Endothelin-converting enzyme-1 increases in atherosclerotic mice: potential role of oxidized low density lipoproteins von Martínez-Miguel, Patricia, Raoch, Viviana, Zaragoza, Carlos, Valdivielso, Jose Manuel, Rodríguez-Puyol, Manuel, Rodríguez-Puyol, Diego, López-Ongil, Susana

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Chronic kidney disease induced by an adenine rich diet upregulates integrin linked kinase (ILK) and its depletion prevents the disease progression von de Frutos, Sergio, Luengo, Alicia, García-Jérez, Andrea, Hatem-Vaquero, Marco, Griera, Mercedes, O'Valle, Francisco, Rodríguez–Puyol, Manuel, Rodríguez–Puyol, Diego, Calleros, Laura

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A Computer‐Driven Scaffold‐Hopping Approach Generating New PTP1B Inhibitors from the Pyrrolo[1,2‐a]quinoxaline Core von García‐Marín, Javier, Griera, Mercedes, Alajarín, Ramón, Rodríguez‐Puyol, Manuel, Rodríguez‐Puyol, Diego, Vaquero, Juan J.

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Indoxyl sulfate- and P-cresol-induced monocyte adhesion and migration is mediated by integrin-linked kinase-dependent podosome formation von Campillo, Sofía, Bohorquez, Lourdes, Gutiérrez-Calabrés, Elena, García-Ayuso, Diego, Miguel, Verónica, Griera, Mercedes, Calle, Yolanda, de Frutos, Sergio, Rodríguez-Puyol, Manuel, Rodríguez-Puyol, Diego, Calleros, Laura

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H‐ras deletion protects against angiotensin II–induced arterial hypertension and cardiac remodeling through protein kinase G‐Iβ pathway activation von Martín‐Sánchez, Paloma, Luengo, Alicia, Griera, Mercedes, Orea, María Jesús, López‐Olañeta, Marina, Chiloeches, Antonio, Lara‐Pezzi, Enrique, Frutos, Sergio, Rodríguez–Puyol, Manuel, Calleros, Laura, Rodríguez–Puyol, Diego

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Pyrrolo[1,2‐a]quinoxalines: Insulin Mimetics that Exhibit Potent and Selective Inhibition against Protein Tyrosine Phosphatase 1B von García‐Marín, Javier, Griera, Mercedes, Sánchez‐Alonso, Patricia, Di Geronimo, Bruno, Mendicuti, Francisco, Rodríguez‐Puyol, Manuel, Alajarín, Ramón, Pascual‐Teresa, Beatriz, Vaquero, Juan J., Rodríguez‐Puyol, Diego

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Tripeptides as Integrin-Linked Kinase Modulating Agents Based on a Protein–Protein Interaction with α‑Parvin von Garcia-Marin, Javier, Griera-Merino, Mercedes, Matamoros-Recio, Alejandra, de Frutos, Sergio, Rodríguez-Puyol, Manuel, Alajarín, Ramón, Vaquero, Juan J, Rodríguez-Puyol, Diego

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Contribution of uremic toxins to the vascular fibrosis associated with chronic kidney disease von Hatem-Vaquero, Marco, de Frutos, Sergio, Luengo, Alicia, González Abajo, Alba, Griera, Mercedes, Rodríguez-Puyol, Manuel, Rodríguez-Puyol, Diego, Calleros, Laura

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Integrin‐linked kinase regulates tubular aquaporin‐2 content and intracellular location: a link between the extracellular matrix and water reabsorption von Cano‐Peñalver, Jose Luis, Griera, Mercedes, Serrano, Isabel, Rodríguez‐Puyol, Diego, Dedhar, Shoukat, Frutos, Sergio, Rodríguez‐Puyol, Manuel

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A Computer‐Driven Scaffold‐Hopping Approach Generating New PTP1B Inhibitors from the Pyrroloquinoxaline Core von Javier García‐Marín, Griera, Mercedes, Alajarín, Ramón, Manuel Rodríguez‐Puyol, Diego Rodríguez‐Puyol, Vaquero, Juan J

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Losartan-Antioxidant Hybrids: Novel Molecules for the Prevention of Hypertension-Induced Cardiovascular Damage von García, Gonzalo, Rodríguez-Puyol, Manuel, Alajarín, Ramón, Serrano, Isabel, Sánchez-Alonso, Patricia, Griera, Mercedes, Vaquero, Juan J, Rodríguez-Puyol, Diego, Álvarez-Builla, Julio, Díez-Marqués, María L

