De Novo Design of Nurr1 Agonists via Fragment-Augmented Generative Deep Learning in Low-Data Regime von Ballarotto, Marco, Willems, Sabine, Stiller, Tanja, Nawa, Felix, Marschner, Julian A., Grisoni, Francesca, Merk, Daniel

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Extracellular traps in kidney disease von Nakazawa, Daigo, Marschner, Julian A., Platen, Louise, Anders, Hans-Joachim

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The macrophage phenotype and inflammasome component NLRP3 contributes to nephrocalcinosis-related chronic kidney disease independent from IL-1–mediated tissue injury von Anders, Hans-Joachim, Suarez-Alvarez, Beatriz, Grigorescu, Melissa, Foresto-Neto, Orestes, Steiger, Stefanie, Desai, Jyaysi, Marschner, Julian A., Honarpisheh, Mohsen, Shi, Chongxu, Jordan, Jutta, Müller, Lisa, Burzlaff, Nicolai, Bäuerle, Tobias, Mulay, Shrikant R.

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Tubular Epithelial Cell HMGB1 Promotes AKI-CKD Transition by Sensitizing Cycling Tubular Cells to Oxidative Stress: A Rationale for Targeting HMGB1 during AKI Recovery von Zhao, Zhi Bo, Marschner, Julian A, Iwakura, Takamasa, Li, Chenyu, Motrapu, Manga, Kuang, Meisi, Popper, Bastian, Linkermann, Andreas, Klocke, Jan, Enghard, Philipp, Muto, Yoshiharu, Humphreys, Benjamin D, Harris, Helena Erlandsson, Romagnani, Paola, Anders, Hans-Joachim

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Endocycle-related tubular cell hypertrophy and progenitor proliferation recover renal function after acute kidney injury von Lazzeri, Elena, Angelotti, Maria Lucia, Peired, Anna, Conte, Carolina, Marschner, Julian A., Maggi, Laura, Mazzinghi, Benedetta, Lombardi, Duccio, Melica, Maria Elena, Nardi, Sara, Ronconi, Elisa, Sisti, Alessandro, Antonelli, Giulia, Becherucci, Francesca, De Chiara, Letizia, Guevara, Ricardo Romero, Burger, Alexa, Schaefer, Beat, Annunziato, Francesco, Anders, Hans-Joachim, Lasagni, Laura, Romagnani, Paola

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Intestinal Dysbiosis, Barrier Dysfunction, and Bacterial Translocation Account for CKD-Related Systemic Inflammation von Andersen, Kirstin, Kesper, Marie Sophie, Marschner, Julian A, Konrad, Lukas, Ryu, Mi, Kumar Vr, Santhosh, Kulkarni, Onkar P, Mulay, Shrikant R, Romoli, Simone, Demleitner, Jana, Schiller, Patrick, Dietrich, Alexander, Müller, Susanna, Gross, Oliver, Ruscheweyh, Hans-Joachim, Huson, Daniel H, Stecher, Bärbel, Anders, Hans-Joachim

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Mitochondria Permeability Transition versus Necroptosis in Oxalate-Induced AKI von Mulay, Shrikant Ramesh, Honarpisheh, Mohsen M, Foresto-Neto, Orestes, Shi, Chongxu, Desai, Jyaysi, Zhao, Zhi Bo, Marschner, Julian A, Popper, Bastian, Buhl, Ewa Miriam, Boor, Peter, Linkermann, Andreas, Liapis, Helen, Bilyy, Rostyslav, Herrmann, Martin, Romagnani, Paola, Belevich, Ilya, Jokitalo, Eija, Becker, Jan U, Anders, Hans-Joachim

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Dipeptidyl peptidase-4 inhibitor teneligliptin accelerates recovery from cisplatin-induced acute kidney injury by attenuating inflammation and promoting tubular regeneration von Iwakura, Takamasa, Zhao, Zhibo, Marschner, Julian A, Devarapu, Satish Kumar, Yasuda, Hideo, Anders, Hans Joachim

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Development of Tailless Homologue Receptor (TLX) Agonist Chemical Tools von Hank, Emily C., Sai, Minh, Kasch, Till, Meijer, Isabelle, Marschner, Julian A., Merk, Daniel

