The unfolded protein response in neurodegenerative disorders – therapeutic modulation of the PERK pathway von Hughes, Daniel, Mallucci, Giovanna R.

Volltext

Review: Modulating the unfolded protein response to prevent neurodegeneration and enhance memory von Halliday, Mark, Mallucci, Giovanna R.

Volltext

Noncanonical Modulation of the eIF2 Pathway Controls an Increase in Local Translation during Neural Wiring von Cagnetta, Roberta, Wong, Hovy Ho-Wai, Frese, Christian K., Mallucci, Giovanna R., Krijgsveld, Jeroen, Holt, Christine E.

Volltext

Prions: Generation and Spread Versus Neurotoxicity von Halliday, Mark, Radford, Helois, Mallucci, Giovanna R.

Volltext

miRNAs-19b, -29b-2 and -339-5p show an early and sustained up-regulation in ischemic models of stroke von Dhiraj, Dalbir K, Chrysanthou, Elvina, Mallucci, Giovanna R, Bushell, Martin

Volltext

Control of translation elongation in health and disease von Knight, John R. P., Garland, Gavin, Poyry, Tuija, Mead, Emma, Vlahov, Nikola, Sfakianos, Aristeidis, Grosso, Stefano, De-Lima-Hedayioglu, Fabio, Mallucci, Giovanna R., von der Haar, Tobias, Smales, C. Mark, Sansom, Owen J., Willis, Anne E.

Volltext

Reply: Trazodone to change the risk of neurodegeneration: bedside to bench von Halliday, Mark, Mallucci, Giovanna R

Volltext

Single treatment with RNAi against prion protein rescues early neuronal dysfunction and prolongs survival in mice with prion disease von White, Melanie D, Farmer, Michael, Mirabile, Ilaria, Brandner, Sebastian, Collinge, John, Mallucci, Giovanna R

Volltext

Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson’s disease von Tufi, Roberta, Gandhi, Sonia, de Castro, Inês P., Lehmann, Susann, Angelova, Plamena R., Dinsdale, David, Deas, Emma, Plun-Favreau, Hélène, Nicotera, Pierluigi, Abramov, Andrey Y., Willis, Anne E., Mallucci, Giovanna R., Loh, Samantha H. Y., Martins, L. Miguel

Volltext

M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss von Bradley, Sophie J, Bourgognon, Julie-Myrtille, Sanger, Helen E, Verity, Nicholas, Mogg, Adrian J, White, David J, Butcher, Adrian J, Moreno, Julie A, Molloy, Colin, Macedo-Hatch, Timothy, Edwards, Jennifer M, Wess, Jurgen, Pawlak, Robert, Read, David J, Sexton, Patrick M, Broad, Lisa M, Steinert, Joern R, Mallucci, Giovanna R, Christopoulos, Arthur, Felder, Christian C, Tobin, Andrew B

Volltext

Evaluating data integrity in ribosome footprinting datasets through modelled polysome profiles von Hedayioglu, Fabio, Mead, Emma J, O'Connor, Patrick B F, Skiotys, Matas, Sansom, Owen J, Mallucci, Giovanna R, Willis, Anne E, Baranov, Pavel V, Smales, C Mark, von der Haar, Tobias

Volltext

ASO targeting RBM3 temperature‐controlled poison exon splicing prevents neurodegeneration in vivo von Preußner, Marco, Smith, Heather L, Hughes, Daniel, Zhang, Min, Emmerichs, Ann‐Kathrin, Scalzitti, Silvia, Peretti, Diego, Swinden, Dean, Neumann, Alexander, Haltenhof, Tom, Mallucci, Giovanna R, Heyd, Florian

Volltext

Targeting Cellular Prion Protein Reverses Early Cognitive Deficits and Neurophysiological Dysfunction in Prion-Infected Mice von Mallucci, Giovanna R., White, Melanie D., Farmer, Michael, Dickinson, Andrew, Khatun, Husna, Powell, Andrew D., Brandner, Sebastian, Jefferys, John G.R., Collinge, John

Volltext

Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability von Robinson, Susan W, Bourgognon, Julie-Myrtille, Spiers, Jereme G, Breda, Carlo, Campesan, Susanna, Butcher, Adrian, Mallucci, Giovanna R, Dinsdale, David, Morone, Nobuhiro, Mistry, Raj, Smith, Tim M, Guerra-Martin, Maria, Challiss, R A John, Giorgini, Flaviano, Steinert, Joern R

Volltext

Targeting the Unfolded Protein Response as a Disease-Modifying Pathway in Dementia von Sidhom, Emad, O'Brien, John T, Butcher, Adrian J, Smith, Heather L, Mallucci, Giovanna R, Underwood, Benjamin R

Volltext

Fine‐tuning PERK signaling for neuroprotection von Halliday, Mark, Hughes, Daniel, Mallucci, Giovanna R.

Volltext

The unfolded protein response: mechanisms and therapy of neurodegeneration von Smith, Heather L, Mallucci, Giovanna R

Volltext

PERK inhibition prevents tau-mediated neurodegeneration in a mouse model of frontotemporal dementia von Radford, Helois, Moreno, Julie A., Verity, Nicholas, Halliday, Mark, Mallucci, Giovanna R.

Volltext

Developing Therapies for Neurodegenerative Disorders: Insights from Protein Aggregation and Cellular Stress Responses von Mallucci, Giovanna R, Klenerman, David, Rubinsztein, David C

Volltext

Cooling-induced SUMOylation of EXOSC10 down-regulates ribosome biogenesis von Knight, John R P, Bastide, Amandine, Peretti, Diego, Roobol, Anne, Roobol, Jo, Mallucci, Giovanna R, Smales, C Mark, Willis, Anne E

Volltext