Integrator Regulates Transcriptional Initiation and Pause Release following Activation von Gardini, Alessandro, Baillat, David, Cesaroni, Matteo, Hu, Deqing, Marinis, Jill M., Wagner, Eric J., Lazar, Mitchell A., Shilatifard, Ali, Shiekhattar, Ramin

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Autophagy protein ATG16L1 prevents necroptosis in the intestinal epithelium von Matsuzawa-Ishimoto, Yu, Shono, Yusuke, Gomez, Luis E, Hubbard-Lucey, Vanessa M, Cammer, Michael, Neil, Jessica, Dewan, M Zahidunnabi, Lieberman, Sophia R, Lazrak, Amina, Marinis, Jill M, Beal, Allison, Harris, Philip A, Bertin, John, Liu, Chen, Ding, Yi, van den Brink, Marcel R M, Cadwell, Ken

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Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity von Dallner, Olof S., Marinis, Jill M., Lu, Yi-Hsueh, Birsoy, Kivanc, Werner, Emory, Fayzikhodjaeva, Gulya, Dill, Brian D., Molina, Henrik, Moscati, Arden, Kutalik, Zoltán, Marques-Vidal, Pedro, Kilpeläinen, Tuomas O., Grarup, Niels, Linneberg, Allan, Zhang, Yinxin, Vaughan, Roger, Loos, Ruth J. F., Lazar, Mitchell A., Friedman, Jeffrey M.

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PPARγ is a nexus controlling alternative activation of macrophages via glutamine metabolism von Nelson, Victoria L, Nguyen, Hoang C B, Garcìa-Cañaveras, Juan C, Briggs, Erika R, Ho, Wesley Y, DiSpirito, Joanna R, Marinis, Jill M, Hill, David A, Lazar, Mitchell A

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Genetic Variation Determines PPARγ Function and Anti-diabetic Drug Response In Vivo von Soccio, Raymond E., Chen, Eric R., Rajapurkar, Satyajit R., Safabakhsh, Pegah, Marinis, Jill M., Dispirito, Joanna R., Emmett, Matthew J., Briggs, Erika R., Fang, Bin, Everett, Logan J., Lim, Hee-Woong, Won, Kyoung-Jae, Steger, David J., Wu, Ying, Civelek, Mete, Voight, Benjamin F., Lazar, Mitchell A.

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RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer von Wang, Wei, Marinis, Jill M., Beal, Allison M., Savadkar, Shivraj, Wu, Yue, Khan, Mohammed, Taunk, Pardeep S., Wu, Nan, Su, Wenyu, Wu, Jingjing, Ahsan, Aarif, Kurz, Emma, Chen, Ting, Yaboh, Inedouye, Li, Fei, Gutierrez, Johana, Diskin, Brian, Hundeyin, Mautin, Reilly, Michael, Lich, John D., Harris, Philip A., Mahajan, Mukesh K., Thorpe, James H., Nassau, Pamela, Mosley, Julie E., Leinwand, Joshua, Kochen Rossi, Juan A., Mishra, Ankita, Aykut, Berk, Glacken, Michael, Ochi, Atsuo, Verma, Narendra, Kim, Jacqueline I., Vasudevaraja, Varshini, Adeegbe, Dennis, Almonte, Christina, Bagdatlioglu, Ece, Cohen, Deirdre J., Wong, Kwok-Kin, Bertin, John, Miller, George

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ITCH K63-Ubiquitinates the NOD2 Binding Protein, RIP2, to Influence Inflammatory Signaling Pathways von Tao, MingFang, Scacheri, Peter C., Marinis, Jill M., Harhaj, Edward W., Matesic, Lydia E., Abbott, Derek W.

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Identification of a RIP1 Kinase Inhibitor Clinical Candidate (GSK3145095) for the Treatment of Pancreatic Cancer von Harris, Philip A, Marinis, Jill M, Lich, John D, Berger, Scott B, Chirala, Anirudh, Cox, Julie A, Eidam, Patrick M, Finger, Joshua N, Gough, Peter J, Jeong, Jae U, Kang, James, Kasparcova, Viera, Leister, Lara K, Mahajan, Mukesh K, Miller, George, Nagilla, Rakesh, Ouellette, Michael T, Reilly, Michael A, Rendina, Alan R, Rivera, Elizabeth J, Sun, Helen H, Thorpe, James H, Totoritis, Rachel D, Wang, Wei, Wu, Dongling, Zhang, Daohua, Bertin, John, Marquis, Robert W

