Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity von Saeed, Sadia, Quintin, Jessica, Kerstens, Hindrik H. D., Rao, Nagesha A., Aghajanirefah, Ali, Matarese, Filomena, Cheng, Shih-Chin, Ratter, Jacqueline, Berentsen, Kim, van der Ent, Martijn A., Sharifi, Nilofar, Janssen-Megens, Eva M., Ter Huurne, Menno, Mandoli, Amit, van Schaik, Tom, Ng, Aylwin, Burden, Frances, Downes, Kate, Frontini, Mattia, Kumar, Vinod, Giamarellos-Bourboulis, Evangelos J., Ouwehand, Willem H., van der Meer, Jos W. M., Joosten, Leo A. B., Wijmenga, Cisca, Martens, Joost H. A., Xavier, Ramnik J., Logie, Colin, Netea, Mihai G., Stunnenberg, Hendrik G.

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The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia von Beekman, Renée, Chapaprieta, Vicente, Russiñol, Núria, Vilarrasa-Blasi, Roser, Verdaguer-Dot, Núria, Martens, Joost H. A., Duran-Ferrer, Martí, Kulis, Marta, Serra, François, Javierre, Biola M., Wingett, Steven W., Clot, Guillem, Queirós, Ana C., Castellano, Giancarlo, Blanc, Julie, Gut, Marta, Merkel, Angelika, Heath, Simon, Vlasova, Anna, Ullrich, Sebastian, Palumbo, Emilio, Enjuanes, Anna, Martín-García, David, Beà, Sílvia, Pinyol, Magda, Aymerich, Marta, Royo, Romina, Puiggros, Montserrat, Torrents, David, Datta, Avik, Lowy, Ernesto, Kostadima, Myrto, Roller, Maša, Clarke, Laura, Flicek, Paul, Agirre, Xabier, Prosper, Felipe, Baumann, Tycho, Delgado, Julio, López-Guillermo, Armando, Fraser, Peter, Yaspo, Marie-Laure, Guigó, Roderic, Siebert, Reiner, Martí-Renom, Marc A., Puente, Xose S., López-Otín, Carlos, Gut, Ivo, Stunnenberg, Hendrik G., Campo, Elias, Martin-Subero, Jose I.

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Transcriptional diversity during lineage commitment of human blood progenitors von Chen, Lu, Kostadima, Myrto, Martens, Joost H. A., Canu, Giovanni, Garcia, Sara P., Turro, Ernest, Downes, Kate, Macaulay, Iain C., Bielczyk-Maczynska, Ewa, Coe, Sophia, Farrow, Samantha, Poudel, Pawan, Burden, Frances, Jansen, Sjoert B. G., Astle, William J., Attwood, Antony, Bariana, Tadbir, de Bono, Bernard, Breschi, Alessandra, Chambers, John C., Consortium, BRIDGE, Choudry, Fizzah A., Clarke, Laura, Coupland, Paul, van der Ent, Martijn, Erber, Wendy N., Jansen, Joop H., Favier, Rémi, Fenech, Matthew E., Foad, Nicola, Freson, Kathleen, van Geet, Chris, Gomez, Keith, Guigo, Roderic, Hampshire, Daniel, Kelly, Anne M., Kerstens, Hindrik H. D., Kooner, Jaspal S., Laffan, Michael, Lentaigne, Claire, Labalette, Charlotte, Martin, Tiphaine, Meacham, Stuart, Mumford, Andrew, Nürnberg, Sylvia, Palumbo, Emilio, van der Reijden, Bert A., Richardson, David, Sammut, Stephen J., Slodkowicz, Greg, Tamuri, Asif U., Vasquez, Louella, Voss, Katrin, Watt, Stephen, Westbury, Sarah, Flicek, Paul, Loos, Remco, Goldman, Nick, Bertone, Paul, Read, Randy J., Richardson, Sylvia, Cvejic, Ana, Soranzo, Nicole, Ouwehand, Willem H., Stunnenberg, Hendrik G., Frontini, Mattia, Rendon, Augusto

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CBX2 shapes chromatin accessibility promoting AML via p38 MAPK signaling pathway von Del Gaudio, Nunzio, Di Costanzo, Antonella, Liu, Ning Qing, Conte, Lidio, Dell'Aversana, Carmela, Bove, Guglielmo, Benedetti, Rosaria, Montella, Liliana, Ciardiello, Fortunato, Carafa, Vincenzo, Ambrosino, Concetta, Tucci, Valeria, Conte, Mariarosaria, Martens, Joost H A, Stunnenberg, Hendrik G, Nebbioso, Angela, Altucci, Lucia

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ERG and FLI1 binding sites demarcate targets for aberrant epigenetic regulation by AML1-ETO in acute myeloid leukemia von Martens, Joost H.A., Mandoli, Amit, Simmer, Femke, Wierenga, Bart-Jan, Saeed, Sadia, Singh, Abhishek A., Altucci, Lucia, Vellenga, Edo, Stunnenberg, Hendrik G.

