Pan-cancer landscape of homologous recombination deficiency von Nguyen, Luan, W. M. Martens, John, Van Hoeck, Arne, Cuppen, Edwin

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Spatial immunophenotypes predict response to anti-PD1 treatment and capture distinct paths of T cell evasion in triple negative breast cancer von Hammerl, Dora, Martens, John W. M., Timmermans, Mieke, Smid, Marcel, Trapman-Jansen, Anita M., Foekens, Renée, Isaeva, Olga I., Voorwerk, Leonie, Balcioglu, Hayri E., Wijers, Rebecca, Nederlof, Iris, Salgado, Roberto, Horlings, Hugo, Kok, Marleen, Debets, Reno

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Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression von Ren, Jiang, Smid, Marcel, Iaria, Josephine, Salvatori, Daniela C F, van Dam, Hans, Zhu, Hong Jian, Martens, John W M, Ten Dijke, Peter

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A novel independence test for somatic alterations in cancer shows that biology drives mutual exclusivity but chance explains most co-occurrence von Canisius, Sander, Martens, John W M, Wessels, Lodewyk F A

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Integrative analysis of genomic amplification-dependent expression and loss-of-function screen identifies ASAP1 as a driver gene in triple-negative breast cancer progression von He, Jichao, McLaughlin, Ronan P., van der Beek, Lambert, Canisius, Sander, Wessels, Lodewyk, Smid, Marcel, Martens, John W. M., Foekens, John A., Zhang, Yinghui, van de Water, Bob

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MicroRNAs as possible indicators of drug sensitivity in breast cancer cell lines von Uhr, Katharina, Prager-van der Smissen, Wendy J C, Heine, Anouk A J, Ozturk, Bahar, van Jaarsveld, Marijn T M, Boersma, Antonius W M, Jager, Agnes, Wiemer, Erik A C, Smid, Marcel, Foekens, John A, Martens, John W M

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5-Fluorouracil treatment induces characteristic T>G mutations in human cancer von Christensen, Sharon, Van der Roest, Bastiaan, Besselink, Nicolle, Janssen, Roel, Boymans, Sander, Martens, John W. M., Yaspo, Marie-Laure, Priestley, Peter, Kuijk, Ewart, Cuppen, Edwin, Van Hoeck, Arne

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A kinase inhibitor screen identifies a dual cdc7/CDK9 inhibitor to sensitise triple-negative breast cancer to EGFR-targeted therapy von McLaughlin, Ronan P, He, Jichao, van der Noord, Vera E, Redel, Jevin, Foekens, John A, Martens, John W M, Smid, Marcel, Zhang, Yinghui, van de Water, Bob

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Molecular characterization of circulating tumor cells in large quantities of contaminating leukocytes by a multiplex real-time PCR von Sieuwerts, Anieta M, Kraan, Jaco, Bolt-de Vries, Joan, van der Spoel, Petra, Mostert, Bianca, Martens, John W. M, Gratama, Jan-Willem, Sleijfer, Stefan, Foekens, John A

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Anti-Epithelial Cell Adhesion Molecule Antibodies and the Detection of Circulating Normal-Like Breast Tumor Cells von Sieuwerts, Anieta M., Kraan, Jaco, Bolt, Joan, van der Spoel, Petra, Elstrodt, Fons, Schutte, Mieke, Martens, John W. M., Gratama, Jan-Willem, Sleijfer, Stefan, Foekens, John A.

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Whole genome sequencing of metastatic colorectal cancer reveals prior treatment effects and specific metastasis features von Mendelaar, Pauline A. J., Smid, Marcel, van Riet, Job, Angus, Lindsay, Labots, Mariette, Steeghs, Neeltje, Hendriks, Mathijs P., Cirkel, Geert A., van Rooijen, Johan M., Ten Tije, Albert J., Lolkema, Martijn P., Cuppen, Edwin, Sleijfer, Stefan, Martens, John W. M., Wilting, Saskia M.