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Anti-diabetic rosiglitazone remodels the adipocyte transcriptome by redistributing transcription to PPARγ-driven enhancers von Step, Sonia E, Lim, Hee-Woong, Marinis, Jill M, Prokesch, Andreas, Steger, David J, You, Seo-Hee, Won, Kyoung-Jae, Lazar, Mitchell A

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A Novel Motif in the Crohn's Disease Susceptibility Protein, NOD2, Allows TRAF4 to Down-regulate Innate Immune Responses von Marinis, Jill M., Homer, Craig R., McDonald, Christine, Abbott, Derek W.

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RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer von Wang, Wei, Marinis, Jill M., Beal, Allison M., Savadkar, Shivraj, Wu, Yue, Khan, Mohammed, Taunk, Pardeep S., Wu, Nan, Su, Wenyu, Wu, Jingjing, Ahsan, Aarif, Kurz, Emma, Chen, Ting, Yaboh, Inedouye, Li, Fei, Gutierrez, Johana, Diskin, Brian, Hundeyin, Mautin, Reilly, Michael, Lich, John D., Harris, Philip A., Mahajan, Mukesh K., Thorpe, James H., Nassau, Pamela, Mosley, Julie E., Leinwand, Joshua, Kochen Rossi, Juan A., Mishra, Ankita, Aykut, Berk, Glacken, Michael, Ochi, Atsuo, Verma, Narendra, Kim, Jacqueline I., Vasudevaraja, Varshini, Adeegbe, Dennis, Almonte, Christina, Bagdatlioglu, Ece, Cohen, Deirdre J., Wong, Kwok-Kin, Bertin, John, Miller, George

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IκB Kinase α Phosphorylation of TRAF4 Downregulates Innate Immune Signaling von Marinis, Jill M., Hutti, Jessica E., Homer, Craig R., Cobb, Brian A., Cantley, Lewis C., McDonald, Christine, Abbott, Derek W.

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Innate Immune-Directed NF-κB Signaling Requires Site-Specific NEMO Ubiquitination von Jun, Janice C., Kertesy, Sylvia, Jones, Mark B., Marinis, Jill M., Cobb, Brian A., Tigno-Aranjuez, Justine T., Abbott, Derek W.

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Application of DMPK toolbox in predicting human pharmacokinetics for back-up RIP1 inhibitors: Learnings from GSK2982772 in clinic von Mahajan, Mukesh, Harris, Phil, Zhang, David, Richards-Peterson, Lauren, Thomas, Steven, Tompson, Debbie, Marinis, Jill, Berger, Scott, Marquis, Robert, Bertin, John, Reilly, Michael

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MEKK4 Sequesters RIP2 to Dictate NOD2 Signal Specificity von Clark, Nivedita M., Marinis, Jill M., Cobb, Brian A., Abbott, Derek W.

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A phase I/II study of GSK3145095 alone and in combination with anticancer agents including pembrolizumab in adults with selected solid tumors von Cohen, Deirdre Jill, Pant, Shubham, O'Neil, Bert, Marinis, Jill, Winnberg, James, Ahlers, Christoph Matthias, Callaway, Justin, Rathi, Chetan, Acusta, Andre, Verticelli, Adeline, Bertin, John, Smothers, James F .

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Tu1900 Defective NOD2 Signaling and Innate Cytokine Production in Response to MDP in Experimental Crohn's Disease (CD) von Corridoni, Daniele, Marinis, Jill, Abbott, Derek, Cominelli, Fabio

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Targeting inhibitors of NOD2 signaling to allow productive inflammation in genetic inflammatory disease (157.9) von Marinis, Jill, Homer, Craig, McDonald, Christine, Abbott, Derek

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CS05-5. Defective Nod2 Signaling And Innate Cytokine Production In Response To Mdp In Experimental Crohn’s Disease (CD) von Corridoni, Daniele, Marinis, Jill, Abbott, Derek, Cominelli, Fabio

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I?B Kinase ? Phosphorylation of TRAF4 Downregulates Innate Immune Signaling von Marinis, Jill M, Hutti, Jessica E, Homer, Craig R, Cobb, Brian A, Cantley, Lewis C, McDonald, Christine, Abbott, Derek W

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