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Optimizing Mouse Surgery with Online Rectal Temperature Monitoring and Preoperative Heat Supply. Effects on Post-Ischemic Acute Kidney Injury von Marschner, Julian A, Schäfer, Hannah, Holderied, Alexander, Anders, Hans-Joachim

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Histones and Neutrophil Extracellular Traps Enhance Tubular Necrosis and Remote Organ Injury in Ischemic AKI von Nakazawa, Daigo, Kumar, Santhosh V, Marschner, Julian, Desai, Jyaysi, Holderied, Alexander, Rath, Lukas, Kraft, Franziska, Lei, Yutian, Fukasawa, Yuichiro, Moeckel, Gilbert W, Angelotti, Maria Lucia, Liapis, Helen, Anders, Hans-Joachim

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Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury von Tonnus, Wulf, Meyer, Claudia, Steinebach, Christian, Belavgeni, Alexia, von Mässenhausen, Anne, Gonzalez, Nadia Zamora, Maremonti, Francesca, Gembardt, Florian, Himmerkus, Nina, Latk, Markus, Locke, Sophie, Marschner, Julian, Li, Wenjun, Short, Spencer, Doll, Sebastian, Ingold, Irina, Proneth, Bettina, Daniel, Christoph, Kabgani, Nazanin, Kramann, Rafael, Motika, Stephen, Hergenrother, Paul J., Bornstein, Stefan R., Hugo, Christian, Becker, Jan Ulrich, Amann, Kerstin, Anders, Hans-Joachim, Kreisel, Daniel, Pratt, Derek, Gütschow, Michael, Conrad, Marcus, Linkermann, Andreas

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Chemogenomics for NR1 nuclear hormone receptors von Isigkeit, Laura, Schallmayer, Espen, Busch, Romy, Brunello, Lorene, Menge, Amelie, Elson, Lewis, Müller, Susanne, Knapp, Stefan, Stolz, Alexandra, Marschner, Julian A., Merk, Daniel

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A High‐Quality Photoswitchable Probe that Selectively and Potently Regulates the Transcription Factor RORγ von Reynders, Martin, Willems, Sabine, Marschner, Julian A., Wein, Thomas, Merk, Daniel, Thorn‐Seshold, Oliver

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A Nurr1 Agonist Derived from the Natural Ligand DHI Induces Neuroprotective Gene Expression von Egner, Markus, Busch, Romy, López-García, Úrsula, Lewandowski, Max, Höfner, Georg, Wein, Thomas, Marschner, Julian A, Merk, Daniel

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The Kidney Contains Ontogenetically Distinct Dendritic Cell and Macrophage Subtypes throughout Development That Differ in Their Inflammatory Properties von Salei, Natallia, Rambichler, Stephan, Salvermoser, Johanna, Papaioannou, Nikos E, Schuchert, Ronja, Pakalniškytė, Dalia, Li, Na, Marschner, Julian A, Lichtnekert, Julia, Stremmel, Christopher, Cernilogar, Filippo M, Salvermoser, Melanie, Walzog, Barbara, Straub, Tobias, Schotta, Gunnar, Anders, Hans-Joachim, Schulz, Christian, Schraml, Barbara U

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Development of a Potent Nurr1 Agonist Tool for In Vivo Applications von Vietor, Jan, Gege, Christian, Stiller, Tanja, Busch, Romy, Schallmayer, Espen, Kohlhof, Hella, Höfner, Georg, Pabel, Jörg, Marschner, Julian A., Merk, Daniel

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Regulated necrosis-related molecule mRNA expression in humans and mice and in murine acute tissue injury and systemic autoimmunity leading to progressive organ damage, and progress... von Honarpisheh, Mohsen, Desai, Jyaysi, Marschner, Julian A, Weidenbusch, Marc, Lech, Maciej, Vielhauer, Volker, Anders, Hans-Joachim, Mulay, Shrikant R

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Druggability Evaluation of the Neuron Derived Orphan Receptor (NOR‐1) Reveals Inverse NOR‐1 Agonists von Zaienne, Daniel, Arifi, Silvia, Marschner, Julian A., Heering, Jan, Merk, Daniel

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Rational Design of a New RXR Agonist Scaffold Enabling Single-Subtype Preference for RXRα, RXRβ, and RXRγ von Adouvi, Gustave, Isigkeit, Laura, López-García, Úrsula, Chaikuad, Apirat, Marschner, Julian A., Schubert-Zsilavecz, Manfred, Merk, Daniel

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