Broad-Spectrum Antiviral Activity of the IMP Dehydrogenase Inhibitor VX-497: a Comparison with Ribavirin and Demonstration of Antiviral Additivity with Alpha Interferon von MARKLAND, W, MCQUAID, T. J, JAIN, J, KWONG, A. D

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Crystal Structure of the Hepatitis C Virus NS3 Protease Domain Complexed with a Synthetic NS4A Cofactor Peptide von Kim, J.L, Morgenstern, K.A, Lin, C, Fox, T, Dwyer, M.D, Landro, J.A, Chambers, S.P, Markland, W, Lepre, C.A, O'Malley, E.T, Harbeson, S.L, Rice, C.M, Murcko, M.A, Caron, P.R, Thomson, J.A

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M13 bacteriophage displaying disulfide-constrained microproteins von McLafferty, M.A., Kent, R.B., Ladner, R.C., Markland, W.

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Directed Evolution of a Protein: Selection of Potent Neutrophil Elastase Inhibitors Displayed on M13 Fusion Phage von Roberts, Bruce L., Markland, William, Ley, Arthur C., Kent, Rachel B., White, David W., Ladner, Robert charles

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Structural and Kinetic Analyses of the Protease from an Amprenavir-Resistant Human Immunodeficiency Virus Type 1 Mutant Rendered Resistant to Saquinavir and Resensitized to Amprena... von Markland, W, Rao, B G, Parsons, J D, Black, J, Zuchowski, L, Tisdale, M, Tung, R

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Preclinical characterization of the selective DNA-dependent protein kinase (DNA-PK) inhibitor VX-984 in combination with chemotherapy von Boucher, D., Hillier, S., Newsome, D., Wang, Y., Takemoto, D., Gu, Y., Markland, W., Hoover, R., Arimoto, R., Maxwell, J., Fields, S.Z., Charifson, P., Penney, M.S., Tanner, K.

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Crystal structure of JNK3: a kinase implicated in neuronal apoptosis von Xie, Xiaoling, Gu, Yong, Fox, Ted, Coll, Joyce T, Fleming, Mark A, Markland, William, Caron, Paul R, Wilson, Keith P, Su, Michael S-S

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Active-Site Residues of Escherichia coli DNA Gyrase Required in Coupling ATP Hydrolysis to DNA Supercoiling and Amino Acid Substitutions Leading to Novobiocin Resistance von GROSS, Christian H, PARSONS, Jonathan D, RAYBUCK, Scott A, GROSSMAN, Trudy H, CHARIFSON, Paul S, BELLON, Steven, JERNEE, James, DWYER, Maureen, CHAMBERS, Stephen P, MARKLAND, William, BOTFIELD, Martyn

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[2] Selection for protease inhibitors using bacteriophage display von Markland, William, Roberts, Bruce L., Ladner, Robert C.

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Design, construction and function of a multicopy display vector using fusions to the major coat protein of bacteriophage M13 von Markland, W., Roberts, B.L., Saxena, M.J., Guterman, S.K., Ladner, R.C.

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[4] Affinity maturation of proteins displayed on surface of M13 bacteriophage as major coat protein fusions von Roberts, Bruce L., Markland, William, Ladner, Robert C.

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Signal-dependent translocation of simian virus 40 large-T antigen into rat liver nuclei in a cell-free system von MARKLAND, W, SMITH, A. E, ROBERTS, B. L

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Protease inhibitor display M13 phage: selection of high-affinity neutrophil elastase inhibitors von Roberts, B.L., Markland, W., Siranosian, K., Saxena, M.J., Guterman, S.K., Ladner, R.C.

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Iterative Optimization of High-Affinity Protease Inhibitors Using Phage Display. 2. Plasma Kallikrein and Thrombin von Markland, William, Ley, Arthur Charles, Ladner, Robert Charles

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Iterative Optimization of High-Affinity Protease Inhibitors Using Phage Display. 1. Plasmin von Markland, William, Ley, Arthur Charles, Lee, Stanley W, Ladner, Robert Charles

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Site-directed mutagenesis of polyomavirus middle-T antigen sequences encoding tyrosine 315 and tyrosine 250 von MARKLAND, W, OOSTRA, B. A, HARVEY, R, MARKHAM, A. F, COLLEDGE, W. H, SMITH, A. E

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Association of p62c-yes with polyomavirus middle T-antigen mutants correlates with transforming ability von KORNBLUTH, S, CHENG, S. H, MARKLAND, W, FUKUI, Y, HANAFUSA, H

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Mapping of the amino-terminal half of polyomavirus middle-T antigen indicates that this region is the binding domain for pp60c-src von MARKLAND, W, SMITH, A. E

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In vitro mutagenesis of the putative membrane-binding domain of polyomavirus middle-T antigen von MARKLAND, W, CHENG, S. H, OOSTRA, B. A, SMITH, A. E

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Mutations around the NG59 lesion indicate an active association of polyoma virus middle‐T antigen with pp60c‐src is required for cell transformation von Cheng, S.H., Markland, W., Markham, A.F., Smith, A.E.

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