Therapeutic targeting of “undruggable” MYC von Llombart, Victor, Mansour, Marc R

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Notch signaling: switching an oncogene to a tumor suppressor von Lobry, Camille, Oh, Philmo, Mansour, Marc R., Look, A. Thomas, Aifantis, Iannis

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An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element von Mansour, Marc R., Abraham, Brian J., Anders, Lars, Berezovskaya, Alla, Gutierrez, Alejandro, Durbin, Adam D., Etchin, Julia, Lawton, Lee, Sallan, Stephen E., Silverman, Lewis B., Loh, Mignon L., Hunger, Stephen P., Sanda, Takaomi, Young, Richard A., Look, A. Thomas

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ToTAL1y degraded - rapid dTAG proteolysis of TAL1 in T-cell acute lymphoblastic leukemia von Costa, Joana R, Mansour, Marc R

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Activated stromal cells transfer mitochondria to rescue acute lymphoblastic leukemia cells from oxidative stress von Burt, Richard, Dey, Aditi, Aref, Sarah, Aguiar, Melanie, Akarca, Ayse, Bailey, Katharine, Day, William, Hooper, Steven, Kirkwood, Amy, Kirschner, Kristina, Lee, Soo-Wah, Lo Celso, Cristina, Manji, Jiten, Mansour, Marc R., Marafioti, Teresa, Mitchell, Rachel J., Muirhead, Robert C., Cheuk Yan Ng, Kenton, Pospori, Constandina, Puccio, Ignazio, Zuborne-Alapi, Krisztina, Sahai, Erik, Fielding, Adele K.

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The role of noncoding mutations in blood cancers von Rahman, Sunniyat, Mansour, Marc R

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Small genomic insertions form enhancers that misregulate oncogenes von Abraham, Brian J., Hnisz, Denes, Weintraub, Abraham S., Kwiatkowski, Nicholas, Li, Charles H., Li, Zhaodong, Weichert-Leahey, Nina, Rahman, Sunniyat, Liu, Yu, Etchin, Julia, Li, Benshang, Shen, Shuhong, Lee, Tong Ihn, Zhang, Jinghui, Look, A. Thomas, Mansour, Marc R., Young, Richard A.

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A modular protein language modelling approach to immunogenicity prediction von O'Brien, Hugh, Salm, Max, Morton, Laura T, Szukszto, Maciej, O'Farrell, Felix, Boulton, Charlotte, King, Laurence, Bola, Supreet Kaur, Becker, Pablo D, Craig, Andrew, Nielsen, Morten, Samuels, Yardena, Swanton, Charles, Mansour, Marc R, Hadrup, Sine Reker, Quezada, Sergio A

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Targeting hyperactive platelet-derived growth factor receptor-β signaling in T-cell acute lymphoblastic leukemia and lymphoma von De Coninck, Stien, De Smedt, Renate, Lintermans, Beatrice, Reunes, Lindy, Kosasih, Hansen J, Reekmans, Alexandra, Brown, Lauren M, Van Roy, Nadine, Palhais, Bruno, Roels, Juliette, Van der Linden, Malaika, Van Dorpe, Jo, Ntziachristos, Panagiotis, Van Delft, Frederik W, Mansour, Marc R, Pieters, Tim, Lammens, Tim, De Moerloose, Barbara, De Bock, Charles E, Goossens, Steven, Van Vlierberghe, Pieter

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Novel activating mutations lacking cysteine in type I cytokine receptors in acute lymphoblastic leukemia von Shochat, Chen, Tal, Noa, Gryshkova, Vitalina, Birger, Yehudit, Bandapalli, Obul R., Cazzaniga, Giovanni, Gershman, Nava, Kulozik, Andreas E., Biondi, Andrea, Mansour, Marc R., Twizere, Jean-Claude, Muckenthaler, Martina U., Ben-Tal, Nir, Constantinescu, Stefan N., Bercovich, Dani, Izraeli, Shai

