IL-6/JAK/STAT3 Signaling in Breast Cancer Metastasis: Biology and Treatment von Manore, Sara G, Doheny, Daniel L, Wong, Grace L, Lo, Hui-Wen

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Hedgehog Signaling and Truncated GLI1 in Cancer von Doheny, Daniel, Manore, Sara G, Wong, Grace L, Lo, Hui-Wen

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STAT family of transcription factors in breast cancer: Pathogenesis and therapeutic opportunities and challenges von Wong, Grace L., Manore, Sara G., Doheny, Daniel L., Lo, Hui-Wen

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Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis von Doheny, Daniel, Sirkisoon, Sherona, Carpenter, Richard L., Aguayo, Noah Reeve, Regua, Angelina T., Anguelov, Marlyn, Manore, Sara G., Arrigo, Austin, Jalboush, Sara Abu, Wong, Grace L., Yu, Yang, Wagner, Calvin J., Chan, Michael, Ruiz, Jimmy, Thomas, Alexandra, Strowd, Roy, Lin, Jiayuh, Lo, Hui-Wen

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Antibody-Drug Conjugates for the Treatment of HER2-Positive Breast Cancer von Najjar, Mariana K, Manore, Sara G, Regua, Angelina T, Lo, Hui-Wen

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Breast cancer extracellular vesicles-derived miR-1290 activates astrocytes in the brain metastatic microenvironment via the FOXA2→CNTF axis to promote progression of brain metastas... von Sirkisoon, Sherona R., Wong, Grace L., Aguayo, Noah R., Doheny, Daniel L., Zhu, Dongqin, Regua, Angelina T., Arrigo, Austin, Manore, Sara G., Wagner, Calvin, Thomas, Alexandra, Singh, Ravi, Xing, Fei, Jin, Guangxu, Watabe, Kounosuke, Lo, Hui-Wen

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Correction: Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis von Doheny, Daniel, Sirkisoon, Sherona, Carpenter, Richard L., Aguayo, Noah Reeve, Regua, Angelina T., Anguelov, Marlyn, Manore, Sara G., Arrigo, Austin, Jalboush, Sara Abu, Wong, Grace L., Yu, Yang, Wagner, Calvin J., Chan, Michael, Ruiz, Jimmy, Thomas, Alexandra, Strowd, Roy, Lin, Jiayuh, Lo, Hui-Wen

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Correction: Regua et al. TrkA Interacts with and Phosphorylates STAT3 to Enhance Gene Transcription and Promote Breast Cancer Stem Cells in Triple-Negative and HER2-Enriched Breast... von Regua, Angelina T, Aguayo, Noah R, Jalboush, Sara Abu, Doheny, Daniel L, Manore, Sara G, Zhu, Dongqin, Wong, Grace L, Arrigo, Austin, Wagner, Calvin J, Yu, Yang, Thomas, Alexandra, Chan, Michael D, Ruiz, Jimmy, Jin, Guangxu, Strowd, Roy, Sun, Peiqing, Lin, Jiayuh, Lo, Hui-Wen

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Design, synthesis and analysis of novel sphingosine kinase-1 inhibitors to improve oral bioavailability von Butler, Kendarius J., Castro, Angel A., Dwyer, Tiffany S., Hardwick, Louise M., Iacino, Melody C., Manore, Sara G., Mays, Kevin M., McGlade, Caylie A., Hair, Lisa N., Parker, Erin W., Smith, Mikala R., Turnow, Morgan T., Wilson, Matthew R., Woodson, Stephanie R., Cotham, William E., Walla, Michael D., Hurlbert, Jason C., Christian Grattan, T.

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TrkA Interacts with and Phosphorylates STAT3 to Enhance Gene Transcription and Promote Breast Cancer Stem Cells in Triple-Negative and HER2-Enriched Breast Cancers von Regua, Angelina T, Aguayo, Noah R, Jalboush, Sara Abu, Doheny, Daniel L, Manore, Sara G, Zhu, Dongqin, Wong, Grace L, Arrigo, Austin, Wagner, Calvin J, Yu, Yang, Thomas, Alexandra, Chan, Michael D, Ruiz, Jimmy, Jin, Guangxu, Strowd, Roy, Sun, Peiqing, Lin, Jiayuh, Lo, Hui-Wen

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Abstract 1979: JAK2/STAT3 and TrkA pathways are frequently co-activated in triple-negative and HER2-enriched breast cancers and the co-activation correlates with an increased poten... von Regua, Angelina T., Aguayo, Noah R., Jalboush, Sara Abu, Doheny, Daniel L., Manore, Sara G., Zhu, Dongqin, Wong, Grace L., Arrigo, Austin, Wagner, Calvin J., Yu, Yang, Baylon, Karen, Thomas, Alexandra, Chan, Michael D., Ruiz, Jimmy, Jin, Guangxu, Strowd, Roy E., Sun, Peiqing, Metheny-Barlow, Linda J., Lin, Jiayuh, Lo, Hui-Wen

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Abstract 1721: Dual targeting of JAK2 and TrkA inhibits breast cancer cell stemness, enhances apoptosis, and delays tumor growth of triple-negative and HER2-enriched breast cancers von Regua, Angelina T., Najjar, Mariana K., Wong, Grace L., Manore, Sara G., Arrigo, Austin, Lo, Hui-Wen

