Poised Chromatin at the ZEB1 Promoter Enables Breast Cancer Cell Plasticity and Enhances Tumorigenicity von Chaffer, Christine L., Marjanovic, Nemanja D., Lee, Tony, Bell, George, Kleer, Celina G., Reinhardt, Ferenc, D’Alessio, Ana C., Young, Richard A., Weinberg, Robert A.

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Cell plasticity and heterogeneity in cancer von Marjanovic, Nemanja D, Weinberg, Robert A, Chaffer, Christine L

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Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens von Dixit, Atray, Parnas, Oren, Li, Biyu, Chen, Jenny, Fulco, Charles P., Jerby-Arnon, Livnat, Marjanovic, Nemanja D., Dionne, Danielle, Burks, Tyler, Raychowdhury, Raktima, Adamson, Britt, Norman, Thomas M., Lander, Eric S., Weissman, Jonathan S., Friedman, Nir, Regev, Aviv

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Induction and transcriptional regulation of the co-inhibitory gene module in T cells von Chihara, Norio, Madi, Asaf, Kondo, Takaaki, Zhang, Huiyuan, Acharya, Nandini, Singer, Meromit, Nyman, Jackson, Marjanovic, Nemanja D., Kowalczyk, Monika S., Wang, Chao, Kurtulus, Sema, Law, Travis, Etminan, Yasaman, Nevin, James, Buckley, Christopher D., Burkett, Patrick R., Buenrostro, Jason D., Rozenblatt-Rosen, Orit, Anderson, Ana C., Regev, Aviv, Kuchroo, Vijay K.

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Systematic comparison of single-cell and single-nucleus RNA-sequencing methods von Ding, Jiarui, Adiconis, Xian, Simmons, Sean K., Kowalczyk, Monika S., Hession, Cynthia C., Marjanovic, Nemanja D., Hughes, Travis K., Wadsworth, Marc H., Burks, Tyler, Nguyen, Lan T., Kwon, John Y. H., Barak, Boaz, Ge, William, Kedaigle, Amanda J., Carroll, Shaina, Li, Shuqiang, Hacohen, Nir, Rozenblatt-Rosen, Orit, Shalek, Alex K., Villani, Alexandra-Chloé, Regev, Aviv, Levin, Joshua Z.

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Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness von Katajisto, Pekka, Döhla, Julia, Chaffer, Christine L., Pentinmikko, Nalle, Marjanovic, Nemanja, Iqbal, Sharif, Zoncu, Roberto, Chen, Walter, Weinberg, Robert A., Sabatini, David M.

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A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells von Singer, Meromit, Wang, Chao, Cong, Le, Marjanovic, Nemanja D., Kowalczyk, Monika S., Zhang, Huiyuan, Nyman, Jackson, Sakuishi, Kaori, Kurtulus, Sema, Gennert, David, Xia, Junrong, Kwon, John Y.H., Nevin, James, Herbst, Rebecca H., Yanai, Itai, Rozenblatt-Rosen, Orit, Kuchroo, Vijay K., Regev, Aviv, Anderson, Ana C.

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A Distinct Transcriptional Program in Human CAR T Cells Bearing the 4-1BB Signaling Domain Revealed by scRNA-Seq von Boroughs, Angela C., Larson, Rebecca C., Marjanovic, Nemanja D., Gosik, Kirk, Castano, Ana P., Porter, Caroline B.M., Lorrey, Selena J., Ashenberg, Orr, Jerby, Livnat, Hofree, Matan, Smith-Rosario, Gabriela, Morris, Robert, Gould, Joshua, Riley, Lauren S., Berger, Trisha R., Riesenfeld, Samantha J., Rozenblatt-Rosen, Orit, Choi, Bryan D., Regev, Aviv, Maus, Marcela V.

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Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr5 and Lgr6 von Lee, Joo-Hyeon, Tammela, Tuomas, Hofree, Matan, Choi, Jinwook, Marjanovic, Nemanja Despot, Han, Seungmin, Canner, David, Wu, Katherine, Paschini, Margherita, Bhang, Dong Ha, Jacks, Tyler, Regev, Aviv, Kim, Carla F.

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A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells von Singer, Meromit, Wang, Chao, Cong, Le, Marjanovic, Nemanja D., Kowalczyk, Monika S., Zhang, Huiyuan, Nyman, Jackson, Sakuishi, Kaori, Kurtulus, Sema, Gennert, David, Xia, Junrong, Kwon, John Y.H., Nevin, James, Herbst, Rebecca H., Yanai, Itai, Rozenblatt-Rosen, Orit, Kuchroo, Vijay K., Regev, Aviv, Anderson, Ana C.

