Oxetanes as Versatile Elements in Drug Discovery and Synthesis von Burkhard, Johannes A., Wuitschik, Georg, Rogers-Evans, Mark, Müller, Klaus, Carreira, Erick M.

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NF‐κB activation in astrocytes drives a stage‐specific beneficial neuroimmunological response in ALS von Ouali Alami, Najwa, Schurr, Christine, Olde Heuvel, Florian, Tang, Linyun, Li, Qian, Tasdogan, Alpaslan, Kimbara, Atsushi, Nettekoven, Matthias, Ottaviani, Giorgio, Raposo, Catarina, Röver, Stephan, Rogers‐Evans, Mark, Rothenhäusler, Benno, Ullmer, Christoph, Fingerle, Jürgen, Grether, Uwe, Knuesel, Irene, Boeckers, Tobias M, Ludolph, Albert, Wirth, Thomas, Roselli, Francesco, Baumann, Bernd

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Oxetanes as Promising Modules in Drug Discovery von Wuitschik, Georg, Rogers-Evans, Mark, Müller, Klaus, Fischer, Holger, Wagner, Björn, Schuler, Franz, Polonchuk, Liudmila, Carreira, Erick M.

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Construction of Multifunctional Modules for Drug Discovery: Synthesis of Novel Thia/Oxa-Azaspiro[3.4]octanes von Li, Dong Bo, Rogers-Evans, Mark, Carreira, Erick M

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Synthesis and Stability of Oxetane Analogs of Thalidomide and Lenalidomide von Burkhard, Johannes A, Wuitschik, Georg, Plancher, Jean-Marc, Rogers-Evans, Mark, Carreira, Erick M

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Synthesis and Structural Analysis of a New Class of Azaspiro[3.3]heptanes as Building Blocks for Medicinal Chemistry von Burkhard, Johannes A., Guérot, Carine, Knust, Henner, Rogers-Evans, Mark, Carreira, Erick M.

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Spirocyclic Oxetanes: Synthesis and Properties von Wuitschik, Georg, Rogers-Evans, Mark, Buckl, Andreas, Bernasconi, Maurizio, Märki, Moritz, Godel, Thierry, Fischer, Holger, Wagner, Björn, Parrilla, Isabelle, Schuler, Franz, Schneider, Josef, Alker, André, Schweizer, W. Bernd, Müller, Klaus, Carreira, Erick M.

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Discovery of Highly Selective Brain-Penetrant Vasopressin 1a Antagonists for the Potential Treatment of Autism via a Chemogenomic and Scaffold Hopping Approach von Ratni, Hasane, Rogers-Evans, Mark, Bissantz, Caterina, Grundschober, Christophe, Moreau, Jean-Luc, Schuler, Franz, Fischer, Holger, Alvarez Sanchez, Ruben, Schnider, Patrick

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Synthesis of Novel Azaspiro[3.4]octanes as Multifunctional Modules in Drug Discovery von Li, Dong Bo, Rogers-Evans, Mark, Carreira, Erick M

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Selective Cannabinoid 2 Receptor Agonists as Potential Therapeutic Drugs for the Treatment of Endotoxin-Induced Uveitis von Porter, Richard Frederick, Szczesniak, Anna-Maria, Toguri, James Thomas, Gebremeskel, Simon, Johnston, Brent, Lehmann, Christian, Fingerle, Jürgen, Rothenhäusler, Benno, Perret, Camille, Rogers-Evans, Mark, Kimbara, Atsushi, Nettekoven, Matthias, Guba, Wolfgang, Grether, Uwe, Ullmer, Christoph, Kelly, Melanie E M

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RG7774 (Vicasinabin), an orally bioavailable cannabinoid receptor 2 (CB2R) agonist, decreases retinal vascular permeability, leukocyte adhesion, and ocular inflammation in animal m... von Grether, Uwe, Foxton, Richard H, Gruener, Sabine, Korn, Claudia, Kimbara, Atsushi, Osterwald, Anja, Zirwes, Elisabeth, Uhles, Sabine, Thoele, Janina, Colé, Nadine, Rogers-Evans, Mark, Röver, Stephan, Nettekoven, Matthias, Martin, Rainer E, Adam, Jean-Michel, Fingerle, Jürgen, Bissantz, Caterina, Guba, Wolfgang, Alker, André, Szczesniak, Anna M, Porter, Ross F, Toguri, Tom J, Revelant, Franco, Poirier, Agnès, Perret, Camille, Winther, Lotte, Caruso, Antonello, Fezza, Filomena, Maccarrone, Mauro, Kelly, Melanie E M, Fauser, Sascha, Ullmer, Christoph

