Therapeutic Potential of Flavonoids in Pain and Inflammation: Mechanisms of Action, Pre-Clinical and Clinical Data, and Pharmaceutical Development von Ferraz, Camila R, Carvalho, Thacyana T, Manchope, Marília F, Artero, Nayara A, Rasquel-Oliveira, Fernanda S, Fattori, Victor, Casagrande, Rubia, Verri, Jr, Waldiceu A

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Vanillic Acid Inhibits Inflammatory Pain by Inhibiting Neutrophil Recruitment, Oxidative Stress, Cytokine Production, and NFκB Activation in Mice von Calixto-Campos, Cássia, Carvalho, Thacyana T, Hohmann, Miriam S. N, Pinho-Ribeiro, Felipe A, Fattori, Victor, Manchope, Marília F, Zarpelon, Ana C, Baracat, Marcela M, Georgetti, Sandra R, Casagrande, Rubia, Verri, Waldiceu A

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Naringenin Inhibits Superoxide Anion-Induced Inflammatory Pain: Role of Oxidative Stress, Cytokines, Nrf-2 and the NO−cGMP−PKG−KATPChannel Signaling Pathway von Manchope, Marília F., Calixto-Campos, Cássia, Coelho-Silva, Letícia, Zarpelon, Ana C., Pinho-Ribeiro, Felipe A., Georgetti, Sandra R., Baracat, Marcela M., Casagrande, Rúbia, Verri, Waldiceu A.

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Naringenin reduces inflammatory pain in mice von Pinho-Ribeiro, Felipe A., Zarpelon, Ana C., Fattori, Victor, Manchope, Marília F., Mizokami, Sandra S., Casagrande, Rubia, Verri, Waldiceu A.

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Contribution of Nrf2 Modulation to the Mechanism of Action of Analgesic and Anti-inflammatory Drugs in Pre-clinical and Clinical Stages von Staurengo-Ferrari, Larissa, Badaro-Garcia, Stephanie, Hohmann, Miriam S N, Manchope, Marília F, Zaninelli, Tiago H, Casagrande, Rubia, Verri, Jr, Waldiceu A

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Naringenin: an analgesic and anti-inflammatory citrus flavanone von Manchope, Marília F, Casagrande, Rubia, Verri, Jr, Waldiceu A

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Naringenin Inhibits Superoxide Anion-Induced Inflammatory Pain: Role of Oxidative Stress, Cytokines, Nrf-2 and the NO-cGMP-PKG-KATP Channel Signaling Pathway von Manchope, Marília F, Calixto-Campos, Cássia, Coelho-Silva, Letícia, Zarpelon, Ana C, Pinho-Ribeiro, Felipe A, Georgetti, Sandra R, Baracat, Marcela M, Casagrande, Rúbia, Verri, Jr, Waldiceu A

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Methyl gallate attenuates inflammation induced by Toll-like receptor ligands by inhibiting MAPK and NF-Κb signaling pathways von Correa, Luana Barbosa, Seito, Leonardo Noboru, Manchope, Marília F., Verri, Waldiceu A., Cunha, Thiago Mattar, Henriques, Maria G., Rosas, Elaine Cruz

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Hesperidin Methyl Chalcone Reduces the Arthritis Caused by TiO2 in Mice: Targeting Inflammation, Oxidative Stress, Cytokine Production, and Nociceptor Sensory Neuron Activation von Artero, Nayara A., Manchope, Marília F., Carvalho, Thacyana T., Saraiva-Santos, Telma, Bertozzi, Mariana M., Carneiro, Jessica A., Franciosi, Anelise, Dionisio, Amanda M., Zaninelli, Tiago H., Fattori, Victor, Ferraz, Camila R., Piva, Maiara, Mizokami, Sandra S., Camilios-Neto, Doumit, Casagrande, Rubia, Verri, Waldiceu A.

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Therapeutic activity of lipoxin A4 in TiO2-induced arthritis in mice: NF-κB and Nrf2 in synovial fluid leukocytes and neuronal TRPV1 mechanisms von Saraiva-Santos, Telma, Zaninelli, Tiago H., Manchope, Marília F., Andrade, Ketlem C., Ferraz, Camila R., Bertozzi, Mariana M., Artero, Nayara A., Franciosi, Anelise, Badaro-Garcia, Stephanie, Staurengo-Ferrari, Larissa, Borghi, Sergio M., Ceravolo, Graziela S., Andrello, Avacir Casanova, Zanoveli, Janaína Menezes, Rogers, Michael S., Casagrande, Rubia, Pinho-Ribeiro, Felipe A., Verri, Waldiceu A.

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Probucol attenuates lipopolysaccharide-induced leukocyte recruitment and inflammatory hyperalgesia: effect on NF-кB activation and cytokine production von Zucoloto, Amanda Z., Manchope, Marília F., Staurengo-Ferrari, Larissa, Pinho-Ribeiro, Felipe A., Zarpelon, Ana C., Saraiva, André L.L., Cecílio, Nerry Tatiana, Alves-Filho, José C., Cunha, Thiago M., Menezes, Gustavo B., Cunha, Fernando Q., Casagrande, Rubia, Verri, Waldiceu A.