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Abstract 1039: TrkA and JAK2-STAT3 pathway crosstalk promotes breast cancer stem cells in HER2-enriched and triple-negative breast cancers von Regua, Angelina T., Zhu, Dongqin, Doheny, Daniel L., Wong, Grace L., Manore, Sara G., Wagner, Calvin J., Arrigo, Austin, Najjar, Mariana, Lo, Hui-Wen

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Abstract 92: tGLI1 and IL-6/IL-6R/GP130/STAT3 pathways cooperate to promote breast cancer stem cells and are co-activated in HER2-enriched and triple-negative breast cancers von Manore, Sara G., Doheny, Daniel L., Zhu, Dongqin, Wong, Grace L., Regua, Angelina T., Arrigo, Austin, Wagner, Calvin J., Najjar, Mariana, Lo, Hui-Wen

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Abstract 2354: Astrocytes activated by tGLI1-expressing breast cancer brain metastases upregulate CNTF to activate astrocytes and promote breast cancer stem cells von Wong, Grace L., Sirkisoon, Sherona R., Aguayo, Noah R., Doheny, Daniel L., Zhu, Dongqin, Regua, Angelina T., Arrigo, Austin, Manore, Sara G., Wagner, Calvin J., Thomas, Alexandra, Singh, Ravi, Xing, Fei, Jin, Guangxu, Watabe, Kounosuke, Lo, Hui-Wen

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Multiple models for outbreak decision support in the face of uncertainty von Shea, Katriona, Borchering, Rebecca K, Probert, William J M, Howerton, Emily, Bogich, Tiffany L, Li, Shou-Li, van Panhuis, Willem G, Viboud, Cecile, Aguás, Ricardo, Belov, Artur A, Bhargava, Sanjana H, Cavany, Sean M, Chang, Joshua C, Chen, Cynthia, Chen, Jinghui, Chen, Shi, Chen, YangQuan, Childs, Lauren M, Chow, Carson C, Crooker, Isabel, Del Valle, Sara Y, España, Guido, Fairchild, Geoffrey, Gerkin, Richard C, Germann, Timothy C, Gu, Quanquan, Guan, Xiangyang, Guo, Lihong, Hart, Gregory R, Hladish, Thomas J, Hupert, Nathaniel, Janies, Daniel, Kerr, Cliff C, Klein, Daniel J, Klein, Eili Y, Lin, Gary, Manore, Carrie, Meyers, Lauren Ancel, Mittler, John E, Mu, Kunpeng, Núñez, Rafael C, Oidtman, Rachel J, Pasco, Remy, Pastore Y Piontti, Ana, Paul, Rajib, Pearson, Carl A B, Perdomo, Dianela R, Perkins, T Alex, Pierce, Kelly, Pillai, Alexander N, Rael, Rosalyn Cherie, Rosenfeld, Katherine, Ross, Chrysm Watson, Spencer, Julie A, Stoltzfus, Arlin B, Toh, Kok Ben, Vattikuti, Shashaank, Vespignani, Alessandro, Wang, Lingxiao, White, Lisa J, Xu, Pan, Yang, Yupeng, Yogurtcu, Osman N, Zhang, Weitong, Zhao, Yanting, Zou, Difan, Ferrari, Matthew J, Pannell, David, Tildesley, Michael J, Seifarth, Jack, Johnson, Elyse, Biggerstaff, Matthew, Johansson, Michael A, Slayton, Rachel B, Levander, John D, Stazer, Jeff, Kerr, Jessica, Runge, Michael C

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Multiple models for outbreak decision support in the face of uncertainty von Shea, Katriona, Borchering, Rebecca K, Probert, William JM, Howerton, Emily, Bogich, Tiffany L, Li, Shou-Li, van Panhuis, Willem G, Viboud, Cecile, Aguás, Ricardo, Belov, Artur A, Bhargava, Sanjana H, Cavany, Sean M, Chang, Joshua C, Chen, Cynthia, Chen, Jinghui, Chen, Shi, Chen, YangQuan, Childs, Lauren M, Chow, Carson C, Crooker, Isabel, Del Valle, Sara Y, España, Guido, Fairchild, Geoffrey, Gerkin, Richard C, Germann, Timothy C, Gu, Quanquan, Guan, Xiangyang, Guo, Lihong, Hart, Gregory R, Hladish, Thomas J, Hupert, Nathaniel, Janies, Daniel, Kerr, Cliff C, Klein, Daniel J, Klein, Eili Y, Lin, Gary, Manore, Carrie, Meyers, Lauren Ancel, Mittler, John E, Mu, Kunpeng, Núñez, Rafael C, Oidtman, Rachel J, Pasco, Remy, Pastore Y Piontti, Ana, Paul, Rajib, Pearson, Carl AB, Perdomo, Dianela R, Perkins, T Alex, Pierce, Kelly, Pillai, Alexander N, Rael, Rosalyn Cherie, Rosenfeld, Katherine, Ross, Chrysm Watson, Spencer, Julie A, Stoltzfus, Arlin B, Toh, Kok Ben, Vattikuti, Shashaank, Vespignani, Alessandro, Wang, Lingxiao, White, Lisa J, Xu, Pan, Yang, Yupeng, Yogurtcu, Osman N, Zhang, Weitong, Zhao, Yanting, Zou, Difan, Ferrari, Matthew J, Pannell, David, Tildesley, Michael J, Seifarth, Jack, Johnson, Elyse, Biggerstaff, Matthew, Johansson, Michael A, Slayton, Rachel B, Levander, John D, Stazer, Jeff, Kerr, Jessica, Runge, Michael C

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