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Disruption of asxl1 results in myeloproliferative neoplasms in zebrafish von Gjini, Evisa, Jing, Chang-Bin, Nguyen, Ashley T, Reyon, Deepak, Gans, Emma, Kesarsing, Michiel, Peterson, Joshua, Pozdnyakova, Olga, Rodig, Scott J, Mansour, Marc R, Joung, Keith, Look, A Thomas

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Prognostic impact of the absence of biallelic deletion at the TRG locus for pediatric patients with T-cell acute lymphoblastic leukemia treated on the Medical Research Council UK A... von Farah, Nadine, Kirkwood, Amy A, Rahman, Sunniyat, Leon, Theresa, Jenkinson, Sarah, Gale, Rosemary E, Patrick, Katharine, Hancock, Jeremy, Samarasinghe, Sujith, Linch, David C, Moorman, Anthony V, Goulden, Nicholas, Vora, Ajay, Mansour, Marc R

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Prognostic Implications of NOTCH1 and FBXW7 Mutations in Adults With T-Cell Acute Lymphoblastic Leukemia Treated on the MRC UKALLXII/ECOG E2993 Protocol von MANSOUR, Marc R, SULIS, Maria L, PAIETTA, Elisabeth, ROWE, Jacob M, TALLMAN, Martin S, GOLDSTONE, Anthony H, FERRANDO, Adolfo A, LINCH, David C, DUKE, Veronique, FORONI, Letizia, JENKINSON, Sarah, KOO, Kenneth, ALLEN, Christopher G, GALE, Rosemary E, BUCK, Georgina, RICHARDS, Sue

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Current and emerging therapeutic approaches for T‐cell acute lymphoblastic leukaemia von Pocock, Rachael, Farah, Nadine, Richardson, Simon E., Mansour, Marc R.

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Synergy between loss of NF1 and overexpression of MYCN in neuroblastoma is mediated by the GAP-related domain von He, Shuning, Mansour, Marc R, Zimmerman, Mark W, Ki, Dong Hyuk, Layden, Hillary M, Akahane, Koshi, Gjini, Evisa, de Groh, Eric D, Perez-Atayde, Antonio R, Zhu, Shizhen, Epstein, Jonathan A, Look, A Thomas

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Discovery of a Secreted Tumor Suppressor Provides a Promising Therapeutic Strategy for Follicular Lymphoma von Mansour, Marc R., Look, A. Thomas

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Notch-1 Mutations Are Secondary Events in Some Patients with T-Cell Acute Lymphoblastic Leukemia von MANSOUR, Marc R, DUKE, Veronique, FORONI, Letizia, PATEL, Bella, ALLEN, Christopher G, ANCLIFF, Phil J, GALE, Rosemary E, LINCH, David C

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Anti-CCR9 chimeric antigen receptor T cells for T-cell acute lymphoblastic leukemia von Maciocia, Paul M, Wawrzyniecka, Patrycja A, Maciocia, Nicola C, Burley, Amy, Karpanasamy, Thaneswari, Devereaux, Sam, Hoekx, Malika, O'Connor, David, Leon, Theresa, Rapoz-D'Silva, Tanya, Pocock, Rachael, Rahman, Sunniyat, Gritti, Giuseppe, Yánez, Diana C, Ross, Susan, Crompton, Tessa, Williams, Owen, Lee, Lydia, Pule, Martin A, Mansour, Marc R

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Monitoring clone dynamics and reversibility in clonal haematopoiesis and myelodysplastic neoplasm associated with PARP inhibitor therapy—a role for early monitoring and interventio... von Nuttall Musson, Ellen, Miller, Rowan E., Mansour, Marc R., Lockley, Michelle, Ledermann, Jonathan A., Payne, Elspeth M.

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KPT‐330 inhibitor of CRM1 (XPO1)‐mediated nuclear export has selective anti‐leukaemic activity in preclinical models of T‐cell acute lymphoblastic leukaemia and acute myeloid leuka... von Etchin, Julia, Sanda, Takaomi, Mansour, Marc R., Kentsis, Alex, Montero, Joan, Le, Bonnie T., Christie, Amanda L., McCauley, Dilara, Rodig, Scott J., Kauffman, Michael, Shacham, Sharon, Stone, Richard, Letai, Anthony, Kung, Andrew L., Thomas Look, A.

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