Loss-of-Function Mutation in Toll-Like Receptor 4 Prevents Diet-Induced Obesity and Insulin Resistance von TSUKUMO, Daniela M. L, CARVALHO-FILHO, Marco A, SAAD, Mario J. A, CARVALHEIRA, José B. C, PRADA, Patricia O, HIRABARA, Sandro M, SCHENKA, André A, ARAUJO, Eliana P, VASSALLO, José, CURI, Rui, VELLOSO, Licio A

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Gut microbiota composition and its effects on obesity and insulin resistance von Caricilli, Andrea M, Saad, Mario J.A

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Physical Exercise Reduces Circulating Lipopolysaccharide and TLR4 Activation and Improves Insulin Signaling in Tissues of DIO Rats von OLIVEIRA, Alexandre G, CARVALHO, Bruno M, TOBAR, Natália, ROPELLE, Eduardo R, PAULI, José R, BAGAROLLI, Renata A, GUADAGNINI, Dioze, CARVALHEIRA, José B. C, SAAD, Mario J. A

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Double-Stranded RNA-Activated Protein Kinase Is a Key Modulator of Insulin Sensitivity in Physiological Conditions and in Obesity in Mice von Carvalho-Filho, M. A, Carvalho, B. M, Oliveira, A. G, Guadagnini, D, Ueno, M, Dias, M. M, Tsukumo, D. M, Hirabara, S. M, Reis, L. F, Curi, R, Carvalheira, J. B.C, Saad, Mario J.A

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Hepatocyte Growth Factor Plays a Key Role in Insulin Resistance-Associated Compensatory Mechanisms von Araújo, Tiago G, Oliveira, Alexandre G, Carvalho, Bruno M, Guadagnini, Dioze, Protzek, André O.P, Carvalheira, Jose B.C, Boschero, Antonio C, Saad, Mario J.A

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Probiotics modulate gut microbiota and improve insulin sensitivity in DIO mice von Bagarolli, Renata A., Tobar, Natália, Oliveira, Alexandre G., Araújo, Tiago G., Carvalho, Bruno M., Rocha, Guilherme Z., Vecina, Juliana F., Calisto, Kelly, Guadagnini, Dioze, Prada, Patrícia O., Santos, Andrey, Saad, Sara T.O., Saad, Mario J.A.

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Shp2 Negatively Regulates Growth in Cardiomyocytes by Controlling Focal Adhesion Kinase/Src and mTOR Pathways von Marin, Talita M, Clemente, Carolina F.M.Z, Santos, Aline M, Picardi, Paty K, Pascoal, Vinícius D.B, Lopes-Cendes, Iscia, Saad, Mário J.A, Franchini, Kleber G

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Exercise Improves Insulin and Leptin Sensitivity in Hypothalamus of Wistar Rats von FLORES, Marcelo B. S, FERNANDES, Maria Fernanda A, ROPELLE, Eduardo R, FARIA, Marcel C, UENO, Mirian, VELLOSO, Licio A, SAAD, Mario J. A, CARVALHEIRA, José B. C

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Blocking iNOS and endoplasmic reticulum stress synergistically improves insulin resistance in mice von Zanotto, Tamires M, Quaresma, Paula G.F, Guadagnini, Dioze, Weissmann, Lais, Santos, Andressa C, Vecina, Juliana F, Calisto, Kelly, Santos, Andrey, Prada, Patrícia O, Saad, Mario J.A

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Tub Has a Key Role in Insulin and Leptin Signaling and Action In Vivo in Hypothalamic Nuclei von PRADA, Patricia O, QUARESMA, Paula G. F, SAAD, Mario J. A, CARICILLI, Andrea M, SANTOS, Andressa C, GUADAGNINI, Dioze, MORARI, Joseane, WEISSMANN, Lais, ROPELLE, Eduardo R, CARVALHEIRA, José Barreto C, VELLOSO, Licio A

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EGFR Tyrosine Kinase Inhibitor (PD153035) Improves Glucose Tolerance and Insulin Action in High-Fat Diet–Fed Mice von PRADA, Patricia O, ROPELLE, Eduardo R, VASSALLO, José, VELLOSO, Licio A, CARVALHEIRA, José B, SAAD, Mario J. A, MOURAO, Rosa H, DE SOUZA, Claudio T, PAULI, Jose R, CINTRA, Dennys E, SCHENKA, André, ROCCO, Silvana A, RITTNER, Roberto, FRANCHINI, Kleber G

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Diet-induced obesity induces endoplasmic reticulum stress and insulin resistance in the amygdala of rats von Castro, Gisele, C. Areias, Maria Fernanda, Weissmann, Lais, Quaresma, Paula G.F., Katashima, Carlos K., Saad, Mario J.A., Prada, Patricia O.

