Addition of durvalumab (Dur) upon progression to bevacizumab (Bev) maintenance in advanced HER2-negative (HERNEG) breast cancer (BC): Safety, efficacy and biomarkers von Quintela-Fandino, M., Manso Sànchez, L.M., Holgado Martín, E., Moreno, M.C., Morales Murillo, S., Bermejo De Las Heras, B., Malon Gimenez, D., Colomer Bosch, R., Gonzalez Cortijo, L., Hornedo, J., Mouron, S., Muñoz, M., Escudero, S., Blanco, R., Mañes, S.

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1871P Overcoming barriers in opioid-induced constipation management von Holgado Martín, E., Blasco Cordellat, A., García-Castaño, A., Villatoro, R., Guix Arnau, M.

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72OAddition of durvalumab (Dur) upon progression to bevacizumab (Bev) maintenance in advanced HER2-negative (HERNEG) breast cancer (BC): Safety, efficacy and biomarkers von Quintela-Fandino, M, Manso Sànchez, L M, Holgado Martín, E, Moreno, M C, Morales Murillo, S, Bermejo De Las Heras, B, Malon Gimenez, D, Colomer Bosch, R, Gonzalez Cortijo, L, Hornedo, J, Mouron, S, Muñoz, M, Escudero, S, Blanco, R, Mañes, S

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191MO KEYNOTE-355: Outcomes in patients who discontinued chemotherapy before pembrolizumab and in patients with immune-mediated AEs von Rugo, H.S., Cescon, D.W., Im, S-A., Yusof, M. Md, Araneda, C.E. Gallardo, Lipatov, O., Cruz, F., Barrios, C.H., Hegg, R., Martín, E. Holgado, Torregroza Otero, M.A., Turner, N., Árkosy, P.F., Tarnawski, R., Karantza, V., Pan, W., Guo, Z., Cortés, J.

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Nivolumab versus Docetaxel in Advanced Nonsquamous Non–Small-Cell Lung Cancer von Borghaei, Hossein, Paz-Ares, Luis, Horn, Leora, Spigel, David R, Steins, Martin, Ready, Neal E, Chow, Laura Q, Vokes, Everett E, Felip, Enriqueta, Holgado, Esther, Barlesi, Fabrice, Kohlhäufl, Martin, Arrieta, Oscar, Burgio, Marco Angelo, Fayette, Jérôme, Lena, Hervé, Poddubskaya, Elena, Gerber, David E, Gettinger, Scott N, Rudin, Charles M, Rizvi, Naiyer, Crinò, Lucio, Blumenschein, George R, Antonia, Scott J, Dorange, Cécile, Harbison, Christopher T, Graf Finckenstein, Friedrich, Brahmer, Julie R

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Nivolumab versus Docetaxel in Advanced Squamous-Cell Non–Small-Cell Lung Cancer von Brahmer, Julie, Reckamp, Karen L, Baas, Paul, Crinò, Lucio, Eberhardt, Wilfried E.E, Poddubskaya, Elena, Antonia, Scott, Pluzanski, Adam, Vokes, Everett E, Holgado, Esther, Waterhouse, David, Ready, Neal, Gainor, Justin, Arén Frontera, Osvaldo, Havel, Libor, Steins, Martin, Garassino, Marina C, Aerts, Joachim G, Domine, Manuel, Paz-Ares, Luis, Reck, Martin, Baudelet, Christine, Harbison, Christopher T, Lestini, Brian, Spigel, David R

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CB2 cannabinoid receptors as an emerging target for demyelinating diseases: from neuroimmune interactions to cell replacement strategies von Arévalo‐Martín, Á, García‐Ovejero, D, Gómez, O, Rubio‐Araiz, A, Navarro‐Galve, B, Guaza, C, Molina‐Holgado, E, Molina‐Holgado, F

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Cannabinoid Receptor 1 associates to different molecular complexes during GABAergic neuron maturation von Molina‐Holgado, Eduardo, Paniagua‐Torija, Beatriz, Arevalo‐Martin, Angel, Moreno‐Luna, Rafael, Esteban, Pedro F., Le, Minh Quynh Uyen, Del Cerro, Maria del Mar, Garcia‐Ovejero, Daniel

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Nivolumab Versus Docetaxel in Previously Treated Patients With Advanced Non-Small-Cell Lung Cancer: Two-Year Outcomes From Two Randomized, Open-Label, Phase III Trials (CheckMate 0... von Horn, Leora, Spigel, David R, Vokes, Everett E, Holgado, Esther, Ready, Neal, Steins, Martin, Poddubskaya, Elena, Borghaei, Hossein, Felip, Enriqueta, Paz-Ares, Luis, Pluzanski, Adam, Reckamp, Karen L, Burgio, Marco A, Kohlhäeufl, Martin, Waterhouse, David, Barlesi, Fabrice, Antonia, Scott, Arrieta, Oscar, Fayette, Jérôme, Crinò, Lucio, Rizvi, Naiyer, Reck, Martin, Hellmann, Matthew D, Geese, William J, Li, Ang, Blackwood-Chirchir, Anne, Healey, Diane, Brahmer, Julie, Eberhardt, Wilfried E E

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Cannabinoids Promote Oligodendrocyte Progenitor Survival: Involvement of Cannabinoid Receptors and Phosphatidylinositol-3 Kinase/Akt Signaling von Molina-Holgado, Eduardo, Vela, Jose M, Arevalo-Martin, Angel, Almazan, Guillermina, Molina-Holgado, Francisco, Borrell, Jose, Guaza, Carmen

