RAR and RXR modulation in cancer and metabolic disease von Gronemeyer, Hinrich, Altucci, Lucia, Leibowitz, Mark D, Ogilvie, Kathleen M, de Lera, Angel R

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Reduction of Atherosclerosis in Apolipoprotein E Knockout Mice by Activation of the Retinoid X Receptor von Claudel, Thierry, Leibowitz, Mark D., Fiévet, Catherine, Tailleux, Anne, Wagner, Brandee, Repa, Joyce J., Torpier, Gérard, Lobaccaro, Jean-Marc, Paterniti, James R., Mangelsdorf, David J., Heyman, Richard A., Auwerx, Johan

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Effects of Rexinoids on Glucose Transport and Insulin-mediated Signaling in Skeletal Muscles of Diabetic (db/db) Mice von Shen, Qi, Cline, Gary W, Shulman, Gerald I, Leibowitz, Mark D, Davies, Peter J A

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Mechanism of Selective Retinoid X Receptor Agonist-Induced Hypothyroidism in the Rat von Liu, Sha, Ogilvie, Kathleen M, Klausing, Kay, Lawson, Mark A, Jolley, Diane, Li, Danmei, Bilakovics, James, Pascual, Bernadette, Hein, Nancy, Urcan, Mary, Leibowitz, Mark D

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Activation of the Retinoid X Receptor Suppresses Appetite in the Rat von Ogilvie, Kathleen M, Saladin, Régis, Nagy, Tim R, Urcan, Mary S, Heyman, Richard A, Leibowitz, Mark D

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Design, Synthesis, and Structure−Activity Relationship Studies of Novel 6,7-Locked-[7-(2-alkoxy-3,5-dialkylbenzene)-3-methylocta]-2,4,6-trienoic Acids von Michellys, Pierre-Yves, Ardecky, Robert J, Chen, Jyun-Hung, D'Arrigo, Jennifer, Grese, Timothy A, Karanewsky, Donald S, Leibowitz, Mark D, Liu, Sha, Mais, Dale A, Mapes, Christopher M, Montrose-Rafizadeh, Chahrzad, Ogilvie, Katheen M, Reifel-Miller, Anne, Rungta, Deepa, Thompson, Anthony W, Tyhonas, John S, Boehm, Marcus F

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Design, synthesis and structure–activity relationship of novel RXR-selective modulators von Michellys, Pierre-Yves, D'Arrigo, Jennifer, Grese, Timothy A., Karanewsky, Donald S., Leibowitz, Mark D., Mais, Dale A., Mapes, Christopher M., Reifel-Miller, Anne, Rungta, Deepa, Boehm, Marcus F.

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Rosiglitazone induction of Insig-1 in white adipose tissue reveals a novel interplay of peroxisome proliferator-activated receptor gamma and sterol regulatory element-binding prote... von Kast-Woelbern, Heidi R, Dana, Sharon L, Cesario, Rosemary M, Sun, Li, de Grandpre, Louise Y, Brooks, Mason E, Osburn, Deborah L, Reifel-Miller, Anne, Klausing, Kay, Leibowitz, Mark D

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LGD-5552, an Antiinflammatory Glucocorticoid Receptor Ligand with Reduced Side Effects, in Vivo von López, Francisco J, Ardecky, Robert J, Bebo, Bruce, Benbatoul, Khalid, De Grandpre, Louise, Liu, Sha, Leibowitz, Mark D, Marschke, Keith, Rosen, Jon, Rungta, Deepa, Viveros, Humberto O, Yen, Wan-Ching, Zhi, Lin, Negro-Vilar, Andrés, Miner, Jeffrey N

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Molecular Cloning, Expression and Characterization of Human Peroxisome Proliferator Activated Receptors γ1 and γ2 von Elbrecht, Alex, Chen, Yuli, Cullinan, Cathy A., Hayes, Nancy, Leibowitz, Mark D., Moller, David E., Berger, Joel

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Biological Characterization of a Heterodimer-Selective Retinoid X Receptor Modulator: Potential Benefits for the Treatment of Type 2 Diabetes von Leibowitz, Mark D, Ardecky, Robert J, Boehm, Marcus F, Broderick, Carol L, Carfagna, Mark A, Crombie, Diane L, D’Arrigo, Jennifer, Etgen, Garrett J, Faul, Margaret M, Grese, Timothy A, Havel, Henry, Hein, Nancy I, Heyman, Richard A, Jolley, Diane, Klausing, Kay, Liu, Sha, Mais, Dale E, Mapes, Christopher M, Marschke, Keith B, Michellys, Pierre-Yves, Montrose-Rafizadeh, Chahrzad, Ogilvie, Kathleen M, Pascual, Bernadette, Rungta, Deepa, Tyhonas, John S, Urcan, Mary S, Wardlow, Marilyn, Yumibe, Nathan, Reifel-Miller, Anne

