Optimizing Timing of Immunotherapy Improves Control of Tumors by Hypofractionated Radiation Therapy von Young, Kristina H, Baird, Jason R, Savage, Talicia, Cottam, Benjamin, Friedman, David, Bambina, Shelly, Messenheimer, David J, Fox, Bernard, Newell, Pippa, Bahjat, Keith S, Gough, Michael J, Crittenden, Marka R

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The paradox of radiation and T cells in tumors von Gough, Michael J., Crittenden, Marka R.

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TGFβ suppresses CD8+ T cell expression of CXCR3 and tumor trafficking von Gunderson, Andrew J., Yamazaki, Tomoko, McCarty, Kayla, Fox, Nathaniel, Phillips, Michaela, Alice, Alejandro, Blair, Tiffany, Whiteford, Mark, O’Brien, David, Ahmad, Rehan, Kiely, Maria X., Hayman, Amanda, Crocenzi, Todd, Gough, Michael J., Crittenden, Marka R., Young, Kristina H.

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Role of the immunosuppressive microenvironment in immunotherapy von Tormoen, Garth W., MD, PhD, Crittenden, Marka R., MD, PhD, Gough, Michael J., PhD

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Expression of NF-κB p50 in tumor stroma limits the control of tumors by radiation therapy von Crittenden, Marka R, Cottam, Benjamin, Savage, Talicia, Nguyen, Cynthia, Newell, Pippa, Gough, Michael J

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Tumor cure by radiation therapy and checkpoint inhibitors depends on pre-existing immunity von Crittenden, Marka R., Zebertavage, Lauren, Kramer, Gwen, Bambina, Shelly, Friedman, David, Troesch, Victoria, Blair, Tiffany, Baird, Jason R., Alice, Alejandro, Gough, Michael J.

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Tumor resident memory CD8 T cells and concomitant tumor immunity develop independently of CD4 help von Medler, Terry R., Kramer, Gwen, Bambina, Shelly, Gunderson, Andrew J., Alice, Alejandro, Blair, Tiffany, Zebertavage, Lauren, Duhen, Thomas, Duhen, Rebekka, Young, Kristina, Crittenden, Marka R., Gough, Michael J.

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Transcriptional Upregulation of NLRC5 by Radiation Drives STING- and Interferon-Independent MHC-I Expression on Cancer Cells and T Cell Cytotoxicity von Zebertavage, Lauren K., Alice, Alejandro, Crittenden, Marka R., Gough, Michael J.

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Radiotherapy Combined with Novel STING-Targeting Oligonucleotides Results in Regression of Established Tumors von Baird, Jason R, Friedman, David, Cottam, Benjamin, Dubensky, Jr, Thomas W, Kanne, David B, Bambina, Shelly, Bahjat, Keith, Crittenden, Marka R, Gough, Michael J

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Transcriptional and immunohistological assessment of immune infiltration in pancreatic cancer von Bernard, Brady, Rajamanickam, Venkatesh, Dubay, Christopher, Piening, Brian, Alonso, Emilio, Jutric, Zeljka, Tang, Ephraim, Newell, Pippa, Hansen, Paul, Medler, Terry, Gunderson, Andrew, Young, Kristina, Bifulco, Carlo, Pucliowska, Joanna, Crittenden, Marka R, Gough, Michael J

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Dendritic Cell Maturation Defines Immunological Responsiveness of Tumors to Radiation Therapy von Blair, Tiffany C, Bambina, Shelly, Alice, Alejandro F, Kramer, Gwen F, Medler, Terry R, Baird, Jason R, Broz, Miranda L, Tormoen, Garth W, Troesch, Victoria, Crittenden, Marka R, Gough, Michael J

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Current Clinical Trials Testing Combinations of Immunotherapy and Radiation von Crittenden, Marka, MD, PhD, Kohrt, Holbrook, MD, Levy, Ronald, MD, Jones, Jennifer, MD, PhD, Camphausen, Kevin, MD, Dicker, Adam, MD, PhD, Demaria, Sandra, MD, Formenti, Silvia, MD

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Blockade of fibroblast activation protein in combination with radiation treatment in murine models of pancreatic adenocarcinoma von Gunderson, Andrew J, Yamazaki, Tomoko, McCarty, Kayla, Phillips, Michaela, Alice, Alejandro, Bambina, Shelly, Zebertavage, Lauren, Friedman, David, Cottam, Benjamin, Newell, Pippa, Gough, Michael J, Crittenden, Marka R, Van der Veken, Pieter, Young, Kristina H

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Galunisertib plus neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer: a single-arm, phase 2 trial von Yamazaki, Tomoko, Gunderson, Andrew J, Gilchrist, Miranda, Whiteford, Mark, Kiely, Maria X, Hayman, Amanda, O'Brien, David, Ahmad, Rehan, Manchio, Jeffrey V, Fox, Nathaniel, McCarty, Kayla, Phillips, Michaela, Brosnan, Evelyn, Vaccaro, Gina, Li, Rui, Simon, Miklos, Bernstein, Eric, McCormick, Mary, Yamasaki, Lena, Wu, Yaping, Drokin, Ashley, Carnahan, Trevor, To, Yy, Redmond, William L, Lee, Brian, Louie, Jeannie, Hansen, Eric, Solhjem, Matthew C, Cramer, Julie, Urba, Walter J, Gough, Michael J, Crittenden, Marka R, Young, Kristina H

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Programmed cell death‐1 blockade enhances response to stereotactic radiation in an orthotopic murine model of hepatocellular carcinoma von Friedman, David, Baird, Jason R., Young, Kristina H., Cottam, Benjamin, Crittenden, Marka R., Friedman, Scott, Gough, Michael J., Newell, Pippa

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Moving beyond the T cell synapse for combination neoadjuvant immunotherapy in head and neck cancer von Bell, R. Bryan, Gough, Michael, Crittenden, Marka, Young, Kristina

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Defining Immunogenic and Radioimmunogenic Tumors von Medler, Terry R, Blair, Tiffany C, Crittenden, Marka R, Gough, Michael J

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ICOS is upregulated on T cells following radiation and agonism combined with radiation results in enhanced tumor control von Blair, Tiffany, Baird, Jason, Bambina, Shelly, Kramer, Gwen, Gostissa, Monica, Harvey, Christopher J., Gough, Michael J., Crittenden, Marka R.

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Myeloid MyD88 restricts CD8+ T cell response to radiation therapy in pancreatic cancer von Medler, Terry R., Blair, Tiffany C., Alice, Alejandro F., Dowdell, Alexa K., Piening, Brian D., Crittenden, Marka R., Gough, Michael J.

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Stimulating innate immunity to enhance radiation therapy-induced tumor control von Baird, Jason R., PhD, Monjazeb, Arta M., MD PhD, Shah, Omid, MD, McGee, Heather, MD PhD, Murphy, William J., PhD, Crittenden, Marka R., MD PhD, Gough, Michael J., PhD

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