Alzheimer's disease pathology is attenuated in a CD38-deficient mouse model von Blacher, Eran, Dadali, Tulin, Bespalko, Alina, Haupenthal, Viola J., Grimm, Marcus O. W., Hartmann, Tobias, Lund, Frances E., Stein, Reuven, Levy, Ayelet

Volltext

Plasmalogen synthesis is regulated via alkyl-dihydroxyacetonephosphate-synthase by amyloid precursor protein processing and is affected in Alzheimer's disease von Grimm, Marcus O.W, Kuchenbecker, Johanna, Rothhaar, Tatjana L, Grösgen, Sven, Hundsdörfer, Benjamin, Burg, Verena K, Friess, Petra, Müller, Ulrike, Grimm, Heike S, Riemenschneider, Mathias, Hartmann, Tobias

Volltext

The role of APP proteolytic processing in lipid metabolism von Grimm, Marcus O. W., Rothhaar, Tatjana L., Hartmann, Tobias

Volltext

Shotgun lipidomics of liver and brain tissue of Alzheimer’s disease model mice treated with acitretin von Lauer, Anna A., Janitschke, Daniel, dos Santos Guilherme, Malena, Nguyen, Vu Thu Thuy, Bachmann, Cornel M., Qiao, Sen, Schrul, Bianca, Boehm, Ulrich, Grimm, Heike S., Hartmann, Tobias, Endres, Kristina, Grimm, Marcus O. W.

Volltext

Alzheimer's disease: the lipid connection von Hartmann, Tobias, Kuchenbecker, Johannna, Grimm, Marcus O.W

Volltext

Regulation of cholesterol and sphingomyelin metabolism by amyloid-β and presenilin von Grimm, Marcus O. W., Grimm, Heike S., Pätzold, Andreas J., Zinser, Eva G., Halonen, Riikka, Duering, Marco, Tschäpe, Jakob-A., Strooper, Bart De, Müller, Ulrike, Shen, Jie, Hartmann, Tobias

Volltext

Sphingomyelin Synthase 1 Is Essential for Male Fertility in Mice von Wittmann, Anke, Grimm, Marcus O W, Scherthan, Harry, Horsch, Marion, Beckers, Johannes, Fuchs, Helmut, Gailus-Durner, Valerie, Hrabě de Angelis, Martin, Ford, Steven J, Burton, Neal C, Razansky, Daniel, Trümbach, Dietrich, Aichler, Michaela, Walch, Axel Karl, Calzada-Wack, Julia, Neff, Frauke, Wurst, Wolfgang, Hartmann, Tobias, Floss, Thomas

Volltext

Omega-3 fatty acids, lipids, and apoE lipidation in Alzheimer's disease: a rationale for multi-nutrient dementia prevention von Grimm, Marcus O.W., Michaelson, Daniel M., Hartmann, Tobias

Volltext

The Impact of Cholesterol, DHA, and Sphingolipids on Alzheimer’s Disease von Grimm, Heike S., Lehmann, Johannes, Zimmer, Valerie C., Grimm, Marcus O. W., Hartmann, Tobias

Volltext

Amyloid precursor protein (APP) mediated regulation of ganglioside homeostasis linking Alzheimer's disease pathology with ganglioside metabolism von Grimm, Marcus O W, Zinser, Eva G, Grösgen, Sven, Hundsdörfer, Benjamin, Rothhaar, Tatjana L, Burg, Verena K, Kaestner, Lars, Bayer, Thomas A, Lipp, Peter, Müller, Ulrike, Grimm, Heike S, Hartmann, Tobias

Volltext

APP Function and Lipids: A Bidirectional Link von Grimm, Marcus O W, Mett, Janine, Grimm, Heike S, Hartmann, Tobias

Volltext

Plant sterols the better cholesterol in Alzheimer's disease? A mechanistical study von Burg, Verena K, Grimm, Heike S, Rothhaar, Tatjana L, Grösgen, Sven, Hundsdörfer, Benjamin, Haupenthal, Viola J, Zimmer, Valerie C, Mett, Janine, Weingärtner, Oliver, Laufs, Ulrich, Broersen, Laus M, Tanila, Heikki, Vanmierlo, Tim, Lütjohann, Dieter, Hartmann, Tobias, Grimm, Marcus O W

Volltext

From brain to food: Analysis of phosphatidylcholins, lyso-phosphatidylcholins and phosphatidylcholin–plasmalogens derivates in Alzheimer's disease human post mortem brains and mice... von Grimm, Marcus O.W., Grösgen, Sven, Riemenschneider, Matthias, Tanila, Heikki, Grimm, Heike S., Hartmann, Tobias

Volltext

The impact of capsaicinoids on APP processing in Alzheimer’s disease in SH-SY5Y cells von Grimm, Marcus O. W., Blümel, Tamara, Lauer, Anna A., Janitschke, Daniel, Stahlmann, Christoph, Mett, Janine, Haupenthal, Viola J., Miederer, Anna-Maria, Niemeyer, Barbara A., Grimm, Heike S., Hartmann, Tobias

Volltext

Trans fatty acids enhance amyloidogenic processing of the Alzheimer amyloid precursor protein (APP) von Grimm, Marcus O.W, Rothhaar, Tatjana L, Grösgen, Sven, Burg, Verena K, Hundsdörfer, Benjamin, Haupenthal, Viola J, Friess, Petra, Kins, Stefan, Grimm, Heike S, Hartmann, Tobias

Volltext

Oxidized Docosahexaenoic Acid Species and Lipid Peroxidation Products Increase Amyloidogenic Amyloid Precursor Protein Processing von Grimm, Marcus O.W., Haupenthal, Viola J., Mett, Janine, Stahlmann, Christoph P., Blümel, Tamara, Mylonas, Nadine T., Endres, Kristina, Grimm, Heike S., Hartmann, Tobias

Volltext

Independent Inhibition of Alzheimer Disease β- and γ-Secretase Cleavage by Lowered Cholesterol Levels von Grimm, Marcus O.W., Grimm, Heike S., Tomic, Inge, Beyreuther, Konrad, Hartmann, Tobias, Bergmann, Christine

Volltext

Medium-Chain Length Fatty Acids Enhance Aβ Degradation by Affecting Insulin-Degrading Enzyme von Mett, Janine, Lauer, Anna A, Janitschke, Daniel, Griebsch, Lea V, Theiss, Elena L, Grimm, Heike S, Koivisto, Hennariikka, Tanila, Heikki, Hartmann, Tobias, Grimm, Marcus O W

Volltext

The Impact of Vitamin E and Other Fat-Soluble Vitamins on Alzheimer's Disease von Grimm, Marcus O W, Mett, Janine, Hartmann, Tobias

Volltext

Plasmalogens Inhibit APP Processing by Directly Affecting γ-Secretase Activity in Alzheimer’s Disease von Grimm, Heike S., Hartmann, Tobias, Grimm, Marcus O. W., Rothhaar, Tatjana L., Riemenschneider, Matthias, Mett, Janine, Hundsdörfer, Benjamin, Grösgen, Sven, Haupenthal, Viola J., Burg, Verena K.

Volltext