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Pyrrolo[1,2-a]quinoxal-5-inium salts and 4,5-dihydropyrrolo[1,2-a]quinoxalines: Synthesis, activity and computational docking for protein tyrosine phosphatase 1B von Sánchez-Alonso, Patricia, Griera, Mercedes, García-Marín, Javier, Rodríguez-Puyol, Manuel, Alajarín, Ramón, Vaquero, Juan J., Rodríguez-Puyol, Diego

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P0707UREMIC TOXINS IMPAIR SKELETAL MUSCLE REGENERATION PROCESS INDUCING CELL CYCLE ARREST AND APOPTOSIS IN CULTURED MYOBLASTS von Alcalde-Estévez, Elena, Asenjo-Bueno, Ana, Sosa, Patricia, Plaza, Patricia, Rodríguez-Puyol, Diego, Rodríguez-Puyol, Manuel, Olmos, Gemma, López-Ongil, Susana, Ruiz, Maria Piedad

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Contribución de las toxinas urémicas a la fibrosis vascular asociada a la enfermedad renal crónica von Hatem-Vaquero, Marco, de Frutos, Sergio, Luengo, Alicia, González Abajo, Alba, Griera, Mercedes, Rodríguez-Puyol, Manuel, Rodríguez-Puyol, Diego, Calleros, Laura

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HSP70 increases extracellular matrix production by human vascular smooth muscle through TGF-β1 up-regulation von González-Ramos, Marta, Calleros, Laura, López-Ongil, Susana, Raoch, Viviana, Griera, Mercedes, Rodríguez-Puyol, Manuel, de Frutos, Sergio, Rodríguez-Puyol, Diego

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FP360UREMIC TOXINS IMPAIR MYOGENIC DIFFERENTIATION PROMOTING FIBROGENESIS DIFFERENTIATION IN CULTURED MURINE MYOBLASTS von Elena, Alcalde-Estévez, Patricia, Sosa, Ana, Asenjo-Bueno, Patricia, Plaza, Diego, Rodríguez-Puyol, Manuel, Rodríguez-Puyol, Gemma, Olmos, López-Ongil, Susana, Mª Piedad, Ruíz-Torres

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FP366HYPERPHOSPHATEMIA ASSOCIATED TO CHRONIC KIDNEY DISEASE AND AGING REDUCES MYOGLOBIN EXPRESSION AND MITOCHONDRIAL ACTIVITY von Gemma, Olmos, Patricia, Sosa, Alfonso, Maria, Elena, Alcalde-Estévez, Ana, Asenjo-Bueno, Patricia, Plaza, Diego, Rodríguez-Puyol, Manuel, Rodríguez-Puyol, López-Ongil, Susana, Mª Piedad, Ruíz-Torres

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Tweak up-regulates endothelin-1 system in mouse and human endothelial cells von Martínez-Miguel, Patricia, Medrano-Andrés, Diana, Griera-Merino, Mercedes, Ortiz, Alberto, Rodríguez-Puyol, Manuel, Rodríguez-Puyol, Diego, López-Ongil, Susana

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P0980IMPLICATIONS OF ADIPOSE EARLY DOWNREGULATION OF INTEGRIN-LINKED KINASE (ILK) IN THE DEVELOPMENT OF METABOLIC SYNDROME IN MICE von Griera-Merino, Mercedes, García-Ayuso, Diego, Bohorquez Magro, Lourdes, Campillo de Blas, Sofía, Barrionuevo-González, Marta, Gutiérrez-Calabrés, Elena, Calleros, Laura, Rodríguez-Puyol, Diego, Rodríguez-Puyol, Manuel, De Frutos García, Sergio

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P0675LEUCOCYTE PODOSOME FORMATION AND ADHESION TO ENDOTHELIUM IS MEDIATED BY INTEGRIN LINKED KINASE IN CHRONIC KIDNEY DISEASE (CKD) von Campillo de Blas, Sofía, Bohorquez Magro, Lourdes, Gutiérrez-Calabrés, Elena, García Ayuso, Diego, Vaillo, David, Griera-Merino, Mercedes, De Frutos García, Sergio, Rodríguez-Puyol, Manuel, Rodríguez-Puyol, Diego, Calleros, Laura

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