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Differential Effects of Rexinoids and Thiazolidinediones on Metabolic Gene Expression in Diabetic Rodents von Singh Ahuja, H, Liu, S, Crombie, D L, Boehm, M, Leibowitz, M D, Heyman, R A, Depre, C, Nagy, L, Tontonoz, P, Davies, P J

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Pharmacological Manipulation of the RAR/RXR Signaling Pathway Maintains the Repopulating Capacity of Hematopoietic Stem Cells in Culture von Safi, Rachid, Muramoto, Garrett G, Salter, Alice B, Meadows, Sarah, Himburg, Heather, Russell, Lauren, Daher, Pamela, Doan, Phuong, Leibowitz, Mark D, Chao, Nelson J, McDonnell, Donald P, Chute, John P

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Metabolic Effects of Rexinoids: Tissue-Specific Regulation of Lipoprotein Lipase Activity von Davies, P J, Berry, S A, Shipley, G L, Eckel, R H, Hennuyer, N, Crombie, D L, Ogilvie, K M, Peinado-Onsurbe, J, Fievet, C, Leibowitz, M D, Heyman, R A, Auwerx, J

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Down-regulation of the Expression of the Obese Gene by an Antidiabetic Thiazolidinedione in Zucker Diabetic Fatty Rats and db/db Mice (∗) von Zhang, Bei, Graziano, Michael P., Doebber, Thomas W., Leibowitz, Mark D., White-Carrington, Sylvia, Szalkowski, Deborah M., Hey, Patricia J., Wu, Margaret, Cullinan, Catherine A., Bailey, Philip, Lollmann, Bettina, Frederich, Robert, Flier, Jeffrey S., Strader, Catherine D., Smith, Roy G.

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Design and synthesis of novel RXR-selective modulators with improved pharmacological profile von Michellys, Pierre-Yves, Boehm, Marcus F, Chen, Jyun-Hung, Grese, Timothy A, Karanewsky, Donald S, Leibowitz, Mark D, Liu, Sha, Mais, Dale A, Mapes, Christopher M, Reifel-Miller, Anne, Ogilvie, Katheen M, Rungta, Deepa, Thompson, Anthony W, Tyhonas, John S, Yumibe, Nathan, Ardecky, Robert J

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Attenuation of colon inflammation through activators of the retinoid X receptor (RXR)/peroxisome proliferator-activated receptor gamma (PPARgamma) heterodimer. A basis for new ther... von Desreumaux, P, Dubuquoy, L, Nutten, S, Peuchmaur, M, Englaro, W, Schoonjans, K, Derijard, B, Desvergne, B, Wahli, W, Chambon, P, Leibowitz, M D, Colombel, J F, Auwerx, J

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Activation of PPARδ alters lipid metabolism in db/db mice von Leibowitz, Mark D., Fiévet, Catherine, Hennuyer, Nathalie, Peinado-Onsurbe, Julia, Duez, Hélène, Berger, Joel, Cullinan, Catherine A., Sparrow, Carl P., Baffic, Joanne, Berger, Gregory D., Santini, Conrad, Marquis, Robert W., Tolman, Richard L., Smith, Roy G., Moller, David E., Auwerx, Johan

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A PPARγ mutant serves as a dominant negative inhibitor of PPAR signaling and is localized in the nucleus von Berger, Joel, Patel, Hansa V, Woods, John, Hayes, Nancy S, Parent, Stephen A, Clemas, Joseph, Leibowitz, Mark D, Elbrecht, Alex, Rachubinski, Richard A, Capone, John P, Moller, David E

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Novel Peroxisome Proliferator-activated Receptor (PPAR) γ and PPARδ Ligands Produce Distinct Biological Effects von Berger, Joel, Leibowitz, Mark D., Doebber, Thomas W., Elbrecht, Alex, Zhang, Bei, Zhou, Gaochou, Biswas, Chhabi, Cullinan, Catherine A., Hayes, Nancy S., Li, Ying, Tanen, Michael, Ventre, John, Wu, Margaret S., Berger, Gregory D., Mosley, Ralph, Marquis, Robert, Santini, Conrad, Sahoo, Soumya P., Tolman, Richard L., Smith, Roy G., Moller, David E.

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