Abstract 1004: Impact of genetic polymorphisms on colorectal adenoma recurrence and toxicity in a COX-2 inhibitor trial (Celecoxib): Results from a pilot study von Hummler, Simone, Kraus, Sarah, Toriola, Adetunji T., Poole, Elizabeth M., Kotzmann, Jana, Makar, Karen M., Kazanov, Dina, Galazan, Lior, Naumov, Inna, Duggan, David, Arber, Nadir, Ulrich, Cornelia M.

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Su1849 Genetic Polymorphisms Can Predict the Efficacy and Toxicity of Celecoxib in Patients With Adenomatous Polyps von Kraus, Sarah, Hummler, Simone, Toriola, Adetunji T, Poole, Elizabeth M, Kotzmann, Jana, Makar, Karen M, Kazanov, Diana, Galazan, Lior, Naumov, Inna, Duggan, David, Ulrich, Cornelia M, Arber, Nadir

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Differences in DNA Methylation Signatures Reveal Multiple Pathways of Progression From Adenoma to Colorectal Cancer von Luo, Yanxin, Wong, Chao-Jen, Kaz, Andrew M, Dzieciatkowski, Slavomir, Carter, Kelly T, Morris, Shelli M, Wang, Jianping, Willis, Joseph E, Makar, Karen W, Ulrich, Cornelia M, Lutterbaugh, James D, Shrubsole, Martha J, Zheng, Wei, Markowitz, Sanford D, Grady, William M

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Targeting innate immunity for tuberculosis vaccination von Khader, Shabaana A, Divangahi, Maziar, Hanekom, Willem, Hill, Philip C, Maeurer, Markus, Makar, Karen W, Mayer-Barber, Katrin D, Mhlanga, Musa M, Nemes, Elisa, Schlesinger, Larry S, van Crevel, Reinout, Vankayalapati, Raman (Krishna), Xavier, Ramnik J, Netea, Mihai G

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Dynamics of the cytotoxic T cell response to a model of acute viral infection von DeWitt, William S, Emerson, Ryan O, Lindau, Paul, Vignali, Marissa, Snyder, Thomas M, Desmarais, Cindy, Sanders, Catherine, Utsugi, Heidi, Warren, Edus H, McElrath, Juliana, Makar, Karen W, Wald, Anna, Robins, Harlan S

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Contributions of natural and anthropogenic sources to ambient ammonia in the Athabasca Oil Sands and north-western Canada von Whaley, Cynthia H, Makar, Paul A, Shephard, Mark W, Zhang, Leiming, Zhang, Junhua, Zheng, Qiong, Akingunola, Ayodeji, Wentworth, Gregory R, Murphy, Jennifer G, Kharol, Shailesh K, Cady-Pereira, Karen E

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Genetic variation in metallothionein and metal-regulatory transcription factor 1 in relation to urinary cadmium, copper, and zinc von Adams, Scott V., Barrick, Brian, Christopher, Emily P., Shafer, Martin M., Makar, Karen W., Song, Xiaoling, Lampe, Johanna W., Vilchis, Hugo, Ulery, April, Newcomb, Polly A.

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Integrative post-genome-wide association analysis of CDKN2A and TP53 SNPs and risk of esophageal adenocarcinoma von Buas, Matthew F, Levine, David M, Makar, Karen W, Utsugi, Heidi, Onstad, Lynn, Li, Xiaohong, Galipeau, Patricia C, Shaheen, Nicholas J, Hardie, Laura J, Romero, Yvonne, Bernstein, Leslie, Gammon, Marilie D, Casson, Alan G, Bird, Nigel C, Risch, Harvey A, Ye, Weimin, Liu, Geoffrey, Corley, Douglas A, Blount, Patricia L, Fitzgerald, Rebecca C, Whiteman, David C, Wu, Anna H, Reid, Brian J, Vaughan, Thomas L

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Suitability of circulating miRNAs as potential prognostic markers in colorectal cancer von Ristau, Jonas, Staffa, Jürgen, Schrotz-King, Petra, Gigic, Biljana, Makar, Karen W, Hoffmeister, Michael, Brenner, Herrmann, Ulrich, Alexis, Schneider, Martin, Ulrich, Cornelia M, Habermann, Nina

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Satellite-derived emissions of carbon monoxide, ammonia, and nitrogen dioxide from the 2016 Horse River wildfire in the Fort McMurray area von Adams, Cristen, McLinden, Chris A, Shephard, Mark W, Dickson, Nolan, Dammers, Enrico, Chen, Jack, Makar, Paul, Cady-Pereira, Karen E, Tam, Naomi, Kharol, Shailesh K, Lamsal, Lok N, Krotkov, Nickolay A

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Institutional Trends in Opioid Prescribing and Utilization after Primary Cleft Lip and Palate Repair von Sacks, Gina N., Makar, Katelyn G., Harbaugh, Calista M., Cooper, Karen A., Vercler, Christian J., Kasten, Steven J., Buchman, Steven R., Waljee, Jennifer F.