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Poised with purpose: Cell plasticity enhances tumorigenicity von Marjanovic, Nemanja D, Weinberg, Robert A., Chaffer, Christine L

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Cancer immunogenomic approach to neoantigen discovery in a checkpoint blockade responsive murine model of oral cavity squamous cell carcinoma von Zolkind, Paul, Przybylski, Dariusz, Marjanovic, Nemanja, Nguyen, Lan, Lin, Tianxiang, Johanns, Tanner, Alexandrov, Anton, Zhou, Liye, Allen, Clint T, Miceli, Alexander P, Schreiber, Robert D, Artyomov, Maxim, Dunn, Gavin P, Uppaluri, Ravindra

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Author Correction: Systematic comparison of single-cell and single-nucleus RNA-sequencing methods von Ding, Jiarui, Adiconis, Xian, Simmons, Sean K., Kowalczyk, Monika S., Hession, Cynthia C., Marjanovic, Nemanja D., Hughes, Travis K., Wadsworth, Marc H., Burks, Tyler, Nguyen, Lan T., Kwon, John Y. H., Barak, Boaz, Ge, William, Kedaigle, Amanda J., Carroll, Shaina, Li, Shuqiang, Hacohen, Nir, Rozenblatt-Rosen, Orit, Shalek, Alex K., Villani, Alexandra-Chloé, Regev, Aviv, Levin, Joshua Z.

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Emergence of a High-Plasticity Cell State during Lung Cancer Evolution von Marjanovic, Nemanja Despot, Hofree, Matan, Chan, Jason E., Canner, David, Wu, Katherine, Trakala, Marianna, Hartmann, Griffin G., Smith, Olivia C., Kim, Jonathan Y., Evans, Kelly Victoria, Hudson, Anna, Ashenberg, Orr, Porter, Caroline B.M., Bejnood, Alborz, Subramanian, Ayshwarya, Pitter, Kenneth, Yan, Yan, Delorey, Toni, Phillips, Devan R., Shah, Nisargbhai, Chaudhary, Ojasvi, Tsankov, Alexander, Hollmann, Travis, Rekhtman, Natasha, Massion, Pierre P., Poirier, John T., Mazutis, Linas, Li, Ruifang, Lee, Joo-Hyeon, Amon, Angelika, Rudin, Charles M., Jacks, Tyler, Regev, Aviv, Tammela, Tuomas

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Abstract A24: Using single-cell RNA-seq approaches to decipher heterogeneity in autochthonous mouse models of small cell lung cancer von Marjanovic, Nemanja Despot, Ng, Sheng Rong, Regev, Aviv, Jacks, Tyler

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Abstract IA34: Targeting cellular heterogeneity in lung adenocarcinoma von Marjanovic, Nemanja, Hofree, Matan, Canner, David, Trakala, Marianna, Wu, Katherine, Smith, Olivia, Kim, Jonathan, Amon, Angelika, Regev, Aviv, Jacks, Tyler, Tammela, Tuomas

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Abstract 1511: A highly plastic cell state emerges during lung adenocarcinoma evolution von Chan, Jason Earl, Marjanovic, Nemanja Despot, Hofree, Matan, Canner, David, Wu, Katherine, Hartmann, Griffin, Smith, Olivia C., Kim, Jonathan, Hudson, Anna, Subramanian, Ayshwarya, Pitter, Kenneth, Rekhtman, Natasha, Massion, Pierre P., Poirier, John T., Rudin, Charles M., Jacks, Tyler, Regev, Aviv, Tammela, Tuomas

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964 Dynamic immune landscapes during melanoma progression reveal a role for endogenous opioids in driving T cell dysfunction von Mangani, Davide, Huang, Linglin, Singer, Meromit, Li, Ruitong, Barilla, Rocky, Escobar, Giulia, Tooley, Katherine, Hanning Cheng, Delaney, Conor, Newcomer, Kathleen, Nyman, Jackson, Marjanovic, Nemanja, Nevin, James, Rozenblatt-Rosen, Orit, Kuchroo, Vijay, Regev, Aviv, Anderson, Ana

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Poised chromatin at the ZEB1 promoter enables cell plasticity and enhances tumorigenicity von Chaffer, Christine L, Marjanovic, Nemanja D, Lee, Tony, Bell, George, Kleer, Celina G, Reinhardt, Ferenc, D'Alessio, Ana C, Young, Richard A, Weinberg, Robert A

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Abstract A10: A distinct gene module for T cell dysfunction uncoupled from T cell activation and controlled by metallothioneins von Singer, Meromit, Wang, Chao, Cong, Le, Marjanovic, Nemanja D., Kowalczyk, Monika S., Zhang, Huiyuan, Nyman, Jackson, Sakuishi, Kaori, Kurtulus, Sema, Gennert, David, Xia, Junrong, Kwon, John YH, Nevin, James, Herbst, Rebecca H., Yanai, Itai, Rozenblatt-Rosen, Orit, Kuchroo, Vijay K., Regev, Aviv, Anderson, Ana C.

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