841P IGM-2323 is a CD20xCD3 IgM bispecific T-cell engager that kills low CD20-expressing and rituximab-resistant B-cell lymphomas von Li, K., Kotturi, M.F., Manlusoc, M., Yun, R., Hinton, P.R., Logronio, K., Baliga, R., Hernandez, G., Sinclair, A.M., Carroll, S.F., Godfrey, W.R., Keyt, B.A.

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Novel CD123xCD3 Bispecific Igm Antibody, Igm-2537, Potently Induces T-Cell Mediated Cytotoxicity of Acute Myeloid Leukemia Cells In Vivo and in Vitro with Minimal Cytokine Release von Li, Gene, Ye, Zhongde, Yakkundi, Poonam, Manlusoc, Marigold, Logronio, Kathryn, Tahrani, Leyla, Rosete, Rodnie, Bernados, David, Hinton, Paul, Pandya, Deepal, Hanna, Nardeen, Anantam, Jey, Kotturi, Maya F, Bogaert, Liz, Hong, Jiyoung, Tsai, Christina, Manley, Thomas, Keyt, Bruce A, Sinclair, Angus M., Liu, Liqin

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Abstract 4179: High valency of IGM-2323, a CD20xCD3 IgM bispecific T cell engager, displaces rituximab binding and induces potent B lymphoma cell killing von Hart, Kevin C., Logronio, Kathryn, Li, Mandy, Yakkundi, Poonam, Manlusoc, Marigold, Li, Keyu, Hinton, Paul R., Ng, Dean, Leabman, Maya K., Hernandez, Genevive, Manley, Thomas, Sinclair, Angus M., Carroll, Stephen F., Keyt, Bruce A., Kotturi, Maya F.

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