Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy von Seo, Kinya, Rainer, Peter P., Hahn, Virginia Shalkey, Lee, Dong-ik, Jo, Su-Hyun, Andersen, Asger, Liu, Ting, Xu, Xiaoping, Willette, Robert N., Lepore, John J., Marino, Joseph P., Birnbaumer, Lutz, Schnackenberg, Christine G., Kass, David A.

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Enantioselective Synthesis of Dihydro‑1H‑benzindoles von Silveira, Gustavo P, Marino, Joseph P

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The discovery of potent blockers of the canonical transient receptor channels, TRPC3 and TRPC6, based on an anilino-thiazole pharmacophore von Washburn, David G., Holt, Dennis A., Dodson, Jason, McAtee, Jeff J., Terrell, Lamont R., Barton, Linda, Manns, Sharada, Waszkiewicz, Anna, Pritchard, Christina, Gillie, Dan J., Morrow, Dwight M., Davenport, Elizabeth A., Lozinskaya, Irina M., Guss, Jeffrey, Basilla, Jonathan B., Negron, Lorena Kallal, Klein, Michael, Willette, Robert N., Fries, Rusty E., Jensen, Timothy C., Xu, Xiaoping, Schnackenberg, Christine G., Marino, Joseph P.

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Discovery of 1-(1,3,5-triazin-2-yl)piperidine-4-carboxamides as inhibitors of soluble epoxide hydrolase von Thalji, Reema K., McAtee, Jeff J., Belyanskaya, Svetlana, Brandt, Martin, Brown, Gregory D., Costell, Melissa H., Ding, Yun, Dodson, Jason W., Eisennagel, Steve H., Fries, Rusty E., Gross, Jeffrey W., Harpel, Mark R., Holt, Dennis A., Israel, David I., Jolivette, Larry J., Krosky, Daniel, Li, Hu, Lu, Quinn, Mandichak, Tracy, Roethke, Theresa, Schnackenberg, Christine G., Schwartz, Benjamin, Shewchuk, Lisa M., Xie, Wensheng, Behm, David J., Douglas, Stephen A., Shaw, Ami L., Marino, Joseph P.

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In vitro and in vivo characterization of a novel soluble epoxide hydrolase inhibitor von Podolin, Patricia L., Bolognese, Brian J., Foley, Joseph F., Long, Edward, Peck, Brian, Umbrecht, Sandra, Zhang, Xiaojun, Zhu, Penny, Schwartz, Benjamin, Xie, Wensheng, Quinn, Chad, Qi, Hongwei, Sweitzer, Sharon, Chen, Stephanie, Galop, Marc, Ding, Yun, Belyanskaya, Svetlana L., Israel, David I., Morgan, Barry A., Behm, David J., Marino, Joseph P., Kurali, Edit, Barnette, Mary S., Mayer, Ruth J., Booth-Genthe, Catherine L., Callahan, James F.

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Soluble epoxide hydrolase inhibition exerts beneficial anti-remodeling actions post-myocardial infarction von Kompa, Andrew R, Wang, Bing H, Xu, Guoying, Zhang, Yuan, Ho, Pei-Yu, Eisennagel, Stephen, Thalji, Reema K, Marino, Joseph P, Kelly, Darren J, Behm, David J, Krum, Henry

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Stereocontrolled Synthesis of (−)-Macrolactin A von Marino, Joseph P, McClure, Michael S, Holub, David P, Comasseto, João V, Tucci, Fabío C

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Total Synthesis of (+)-Aspidospermidine:  A New Strategy for the Enantiospecific Synthesis of Aspidosperma Alkaloids von Marino, Joseph P, Rubio, Maria B, Cao, Ganfeng, de Dios, Alfonso

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Synthetic LXR agonists increase LDL in CETP species von Groot, Pieter H. E, Pearce, Nigel J, Yates, John W, Stocker, Claire, Sauermelch, Charles, Doe, Christopher P, Willette, Robert N, Olzinski, Alan, Peters, Tambra, d'Epagnier, Denise, Morasco, Kathleen O, Krawiec, John A, Webb, Christine L, Aravindhan, Karpagam, Jucker, Beat, Burgert, Mark, Ma, Chun, Marino, Joseph P, Collins, Jon L, Macphee, Colin H, Thompson, Scott K, Jaye, Michael

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Orai and TRPC channel characterization in FcεRI‐mediated calcium signaling and mediator secretion in human mast cells von Wajdner, Hannah E., Farrington, Jasmine, Barnard, Claire, Peachell, Peter T., Schnackenberg, Christine G., Marino, Joseph P., Xu, Xiaoping, Affleck, Karen, Begg, Malcolm, Seward, Elizabeth P.

