MLi-2, a Potent, Selective, and Centrally Active Compound for Exploring the Therapeutic Potential and Safety of LRRK2 Kinase Inhibition von Fell, Matthew J, Mirescu, Christian, Basu, Kallol, Cheewatrakoolpong, Boonlert, DeMong, Duane E, Ellis, J Michael, Hyde, Lynn A, Lin, Yinghui, Markgraf, Carrie G, Mei, Hong, Miller, Michael, Poulet, Frederique M, Scott, Jack D, Smith, Michelle D, Yin, Zhizhang, Zhou, Xiaoping, Parker, Eric M, Kennedy, Matthew E, Morrow, John A

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Characterization of the Onset, Progression, and Reversibility of Morphological Changes in Mouse Lung after Pharmacological Inhibition of Leucine-Rich Kinase 2 Kinase Activity von Bryce, Dianne K., Ware, Chris M., Woodhouse, Janice D., Ciaccio, Paul J., Ellis, J. Michael, Hegde, Laxminarayan G., Kuruvilla, Sabu, Maddess, Matthew L., Markgraf, Carrie G., Otte, Karin M., Poulet, Frederique M., Timmins, Lauren M., Kennedy, Matthew E., Fell, Matthew J.

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Six-hour window of opportunity for calpain inhibition in focal cerebral ischemia in rats von Markgraf, C G, Velayo, N L, Johnson, M P, McCarty, D R, Medhi, S, Koehl, J R, Chmielewski, P A, Linnik, M D

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Twenty years of safety pharmacology model validation and the wider implications of this to drug discovery von Pugsley, Michael K., Bekele, Bisrat, Griessel, Helene, de Korte, Tessa, Authier, Simon, Grobler, Anne F., Markgraf, Carrie G., Curtis, Michael J.

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Abuse liability assessment for biologic drugs – All molecules are not created equal von de Zafra, Christina L. Zuch, Markgraf, Carrie G., Compton, David R., Hudzik, Thomas J.

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Assessment of seizure liability of Org 306039, a 5-HT2c agonist, using hippocampal brain slice and rodent EEG telemetry von Markgraf, Carrie G., DeBoer, Erik, Zhai, Jin, Cornelius, Lara, Zhou, Ying Ying, MacSweeney, Cliona

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Comparison of methods for analysis of functional observation battery (FOB) data von Markgraf, Carrie G., Cirino, Maria, Meredith, John

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The Safety Pharmacology Society salary survey von Pugsley, Michael K., Authier, Simon, Brabham, Tiffini, Soloviev, Maxim, Markgraf, Carrie G., Correll, Krystle, Traebert, Martin, Greiter-Wilke, Andrea, Valentin, Jean-Pierre, Vargas, Hugo, Botchway, Alfred, Leishman, Derek J., Curtis, Michael J.

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Validation of a motor activity system by a robotically controlled vehicle and using standard reference compounds von Patterson, John P., Markgraf, Carrie G., Cirino, Maria, Bass, Alan S.

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Sensorimotor and cognitive consequences of middle cerebral artery occlusion in rats von Markgraf, Carrie G., Green, Edward J., Hurwitz, Barry E., Morikawa, Eiharu, Dalton Dietrich, W., McCabe, Philip M., Ginsberg, Myron D., Schneiderman, Neil

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Injury severity and sensitivity to treatment after controlled cortical impact in rats von MARKGRAF, Carrie G, CLIFTON, Guy L, AGUIRRE, Michela, CHANEY, Stephan F, KNOX-DU BOIS, Cami, KENNON, Katherine, VERMA, Nishi

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Recovery of sensorimotor function after distal middle cerebral artery photothrombotic occlusion in rats von Markgraf, C G, Green, E J, Watson, B, McCabe, P M, Schneiderman, N, Dietrich, W D, Ginsberg, M D

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An Overview of the Safety Pharmacology Society (SPS) Strategic Plan (2016-2018) von Pugsley, Michael K., Authier, Simon, Koerner, John, Redfern, Will S., Markgraf, Carrie G., Brabham, Tiffini, Correll, Krystle, Soloviev, Maxim, Botchway, Alfred, Engwall, Michael, Traebert, Martin, Valentin, Jean-Pierre, Mow, Tomas, Greiter-Wilke, Andrea, Prior, Helen, Vargas, Hugo M., Leishman, Derek J.

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Assessment of seizure liability of Org 306039, a 5-HT sub(2c) agonist, using hippocampal brain slice and rodent EEG telemetry von Markgraf, Carrie G, DeBoer, Erik, Zhai, Jin, Cornelius, Lara, Zhou, Ying Ying, MacSweeney, Cliona

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Overview of the joint PhRMA-FDA dialogue session on abuse potential assessment von Markgraf, Carrie G., Kallman, Mary Jeanne

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EEG in monkey but not rat indentifies seizure potential of a pharmaceutical development candidate von Markgraf, Carrie G., DeBoer, Erik M., Cirino, Maria

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Behavioral Recovery Patterns in Rats Receiving the NMDA Receptor Antagonist MDL 100,453 Immediately Post-Stroke von Markgraf, Carrie G, Johnson, Michael P, Braun, Don L, Bickers, Mary V

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MDL 101,002, a free radical spin trap, is efficacious in permanent and transient focal ischemia models von Johnson, Michael P, McCarty, Debbie R, Velayo, Nelson L, Markgraf, Carrie G, Chmielewski, Paula A, Ficorilli, James V, Cheng, Hsien C, Thomas, Craig E

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Comparative histopathologic consequences of photothrombotic occlusion of the distal middle cerebral artery in Sprague-Dawley and wistar rats von MARKGRAF, C. G, KRAYDIEH, S, PRADO, R, WATSON, B. D, DALTON DIETRICH, W, GINSBERG, M. D, GARCIA, J. H

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Glutamate antagonist MK-801 attenuates incomplete but not complete infarction in thrombotic distal middle cerebral artery occlusion in Wistar rats von Yao, Hiroshi, Markgraf, Carrie G., Dietrich, W. Dalton, Prado, Ricardo, Watson, Brant D., Ginsberg, Myron D.

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