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Regulome analysis in B-acute lymphoblastic leukemia exposes Core Binding Factor addiction as a therapeutic vulnerability von Wray, Jason P., Deltcheva, Elitza M., Boiers, Charlotta, Richardson, Simon Е, Chhetri, Jyoti Bikram, Brown, John, Gagrica, Sladjana, Guo, Yanping, Illendula, Anuradha, Martens, Joost H. A., Stunnenberg, Hendrik G., Bushweller, John H., Nimmo, Rachael, Enver, Tariq

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The acute myeloid leukemia associated AML1-ETO fusion protein alters the transcriptome and cellular progression in a single-oncogene expressing in vitro induced pluripotent stem ce... von Tijchon, Esther, Yi, Guoqiang, Mandoli, Amit, Smits, Jos G A, Ferrari, Francesco, Heuts, Branco M H, Wijnen, Falco, Kim, Bowon, Janssen-Megens, Eva M, Schuringa, Jan Jacob, Martens, Joost H A

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The AAA+ATPase RUVBL2 is essential for the oncogenic function of c-MYB in acute myeloid leukemia von Armenteros-Monterroso, Elena, Zhao, Lu, Gasparoli, Luca, Brooks, Tony, Pearce, Kerra, Mansour, Marc R., Martens, Joost H. A., de Boer, Jasper, Williams, Owen

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Identification of transcription factors dictating blood cell development using a bidirectional transcription network-based computational framework von Heuts, B. M. H., Arza-Apalategi, S., Frölich, S., Bergevoet, S. M., van den Oever, S. N., van Heeringen, S. J., van der Reijden, B. A., Martens, J. H. A.

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Clinical Images: Cholesterol crystals bursitis von Popa, C. D., Martens, H. A.

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MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in 11q23 acute myeloid leukemia von Prange, K H M, Mandoli, A, Kuznetsova, T, Wang, S-Y, Sotoca, A M, Marneth, A E, van der Reijden, B A, Stunnenberg, H G, Martens, J H A

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BLUEPRINT: mapping human blood cell epigenomes von Martens, Joost H A, Stunnenberg, Hendrik G

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Chromatin accessibility, p300, and histone acetylation define PML-RARα and AML1-ETO binding sites in acute myeloid leukemia von Saeed, Sadia, Logie, Colin, Francoijs, Kees-Jan, Frigè, Gianmaria, Romanenghi, Mauro, Nielsen, Fiona G., Raats, Lianne, Shahhoseini, Maryam, Huynen, Martijn, Altucci, Lucia, Minucci, Saverio, Martens, Joost H.A., Stunnenberg, Hendrik G.

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Potential impact of celiac disease genetic risk factors on T cell receptor signaling in gluten-specific CD4+ T cells von Bakker, Olivier B., Ramírez-Sánchez, Aarón D., Borek, Zuzanna A., de Klein, Niek, Li, Yang, Modderman, Rutger, Kooy-Winkelaar, Yvonne, Johannesen, Marie K., Matarese, Filomena, Martens, Joost H. A., Kumar, Vinod, van Bergen, Jeroen, Qiao, Shuo-Wang, Lundin, Knut E. A., Sollid, Ludvig M., Koning, Frits, Wijmenga, Cisca, Withoff, Sebo, Jonkers, Iris H.

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Inducible MLL-AF9 Expression Drives an AML Program during Human Pluripotent Stem Cell-Derived Hematopoietic Differentiation von Heuts, Branco M H, Arza-Apalategi, Saioa, Alkema, Sinne G, Tijchon, Esther, Jussen, Laura, Bergevoet, Saskia M, van der Reijden, Bert A, Martens, Joost H A

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GFI1B and LSD1 repress myeloid traits during megakaryocyte differentiation von Venhuizen, Jeron, van Bergen, Maaike G. J. M., Bergevoet, Saskia M., Gilissen, Daan, Spruijt, Cornelia G., Wingens, Laura, van den Akker, Emile, Vermeulen, Michiel, Jansen, Joop H., Martens, Joost H. A., van der Reijden, Bert A.

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Seasonal variation in BCG-induced trained immunity von Kilic, Gizem, Debisarun, Priya A., Alaswad, Ahmed, Baltissen, Marijke P., Lamers, Lieke A., de Bree, L. Charlotte J., Benn, Christine S., Aaby, Peter, Dijkstra, Helga, Lemmers, Heidi, Martens, Joost H.A., Domínguez-Andrés, Jorge, van Crevel, Reinout, Li, Yang, Xu, Cheng-Jian, Netea, Mihai G.

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HIF1/2-exerted control over glycolytic gene expression is not functionally relevant for glycolysis in human leukemic stem/progenitor cells von Wierenga, Albertus T J, Cunningham, Alan, Erdem, Ayşegül, Lopera, Nuria Vilaplana, Brouwers-Vos, Annet Z, Pruis, Maurien, Mulder, André B, Günther, Ulrich L, Martens, Joost H A, Vellenga, Edo, Schuringa, Jan Jacob

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Suv39h-Dependent H3K9me3 Marks Intact Retrotransposons and Silences LINE Elements in Mouse Embryonic Stem Cells von Bulut-Karslioglu, Aydan, De La Rosa-Velázquez, Inti A., Ramirez, Fidel, Barenboim, Maxim, Onishi-Seebacher, Megumi, Arand, Julia, Galán, Carmen, Winter, Georg E., Engist, Bettina, Gerle, Borbala, O’Sullivan, Roderick J., Martens, Joost H.A., Walter, Jörn, Manke, Thomas, Lachner, Monika, Jenuwein, Thomas

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