TREM-1 and its potential ligands in non-infectious diseases: from biology to clinical perspectives von Tammaro, Alessandra, Derive, Marc, Gibot, Sebastien, Leemans, Jaklien C, Florquin, Sandrine, Dessing, Mark C

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Potentiation of NETs release is novel characteristic of TREM-1 activation and the pharmacological inhibition of TREM-1 could prevent from the deleterious consequences of NETs relea... von Boufenzer, Amir, Carrasco, Kevin, Jolly, Lucie, Brustolin, Benjamin, Di-Pillo, Elisa, Derive, Marc, Gibot, Sébastien

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TREM-1 orchestrates angiotensin II-induced monocyte trafficking and promotes experimental abdominal aortic aneurysm von Vandestienne, Marie, Zhang, Yujiao, Santos-Zas, Icia, Al-Rifai, Rida, Joffre, Jeremie, Giraud, Andreas, Laurans, Ludivine, Esposito, Bruno, Pinet, Florence, Bruneval, Patrick, Raffort, Juliette, Lareyre, Fabien, Vilar, Jose, Boufenzer, Amir, Guyonnet, Lea, Guerin, Coralie, Clauser, Eric, Silvestre, Jean-Sébastien, Lang, Sylvie, Soulat-Dufour, Laurie, Tedgui, Alain, Mallat, Ziad, Taleb, Soraya, Boissonnas, Alexandre, Derive, Marc, Chinetti, Giulia, Ait-Oufella, Hafid

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sTREM-1 is a specific biomarker of TREM-1 pathway activation von Jolly, Lucie, Carrasco, Kévin, Salcedo-Magguilli, Margarita, Garaud, Jean-Jacques, Lambden, Simon, van der Poll, Tom, Mebazaa, Alexandre, Laterre, Pierre-François, Gibot, Sebastien, Boufenzer, Amir, Derive, Marc

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Nangibotide in patients with septic shock: a Phase 2a randomized controlled clinical trial von François, Bruno, Wittebole, Xavier, Ferrer, Ricard, Mira, Jean-Paul, Dugernier, Thierry, Gibot, Sébastien, Derive, Marc, Olivier, Aurélie, Cuvier, Valérie, Witte, Stephan, Pickkers, Peter, Vandenhende, François, Garaud, Jean-Jacques, Sánchez, Miguel, Salcedo-Magguilli, Margarita, Laterre, Pierre-François

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Triggering Receptor Expressed on Myeloid Cells-1 Inhibitor Targeted to Endothelium Decreases Cell Activation von Gibot, Sébastien, Jolly, Lucie, Lemarié, Jérémie, Carrasco, Kevin, Derive, Marc, Boufenzer, Amir

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Oxidative stress-induced endothelial dysfunction and decreased vascular nitric oxide in COVID-19 patients von Montiel, Virginie, Lobysheva, Irina, Gérard, Ludovic, Vermeersch, Marjorie, Perez-Morga, David, Castelein, Thomas, Mesland, Jean-Baptiste, Hantson, Philippe, Collienne, Christine, Gruson, Damien, van Dievoet, Marie-Astrid, Persu, Alexandre, Beauloye, Christophe, Dechamps, Mélanie, Belkhir, Leïla, Robert, Annie, Derive, Marc, Laterre, Pierre-François, Danser, A.H.J, Wittebole, Xavier, Balligand, Jean-Luc

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The Triggering Receptor Expressed on Myeloid cells-1: A new player during acute myocardial infarction von Jérémie, Lemarié, Amir, Boufenzer, Marc, Derive, Sébastien, Gibot

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Triggering Receptors Expressed on Myeloid Cells 1 : Our New Partner in Human Oncology? von Muller, Marie, Haghnejad, Vincent, Lopez, Anthony, Tiotiu, Angelica, Renaud, Stéphane, Derive, Marc, Bronowicki, Jean-Pierre

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THBS1+ myeloid cells expand in SLD hepatocellular carcinoma and contribute to immunosuppression and unfavorable prognosis through TREM1 von Giraud, Julie, Chalopin, Domitille, Ramel, Eloïse, Boyer, Thomas, Zouine, Atika, Derieppe, Marie-Alix, Larmonier, Nicolas, Adotevi, Olivier, Le Bail, Brigitte, Blanc, Jean-Frédéric, Laurent, Christophe, Chiche, Laurence, Derive, Marc, Nikolski, Macha, Saleh, Maya

