Embryonic and tumorigenic pathways converge via Nodal signaling: role in melanoma aggressiveness von Hendrix, Mary J C, Topczewska, Jolanta M, Postovit, Lynne-Marie, Margaryan, Naira V, Sam, Anthony, Hess, Angela R, Wheaton, William W, Nickoloff, Brian J, Topczewski, Jacek

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Regulation of the embryonic morphogen Nodal by Notch4 facilitates manifestation of the aggressive melanoma phenotype von Hardy, Katharine M, Kirschmann, Dawn A, Seftor, Elisabeth A, Margaryan, Naira V, Postovit, Lynne-Marie, Strizzi, Luigi, Hendrix, Mary J C

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Human Embryonic Stem Cell Microenvironment Suppresses the Tumorigenic Phenotype of Aggressive Cancer Cells von Postovit, Lynne-Marie, Margaryan, Naira V., Seftor, Elisabeth A., Kirschmann, Dawn A., Lipavsky, Alina, Wheaton, William W., Abbott, Daniel E., Seftor, Richard E. B., Hendrix, Mary J. C.

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Inorganic polyphosphate as an energy source in tumorigenesis von Boyineni, Jerusha, Sredni, Simone T, Margaryan, Naira V, Demirkhanyan, Lusine, Tye, Michael, Johnson, Robert, Gonzalez-Nilo, Fernando, Hendrix, Mary J C, Pavlov, Evgeny, Soares, Marcelo B, Zakharian, Eleonora, Malchenko, Sergey

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Cleavage of Histone 3 by Cathepsin D in the involuting mammary gland von Khalkhali-Ellis, Zhila, Goossens, William, Margaryan, Naira V, Hendrix, Mary J C

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Reprogramming Metastatic Melanoma Cells to Assume a Neural Crest Cell-Like Phenotype in an Embryonic Microenvironment von Kulesa, Paul M., Kasemeier-Kulesa, Jennifer C., Teddy, Jessica M., Margaryan, Naira V., Seftor, Elisabeth A., Seftor, Richard E. B., Hendrix, Mary J. C.

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Stabilization of HIF-1α and HIF-2α, up-regulation of MYCC and accumulation of stabilized p53 constitute hallmarks of CNS-PNET animal model von Malchenko, Sergey, Sredni, Simone Treiger, Bi, Yingtao, Margaryan, Naira V, Boyineni, Jerusha, Mohanam, Indra, Tomita, Tadanori, Davuluri, Ramana V, Soares, Marcelo B

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Potential for the embryonic morphogen Nodal as a prognostic and predictive biomarker in breast cancer von Strizzi, Luigi, Hardy, Katharine M, Margaryan, Naira V, Hillman, David W, Seftor, Elisabeth A, Chen, Beiyun, Geiger, Xochiquetzal J, Thompson, E Aubrey, Lingle, Wilma L, Andorfer, Cathy A, Perez, Edith A, Hendrix, Mary J C

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A mouse model of human primitive neuroectodermal tumors resulting from microenvironmentally-driven malignant transformation of orthotopically transplanted radial glial cells von Malchenko, Sergey, Sredni, Simone Treiger, Hashimoto, Hitoshi, Kasai, Atsushi, Nagayasu, Kazuki, Xie, Jianping, Margaryan, Naira V, Seiriki, Kaoru, Lulla, Rishi R, Seftor, Richard E B, Pachman, Lauren M, Meltzer, Herbert Y, Hendrix, Mary J C, Soares, Marcelo B

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Interferon Regulatory Factor 6 Promotes Cell Cycle Arrest and Is Regulated by the Proteasome in a Cell Cycle-Dependent Manner von Bailey, Caleb M., Abbott, Daniel E., Margaryan, Naira V., Khalkhali-Ellis, Zhila, Hendrix, Mary J. C.

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Focal adhesion kinase promotes the aggressive melanoma phenotype von HESS, Angela R, POSTOVIT, Lynne-Marie, MARGARYAN, Naira V, SEFTOR, Elisabeth A, SCHNEIDER, Galen B, SEFTOR, Richard E. B, NICKOLOFF, Brian J, HENDRIX, Mary J. C

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EphA2 as a promoter of melanoma tumorigenicity von Margaryan, Naira V., Strizzi, Luigi, Abbott, Daniel E, Seftor, Elisabeth A, Rao, M Sambasiva, Hendrix, Mary J, Hess, Angela

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Melanocytes Affect Nodal Expression and Signaling in Melanoma Cells: A Lesson from Pediatric Large Congenital Melanocytic Nevi von Margaryan, Naira V, Gilgur, Alina, Seftor, Elisabeth A, Purnell, Chad, Arva, Nicoleta C, Gosain, Arun K, Hendrix, Mary J C, Strizzi, Luigi

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Hypoxia/reoxygenation: A dynamic regulator of lysyl oxidase-facilitated breast cancer migration von Postovit, Lynne-Marie, Abbott, Daniel E., Payne, Stacey L., Wheaton, William W., Margaryan, Naira V., Sullivan, Richard, Jansen, Matthias K., Csiszar, Katalin, Hendrix, Mary J.C., Kirschmann, Dawn A.

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Tumor Cell Vasculogenic Mimicry: From Controversy to Therapeutic Promise von SEFTOR, Richard E. B, HESS, Angela R, SEFTOR, Elisabeth A, KIRSCHMANN, Dawn A, HARDY, Katharine M, MARGARYAN, Naira V, HENDRIX, Mary J. C

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Grainyhead-like-2, an epithelial master programmer, promotes interferon induction and suppresses breast cancer recurrence von MacFawn, Ian, Farris, Joshua, Pifer, Phillip, Margaryan, Naira V., Akhter, Halima, Wang, Lei, Dziadowicz, Sebastian, Denvir, James, Hu, Gangqing, Frisch, Steven M.

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Nuclear Aurora-A kinase-induced hypoxia signaling drives early dissemination and metastasis in breast cancer: implications for detection of metastatic tumors von Whately, Kristina M., Voronkova, Maria A., Maskey, Abha, Gandhi, Jasleen, Loskutov, Juergen, Choi, Hyeran, Yanardag, Sila, Chen, Dongquan, Wen, Sijin, Margaryan, Naira V., Smolkin, Matthew B., Purazo, Marc L., Hu, Gangqing, Pugacheva, Elena N.

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p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas von Qin, Jian-Zhong, Stennett, Lawrence, Bacon, Patricia, Bodner, Barbara, Hendrix, Mary J C, Seftor, Richard E B, Seftor, Elisabeth A, Margaryan, Naira V, Pollock, Pamela M, Curtis, Amy, Trent, Jeffrey M, Bennett, Frank, Miele, Lucio, Nickoloff, Brian J

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LPA signaling is regulated through the primary cilium: a novel target in glioblastoma von Loskutov, Yuriy V., Griffin, Caryn L., Marinak, Kristina M., Bobko, Andrey, Margaryan, Naira V., Geldenhuys, Werner J., Sarkaria, Jann N., Pugacheva, Elena N.

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Reevaluating Cathepsin D as a biomarker for breast cancer: Serum activity levels versus histopathology von Abbott, Daniel E, Margaryan, Naira V, Jeruss, Jacqueline, Khan, Seema, Kaklamani, Virginia, Winchester, David J, Hansen, Nora, Rademaker, Alfred, Khalkhali-Ellis, Zhila, Hendrix, Mary J.C.

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