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Jararhagin, a snake venom metalloproteinase, induces mechanical hyperalgesia in mice with the neuroinflammatory contribution of spinal cord microglia and astrocytes von Ferraz, Camila R., Carvalho, Thacyana T., Fattori, Victor, Saraiva-Santos, Telma, Pinho-Ribeiro, Felipe A., Borghi, Sergio M., Manchope, Marília F., Zaninelli, Tiago H., Cunha, Thiago M., Casagrande, Rubia, Clissa, Patricia B., Verri, Waldiceu A.

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Peripheral mechanisms involved in Tityus bahiensis venom-induced pain von Ferraz, Camila R., Manchope, Marília F., Andrade, Ketlem C., Saraiva-Santos, Telma, Franciosi, Anelise, Zaninelli, Tiago H., Bagatim-Souza, Julia, Borghi, Sergio M., Cândido, Denise M., Knysak, Irene, Casagrande, Rubia, Kwasniewski, Fábio H., Verri, Waldiceu A.

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Jararhagin-induced mechanical hyperalgesia depends on TNF-α, IL-1β and NFκB in mice von Ferraz, Camila R., Calixto-Campos, Cássia, Manchope, Marília F., Casagrande, Rubia, Clissa, Patrícia B., Baldo, Cristiani, Verri, Waldiceu A.

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Probucol Ameliorates Complete Freund’s Adjuvant-Induced Hyperalgesia by Targeting Peripheral and Spinal Cord Inflammation von Zucoloto, Amanda Z., Manchope, Marília F., Borghi, Sergio M., dos Santos, Telma S., Fattori, Victor, Badaro-Garcia, Stephanie, Camilios-Neto, Doumit, Casagrande, Rubia, Verri, Waldiceu A.

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The granulopoietic cytokine granulocyte colony-stimulating factor (G-CSF) induces pain: analgesia by rutin von Carvalho, Thacyana T., Mizokami, Sandra S., Ferraz, Camila R., Manchope, Marília F., Borghi, Sergio M., Fattori, Victor, Calixto-Campos, Cassia, Camilios-Neto, Doumit, Casagrande, Rubia, Verri, Waldiceu A.

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Naringenin mitigates titanium dioxide (TiO2)-induced chronic arthritis in mice: role of oxidative stress, cytokines, and NFκB von Manchope, Marília F., Artero, Nayara A., Fattori, Victor, Mizokami, Sandra S., Pitol, Dimitrius L., Issa, João P. M., Fukada, Sandra Y., Cunha, Thiago M., Alves-Filho, José C., Cunha, Fernando Q., Casagrande, Rubia, Verri, Waldiceu A.

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Fermented (By Monascus purpureus or Aspergillus oryzae) and Non-Fermented Defatted Soybean Flour Extracts: Biological Insight and Mechanism Differences in Inflammatory Pain and Per... von Manchope, Marília F., Bertozzi, Mariana M., Borghi, Sergio M., Handa, Cíntia L., Queiroz-Cancian, Mariana A., Ferraz, Camila R., Mizokami, Sandra S., Badaró-Garcia, Stephanie, Andrade, Ketlem C., Zaninelli, Tiago H., Spinosa, Wilma A., Georgetti, Sandra R., Ida, Elza I., Verri, Waldiceu A., Casagrande, Rubia

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Chikungunya Virus and Its Envelope Protein E2 Induce Hyperalgesia in Mice: Inhibition by Anti-E2 Monoclonal Antibodies and by Targeting TRPV1 von Segato-Vendrameto, Carina Z, Zanluca, Camila, Zucoloto, Amanda Z, Zaninelli, Tiago H, Bertozzi, Mariana M, Saraiva-Santos, Telma, Ferraz, Camila R, Staurengo-Ferrari, Larissa, Badaro-Garcia, Stephanie, Manchope, Marília F, Dionisio, Amanda M, Pinho-Ribeiro, Felipe A, Borghi, Sergio M, Mosimann, Ana Luiza Pamplona, Casagrande, Rubia, Bordignon, Juliano, Fattori, Victor, Santos, Claudia N Duarte Dos, Verri, Waldiceu A

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Probucol attenuates overt pain-like behavior and carrageenan-induced inflammatory hyperalgesia and leukocyte recruitment by inhibiting NF-кB activation and cytokine production with... von Zucoloto, Amanda Z., Manchope, Marília F., Staurengo-Ferrari, Larrisa, Alves-Filho, José C., Cunha, Thiago M., Antunes, Maísa M., Menezes, Gustavo B., Cunha, Fernando Q., Casagrande, Rubia, Verri, Waldiceu A.

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