968 PD-1hiFoxp3-CD4+ tumor-infiltrating T-cell lineage commitment impacts the immunotherapy outcome von Mangarin, Levi Mark, Martis, Stephen, Orlando, Andrea, Schad, Sara, Wolchok, Jedd D, Greenbaum, Benjamin, Merghoub, Taha, Zappasodi, Roberta

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1444 Pharmacologic LDH inhibition redirects intratumoral glucose consumption and improves response to CTLA-4 blockade von Verma, Svena, Zappasodi, Roberta, Budhu, Sadna, Serganova, Inna, Dong, Lauren, Mangarin, Levi Mark, Marouf, Yacine, Khan, Jonathan F, Wolchok, Jedd D, Merghoub, Taha

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T cell immunotherapies engage neutrophils to eliminate tumor antigen escape variants von Hirschhorn, Daniel, Budhu, Sadna, Kraehenbuehl, Lukas, Gigoux, Mathieu, Schröder, David, Chow, Andrew, Ricca, Jacob M., Gasmi, Billel, De Henau, Olivier, Mangarin, Levi Mark B., Li, Yanyun, Hamadene, Linda, Flamar, Anne-Laure, Choi, Hyejin, Cortez, Czrina A., Liu, Cailian, Holland, Aliya, Schad, Sara, Schulze, Isabell, Betof Warner, Allison, Hollmann, Travis J., Arora, Arshi, Panageas, Katherine S., Rizzuto, Gabrielle A., Duhen, Rebekka, Weinberg, Andrew D., Spencer, Christine N., Ng, David, He, Xue-Yan, Albrengues, Jean, Redmond, David, Egeblad, Mikala, Wolchok, Jedd D., Merghoub, Taha

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878 T cell immunotherapies recruit and activate neutrophils to eliminate tumor antigen escape variants von Hirschhorn, Daniel, Budhu, Sadna, Kraehenbuehl, Lukas, Gigoux, Mathieu, Schröder, David, Chow, Andrew, Ricca, Jacob M, Gasmi, Billel, De Henau, Olivier, Mangarin, Levi Mark B, Li, Yanyun, Flamar, Anne-Laure, Choi, Heyjin, Cortez, Czrina A, Liu, Cailian, Holland, Aliya, Schad, Sara, Schulze, Isabell, Hamadene, Linda, Warner, Allison Betof, Hollmann, Travis, Arora, Arshi, Panageas, Katherine S, Duhen, Rebekka, Weinberg, Andrew D, Rizzuto, Gabrielle A, Spencer, Christine N, Ng, David, He, Xue-Yan, Albrengues, Jean, Redmond, David, Egeblad, Mikala, Wolchok, Jedd D, Merghoub, Taha

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A delicate interplay between adaptive and innate immunity caused by immunotherapy triggers tumor immunity and aseptic inflammation von Hirschhorn, Daniel, Ricca, Jacob, Gasmi, Billel, DeHanau, Olivier, Mangarin, Levi Mark, Budhu, Sadna, Li, Yanyn, Cortez, Czarina, Liu, Cailian, Zappasodi, Roberta, Houghton, Sean, Betof, Allison, Lacouture, Mario, Hollman, Travis, Albrengues, Jean, Egeblad, Mikala, Wolchok, Jedd D., Merghoub, Taha

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Abstract 250: Activating canonical p53 functions in tumor-associated macrophages improves immune checkpoint blockade efficacy von Ghosh, Arnab, Michel, Judith, Venkatesh, Divya, Mezzadra, Riccardo, Dong, Lauren, Samaan, Fadi, Gomez, Ricardo, Suek, Nathan, Holland, Aliya, Ho, Yu-Jui, Abu-Akeel, Mohsen, Campesato, Luis Felipe, Mangarin, Levi Mark Bala, Liu, Cailian, Zhong, Hong, Budhu, Sadna, Chow, Andrew, Zappasodi, Roberta, Ruscetti, Marcus, Lowe, Scott W., Merghoub, Taha, Wolchok, Jedd D.

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Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine von Campesato, Luis Felipe, Budhu, Sadna, Tchaicha, Jeremy, Weng, Chien-Huan, Gigoux, Mathieu, Cohen, Ivan Jose, Redmond, David, Mangarin, Levi, Pourpe, Stephane, Liu, Cailian, Zappasodi, Roberta, Zamarin, Dmitriy, Cavanaugh, Jill, Castro, Alfredo C., Manfredi, Mark G., McGovern, Karen, Merghoub, Taha, Wolchok, Jedd D.

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