A substrate binding model for the KEOPS tRNA modifying complex von Beenstock, Jonah, Ona, Samara Mishelle, Porat, Jennifer, Orlicky, Stephen, Wan, Leo C. K., Ceccarelli, Derek F., Maisonneuve, Pierre, Szilard, Rachel K., Yin, Zhe, Setiaputra, Dheva, Mao, Daniel Y. L., Khan, Morgan, Raval, Shaunak, Schriemer, David C., Bayfield, Mark A., Durocher, Daniel, Sicheri, Frank

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Dimeric Structure of Pseudokinase RNase L Bound to 2-5A Reveals a Basis for Interferon-Induced Antiviral Activity von Huang, Hao, Zeqiraj, Elton, Dong, Beihua, Jha, Babal Kant, Duffy, Nicole M., Orlicky, Stephen, Thevakumaran, Neroshan, Talukdar, Manisha, Pillon, Monica C., Ceccarelli, Derek F., Wan, Leo C.K., Juang, Yu-Chi, Mao, Daniel Y.L., Gaughan, Christina, Brinton, Margo A., Perelygin, Andrey A., Kourinov, Igor, Guarné, Alba, Silverman, Robert H., Sicheri, Frank

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CUL7 is a novel antiapoptotic oncogene von KIM, Sam S, SHAGO, Mary, JURISICA, Igor, ARROSMITH, Cheryl H, PENN, Linda Z, KAUSTOV, Lilia, BOUTROS, Paul C, CLENDENING, James W, YI SHENG, TRENTIN, Grace A, BARSYTE-LOVEJOY, Dalia, MAO, Daniel Y. L, KAY, Robert

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Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system von Wan, Leo C K, Mao, Daniel Y L, Neculai, Dante, Strecker, Jonathan, Chiovitti, David, Kurinov, Igor, Poda, Gennadiy, Thevakumaran, Neroshan, Yuan, Fang, Szilard, Rachel K, Lissina, Elena, Nislow, Corey, Caudy, Amy A, Durocher, Daniel, Sicheri, Frank

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Functional analysis of the N-terminal domain of the Myc oncoprotein von OSTER, Sara K, MAO, Daniel Y. L, KENNEDY, James, PENN, Linda Z

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Inhibitors that stabilize a closed RAF kinase domain conformation induce dimerization von Lavoie, Hugo, Thevakumaran, Neroshan, Gavory, Gwenaëlle, Li, John J, Padeganeh, Abbas, Guiral, Sébastien, Duchaine, Jean, Mao, Daniel Y L, Bouvier, Michel, Sicheri, Frank, Therrien, Marc

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Engineered antigen‐binding fragments for enhanced crystallization of antibody:antigen complexes von Bruce, Heather A., Singer, Alexander U., Filippova, Ekaterina V., Blazer, Levi L., Adams, Jarrett J., Enderle, Leonie, Ben‐David, Moshe, Radley, Elizabeth H., Mao, Daniel Y. L., Pau, Victor, Orlicky, Stephen, Sicheri, Frank, Kurinov, Igor, Atwell, Shane, Kossiakoff, Anthony A., Sidhu, Sachdev S.

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c-Myc represses the proximal promoters of GADD45a and GADD153 by a post-RNA polymerase II recruitment mechanism von BARSYTE-LOVEJOY, Dalia, MAO, Daniel Y. L, PENN, Linda Z

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Promoter-binding and repression of PDGFRB by c-Myc are separable activities von Mao, Daniel Y. L., Barsyte-Lovejoy, Dalia, Ho, Cynthia S. W., Watson, John D., Stojanova, Angelina, Penn, Linda Z.

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Structural Basis for Auto-Inhibition of the NDR1 Kinase Domain by an Atypically Long Activation Segment von Xiong, Shawn, Lorenzen, Kristina, Couzens, Amber L., Templeton, Catherine M., Rajendran, Dushyandi, Mao, Daniel Y.L., Juang, Yu-Chi, Chiovitti, David, Kurinov, Igor, Guettler, Sebastian, Gingras, Anne-Claude, Sicheri, Frank

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Atomic Structure of the KEOPS Complex: An Ancient Protein Kinase-Containing Molecular Machine von Mao, Daniel Y.L., Neculai, Dante, Downey, Michael, Orlicky, Stephen, Haffani, Yosr Z., Ceccarelli, Derek F., Ho, Jenny S.L., Szilard, Rachel K., Zhang, Wei, Ho, Cynthia S., Wan, Leo, Fares, Christophe, Rumpel, Sigrun, Kurinov, Igor, Arrowsmith, Cheryl H., Durocher, Daniel, Sicheri, Frank

