Genomic instability, inflammatory signaling and response to cancer immunotherapy von Chen, Mengting, Linstra, Renske, van Vugt, Marcel A.T.M.

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BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity von Heijink, Anne Margriet, Talens, Francien, Jae, Lucas T., van Gijn, Stephanie E., Fehrmann, Rudolf S. N., Brummelkamp, Thijn R., van Vugt, Marcel A. T. M.

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cGAS–STING drives the IL-6-dependent survival of chromosomally instable cancers von Hong, Christy, Schubert, Michael, Tijhuis, Andréa E., Requesens, Marta, Roorda, Maurits, van den Brink, Anouk, Ruiz, Lorena Andrade, Bakker, Petra L., van der Sluis, Tineke, Pieters, Wietske, Chen, Mengting, Wardenaar, René, van der Vegt, Bert, Spierings, Diana C. J., de Bruyn, Marco, van Vugt, Marcel A. T. M., Foijer, Floris

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POLQ to the rescue for double-strand break repair during mitosis von van Vugt, Marcel A. T. M., Tijsterman, Marcel

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RIF1 promotes replication fork protection and efficient restart to maintain genome stability von Mukherjee, Chirantani, Tripathi, Vivek, Manolika, Eleni Maria, Heijink, Anne Margriet, Ricci, Giulia, Merzouk, Sarra, de Boer, H. Rudolf, Demmers, Jeroen, van Vugt, Marcel A. T. M., Ray Chaudhuri, Arnab

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DNA Damage Activates a Spatially Distinct Late Cytoplasmic Cell-Cycle Checkpoint Network Controlled by MK2-Mediated RNA Stabilization von Reinhardt, H. Christian, Hasskamp, Pia, Schmedding, Ingolf, Morandell, Sandra, van Vugt, Marcel A.T.M., Wang, XiaoZhe, Linding, Rune, Ong, Shao-En, Weaver, David, Carr, Steven A., Yaffe, Michael B.

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Transcriptional effects of copy number alterations in a large set of human cancers von Bhattacharya, Arkajyoti, Bense, Rico D., Urzúa-Traslaviña, Carlos G., de Vries, Elisabeth G. E., van Vugt, Marcel A. T. M., Fehrmann, Rudolf S. N.

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Gene expression analysis identifies global gene dosage sensitivity in cancer von Fehrmann, Rudolf S N, Karjalainen, Juha M, Krajewska, Małgorzata, Westra, Harm-Jan, Maloney, David, Simeonov, Anton, Pers, Tune H, Hirschhorn, Joel N, Jansen, Ritsert C, Schultes, Erik A, van Haagen, Herman H H B M, de Vries, Elisabeth G E, te Meerman, Gerard J, Wijmenga, Cisca, van Vugt, Marcel A T M, Franke, Lude

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Relevance of Tumor-Infiltrating Immune Cell Composition and Functionality for Disease Outcome in Breast Cancer von Bense, Rico D, Sotiriou, Christos, Piccart-Gebhart, Martine J, Haanen, John B A G, van Vugt, Marcel A T M, de Vries, Elisabeth G E, Schröder, Carolien P, Fehrmann, Rudolf S N

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FIRRM and FIGNL1: partners in the regulation of homologous recombination von Tsaridou, Stavroula, van Vugt, Marcel A.T.M.

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Shaping the BRCAness mutational landscape by alternative double-strand break repair, replication stress and mitotic aberrancies von Stok, Colin, Kok, Yannick P, van den Tempel, Nathalie, van Vugt, Marcel A T M

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Sister chromatid exchanges induced by perturbed replication can form independently of BRCA1, BRCA2 and RAD51 von Heijink, Anne Margriet, Stok, Colin, Porubsky, David, Manolika, Eleni Maria, de Kanter, Jurrian K., Kok, Yannick P., Everts, Marieke, de Boer, H. Rudolf, Audrey, Anastasia, Bakker, Femke J., Wierenga, Elles, Tijsterman, Marcel, Guryev, Victor, Spierings, Diana C. J., Knipscheer, Puck, van Boxtel, Ruben, Ray Chaudhuri, Arnab, Lansdorp, Peter M., van Vugt, Marcel A. T. M.

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An mRNA expression-based signature for oncogene-induced replication-stress von Guerrero Llobet, Sergi, Bhattacharya, Arkajyoti, Everts, Marieke, Kok, Klaas, van der Vegt, Bert, Fehrmann, Rudolf S. N., van Vugt, Marcel A. T. M.

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MYC promotes immune-suppression in triple-negative breast cancer via inhibition of interferon signaling von Zimmerli, Dario, Brambillasca, Chiara S., Talens, Francien, Bhin, Jinhyuk, Linstra, Renske, Romanens, Lou, Bhattacharya, Arkajyoti, Joosten, Stacey E. P., Da Silva, Ana Moises, Padrao, Nuno, Wellenstein, Max D., Kersten, Kelly, de Boo, Mart, Roorda, Maurits, Henneman, Linda, de Bruijn, Roebi, Annunziato, Stefano, van der Burg, Eline, Drenth, Anne Paulien, Lutz, Catrin, Endres, Theresa, van de Ven, Marieke, Eilers, Martin, Wessels, Lodewyk, de Visser, Karin E., Zwart, Wilbert, Fehrmann, Rudolf S. N., van Vugt, Marcel A. T. M., Jonkers, Jos

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Premature mitotic entry induced by ATR inhibition potentiates olaparib inhibition‐mediated genomic instability, inflammatory signaling, and cytotoxicity in BRCA2‐deficient cancer c... von Schoonen, Pepijn M., Kok, Yannick P., Wierenga, Elles, Bakker, Bjorn, Foijer, Floris, Spierings, Diana C. J., Vugt, Marcel A. T. M.

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Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells von Schoonen, Pepijn M., Talens, Francien, Stok, Colin, Gogola, Ewa, Heijink, Anne Margriet, Bouwman, Peter, Foijer, Floris, Tarsounas, Madalena, Blatter, Sohvi, Jonkers, Jos, Rottenberg, Sven, van Vugt, Marcel A. T. M.

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Inflammatory signaling in genomically instable cancers von Talens, Francien, Van Vugt, Marcel A.T.M.

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Improving gene function predictions using independent transcriptional components von Urzúa-Traslaviña, Carlos G., Leeuwenburgh, Vincent C., Bhattacharya, Arkajyoti, Loipfinger, Stefan, van Vugt, Marcel A. T. M., de Vries, Elisabeth G. E., Fehrmann, Rudolf S. N.

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Testicular cancer: Determinants of cisplatin sensitivity and novel therapeutic opportunities von de Vries, Gerda, Rosas-Plaza, Ximena, van Vugt, Marcel A.T.M., Gietema, Jourik A., de Jong, Steven

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TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells von van Gijn, Stephanie E., Wierenga, Elles, van den Tempel, Nathalie, Kok, Yannick P., Heijink, Anne Margriet, Spierings, Diana C. J., Foijer, Floris, van Vugt, Marcel A. T. M., Fehrmann, Rudolf S. N.

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