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MicroRNA-30c expression level is an independent predictor of clinical benefit of endocrine therapy in advanced estrogen receptor positive breast cancer von Rodríguez-González, F. Germán, Sieuwerts, Anieta M., Smid, Marcel, Look, Maxime P., Meijer-van Gelder, Marion E., de Weerd, Vanja, Sleijfer, Stefan, Martens, John W. M., Foekens, John A.

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Multi-targeted kinase inhibition alleviates mTOR inhibitor resistance in triple-negative breast cancer von He, Jichao, McLaughlin, Ronan P., van der Noord, Vera, Foekens, John A., Martens, John W. M., van Westen, Gerard, Zhang, Yinghui, van de Water, Bob

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Integrative whole-genome and transcriptome analysis of HER2-amplified metastatic breast cancer von Verschoor, Noortje, Smid, Marcel, Jager, Agnes, Sleijfer, Stefan, Wilting, Saskia M, Martens, John W. M

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Four miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer von Foekens, John A, Sieuwerts, Anieta M, Smid, Marcel, Look, Maxime P, de Weerd, Vanja, Boersma, Antonius W.M, Klijn, Jan G.M, Wiemer, Erik A.C, Martens, John W.M

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miRNA expression profiling of 51 human breast cancer cell lines reveals subtype and driver mutation-specific miRNAs von Riaz, Muhammad, van Jaarsveld, Marijn T M, Hollestelle, Antoinette, Prager-van der Smissen, Wendy J C, Heine, Anouk A J, Boersma, Antonius W M, Liu, Jingjing, Helmijr, Jean, Ozturk, Bahar, Smid, Marcel, Wiemer, Erik A, Foekens, John A, Martens, John W M

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Complex landscapes of somatic rearrangement in human breast cancer genomes von Lau, King Wai, Mudie, Laura J, Churcher, Carol, Stratton, Michael R, Silver, Daniel P, van 't Veer, Laura, Børresen-Dale, Anne-Lise, Stebbings, Lucy A, McBride, David J, Martens, John W. M, Simpson, Jared T, Leroy, Catherine, Russnes, Hege E. G, Latimer, Calli, Jia, Mingming, Edkins, Sarah, Natrajan, Rachael, Reis-Filho, Jorge S, Varela, Ignacio, Swerdlow, Harold, Lin, Meng-Lay, Richardson, Andrea L, Pleasance, Erin D, Sieuwerts, Anieta M, Stephens, Philip J, Futreal, P. Andrew, Greenman, Chris D, Burton, John, Langerød, Anita, Quail, Michael A, Foekens, John A, Campbell, Peter J, Teague, Jon W

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HER2-low breast cancer shows a lower immune response compared to HER2-negative cases von van den Ende, Nadine S., Smid, Marcel, Timmermans, Annemieke, van Brakel, Johannes B., Hansum, Tim, Foekens, Renée, Trapman, Anita M. A. C., Heemskerk-Gerritsen, Bernadette A. M., Jager, Agnes, Martens, John W. M., van Deurzen, Carolien H. M.

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SPEN is required for Xist upregulation during initiation of X chromosome inactivation von Robert-Finestra, Teresa, Tan, Beatrice F., Mira-Bontenbal, Hegias, Timmers, Erika, Gontan, Cristina, Merzouk, Sarra, Giaimo, Benedetto Daniele, Dossin, François, van IJcken, Wilfred F. J., Martens, John W. M., Borggrefe, Tilman, Heard, Edith, Gribnau, Joost

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Validation of a Radiosensitivity Molecular Signature in Breast Cancer von ESCHRICH, Steven A, FULP, William J, BERGH, Jonas, TORRES-ROCA, Javier F, PAWITAN, Yudi, FOEKENS, John A, SMID, Marcel, MARTENS, John W. M, ECHEVARRIA, Michelle, KAMATH, Vidya, LEE, Ji-Hyun, HARRIS, Eleanor E

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