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Characterization of the association between 8q24 and colon cancer: gene-environment exploration and meta-analysis von Hutter, Carolyn M, Slattery, Martha L, Duggan, David J, Muehling, Jill, Curtin, Karen, Hsu, Li, Beresford, Shirley A A, Rajkovic, Aleksandar, Sarto, Gloria E, Marshall, James R, Hammad, Nazik, Wallace, Robert, Makar, Karen W, Prentice, Ross L, Caan, Bette J, Potter, John D, Peters, Ulrike

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Genomic Aberrations Occurring in Subsets of Serrated Colorectal Lesions but not Conventional Adenomas von BURNETT-HARTMAN, Andrea N, NEWCOMB, Polly A, POTTER, John D, PASSARELLI, Michael N, PHIPPS, Amanda I, WURSCHER, Michelle A, GRADY, William M, ZHU, Lee-Ching, UPTON, Melissa P, MAKAR, Karen W

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A Critical Role for Dnmt1 and DNA Methylation in T Cell Development, Function, and Survival von Lee, Peggy P., Fitzpatrick, David R., Beard, Caroline, Jessup, Heidi K., Lehar, Sophie, Makar, Karen W., Pérez-Melgosa, Mercedes, Sweetser, Marianne T., Schlissel, Mark S., Nguyen, Suzanne, Cherry, Sara R., Tsai, Jeff H., Tucker, Sean M., Weaver, William M., Kelso, Anne, Jaenisch, Rudolf, Wilson, Christopher B.

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MethyLight droplet digital PCR for detection and absolute quantification of infrequently methylated alleles von Yu, Ming, Carter, Kelly T, Makar, Karen W, Vickers, Kathy, Ulrich, Cornelia M, Schoen, Robert E, Brenner, Dean, Markowitz, Sanford D, Grady, William M

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Active recruitment of DNA methyltransferases regulates interleukin 4 in thymocytes and T cells von Makar, Karen W, Pérez-Melgosa, Mercedes, Wilson, Christopher B, Shnyreva, Maria, Fitzpatrick, David R, Weaver, William M

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Vitamin D Related Genes, CYP24A1 and CYP27B1, and Colon Cancer Risk von DONG, Linda M, ULRICH, Cornelia M, CAAN, Bette J, POTTER, John D, PETERS, Ulrike, HSU, Li, DUGGAN, David J, BENITEZ, Debbie S, WHITE, Emily, SLATTERY, Martha L, FARIN, Fred M, MAKAR, Karen W, CARLSON, Christopher S

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DNA methylation and the expanding epigenetics of T cell lineage commitment von Wilson, Christopher B., Makar, Karen W., Shnyreva, Maria, Fitzpatrick, David R.

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Prediagnostic Physical Activity and Colorectal Cancer Survival: Overall and Stratified by Tumor Characteristics von Hardikar, Sheetal, Newcomb, Polly A, Campbell, Peter T, Win, Aung Ko, Lindor, Noralane M, Buchanan, Daniel D, Makar, Karen W, Jenkins, Mark A, Potter, John D, Phipps, Amanda I

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Folate‐mediated one‐carbon metabolism genes and interactions with nutritional factors on colorectal cancer risk: Women's Health Initiative Observational Study von Cheng, Ting‐Yuan David, Makar, Karen W., Neuhouser, Marian L., Miller, Joshua W., Song, Xiaoling, Brown, Elissa C., Beresford, Shirley A. A., Zheng, Yingye, Poole, Elizabeth M., Galbraith, Rachel L., Duggan, David J., Habermann, Nina, Bailey, Lynn B., Maneval, David R., Caudill, Marie A., Toriola, Adetunji T., Green, Ralph, Ulrich, Cornelia M.

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