Key Roles of AXL and MER Receptor Tyrosine Kinases in Resistance to Multiple Anticancer Therapies von Schoumacher, Marie, Burbridge, Mike

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Cancer-associated fibroblasts induce metalloprotease-independent cancer cell invasion of the basement membrane von Glentis, Alexandros, Oertle, Philipp, Mariani, Pascale, Chikina, Aleksandra, El Marjou, Fatima, Attieh, Youmna, Zaccarini, Francois, Lae, Marick, Loew, Damarys, Dingli, Florent, Sirven, Philemon, Schoumacher, Marie, Gurchenkov, Basile G., Plodinec, Marija, Vignjevic, Danijela Matic

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Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia von Schoumacher, Marie, Goldman, Robert D, Louvard, Daniel, Vignjevic, Danijela M

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AURKB as a target in non-small cell lung cancer with acquired resistance to anti-EGFR therapy von Bertran-Alamillo, Jordi, Cattan, Valérie, Schoumacher, Marie, Codony-Servat, Jordi, Giménez-Capitán, Ana, Cantero, Frédérique, Burbridge, Mike, Rodríguez, Sonia, Teixidó, Cristina, Roman, Ruth, Castellví, Josep, García-Román, Silvia, Codony-Servat, Carles, Viteri, Santiago, Cardona, Andrés-Felipe, Karachaliou, Niki, Rosell, Rafael, Molina-Vila, Miguel-Angel

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Preclinical evaluation of the simultaneous inhibition of MCL-1 and BCL-2 with the combination of S63845 and venetoclax in multiple myeloma von Algarín, Esperanza M, Díaz-Tejedor, Andrea, Mogollón, Pedro, Hernández-García, Susana, Corchete, Luis A, San-Segundo, Laura, Martín-Sánchez, Montserrat, González-Méndez, Lorena, Schoumacher, Marie, Banquet, Sebastien, Kraus-Berthier, Laurence, Kloos, Ioana, Derreal, Alix, Halilovic, Ensar, Maacke, Heiko, Gutiérrez, Norma C, Mateos, María-Victoria, Paíno, Teresa, Garayoa, Mercedes, Ocio, Enrique M

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ERG signaling in prostate cancer is driven through PRMT5-dependent methylation of the Androgen Receptor von Mounir, Zineb, Korn, Joshua M, Westerling, Thomas, Lin, Fallon, Kirby, Christina A, Schirle, Markus, McAllister, Gregg, Hoffman, Greg, Ramadan, Nadire, Hartung, Anke, Feng, Yan, Kipp, David Randal, Quinn, Christopher, Fodor, Michelle, Baird, Jason, Schoumacher, Marie, Meyer, Ronald, Deeds, James, Buchwalter, Gilles, Stams, Travis, Keen, Nicholas, Sellers, William R, Brown, Myles, Pagliarini, Raymond A

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AXL Controls Directed Migration of Mesenchymal Triple-Negative Breast Cancer Cells von Zajac, Olivier, Leclere, Renaud, Nicolas, André, Meseure, Didier, Marchiò, Caterina, Vincent-Salomon, Anne, Roman-Roman, Sergio, Schoumacher, Marie, Dubois, Thierry

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Upcoming translational challenges for uveal melanoma von Nabil, Amirouchene-Angelozzi, Marie, Schoumacher, Marc-Henri, Stern, Nathalie, Cassoux, Laurence, Desjardins, Sophie, Piperno-Neumann, Olivier, Lantz, Sergio, Roman-Roman

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Author Correction: Cancer-associated fibroblasts induce metalloprotease-independent cancer cell invasion of the basement membrane von Glentis, Alexandros, Oertle, Philipp, Mariani, Pascale, Chikina, Aleksandra, El Marjou, Fatima, Attieh, Youmna, Zaccarini, Francois, Lae, Marick, Loew, Damarys, Dingli, Florent, Sirven, Philemon, Schoumacher, Marie, Gurchenkov, Basile G., Plodinec, Marija, Vignjevic, Danijela Matic

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Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias von Thijssen, Rachel, Diepstraten, Sarah T., Moujalled, Donia, Chew, Edward, Flensburg, Christoffer, Shi, Melissa X., Dengler, Michael A., Litalien, Veronique, MacRaild, Sarah, Chen, Maoshan, Anstee, Natasha S., Reljić, Boris, Gabriel, Sarah S., Djajawi, Tirta M., Riffkin, Chris D., Aubrey, Brandon J., Chang, Catherine, Tai, Lin, Xu, Zhen, Morley, Thomas, Pomilio, Giovanna, Bruedigam, Claudia, Kallies, Axel, Stroud, David A., Bajel, Ashish, Kluck, Ruth M., Lane, Steven W., Schoumacher, Marie, Banquet, Sébastien, Majewski, Ian J., Strasser, Andreas, Roberts, Andrew W., Huang, David C.S., Brown, Fiona C., Kelly, Gemma L., Wei, Andrew H.

