Substituted piperidines - highly potent renin inhibitors due to induced fit adaptation of the active site von Vieira, Eric, Binggeli, Alfred, Breu, Volker, Bur, Daniel, Fischli, Walter, Güller, Rolf, Hirth, Georges, Märki, Hans Peter, Müller, Marcel, Oefner, Christian, Scalone, Michelangelo, Stadler, Heinz, Wihelm, Maurice, Wostl, Wolfgang

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A Novel Partial Agonist of Peroxisome Proliferator-Activated Receptor-γ (PPARγ) Recruits PPARγ-Coactivator-1α, Prevents Triglyceride Accumulation, and Potentiates Insulin Signaling... von Burgermeister, Elke, Schnoebelen, Astride, Flament, Angele, Benz, Jörg, Stihle, Martine, Gsell, Bernard, Rufer, Arne, Ruf, Armin, Kuhn, Bernd, Märki, Hans Peter, Mizrahi, Jacques, Sebokova, Elena, Niesor, Eric, Meyer, Markus

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Piperidine-renin inhibitors compounds with improved physicochemical properties von Güller, Rolf, Binggeli, Alfred, Breu, Volker, Bur, Daniel, Fischli, Walter, Hirth, Georges, Jenny, Christian, Kansy, Manfred, Montavon, François, Müller, Marcel, Oefner, Christian, Stadler, Heinz, Vieira, Eric, Wilhelm, Maurice, Wostl, Wolfgang, Märki, Hans Peter

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Grain growth of differently doped zirconia von Allemann, J.A., Michel, B., Märki, H.-B., Gauckler, L.J., Moser, E.M.

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Identification of the active-site serine in human pancreatic lipase by chemical modification with tetrahydrolipstatin von QIAOQIAN LÜTHI-PENG, MÄRKI, H. P, HADVARY, P

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Piperidine renin inhibitors: from leads to drug candidates von Märki, H.P., Binggeli, A., Bittner, B., Bohner-Lang, V., Breu, V., Bur, D., Coassolo, Ph, Clozel, J.P., D'Arcy, A., Doebeli, H., Fischli 1, W., Funk, Ch, Foricher, J., Giller, T., Grüninger, F., Guenzi, A., Güller, R., Hartung, T., Hirth, G., Jenny, Ch, Kansy, M., Klinkhammer, U., Lave, T., Lohri, B., Luft, F.C., Mervaala, E.M., Müller, D.N., Müller, M., Montavon, F., Oefner, Ch, Qiu, C., Reichel, A., Sanwald-Ducray, P., Scalone, M., Schleimer, M., Schmid, R., Stadler, H., Treiber 1, A., Valdenaire 2, O., Vieira, E., Waldmeier, P., Wiegand-Chou, R., Wilhelm, M., Wostl, W., Zell, M., Zell, R.

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De Novo Design, Synthesis, and In Vitro Evaluation of a New Class of Nonpeptidic Inhibitors of the Malarial Enzyme Plasmepsin II von Carcache, David A., Hörtner, Simone R., Bertogg, Andreas, Binkert, Christoph, Bur, Daniel, Märki, Hans Peter, Dorn, Arnulf, Diederich, François

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Development of a New Class of Inhibitors for the Malarial Aspartic Protease Plasmepsin II Based on a Central 7-Azabicyclo[2.2.1]heptane Scaffold von Carcache, David A., Hörtner, Simone R., Seiler, Paul, Diederich, François, Dorn, Arnulf, Märki, Hans Peter, Binkert, Christoph, Bur, Daniel

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A New Class of Inhibitors for the Malarial Aspartic Protease Plasmepsin II Based on a Central 11-Azatricyclo[6.2.1.02,7]undeca-2,4,6-triene Scaffold von Carcache, David A., Hörtner, Simone R., Bertogg, Andreas, Diederich, François, Dorn, Arnulf, Märki, Hans Peter, Binkert, Christoph, Bur, Daniel

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Optically Pure Isoproterenol Analogues With Side Chains Containing an Amide Bond: Synthesis and biological properties von Märki, Hans P., Crameri, Yvo, Eigenmann, Rainer, Krasso, Anna, Ramuz, Henri, Bernauer, Karl, Goodman, Murray, Melmon, Kenneth L.

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Dr. Emilio Kyburz-Haerdi 26 February 1928 – 20 July 2005 von Imhof, René, Märki, Hans Peter, Froestl, Wolfgang, Hunkeler, Walter

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Renin inhibition by substituted piperidines: A novel paradigm for the inhibition of monomeric aspartic proteinases? von Oefner, C, Binggeli, A, Breu, V, Bur, D, Clozel, J-P, D'Arcy, A, Dorn, A, Fischli, W, Grüninger, F, Güller, R, Hirth, G, Märki, HP, Mathews, S, Müller, M, Ridley, RG, Stadier, H, Vieira, E, Wilhelm, M, Winkler, FK, Wostl, W

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Improvement of a mammalian cell culture process by adaptive, model-based dialysis fed-batch cultivation and suppression of apoptosis von FRAHM, B, LANE, P, MÄRKI, H, PÖRTNER, R

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Oxidosqualene Cyclase (OSC) Inhibitors for the Treatment of Dyslipidemia von Dehmlow, Henrietta, Thoma, Ralf, Ruf, Armin, Panday, Narendra, Von Der Mark, Elisabeth, Morand, Olivier, Märki, Hans Peter, Kansy, Manfred, Hartman, Peter, Coassolo, Philippe, Chucholowski, Alexander, Blum-Kaelin, Denise, Aebi, Johannes, Ackermann, Jean, Schulz-Gasch, Tanja

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EVAPORATOR von H. MARKI, J. GRUTER

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Acyclic stereoselection. XLIII: Stereoselective synthesis of the C-8 to C-15 moiety of erythronolide A von HOAGLAND, S, MORITA, Y, DONG LU BAI, MARKI, H.-P, KEES, K, BROWN, L, HEATHCOCK, C. H

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Acyclic stereoselection. 23. Lactaldehyde enolate equivalents von Heathcock, Clayton H, Pirrung, Michael C, Young, Steven D, Hagen, James P, Jarvi, Esa T, Badertscher, Ulrich, Marki, Hans Peter, Montgomery, Stephen H

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new type of water vibration receptor on the crayfish antenna. II. Model of receptor function von Masters, W.M, Aicher, B, Tautz, J, Marki, H

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Acyclic stereoselection. XXIII: Lactaldehyde enolate equivalents von HEATHCOCK, C. H, PIRRUNG, M. C, YOUNG, S. D, HAGEN, J. P, JARVI, E. T, BADERTSCHER, U, MARKI, H.-P, MONTGOMERY, S. H

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ChemInform Abstract: From Glycosaminoglycans to Heparinoid Mimetics with Antiproliferative Activity von Wessel, H. P., Chucholowski, A., Fingerle, J., Iberg, N., Marki, H. P., Muller, R., Pech, M., Pfister-Downar, M., Rouge, M., Schmid, G., ., et al

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