Preclinical overview of sorafenib, a multikinase inhibitor that targets both Raf and VEGF and PDGF receptor tyrosine kinase signaling von Wilhelm, Scott M, Adnane, Lila, Newell, Philippa, Villanueva, Augusto, Llovet, Josep M, Lynch, Mark

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Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5 von LI LIU, YICHEN CAO, CHEN, Charles, XIAOMEI ZHANG, MCNABOLA, Angela, WILKIE, Dean, WILHELM, Scott, LYNCH, Mark, CARTER, Christopher

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Randomized phase 2 study: elotuzumab plus bortezomib/dexamethasone vs bortezomib/dexamethasone for relapsed/refractory MM von Jakubowiak, Andrzej, Offidani, Massimo, Pégourie, Brigitte, De La Rubia, Javier, Garderet, Laurent, Laribi, Kamel, Bosi, Alberto, Marasca, Roberto, Laubach, Jacob, Mohrbacher, Ann, Carella, Angelo Michele, Singhal, Anil K., Tsao, L.Claire, Lynch, Mark, Bleickardt, Eric, Jou, Ying-Ming, Robbins, Michael, Palumbo, Antonio

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Discovery and development of sorafenib: a multikinase inhibitor for treating cancer von Wilhelm, Scott, Carter, Christopher, Lynch, Mark, Lowinger, Timothy, Dumas, Jacques, Smith, Roger A, Schwartz, Brian, Simantov, Ronit, Kelley, Susan

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Predicting Nucleation of Isonicotinamide from the Solvent–Solute Interactions of Isonicotinamide in Common Organic Solvents von Lynch, Mark B, Lawrence, Simon E, Nolan, Michael

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Nivolumab treatment beyond RECIST‐defined progression in recurrent or metastatic squamous cell carcinoma of the head and neck in CheckMate 141: A subgroup analysis of a randomized... von Haddad, Robert, Concha‐Benavente, Fernando, Blumenschein, George, Fayette, Jerome, Guigay, Joel, Colevas, A. Dimitrios, Licitra, Lisa, Kasper, Stefan, Vokes, Everett E., Worden, Francis, Saba, Nabil F., Tahara, Makoto, Jayaprakash, Vijayvel, Lynch, Mark, Li, Li, Gillison, Maura L., Harrington, Kevin J., Ferris, Robert L.

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VKORC1 sequence variants associated with resistance to anticoagulant rodenticides in Irish populations of Rattus norvegicus and Mus musculus domesticus von Mooney, Jean, Lynch, Mark R., Prescott, Colin V., Clegg, Tracy, Loughlin, Michael, Hannon, Bernard, Moore, Colm, Faulkner, Richard

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Advances in Non-Animal Testing Approaches towards Accelerated Clinical Translation of Novel Nanotheranostic Therapeutics for Central Nervous System Disorders von Lynch, Mark J, Gobbo, Oliviero L

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Synergy Assessment of Four Antimicrobial Bioactive Compounds for the Combinational Treatment of Bacterial Pathogens von Masterson, Kevin, Major, Ian, Lynch, Mark, Rowan, Neil

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BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis von WILHELM, Scott M, CARTER, Christopher, CAO, Yichen, SHUJATH, Jaleel, GAWLAK, Susan, EVELEIGH, Deepa, ROWLEY, Bruce, LI LIU, ADNANE, Lila, LYNCH, Mark, AUCLAIR, Daniel, TAYLOR, Ian, TANG, Liya, GEDRICH, Rich, VOZNESENSKY, Andrei, RIEDL, Bernd, POST, Leonard E, BOLLAG, Gideon, TRAIL, Pamela A, WILKIE, Dean, MCNABOLA, Angela, HONG RONG, CHEN, Charles, XIAOMEI ZHANG, VINCENT, Patrick, MCHUGH, Mark

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Miniaturised interaction proteomics on a microfluidic platform with ultra-low input requirements von Furlan, Cristina, Dirks, René A. M., Thomas, Peter C., Jones, Robert C., Wang, Jing, Lynch, Mark, Marks, Hendrik, Vermeulen, Michiel

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Counselling Knowledge and Skills in Papua New Guinea: Identifying the Gaps von Fowler, Jane L, Lynch, Mark P, Larsen, Jennifer

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Breaking cancer diagnosis news remotely during the Covid pandemic von John, Babbin S, Bhudoye, Joshila, Lynch, Mark F

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Hemolysis Rates in Whole Blood Samples for Blood Gas/Electrolyte Analysis by Point-of-Care Testing von Wilson, Amanda, Sweeney, Maranna, Mark Lynch, P L, O'Kane, Maurice J

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Sorafenib (BAY 43-9006) inhibits tumor growth and vascularization and induces tumor apoptosis and hypoxia in RCC xenograft models von CHANG, Yong S, ADNANE, Jalila, WILKIE, Dean, CARTER, Christopher A, TAYLOR, Ian C. A, LYNCH, Mark, WILHELM, Scott, TRAIL, Pamela A, LEVY, Joan, HENDERSON, Arris, DAHAI XUE, BORTOLON, Elizabeth, ICHETOVKIN, Marina, CHEN, Charles, MCNABOLA, Angela

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Preventing the Forgotten Ureteral Stent: Implementation of a Web-Based Stent Registry with Automatic Recall Application von Lynch, Mark F, Ghani, Khurshid R, Frost, Ian, Anson, Ken M

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Quality Error Rates in Point-of-Care Testing von O'KANE, Maurice J, MCMANUS, Paul, MCGOWAN, Noel, LYNCH, P. L. Mark

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Analysis of SARS-CoV-2 antibody seroprevalence in Northern Ireland during 2020–2021 von Greene, Michelle K., Smyth, Peter, English, Andrew, McLaughlin, Joseph, Bucholc, Magda, Bailie, Janice, McCarroll, Julie, McDonnell, Margaret, Watt, Alison, Barnes, George, Lynch, Mark, Duffin, Kevan, Duffy, Gerard, Lewis, Claire, James, Jacqueline A., Stitt, Alan W., Ford, Tom, O'Kane, Maurice, Rai, Taranjit Singh, Bjourson, Anthony J., Cardwell, Christopher, Elborn, J Stuart, Gibson, David S., Scott, Christopher J.

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Microfluidic live tracking and transcriptomics of cancer-immune cell doublets link intercellular proximity and gene regulation von Flores, Bianca C. T., Chawla, Smriti, Ma, Ning, Sanada, Chad, Kujur, Praveen Kumar, Yeung, Rudy, Bellon, Margot B., Hukari, Kyle, Fowler, Brian, Lynch, Mark, Chinen, Ludmilla T. D., Ramalingam, Naveen, Sengupta, Debarka, Jeffrey, Stefanie S.

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Abstract CT099: Nivolumab (nivo) vs investigator's choice (IC) for recurrent or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC): CheckMate-141 von Gillison, Maura L., Blumenschein, George, Fayette, Jérôme, Guigay, Joel, Colevas, A. Dimitrios, Licitra, Lisa, Harrington, Kevin, Kasper, Stefan, Vokes, Everett E., Even, Caroline, Worden, Francis, Saba, Nabil F., Iglesias Docampo, Lara Carmen, Haddad, Robert, Rordorf, Tamara, Kiyota, Naomi, Tahara, Makoto, Monga, Manish, Lynch, Mark, Geese, William J., Schactman, Mark, Kopit, Justin, Shaw, James W., Ferris, Robert L.

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