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Soluble TREM-like transcript-1 regulates leukocyte activation and controls microbial sepsis von Derive, Marc, Bouazza, Youcef, Sennoun, Nacira, Marchionni, Sandra, Quigley, Laura, Washington, Valance, Massin, Frédéric, Max, Jean-Pierre, Ford, Jill, Alauzet, Corentine, Levy, Bruno, McVicar, Daniel W, Gibot, Sébastien

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Dexamethasone Modulates the Cytokine Response but Not COVID-19-Induced Coagulopathy in Critically Ill von Dechamps, Mélanie, De Poortere, Julien, Octave, Marie, Ginion, Audrey, Robaux, Valentine, Pirotton, Laurence, Bodart, Julie, Gruson, Damien, Van Dievoet, Marie-Astrid, Douxfils, Jonathan, Haguet, Hélène, Morimont, Laure, Derive, Marc, Jolly, Lucie, Bertrand, Luc, Laterre, Pierre-François, Horman, Sandrine, Beauloye, Christophe

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Triggering receptor expressed on myeloid cells-1 deletion in mice attenuates high-fat diet-induced obesity von Brustolin, Benjamin, Touly, Nina, Maillefer, Marine, Parisot, Lola, Di Pillo, Elisa, Derive, Marc, Gibot, Sébastien

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TREM-1 SNP rs2234246 regulates TREM-1 protein and mRNA levels and is associated with plasma levels of L-selectin von Aldasoro Arguinano, Alex-Ander, Dadé, Sébastien, Stathopoulou, Maria, Derive, Marc, Coumba Ndiaye, Ndeye, Xie, Ting, Masson, Christine, Gibot, Sébastien, Visvikis-Siest, Sophie

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Rationale and protocol for the efficacy, safety and tolerability of nangibotide in patients with septic shock (ASTONISH) phase IIb randomised controlled trial von Francois, Bruno, Lambden, Simon, Gibot, Sebastien, Derive, Marc, Olivier, Aurelie, Cuvier, Valerie, Witte, Stephan, Grouin, Jean-Marie, Garaud, Jean Jacques, Salcedo-Magguilli, Margarita, Levy, Mitchell, Laterre, Pierre-François

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Soluble TREM-1 plasma concentration predicts poor outcome in COVID-19 patients von Gibot, Sébastien, Lafon, Thomas, Jacquin, Laurent, Lefevre, Benjamin, Kimmoun, Antoine, Guillaumot, Anne, Losser, Marie-Reine, Douplat, Marion, Argaud, Laurent, De Ciancio, Guillaume, Jolly, Lucie, Touly, Nina, Derive, Marc, Malaplate, Catherine, Luc, Amandine, Baumann, Cédric, François, Bruno

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Targeted endothelial gene deletion of triggering receptor expressed on myeloid cells-1 protects mice during septic shock von Jolly, Lucie, Carrasco, Kevin, Derive, Marc, Lemarié, Jérémie, Boufenzer, Amir, Gibot, Sébastien

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Persistently Elevated Soluble Triggering Receptor Expressed on Myeloid Cells 1 and Decreased Monocyte Human Leucocyte Antigen DR Expression Are Associated With Nosocomial Infection... von Venet, Matthieu, Bidar, Frank, Derive, Marc, Delwarde, Benjamin, Monard, Céline, Hengy, Baptiste, Jolly, Lucie, Rimmelé, Thomas, Lukaszewicz, Anne-Claire, Monneret, Guillaume, Venet, Fabienne

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Inflammation-Induced Coagulopathy Substantially Differs Between COVID-19 and Septic Shock: A Prospective Observational Study von Dechamps, Mélanie, De Poortere, Julien, Martin, Manon, Gatto, Laurent, Daumerie, Aurélie, Bouzin, Caroline, Octave, Marie, Ginion, Audrey, Robaux, Valentine, Pirotton, Laurence, Bodart, Julie, Gerard, Ludovic, Montiel, Virginie, Campion, Alessandro, Gruson, Damien, Van Dievoet, Marie-Astrid, Douxfils, Jonathan, Haguet, Hélène, Morimont, Laure, Derive, Marc, Jolly, Lucie, Bertrand, Luc, Dumoutier, Laure, Castanares-Zapatero, Diego, Laterre, Pierre-François, Horman, Sandrine, Beauloye, Christophe

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Effects of the TREM 1 pathway modulation during hemorrhagic shock in rats von Gibot, Sébastien, Massin, Frédéric, Alauzet, Corentine, Derive, Marc, Montemont, Chantal, Collin, Solene, Fremont, Sophie, Levy, Bruno

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