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Metformin Amplifies Chemotherapy-Induced AMPK Activation and Antitumoral Growth von ROCHA, Guilherme Z, DIAS, Marília M, ROPELLE, Eduardo R, OSORIO-COSTA, Felipe, ROSSATO, Franco A, VERCESI, Anibal E, SAAD, Mario J. A, CARVALHEIRA, José B. C

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Gut microbiota is a key modulator of insulin resistance in TLR 2 knockout mice von Caricilli, Andréa M, Picardi, Paty K, de Abreu, Lélia L, Ueno, Mirian, Prada, Patrícia O, Ropelle, Eduardo R, Hirabara, Sandro Massao, Castoldi, Ângela, Vieira, Pedro, Camara, Niels O S, Curi, Rui, Carvalheira, José B, Saad, Mário J A

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Defective Insulin and Acetylcholine Induction of Endothelial Cell–Nitric Oxide Synthase Through Insulin Receptor Substrate/Akt Signaling Pathway in Aorta of Obese Rats von ZECCHIN, Henrique G, PRIVIERO, Fernanda B. M, SOUZA, Claudio T, ZECCHIN, Karina G, PRADO, Patricia O, CARVALHEIRA, José B. C, VELLOSO, Licio A, ANTUNES, Edson, SAAD, Mario J. A

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IL-6 and IL-10 Anti-Inflammatory Activity Links Exercise to Hypothalamic Insulin and Leptin Sensitivity through IKKβ and ER Stress Inhibition von Ropelle, Eduardo R, Flores, Marcelo B, Cintra, Dennys E, Rocha, Guilherme Z, Pauli, Jose R, Morari, Joseane, de Souza, Claudio T, Moraes, Juliana C, Prada, Patricia O, Guadagnini, Dioze, Marin, Rodrigo M, Oliveira, Alexandre G, Augusto, Taize M, Carvalho, Hernandes F, Velloso, Licio A, Saad, Mario J.A, Carvalheira, Jose B.C

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Oral supplementation with l -glutamine alters gut microbiota of obese and overweight adults: A pilot study von Zambom de Souza, Alessandra Zanin, M.A, Zambom, Adriano Zanin, Ph.D, Abboud, Kahlile Youssef, M.A, Reis, Sabrina Karen, M.A, Tannihão, Fabiana, B.A, Guadagnini, Dioze, M.A, Saad, Mario J.A., Ph.D, Prada, Patricia Oliveira, Ph.D

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Targeted Disruption of Inducible Nitric Oxide Synthase Protects Against Aging, S-Nitrosation, and Insulin Resistance in Muscle of Male Mice von ROPELLE, Eduardo R, PAULI, Jose R, HIRABARA, Sandro, RUI CURI, VELLOSO, Licio A, SAAD, Mario J. A, CARVALHEIRA, Jose B. C, CINTRA, Dennys E, DA SILVA, Adelino S, DE SOUZA, Claudio T, GUADAGNINI, Dioze, CARVALHO, Bruno M, CARICILLI, Andrea M, KATASHIMA, Carlos K, CARVALHO-FILHO, Marco A

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A Central Role for Neuronal AMP-Activated Protein Kinase (AMPK) and Mammalian Target of Rapamycin (mTOR) in High-Protein Diet–Induced Weight Loss von ROPELLE, Eduardo R, PAULI, José R, FRANCHINI, Kleber G, VELLOSO, Licio A, SAAD, Mario J. A, CARVALHEIRA, José B. C, FERNANDES, Maria Fernanda A, ROCCO, Silvana A, MARIN, Rodrigo M, MORARI, Joseane, SOUZA, Kellen K, DIAS, Marilia M, GOMES-MARCONDES, Maria C, GONTIJO, José A. R

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S-nitrosation of the insulin receptor, insulin receptor substrate 1, and protein kinase B/Akt : A novel mechanism of insulin resistance von CARVALHO-FILHO, Marco A, UENO, Mirian, HIRABARA, Sandro M, SEABRA, Amedea B, CARVAIHEIRA, José B. C, DE OLIVEIRA, Marcelo G, VELLOSO, Licio A, CURI, Rui, SAAD, Mario J. A

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