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OTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme Function von Juang, Yu-Chi, Landry, Marie-Claude, Sanches, Mario, Vittal, Vinayak, Leung, Charles C.Y., Ceccarelli, Derek F., Mateo, Abigail-Rachele F., Pruneda, Jonathan N., Mao, Daniel Y.L., Szilard, Rachel K., Orlicky, Stephen, Munro, Meagan, Brzovic, Peter S., Klevit, Rachel E., Sicheri, Frank, Durocher, Daniel

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p53-Dependent Transcriptional Repression of c-myc Is Required for G1 Cell Cycle Arrest von Ho, Jenny S. L., Ma, Weili, Mao, Daniel Y. L., Benchimol, Samuel

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“Unraveling the Tail” of How SRPK1 Phosphorylates ASF/SF2 von Mao, Daniel Y.L., Ceccarelli, Derek F., Sicheri, Frank

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p53-Dependent Transcriptional Repression of c-myc Is Required for G 1 Cell Cycle Arrest von Ho, Jenny S. L., Ma, Weili, Mao, Daniel Y. L., Benchimol, Samuel

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A Structure-based Model of the c-Myc/Bin1 Protein Interaction Shows Alternative Splicing of Bin1 and c-Myc Phosphorylation are Key Binding Determinants von Pineda-Lucena, Antonio, Ho, Cynthia S.W., Mao, Daniel Y.L., Sheng, Yi, Laister, Rob C., Muhandiram, Ranjith, Lu, Ying, Seet, Bruce T., Katz, Sigal, Szyperski, Thomas, Penn, Linda Z., Arrowsmith, Cheryl H.

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Analysis of Myc Bound Loci Identified by CpG Island Arrays Shows that Max Is Essential for Myc-Dependent Repression von Mao, Daniel Y.L., Watson, John D., Yan, Pearlly S., Barsyte-Lovejoy, Dalia, Khosravi, Fereshteh, Wong, W.Wei-Lynn, Farnham, Peggy J., Huang, Tim H.-M., Penn, Linda Z.

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p53-Dependent Transcriptional Repression of c-myc Is Required for G sub(1) Cell Cycle Arrest von Ho, Jenny SL, Ma, Weili, Mao, Daniel YL, Benchimol, Samuel

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Potential function for the Huntingtin protein as a scaffold for selective autophagy von Ochaba, Joseph, Lukacsovich, Tamás, Csikos, George, Zheng, Shuqiu, Margulis, Julia, Salazar, Lisa, Mao, Kai, Lau, Alice L., Yeung, Sylvia Y., Humbert, Sandrine, Saudou, Frédéric, Klionsky, Daniel J., Finkbeiner, Steven, Zeitlin, Scott O., Marsh, J. Lawrence, Housman, David E., Thompson, Leslie M., Steffan, Joan S.

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IL-11 is a crucial determinant of cardiovascular fibrosis von Schafer, Sebastian, Viswanathan, Sivakumar, Widjaja, Anissa A., Lim, Wei-Wen, Moreno-Moral, Aida, DeLaughter, Daniel M., Ng, Benjamin, Patone, Giannino, Chow, Kingsley, Khin, Ester, Tan, Jessie, Chothani, Sonia P., Ye, Lei, Rackham, Owen J. L., Ko, Nicole S. J., Sahib, Norliza E., Pua, Chee Jian, Zhen, Nicole T. G., Xie, Chen, Wang, Mao, Maatz, Henrike, Lim, Shiqi, Saar, Kathrin, Blachut, Susanne, Petretto, Enrico, Schmidt, Sabine, Putoczki, Tracy, Guimarães-Camboa, Nuno, Wakimoto, Hiroko, van Heesch, Sebastiaan, Sigmundsson, Kristmundur, Lim, See L., Soon, Jia L., Chao, Victor T. T., Chua, Yeow L., Tan, Teing E., Evans, Sylvia M., Loh, Yee J., Jamal, Muhammad H., Ong, Kim K., Chua, Kim C., Ong, Boon-Hean, Chakaramakkil, Mathew J., Seidman, Jonathan G., Seidman, Christine E., Hubner, Norbert, Sin, Kenny Y. K., Cook, Stuart A.

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