Regioselective Synthesis of 1,3,5-Tri- and 1,3,4,5-Tetrasubstituted Pyrazoles from N-Arylhydrazones and Nitroolefins von Deng, Xiaohu, Mani, Neelakandha S

Volltext

Oxysterols direct B-cell migration through EBI2 von Liu, Changlu, Yang, Xia V., Wu, Jiejun, Kuei, Chester, Mani, Neelakandha S., Zhang, Li, Yu, Jingxue, Sutton, Steven W., Qin, Ning, Banie, Homayon, Karlsson, Lars, Sun, Siquan, Lovenberg, Timothy W.

Volltext

Oxysterols are agonist ligands of RORγt and drive Th17 cell differentiation von Soroosh, Pejman, Wu, Jiejun, Xue, Xiaohua, Song, Jiao, Sutton, Steven W., Sablad, Marciano, Yu, Jingxue, Nelen, Marina I., Liu, Xuejun, Castro, Glenda, Luna, Rosa, Crawford, Shelby, Banie, Homayon, Dandridge, Rose A., Deng, Xiaohu, Bittner, Anton, Kuei, Chester, Tootoonchi, Mandana, Rozenkrants, Natasha, Herman, Krystal, Gao, Jingjin, Yang, Xia V., Sachen, Kacey, Ngo, Karen, Fung-Leung, Wai-Ping, Nguyen, Steven, de Leon-Tabaldo, Aimee, Blevitt, Jonathan, Zhang, Yan, Cummings, Maxwell D., Rao, Tadimeti, Mani, Neelakandha S., Liu, Changlu, McKinnon, Murray, Milla, Marcos E., Fourie, Anne M., Sun, Siquan

Volltext

Facile Assembly of Fused Benzo[4,5]furo Heterocycles von Liu, Jing, Fitzgerald, Anne E, Mani, Neelakandha S

Volltext

Synthesis and Antitumor Activity of an Inhibitor of Fatty Acid Synthase von Kuhajda, Francis P., Pizer, Ellen S., Li, Ji Nong, Mani, Neelakandha S., Frehywot, Gojeb L., Townsend, Craig A.

Volltext

Gram-Scale Synthesis of a β‑Secretase 1 (BACE 1) Inhibitor von Allison, Brett D, Mani, Neelakandha S

Volltext

CuI-Catalyzed Amination of Arylhalides with Guanidines or Amidines: A Facile Synthesis of 1-H-2-Substituted Benzimidazoles von Deng, Xiaohu, McAllister, Heather, Mani, Neelakandha S

Volltext

Base-Mediated Reaction of Hydrazones and Nitroolefins with a Reversed Regioselectivity:  A Novel Synthesis of 1,3,4-Trisubstituted Pyrazoles von Deng, Xiaohu, Mani, Neelakandha S

Volltext

Reaction of N-Monosubstituted Hydrazones with Nitroolefins:  A Novel Regioselective Pyrazole Synthesis von Deng, Xiaohu, Mani, Neelakandha S

Volltext

Regioselective Electrophilic Fluorination of Rationally Designed Imidazole Derivatives von Albertshofer, Klaus, Mani, Neelakandha S

Volltext

Reactions between Weinreb Amides and 2-Magnesiated Oxazoles:  A Simple and Efficient Preparation of 2-Acyl Oxazoles von Pippel, Daniel J, Mapes, Christopher M, Mani, Neelakandha S

Volltext

Discovery of 6-N,N-Bis(2,2,2-trifluoroethyl)amino- 4-trifluoromethylquinolin-2(1H)-one as a Novel Selective Androgen Receptor Modulator von van Oeveren, Arjan, Motamedi, Mehrnouch, Mani, Neelakandha S, Marschke, Keith B, López, Francisco J, Schrader, William T, Negro-Vilar, Andrés, Zhi, Lin

Volltext

Synthesis of 4-Arylpiperidines from 1-Benzyl-4-piperidone:  Application of the Shapiro Reaction and Alkenylsilane Cross-Coupling von Morrill, Christie, Mani, Neelakandha S

Volltext

A Step-Economical Route to Fused 1,2,3-Triazoles via an Intramolecular 1,3-Dipolar Cycloaddition between a Nitrile and an in Situ Generated Aryldiazomethane von Mani, Neelakandha S, Fitzgerald, Anne E

Volltext

Reactivity-Controlled Regioselectivity: A Regiospecific Synthesis of 1,2-Disubstituted Benzimidazoles von Deng, Xiaohu, Mani, Neelakandha S.

Volltext

The synthesis of 2-amino-4(3H)-quinazolinones and related heterocycles via a mild electrocyclization of aryl guanidines von Sales, Zachary S., Mani, Neelakandha S., Allison, Brett D.

Volltext

A facile, environmentally benign sulfonamide synthesis in water von Deng, Xiaohu, Mani, Neelakandha S

Volltext

An Efficient Route to 4-Aryl-5-pyrimidinylimidazoles via Sequential Functionalization of 2,4-Dichloropyrimidine von Deng, Xiaohu, Mani, Neelakandha S

Volltext

Allyl-Assisted, Cu(I)-Catalyzed Azide–Alkyne Cycloaddition/Allylation Reaction: Assembly of the [1,2,3]Triazolo-4,5,6,7-tetrahydropyridine Core Structure von Deng, Xiaohu, Liang, Jimmy, Allison, Brett B, Dvorak, Curt, McAllister, Heather, Savall, Brad M, Mani, Neelakandha S

Volltext

Novel Octahydropyrrolo[3,4‑c]pyrroles Are Selective Orexin‑2 Antagonists: SAR Leading to a Clinical Candidate von Letavic, Michael A., Bonaventure, Pascal, Carruthers, Nicholas I., Dugovic, Christine, Koudriakova, Tatiana, Lord, Brian, Lovenberg, Timothy W., Ly, Kiev S., Mani, Neelakandha S., Nepomuceno, Diane, Pippel, Daniel J., Rizzolio, Michele, Shelton, Jonathan E., Shah, Chandra R., Shireman, Brock T., Young, Lana K., Yun, Sujin

Volltext