Oxidative stress‐alleviating strategies to improve recombinant protein production in CHO cells von Chevallier, Valentine, Andersen, Mikael Rørdam, Malphettes, Laetitia

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Macroscopic modeling of mammalian cell growth and metabolism von Ben Yahia, Bassem, Malphettes, Laetitia, Heinzle, Elmar

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Application of a curated genome-scale metabolic model of CHO DG44 to an industrial fed-batch process von Calmels, Cyrielle, McCann, Andréa, Malphettes, Laetitia, Andersen, Mikael Rørdam

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Application of a genome-scale model in tandem with enzyme assays for identification of metabolic signatures of high and low CHO cell producers von Calmels, Cyrielle, Arnoult, Solène, Ben Yahia, Bassem, Malphettes, Laetitia, Andersen, Mikael Rørdam

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Predictive macroscopic modeling of cell growth, metabolism and monoclonal antibody production: Case study of a CHO fed-batch production von Ben Yahia, Bassem, Malphettes, Laetitia, Heinzle, Elmar

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Scale-up considerations for monoclonal antibody production process: an oxygen transfer flux approach von Gimenez, Laura, Simonet, Claire, Malphettes, Laetitia

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Use of novel cystine analogs to decrease oxidative stress and control product quality von Chevallier, Valentine, Zoller, Marvin, Kochanowski, Nadine, Andersen, Mikael R., Workman, Christopher T., Malphettes, Laetitia

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Characterization of glutathione proteome in CHO cells and its relationship with productivity and cholesterol synthesis von Chevallier, Valentine, Schoof, Erwin M., Malphettes, Laetitia, Andersen, Mikael R., Workman, Christopher T.

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Segmented linear modeling of CHO fed‐batch culture and its application to large scale production von Ben Yahia, Bassem, Gourevitch, Boris, Malphettes, Laetitia, Heinzle, Elmar

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Medium and feed optimization for fed-batch production of a monoclonal antibody in CHO cells von Kochanowski, Nadine, Siriez, Gaetan, Roosens, Sarah, Malphettes, Laetitia

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Development and fine-tuning of a scale down model for process characterization studies of a monoclonal antibody upstream production process von Harmsen, Mareike, Stofferis, Jimmy, Malphettes, Laetitia

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Impact of RNA interference on gene networks von Malphettes, Laetitia, Fussenegger, Martin

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Highly efficient deletion of FUT8 in CHO cell lines using zinc-finger nucleases yields cells that produce completely nonfucosylated antibodies von Malphettes, Laetitia, Freyvert, Yevgeniy, Chang, Jennifer, Liu, Pei-Qi, Chan, Edmond, Miller, Jeffrey C, Zhou, Zhe, Nguyen, Thu, Tsai, Christina, Snowden, Andrew W, Collingwood, Trevor N, Gregory, Philip D, Cost, Gregory J

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Improved transgene expression fine-tuning in mammalian cells using a novel transcription–translation network von Malphettes, Laetitia, Fussenegger, Martin

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Technology transfer and scale down model development strategy for biotherapeutics produced in mammalian cells von Kochanowski, Nadine, Malphettes, Laetitia

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Overcoming the clarification challenges of high cell density culture von Gimenez, Laura, Kawkabani, Elie E, Jacobs, Pieter, Malphettes, Laetitia

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Process development and optimization of fed-batch production processes for therapeutic proteins by CHO cells von Clincke, Marie-Françoise, Harmsen, Mareike, Malphettes, Laetitia

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Macrolide- and tetracycline-adjustable siRNA-mediated gene silencing in mammalian cells using polymerase II-dependent promoter derivatives von Malphettes, Laetitia, Fussenegger, Martin

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Macrolide- and tetracycline-adjustable siRNA-mediated gene silencing in mammalian cells usuing polymerase II-dependent promoter derivatives von Malphettes, Laetitia, Fussenegger, Martin

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ambr™ Mini-bioreactor as a high-throughput tool for culture process development to accelerate transfer to stainless steel manufacturing scale: comparability study from process perf... von Delouvroy, Frédéric, Siriez, Gaetan, Tran, An-Vy, Mukankurayija, Larissa, Kochanowski, Nadine, Malphettes, Laetitia

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