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Autologous intramyocardial injection of cultured skeletal muscle-derived stem cells in patients with non-acute myocardial infarction von Herreros, Jesús, Prósper, Felipe, Perez, Ana, Gavira, Juan J, Garcia-Velloso, María José, Barba, Joaquín, Sánchez, Pedro L, Cañizo, Consuelo, Rábago, Gregorio, Martí-Climent, Josep M, Hernández, Milagros, López-Holgado, Natalia, González-Santos, José María, Martín-Luengo, Cándido, Alegria, Eduardo

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Spinal cord injury induces a long-lasting upregulation of interleukin-1β in astrocytes around the central canal von Paniagua-Torija, B, Arevalo-Martin, A, Molina-Holgado, E, Molina-Holgado, F, Garcia-Ovejero, D

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Antitumor activity of lurbinectedin (PM01183) and doxorubicin in relapsed small-cell lung cancer: results from a phase I study von Calvo, E., Moreno, V., Flynn, M., Holgado, E., Olmedo, M.E., Lopez Criado, M.P., Kahatt, C., Lopez-Vilariño, J.A., Siguero, M., Fernandez-Teruel, C., Cullell-Young, M., Soto Matos-Pita, A., Forster, M.

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CB 2 cannabinoid receptors as an emerging target for demyelinating diseases: from neuroimmune interactions to cell replacement strategies von Arévalo‐Martín, Á, García‐Ovejero, D, Gómez, O, Rubio‐Araiz, A, Navarro‐Galve, B, Guaza, C, Molina‐Holgado, E, Molina‐Holgado, F

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Heterogeneity of the Endocannabinoid System Between Cerebral Cortex and Spinal Cord Oligodendrocytes von Moreno-Luna, R., Esteban, P. F., Paniagua-Torija, B., Arevalo-Martin, A., Garcia-Ovejero, D., Molina-Holgado, E.

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ANMerge: A Comprehensive and Accessible Alzheimer's Disease Patient-Level Dataset von Birkenbihl, C, Westwood, S, Shi, L, Nevado-Holgado, A, Westman, E, Lovestone, S, Hofmann-Apitius, M

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A giant exoplanet orbiting a very-low-mass star challenges planet formation models von Morales, J C, Mustill, A J, Ribas, I, Davies, M B, Reiners, A, Bauer, F F, Kossakowski, D, Herrero, E, Rodríguez, E, López-González, M J, Rodríguez-López, C, Béjar, V J S, González-Cuesta, L, Luque, R, Pallé, E, Perger, M, Baroch, D, Johansen, A, Klahr, H, Mordasini, C, Anglada-Escudé, G, Caballero, J A, Cortés-Contreras, M, Dreizler, S, Lafarga, M, Nagel, E, Passegger, V M, Reffert, S, Rosich, A, Schweitzer, A, Tal-Or, L, Trifonov, T, Zechmeister, M, Quirrenbach, A, Amado, P J, Guenther, E W, Hagen, H-J, Henning, T, Jeffers, S V, Kaminski, A, Kürster, M, Montes, D, Seifert, W, Abellán, F J, Abril, M, Aceituno, J, Aceituno, F J, Alonso-Floriano, F J, Ammler-von Eiff, M, Antona, R, Arroyo-Torres, B, Azzaro, M, Barrado, D, Becerril-Jarque, S, Benítez, D, Berdiñas, Z M, Bergond, G, Brinkmöller, M, Del Burgo, C, Burn, R, Calvo-Ortega, R, Cano, J, Cárdenas, M C, Guillén, C Cardona, Carro, J, Casal, E, Casanova, V, Casasayas-Barris, N, Chaturvedi, P, Cifuentes, C, Claret, A, Colomé, J, Czesla, S, Díez-Alonso, E, Dorda, R, Emsenhuber, A, Fernández, M, Fernández-Martín, A, Ferro, I M, Fuhrmeister, B, Galadí-Enríquez, D, Cava, I Gallardo, Vargas, M L García, Garcia-Piquer, A, Gesa, L, González-Álvarez, E, Hernández, J I González, González-Peinado, R, Guàrdia, J, Guijarro, A, de Guindos, E, Hatzes, A P, Hauschildt, P H, Hedrosa, R P, Hermelo, I, Arabi, R Hernández, Otero, F Hernández, Hintz, D, Holgado, G, Huber, A

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Pharmacological modulation of the endocannabinoid system in a viral model of multiple sclerosis von Mestre, Leyre, Correa, Fernando, Arévalo‐Martín, Angel, Molina‐Holgado, Eduardo, Valenti, Marta, Ortar, Giorgio, Di Marzo, Vincenzo, Guaza, Carmen

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Activation of the endocannabinoid system as therapeutic approach in a murine model of multiple sclerosis von Ortega-Gutiérrez, Silvia, Molina-Holgado, Eduardo, Arévalo-Martín, Ángel, Correa, Fernando, Viso, Alma, López-Rodríguez, María L, Di Marzo, Vincenzo, Guaza, Carmen

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The endocannabinoid system modulates a transient TNF pathway that induces neural stem cell proliferation von Rubio-Araiz, Ana, Arévalo-Martín, Ángel, Gómez-Torres, Oscar, Navarro-Galve, Beatriz, García-Ovejero, Daniel, Suetterlin, Philipp, Sánchez-Heras, Elena, Molina-Holgado, Eduardo, Molina-Holgado, Francisco

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