Prospective DPYD testing in colorectal cancer patients in a realworld UK population von Eccles, B K, Harle, A S, Pullinger, S, Holling, C, Ingram, A, Stark, S, Bunce, M, Melville, G, Gibbins, J, Calcutt, N, Hickish, T, Flubacher, M, Marinaki, T

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560PProspective DPYD testing in colorectal cancer patients in a realworld UK population von Eccles, B K, Harle, A S, Pullinger, S, Holling, C, Ingram, A, Stark, S, Bunce, M, Melville, G, Gibbins, J, Calcutt, N, Hickish, T, Flubacher, M, Marinaki, T

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Lactate Threshold does not Influence Metabolic Responses during Exercise in Cyclists von Bentley, D. J., McNaughton, L. R., Roberts, S., Vleck, V. E., Fairbanks, L., Marinaki, T.

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404MO Clinical relevance of MIR27A rs895819 polymorphism and its interaction with DPYD variants for predicting grade 4-5 fluoropyrimidine (FP) toxicity (tox) in the FUSAFE individu... von Etienne-Grimaldi, M-C., Cozic, N., Boige, V., Boyer, J-C., Meulendijks, D., Palles, C., Zanger, U., Largiadèr, C., Diasio, R.B., Jennings, B., Taieb, J., Deenen, M., Marinaki, T., Gross, E., van Kuilenburg, A., Thomas-Jean, F., Loriot, M-A., Pignon, J-P., Le Teuff, G.

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Dpyd Genotyping As a Predictive Biomarker of Toxicity in Breast Cancer von Papadatos-Pastos, D., De Souza, K., Karapanagiotou, L., Sandri, I., Marinaki, T., Mansi, J.L.

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408PDPYD GENOTYPING AS A PREDICTIVE BIOMARKER OF TOXICITY IN BREAST CANCER von Papadatos-Pastos, D., De Souza, K., Karapanagiotou, L., Sandri, I., Marinaki, T., Mansi, J.L.

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Long-term outcomes and prognostic factors for survival of patients with ANCA-associated vasculitis von Sánchez Álamo, Beatriz, Moi, Laura, Bajema, Ingeborg, Faurschou, Mikkel, Flossmann, Oliver, Hauser, Thomas, Hruskova, Zdenka, Jayne, David, Luqmani, Raashid, Mahr, Alfred, Åkesson, Anna, Westman, Kerstin

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PWE-111 Higher Red Blood Cell Methotrexate Polyglutamates Correlate With Increased Disease Activity, And Are Useful In Assessing Adherence von Fong, S, Ward, MG, Nasr, I, Goel, RM, Patel, KV, Ray, S, Arenas Hernandez, M, Anderson, SA, Marinaki, T, Sanderson, JD, Irving, PM

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PWE-111Higher Red Blood Cell Methotrexate Polyglutamates Correlate With Increased Disease Activity, And Are Useful In Assessing Adherence von Fong, S, Ward, M G, Nasr, I, Goel, R M, Patel, K V, Ray, S, Arenas Hernandez, M, Anderson, SA, Marinaki, T, Sanderson, J D, Irving, P M

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PWE-111 Higher Red Blood Cell Methotrexate Polyglutamates Correlate With Increased Disease Activity, And Are Useful In Assessing Adherence: Abstract PWE-111 Table 1 von Fong, S, Ward, MG, Nasr, I, Goel, RM, Patel, KV, Ray, S, Arenas Hernandez, M, Anderson, SA, Marinaki, T, Sanderson, JD, Irving, PM

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Adenine phosphoribosyltransferase deficiency in the United Kingdom: two novel mutations and a cross-sectional survey von Balasubramaniam, Gowrie S., Arenas-Hernandez, Monica, Escuredo, Emilia, Fairbanks, Lynette, Marinaki, Tony, Mapplebeck, Sarah, Sheaff, Michael, Almond, Michael K.

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P469 Higher red blood cell methotrexate polyglutamates correlate with increased disease activity, and are useful in assessing adherence von Fong, S., Ward, M.G., Nasr, I., Goel, R.M., Patel, K.V., Ray, S., Arenas Hernandez, M., Anderson, S.A., Marinaki, T., Sanderson, J.D., Irving, P.M.

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Mapping the Paediatric Quality of Life Inventory (PedsQL™) Generic Core Scales onto the Child Health Utility Index–9 Dimension (CHU-9D) Score for Economic Evaluation in Children... von Lambe, Tosin, Frew, Emma, Ives, Natalie J., Woolley, Rebecca L., Cummins, Carole, Brettell, Elizabeth A., Barsoum, Emma N., Webb, Nicholas J. A.

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PTH-062 Treating TPMT Deficient Patients with Thiopurines: A Tertiary IBD Centre Experience von Johnston, EL, Warner, BD, Fong, SC, Blaker, PA, Arenas-Hernandez, M, Marinaki, TM, Anderson, S, Irving, PM, Sanderson, JD

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PWE-013 Should The Target TGN Range Be Different in Those with Intermediate Compared with Normal TPMT Activity? von Johnston, EL, Warner, BD, Fong, SC, Ward, MG, Kariyawasam, V, Arenas-Hernandez, M, Marinaki, TM, Sanderson, JD, Blaker, PA

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Difficulties and possibilities with thiopurine therapy in inflammatory bowel disease—Proceedings of the first Thiopurine Task Force meeting von van Asseldonk, Dirk P, Sanderson, Jeremy, de Boer, Nanne K.H, Sparrow, Miles P, Lémann, Marc, Ansari, Azhar, Almer, Sven H, Florin, Timothy H.J, Gearry, Richard B, Mulder, Chris J, Mantzaris, Gerassimos, van Bodegraven, Ad A

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Suboptimal management of central nervous system infections in children: a multi-centre retrospective study von Kelly, Christine, Sohal, Aman, Michael, Benedict D, Riordan, Andrew, Solomon, Tom, Kneen, Rachel

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C677T and A1298C methylenetetrahydrofolate reductase gene polymorphism does not predict toxicity or efficacy of methotrexate in patients with inflammatory bowel disease von Soon, S.Y, Ansari, A, Hernandez, M, Marinaki, T, Sanderson, J.D

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Acute central nervous system infections in adults—a retrospective cohort study in the NHS North West region von Michael, B.D., Sidhu, M., Stoeter, D., Roberts, M., Beeching, N.J., Bonington, A., Hart, I.J., Kneen, R., Miller, A., Solomon, T.

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Prospective study of thioguanine nucleotide measurement during azathioprine treatment for inflammatory bowel disease von Ansari, A, Arenas, M, Lindsay, J, Morris, D, Greenfield, S, Soon, S.L, Fairbanks, S, Duley, J, Marinaki, T, Sanderson, J

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