, Myriam, Fernández‐Pisonero, Isabel, Rodríguez‐Fdez, Sonia, Astorga‐Simón, Elsa N, Abad, Antonio, Caloto, Rubén, Bustelo, Xosé R

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Vav2 catalysis-dependent pathways contribute to skeletal muscle growth and metabolic homeostasis von Rodríguez-Fdez, Sonia, Lorenzo-Martín, L. Francisco, Fernández-Pisonero, Isabel, Porteiro, Begoña, Veyrat-Durebex, Christelle, Beiroa, Daniel, Al-Massadi, Omar, Abad, Antonio, Diéguez, Carlos, Coppari, Roberto, Nogueiras, Rubén, Bustelo, Xosé R.

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Patient-derived mini-colons enable long-term modeling of tumor-microenvironment complexity von Lorenzo-Martín, L Francisco, Broguiere, Nicolas, Langer, Jakob, Tillard, Lucie, Nikolaev, Mikhail, Coukos, George, Homicsko, Krisztian, Lutolf, Matthias P

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Thymic epithelial organoids mediate T-cell development von Hübscher, Tania, Lorenzo-Martín, L Francisco, Barthlott, Thomas, Tillard, Lucie, Langer, Jakob J, Rouse, Paul, Blackburn, C Clare, Holländer, Georg, Lutolf, Matthias P

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VAV2 orchestrates the interplay between regenerative proliferation and ribogenesis in both keratinocytes and oral squamous cell carcinoma von Fernández-Parejo, Natalia, Lorenzo-Martín, L. Francisco, García-Pedrero, Juana M., Rodrigo, Juan P., Dosil, Mercedes, Bustelo, Xosé R.

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VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma von Lorenzo-Martín, L. Francisco, Fernández-Parejo, Natalia, Menacho-Márquez, Mauricio, Rodríguez-Fdez, Sonia, Robles-Valero, Javier, Zumalave, Sonia, Fabbiano, Salvatore, Pascual, Gloria, García-Pedrero, Juana M., Abad, Antonio, García-Macías, María C., González, Nazareno, Lorenzano-Menna, Pablo, Pavón, Miguel A., González-Sarmiento, Rogelio, Segrelles, Carmen, Paramio, Jesús M., Tubío, José M. C., Rodrigo, Juan P., Benitah, Salvador A., Cuadrado, Myriam, Bustelo, Xosé R.

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