Overcoming primary and acquired resistance to anti-PD-L1 therapy by induction and activation of tumor-residing cDC1s von Oba, Takaaki, Long, Mark D., Keler, Tibor, Marsh, Henry C., Minderman, Hans, Abrams, Scott I., Liu, Song, Ito, Fumito

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Development of a Novel Antibody-Drug Conjugate for the Potential Treatment of Ovarian, Lung, and Renal Cell Carcinoma Expressing TIM-1 von Thomas, Lawrence J, Vitale, Laura, O'Neill, Thomas, Dolnick, Ree Y, Wallace, Paul K, Minderman, Hans, Gergel, Lauren E, Forsberg, Eric M, Boyer, James M, Storey, James R, Pilsmaker, Catherine D, Hammond, Russell A, Widger, Jenifer, Sundarapandiyan, Karuna, Crocker, Andrea, Marsh, Jr, Henry C, Keler, Tibor

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Development of CDX-527: a bispecific antibody combining PD-1 blockade and CD27 costimulation for cancer immunotherapy von Vitale, Laura A., He, Li-Zhen, Thomas, Lawrence J., Wasiuk, Anna, O’Neill, Thomas, Widger, Jenifer, Crocker, Andrea, Mills-Chen, Laura, Forsberg, Eric, Weidlick, Jeffrey, Patterson, Colleen, Hammond, Russell A., Boyer, James, Sisson, Crystal, Alvarado, Diego, Goldstein, Joel, Marsh, Henry C., Keler, Tibor

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Development of CDX-1140, an agonist CD40 antibody for cancer immunotherapy von Vitale, Laura A., Thomas, Lawrence J., He, Li-Zhen, O’Neill, Thomas, Widger, Jenifer, Crocker, Andrea, Sundarapandiyan, Karuna, Storey, James R., Forsberg, Eric M., Weidlick, Jeffrey, Baronas, April R., Gergel, Lauren E., Boyer, James M., Sisson, Crystal, Goldstein, Joel, Marsh, Henry C., Keler, Tibor

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Complement activation is critical for placental ischemia-induced hypertension in the rat von Lillegard, Kathryn E., Johnson, Alex C., Lojovich, Sarah J., Bauer, Ashley J., Marsh, Henry C., Gilbert, Jeffrey S., Regal, Jean F.

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Toll-like receptor agonists shape the immune responses to a mannose receptor-targeted cancer vaccine von He, Li-Zhen, Weidlick, Jeffrey, Sisson, Crystal, Marsh, Henry C, Keler, Tibor

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A Critical Role of CD40 and CD70 Signaling in Conventional Type 1 Dendritic Cells in Expansion and Antitumor Efficacy of Adoptively Transferred Tumor-Specific T Cells von Oba, Takaaki, Hoki, Toshifumi, Yamauchi, Takayoshi, Keler, Tibor, Marsh, Henry C., Cao, Xuefang, Ito, Fumito

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CDX-585, a Bispecific Antibody with Dual Targeting of ILT4 and PD-1 Checkpoint Pathways von Murphy, Michael B., Vitale, Laura, Xia, Shukai, Peng, Zeyu, O’Neill, Thomas, Lillquist, Jay, Wasiuk, Anna, Weidlick, Jeff, Widger, Jenifer, Mills-Chen, Laura, Crocker, Andrea, Patterson, Colleen, Boyer, James, Baronas, April R., Chen, Mingjiu, Davis, Hugh M., Ma, Mark, Goldstein, Joel, Thomas, Lawrence J., Alvarado, Diego, Marsh, Henry C., Keler, Tibor

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Soluble human complement receptor 1 limits ischemic damage in cardiac surgery patients at high risk requiring cardiopulmonary bypass von LAZAR, Harold L, BOKESCH, Paula M, VAN LENTA, Frederick, FITZGERALD, Carmel, EMMETT, Constance, MARSH, Henry C, RYAN, Una