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Highly Potent Inhibitors of Methionine Aminopeptidase-2 Based on a 1,2,4-Triazole Pharmacophore von Marino, Joseph P, Fisher, Paul W, Hofmann, Glenn A, Kirkpatrick, Robert B, Janson, Cheryl A, Johnson, Randall K, Ma, Chun, Mattern, Michael, Meek, Thomas D, Ryan, M. Dominic, Schulz, Christina, Smith, Ward W, Tew, David G, Tomazek, Thaddeus A, Veber, Daniel F, Xiong, Wenfang C, Yamamoto, Yuuichi, Yamashita, Keizo, Yang, Guang, Thompson, Scott K

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Discovery of soluble epoxide hydrolase inhibitors through DNA-encoded library technology (ELT) von Ding, Yun, Belyanskaya, Svetlana, DeLorey, Jennifer L., Messer, Jeffrey A., Joseph Franklin, G., Centrella, Paolo A., Morgan, Barry A., Clark, Matthew A., Skinner, Steven R., Dodson, Jason W., Li, Peng, Marino, Joseph P., Israel, David I.

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Soluble Epoxide Hydrolase Inhibition Does Not Prevent Cardiac Remodeling and Dysfunction After Aortic Constriction in Rats and Mice von Morgan, Lisa A, Olzinski, Alan R, Upson, John J, Zhao, Shufang, Wang, Tao, Eisennagel, Stephen H, Hoang, Bao, Tunstead, James R, Marino, Joseph P, Willette, Robert N, Jucker, Beat M, Behm, David J

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Benzofuran-substituted urea derivatives as novel P2Y(1) receptor antagonists von Thalji, Reema K, Aiyar, Nambi, Davenport, Elizabeth A, Erhardt, Joseph A, Kallal, Lorena A, Morrow, Dwight M, Senadhi, Shobha, Burns-Kurtis, Cynthia L, Marino, Jr, Joseph P

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Enantiodivergent Total Syntheses of (+)- and (−)-Scopadulcic Acid A von Fox, Martin E, Li, Chi, Marino, Joseph P, Overman, Larry E

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Discovery of Aminofurazan-azabenzimidazoles as Inhibitors of Rho-Kinase with High Kinase Selectivity and Antihypertensive Activity von Stavenger, Robert A, Cui, Haifeng, Dowdell, Sarah E, Franz, Robert G, Gaitanopoulos, Dimitri E, Goodman, Krista B, Hilfiker, Mark A, Ivy, Robert L, Leber, Jack D, Marino, Joseph P, Oh, Hye-Ja, Viet, Andrew Q, Xu, Weiwei, Ye, Guosen, Zhang, Daohua, Zhao, Yongdong, Jolivette, Larry J, Head, Martha S, Semus, Simon F, Elkins, Patricia A, Kirkpatrick, Robert B, Dul, Edward, Khandekar, Sanjay S, Yi, Tracey, Jung, David K, Wright, Lois L, Smith, Gary K, Behm, David J, Doe, Christopher P, Bentley, Ross, Chen, Zunxuan X, Hu, Erding, Lee, Dennis

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Electrotelluration:  A New Approach to Tri- and Tetrasubstituted Alkenes von Marino, Joseph P, Nguyen, Hanh Nho

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Benzofuran-substituted urea derivatives as novel P2Y1 receptor antagonists von Thalji, Reema K., Aiyar, Nambi, Davenport, Elizabeth A., Erhardt, Joseph A., Kallal, Lorena A., Morrow, Dwight M., Senadhi, Shobha, Burns-Kurtis, Cynthia L., Marino, Joseph P.

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Steady-State Kinetic Characterization of Substrates and Metal-Ion Specificities of the Full-Length and N-Terminally Truncated Recombinant Human Methionine Aminopeptidases (Type 2) von Yang, Guang, Kirkpatrick, Robert B, Ho, Thau, Zhang, Gui-Feng, Liang, Po-Huang, Johanson, Kyung O, Casper, David J, Doyle, Michael L, Marino, Joseph P, Thompson, Scott K, Chen, Wenfang, Tew, David G, Meek, Thomas D

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Tetrahydro-4-quinolinamines identified as novel P2Y(1) receptor antagonists von Morales-Ramos, Angel I, Mecom, John S, Kiesow, Terry J, Graybill, Todd L, Brown, Gregory D, Aiyar, Nambi V, Davenport, Elizabeth A, Kallal, Lorena A, Knapp-Reed, Beth A, Li, Peng, Londregan, Allyn T, Morrow, Dwight M, Senadhi, Shobha, Thalji, Reema K, Zhao, Steve, Burns-Kurtis, Cynthia L, Marino, Jr, Joseph P

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