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Novel Triazolopyrimidine-Derived Cannabinoid Receptor 2 Agonists as Potential Treatment for Inflammatory Kidney Diseases von Nettekoven, Matthias, Adam, Jean-Michel, Bendels, Stefanie, Bissantz, Catarina, Fingerle, Jürgen, Grether, Uwe, Grüner, Sabine, Guba, Wolfgang, Kimbara, Atsushi, Ottaviani, Giorgio, Püllmann, Bernd, Rogers-Evans, Mark, Röver, Stephan, Rothenhäusler, Benno, Schmitt, Sebastien, Schuler, Franz, Schulz-Gasch, Tanja, Ullmer, Christoph

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BACE1 inhibitors: A head group scan on a series of amides von Woltering, Thomas J., Wostl, Wolfgang, Hilpert, Hans, Rogers-Evans, Mark, Pinard, Emmanuel, Mayweg, Alexander, Göbel, Martin, Banner, David W., Benz, Jörg, Travagli, Massimiliano, Pollastrini, Martina, Marconi, Guido, Gabellieri, Emanuele, Guba, Wolfgang, Mauser, Harald, Andreini, Matteo, Jacobsen, Helmut, Power, Eoin, Narquizian, Robert

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Behavioral analysis through the lifespan of disc1 mutant zebrafish identifies defects in sensorimotor transformation von Pluimer, Brock R., Harrison, Devin L., Boonyavairoje, Chanon, Prinssen, Eric P., Rogers-Evans, Mark, Peterson, Randall T., Thyme, Summer B., Nath, Anjali K.

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Adventures in drug-like chemistry space: from oxetanes to spiroazetidines and beyond von Rogers-Evans, Mark, Knust, Henner, Plancher, Jean-Marc, Carreira, Erick M, Wuitschik, George, Burkhard, Johannes, Li, Dong B, Guérot, Carine

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A Concise Asymmetric Route to the Bridged Bicyclic Tropane Alkaloid Ferruginine Using Enyne Ring-Closing Metathesis von Aggarwal, Varinder K, Astle, Christopher J, Rogers-Evans, Mark

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Inside Cover: Novel Triazolopyrimidine-Derived Cannabinoid Receptor 2 Agonists as Potential Treatment for Inflammatory Kidney Diseases (ChemMedChem 2/2016) von Nettekoven, Matthias, Adam, Jean-Michel, Bendels, Stefanie, Bissantz, Catarina, Fingerle, Jürgen, Grether, Uwe, Grüner, Sabine, Guba, Wolfgang, Kimbara, Atsushi, Ottaviani, Giorgio, Püllmann, Bernd, Rogers-Evans, Mark, Röver, Stephan, Rothenhäusler, Benno, Schmitt, Sebastien, Schuler, Franz, Schulz-Gasch, Tanja, Ullmer, Christoph

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Oxetanes in Drug Discovery: Structural and Synthetic Insights von Wuitschik, Georg, Carreira, Erick M, Wagner, Björn, Fischer, Holger, Parrilla, Isabelle, Schuler, Franz, Rogers-Evans, Mark, Müller, Klaus

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Separation of pyrrolidine allylation products by diastereoselective enzymatic ester hydrolysis von Aggarwal, Varinder K., Astle, Christopher J., Iding, Hans, Wirz, Beat, Rogers-Evans, Mark

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Inside Cover: Spirocyclic Oxetanes: Synthesis and Properties (Angew. Chem. Int. Ed. 24/2008) von Wuitschik, Georg, Rogers-Evans, Mark, Buckl, Andreas, Bernasconi, Maurizio, Märki, Moritz, Godel, Thierry, Fischer, Holger, Wagner, Björn, Parrilla, Isabelle, Schuler, Franz, Schneider, Josef, Alker, André, Schweizer, W. Bernd, Müller, Klaus, Carreira, Erick M.

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