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Vaccine-Induced Antibodies Inhibit CETP Activity In Vivo and Reduce Aortic Lesions in a Rabbit Model of Atherosclerosis von Rittershaus, Charles W, Miller, David P, Thomas, Lawrence J, Picard, Michele D, Honan, Christopher M, Emmett, Constance D, Pettey, Carolyn L, Adari, Hedy, Hammond, Russell A, Beattie, David T, Callow, Allan D, Marsh, Henry C, Ryan, Una S

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Beneficial effects of complement inhibition with soluble complement receptor 1 (TP10) during cardiac surgery : Is there a gender difference? von LAZAR, Harold L, KEILANI, Taha, FITZGERALD, Carmel A, SHAPIRA, Oz M, HUNTER, Curtis T, SHEMIN, Richard J, MARSH, Henry C, RYAN, Una S

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CD27-Mediated Regulatory T Cell Depletion and Effector T Cell Costimulation Both Contribute to Antitumor Efficacy von Wasiuk, Anna, Testa, James, Weidlick, Jeff, Sisson, Crystal, Vitale, Laura, Widger, Jenifer, Crocker, Andrea, Thomas, Lawrence J, Goldstein, Joel, Marsh, Henry C, Keler, Tibor, He, Li-Zhen

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Conditioning treatment with CD27 Ab enhances expansion and antitumor activity of adoptively transferred T cells in mice von Wasiuk, Anna, Weidlick, Jeff, Sisson, Crystal, Widger, Jenifer, Crocker, Andrea, Vitale, Laura, Marsh, Henry C., Keler, Tibor, He, Li-Zhen

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The Partly Folded Back Solution Structure Arrangement of the 30 SCR Domains in Human Complement Receptor Type 1 (CR1) Permits Access to its C3b and C4b Ligands von Furtado, Patricia B., Huang, Chen Y., Ihyembe, Demvihin, Hammond, Russell A., Marsh, Henry C., Perkins, Stephen J.

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Characterization of the human T cell response to in vitro CD27 costimulation with varlilumab von Ramakrishna, Venky, Sundarapandiyan, Karuna, Zhao, Biwei, Bylesjo, Max, Marsh, Henry C, Keler, Tibor

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Soluble CR1 Therapy Improves Complement Regulation in C3 Glomerulopathy von YUZHOU ZHANG, NESTER, Carla M, HOLANDA, Danniele G, MARSH, Henry C, HAMMOND, Russell A, THOMAS, Lawrence J, MEYER, Nicole C, HUNSICKER, Lawrence G, SETHI, Sanjeev, SMITH, Richard J. H

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Soluble Human Complement Receptor Type 1: In Vivo Inhibitor of Complement Suppressing Post-Ischemic Myocardial Inflammation and Necrosis von Weisman, Harlan F., Bartow, Thomas, Leppo, Michelle K., Marsh, Henry C., Carson, Gerald R., Concino, Michael F., Boyle, Michael P., Roux, Kenneth H., Weisfeldt, Myron L., Fearon, Douglas T.

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Abstract 4866: Development and characterization of novel CD40 antibody agonists for cancer immunotherapy von Vitale, Laura A., O’Neill, Thomas, Widger, Jenifer, Crocker, Andrea, He, Li-Zhen, Weidlick, Jeffrey, Sundarapandiyan, Karuna, Storey, James, Thomas, Lawrence, Goldstein, Joel, Marsh, Henry C., Keler, Tibor

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Preclinical evaluation of the neuroprotective effect of soluble complement receptor Type 1 in a nonhuman primate model of reperfused stroke von MOCCO, J, MACK, William J, PINSKY, David J, CONNOLLY, E. Sander, DUCRUET, Andrew F, KING, Ryan G, SUGHRUE, Michael E, COON, Alexander L, SOSUNOV, Sergei A, SCIACCA, Robert R, YUAN ZHANG, MARSH, Henry C

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Comparison of Complement Activity in Adult and Preterm Sheep Serum von Ahmed, Shatha, Kemp, Matthew W., Payne, Matthew S., Kallapur, Suhas G., Stock, Sarah J., Marsh, Henry C., Jobe, Alan H., Newnham, John P., Spiller, Owen B.

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