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Fascin, a novel target of β-catenin-TCF signaling, is expressed at the invasive front of human colon cancer von VIGNJEVIC, Danijela, SCHOUMACHER, Marie, GAVERT, Nancy, JANSSEN, Klaus-Peter, JIH, Gloria, LAE, Marick, LOUVARD, Daniel, BEN-ZE'EV, Avri, ROBINE, Sylvie

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Uveal melanoma cells are resistant to EZH2 inhibition regardless of BAP1 status von Schoumacher, Marie, Le Corre, Stéphanie, Houy, Alexandre, Mulugeta, Eskeatnaf, Stern, Marc-Henri, Roman-Roman, Sergio, Margueron, Raphaël

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Cytoskeleton networks in basement membrane transmigration von Schoumacher, Marie, Louvard, Daniel, Vignjevic, Danijela

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Upcoming translational challenges for uveal melanoma von Amirouchene-Angelozzi, Nabil, Schoumacher, Marie, Stern, Marc-Henri, Cassoux, Nathalie, Desjardins, Laurence, Piperno-Neumann, Sophie, Lantz, Olivier, Roman-Roman, Sergio

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Abstract 1276: Identification of S65487/VOB560 as a potent and selective intravenous 2nd-generation BCL-2 inhibitor active in wild-type and clinical mutants resistant to Venetoclax von Tiran, Arnaud Le, Claperon, Audrey, Davidson, James, Starck, Jérôme-Benoit, Diguarher, Thierry Le, Chanrion, Maïa, Mistry, Prakash, Wang, Youzhen, Monceau, Elodie, Bernhardt, Fabienne, Rocchetti, Francesca, Lysiak-Auvity, Gaelle, Chen, Ijen, Daniels, Zoe, Pedder, Chris, Fallowfield, Mandy, Henlin, Jean-Michel, Fejes, Imre, Tatai, Janos, Nyerges, Miklos, Durand, Didier, Zarka, Marion, Sanghavi, Sneha, Girard, Anne-Marie, Schoumacher, Marie, Kraus-Berthier, Laurence, Newcombe, Rick, Halilovic, Ensar, Banquet, Sébastien, Rupin, Alain, Maacke, Heiko, Murray, James, Morris, Erick, Hofmann, Francesco, Colland, Frédéric, Geneste, Olivier

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Acquired Mutations in BAX Confer Resistance to BH3 Mimetics in Acute Myeloid Leukemia von Moujalled, Donia M, Brown, Fiona C, Pomilio, Giovanna, Anstee, Natasha S, Litalien, Veronique, Thompson, Ella R, Morley, Thomas, MacRaild, Sarah, Chua, Chong C, Banquet, SéBastien, Chanrion, Maia, Maragno, Ana-Leticia, Schoumacher, Marie, Herold, Marco J, Lessene, Guillaume, Geneste, Olivier, Huang, David C.S., Roberts, Andrew W, Blombery, Piers, Wei, Andrew

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Abstract 257: Targeting AML through apoptosis activation using Bcl-2/Mcl-1 or Bcl-2/Hdm2 inhibitor combination therapies von Wang, Youzhen, Qui, Shumei, Sanghavi, Sneha, Mulford, Iain, Lysiak, Gaëlle, Chanrion, Maïa, Mistry, Prakash, Pfaar, Ulrike, Schoumacher, Marie, Claperon, Audrey, Kraus-Berthier, Laurence, Banquet, Sébastien, Derreal, Alix, Fabre, Claire, Maacke, Heiko, Colland, Frédéric, Geneste, Olivier, Morris, Erick, Halilovic, Ensar

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The mTOR inhibitor Everolimus synergizes with the PI3K inhibitor GDC0941 to enhance anti-tumor efficacy in uveal melanoma von Amirouchene-Angelozzi, Nabil, Frisch-Dit-Leitz, Estelle, Carita, Guillaume, Dahmani, Ahmed, Raymondie, Chloé, Liot, Géraldine, Gentien, David, Némati, Fariba, Decaudin, Didier, Roman-Roman, Sergio, Schoumacher, Marie

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Dual inhibition of protein kinase C and p53-MDM2 or PKC and mTORC1 are novel efficient therapeutic approaches for uveal melanoma von Carita, Guillaume, Frisch-Dit-Leitz, Estelle, Dahmani, Ahmed, Raymondie, Chloé, Cassoux, Nathalie, Piperno-Neumann, Sophie, Némati, Fariba, Laurent, Cécile, De Koning, Leanne, Halilovic, Ensar, Jeay, Sebastien, Wylie, Andrew, Emery, Caroline, Roman-Roman, Sergio, Schoumacher, Marie, Decaudin, Didier

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Combined BCL-2 and HDAC Targeting Has Potent and TP53 Independent Activity in AML von Salmon, Jessica M, Pomilio, Giovanna, Moujalled, Donia M, Macraild, Sarah, Teh, Charis E, Riajl, Sewa, Ivey, Adam, Teh, Tse-Chieh, Ekert, Paul G, Kraus-Berthier, Laurence, Kloos, Ioana, Schoumacher, Marie, Gray, Daniel, Wei, Andrew H

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