A primary human macrophage-enteroid co-culture model to investigate mucosal gut physiology and host-pathogen interactions von Noel, Gaelle, Baetz, Nicholas W., Staab, Janet F., Donowitz, Mark, Kovbasnjuk, Olga, Pasetti, Marcela F., Zachos, Nicholas C.

Volltext

Regulatory Binding Partners and Complexes of NHE3 von Donowitz, Mark, Li, Xuhang

Volltext

Human Enteroids as a Model of Upper Small Intestinal Ion Transport Physiology and Pathophysiology von Foulke-Abel, Jennifer, In, Julie, Yin, Jianyi, Zachos, Nicholas C, Kovbasnjuk, Olga, Estes, Mary K, de Jonge, Hugo, Donowitz, Mark

Volltext

Duodenum Intestine-Chip for preclinical drug assessment in a human relevant model von Kasendra, Magdalena, Luc, Raymond, Yin, Jianyi, Manatakis, Dimitris V, Kulkarni, Gauri, Lucchesi, Carolina, Sliz, Josiah, Apostolou, Athanasia, Sunuwar, Laxmi, Obrigewitch, Jenifer, Jang, Kyung-Jin, Hamilton, Geraldine A, Donowitz, Mark, Karalis, Katia

Volltext

Human Intestinal Enteroids: a New Model To Study Human Rotavirus Infection, Host Restriction, and Pathophysiology von Saxena, Kapil, Blutt, Sarah E, Ettayebi, Khalil, Zeng, Xi-Lei, Broughman, James R, Crawford, Sue E, Karandikar, Umesh C, Sastri, Narayan P, Conner, Margaret E, Opekun, Antone R, Graham, David Y, Qureshi, Waqar, Sherman, Vadim, Foulke-Abel, Jennifer, In, Julie, Kovbasnjuk, Olga, Zachos, Nicholas C, Donowitz, Mark, Estes, Mary K

Volltext

Evolutionary origins of eukaryotic sodium/proton exchangers von Brett, Christopher L, Donowitz, Mark, Rao, Rajini

Volltext

A paradox of transcriptional and functional innate interferon responses of human intestinal enteroids to enteric virus infection von Saxena, Kapil, Simon, Lukas M., Zeng, Xi-Lei, Blutt, Sarah E., Crawford, Sue E., Sastri, Narayan P., Karandikar, Umesh C., Ajami, Nadim J., Zachos, Nicholas C., Kovbasnjuk, Olga, Donowitz, Mark, Conner, Margaret E., Shaw, Chad A., Estes, Mary K.

Volltext

Type 1 diabetes human enteroid studies reveal major changes in the intestinal epithelial compartment von Bharadiya, Vishwesh, Rong, Yan, Zhang, Zixin, Lin, Ruxian, Guerrerio, Anthony Lawrence, Tse, C. Ming, Donowitz, Mark, Singh, Varsha

Volltext

Human enteroids as an ex-vivo model of host–pathogen interactions in the gastrointestinal tract von Foulke-Abel, Jennifer, In, Julie, Kovbasnjuk, Olga, Zachos, Nicholas C, Ettayebi, Khalil, Blutt, Sarah E, Hyser, Joseph M, Zeng, Xi-Lei, Crawford, Sue E, Broughman, James R, Estes, Mary K, Donowitz, Mark

Volltext

Has a physiologic function for NHE2 finally been identified? von Donowitz, Mark

Volltext

Anoctamin 1/TMEM16A controls intestinal Cl− secretion induced by carbachol and cholera toxin von Lee, Byeongjun, Hong, Gyu-Sang, Lee, Sung Hoon, Kim, Hyungsup, Kim, Ajung, Hwang, Eun Mi, Kim, Jiyoon, Lee, Min Goo, Yang, Jin-Young, Kweon, Mi-Na, Tse, Chung-Ming, Mark, Donowitz, Oh, Uhtaek

Volltext

mOrange2, a Genetically Encoded, pH Sensitive Fluorescent Protein, is an Alternative to BCECF-AM to Measure Intracellular pH to Determine NHE3 and DRA Activity von Sarker, Rafiquel, Tse, Chung Ming, Lin, Ruxian, McNamara, George, Singh, Varsha, Donowitz, Mark

Volltext

Identification of Intestinal NaCl Absorptive-Anion Secretory Cells: Potential Functional Significance von Donowitz, Mark, Sarker, Rafiquel, Lin, Ruxian, McNamara, George, Tse, Chung Ming, Singh, Varsha

Volltext

Induction of the metal transporter ZIP8 by interferon gamma in intestinal epithelial cells: Potential role of metal dyshomeostasis in Crohn's disease von Melia, Joanna M.P., Lin, Ruxian, Xavier, Ramnik J., Thompson, Richard B., Fu, Dax, Wan, Fengyi, Sears, Cynthia L., Donowitz, Mark

Volltext

Fractionation of Subcellular Membrane Vesicles of Epithelial and Non-epithelial Cells by OptiPrep™ Density Gradient Ultracentrifugation von Li, Xuhang, Donowitz, Mark

Volltext

Epithelial WNT Ligands Are Essential Drivers of Intestinal Stem Cell Activation von Zou, Winnie Y., Blutt, Sarah E., Zeng, Xi-Lei, Chen, Min-Shan, Lo, Yuan-Hung, Castillo-Azofeifa, David, Klein, Ophir D., Shroyer, Noah F., Donowitz, Mark, Estes, Mary K.

Volltext

The burden of selected digestive diseases in the United States von sandler, Robert S., Everhart, James E., Donowitz, Mark, Adams, Elizabeth, Cronin, Kelly, Goodman, Clifford, Gemmen, Eric, Shah, Shefali, Avdic, Aida, Rubin, Robert

Volltext

Identifying the localization and exploring a functional role for Gprc5c in the kidney von Rajkumar, Premraj, Cha, Boyoung, Yin, Jianyi, Arend, Lois J., Păunescu, Teodor G., Hirabayashi, Yoshio, Donowitz, Mark, Pluznick, Jennifer L.

Volltext

Phosphodiesterase 5 (PDE5) restricts intracellular cGMP accumulation during enterotoxigenic Escherichia coli infection von Foulke-Abel, Jennifer, Yu, Huimin, Sunuwar, Laxmi, Lin, Ruxian, Fleckenstein, James M., Kaper, James B., Donowitz, Mark

Volltext

Na+/H+ Exchanger NHE3 Activity and Trafficking Are Lipid Raft-dependent von Murtazina, Rakhilya, Kovbasnjuk, Olga, Donowitz, Mark, Li, Xuhang

Volltext