COMPARATIVE ACCURACY OF ALTERNATIVE EARLY MEASURES OF RESIDUAL DISEASE AFTER CAR19 THERAPY OF RELAPSED/REFRACTORY LBCL von Sworder, B. J., Alig, S. K., Shukla, N., Garofalo, A., Macaulay, C. W., Esfahani, M. Shahrokh, Olsen, M. N., Hamilton, J., Hosoya, H., Hamilton, M. P., Spiegel, J. Y., Baird, J. H., Carleton, M., Younes, S. F., Schroers‐Martin, J. G., Liu, C. L., Natkunam, Y., Majzner, R. G., Mackall, C. L., Miklos, D. B., Diehn, M., Frank, M. J., Kurtz, D. M., Alizadeh, A. A.

Volltext

CAR T Cells Engineered to Target Low-Density Antigens Show Efficacy and Safety

Volltext

Content-aware frame interpolation (CAFI): deep learning-based temporal super-resolution for fast bioimaging von Priessner, M, Gaboriau, DCA, Sheridan, A, Lenn, T, Garzon-Coral, C, Dunn, AR, Chubb, JR, Tousley, AM, Majzner, RG, Manor, U, Vilar, R, Laine, RF

Volltext bestellen

Novel NanoLuc substrates enable bright two-population bioluminescence imaging in animals von Su, Yichi, Walker, Joel R., Park, Yunhee, Smith, Thomas P., Liu, Lan Xiang, Hall, Mary P., Labanieh, Louai, Hurst, Robin, Wang, David C., Encell, Lance P., Kim, Namdoo, Zhang, Feijie, Kay, Mark A., Casey, Kerriann M., Majzner, Robbie G., Cochran, Jennifer R., Mackall, Crystal L., Kirkland, Thomas A., Lin, Michael Z.

Volltext

Overcoming on-target, off-tumour toxicity of CAR T cell therapy for solid tumours von Flugel, Christian L., Majzner, Robbie G., Krenciute, Giedre, Dotti, Gianpietro, Riddell, Stanley R., Wagner, Dimitrios L., Abou-el-Enein, Mohamed

Volltext

Assessment of programmed death‐ligand 1 expression and tumor‐associated immune cells in pediatric cancer tissues von Majzner, Robbie G., Simon, Jason S., Grosso, Joseph F., Martinez, Daniel, Pawel, Bruce R., Santi, Mariarita, Merchant, Melinda S., Geoerger, Birgit, Hezam, Imene, Marty, Virginie, Vielh, Phillippe, Daugaard, Mads, Sorensen, Poul H., Mackall, Crystal L., Maris, John M.

Volltext

Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling von Weber, Evan W, Parker, Kevin R, Sotillo, Elena, Lynn, Rachel C, Anbunathan, Hima, Lattin, John, Good, Zinaida, Belk, Julia A, Daniel, Bence, Klysz, Dorota, Malipatlolla, Meena, Xu, Peng, Bashti, Malek, Heitzeneder, Sabine, Labanieh, Louai, Vandris, Panayiotis, Majzner, Robbie G, Qi, Yanyan, Sandor, Katalin, Chen, Ling-Chun, Prabhu, Snehit, Gentles, Andrew J, Wandless, Thomas J, Satpathy, Ansuman T, Chang, Howard Y, Mackall, Crystal L

Volltext

Enhanced safety and efficacy of protease-regulated CAR-T cell receptors von Labanieh, Louai, Majzner, Robbie G., Klysz, Dorota, Sotillo, Elena, Fisher, Chris J., Vilches-Moure, José G., Pacheco, Kaithlen Zen B., Malipatlolla, Meena, Xu, Peng, Hui, Jessica H., Murty, Tara, Theruvath, Johanna, Mehta, Nishant, Yamada-Hunter, Sean A., Weber, Evan W., Heitzeneder, Sabine, Parker, Kevin R., Satpathy, Ansuman T., Chang, Howard Y., Lin, Michael Z., Cochran, Jennifer R., Mackall, Crystal L.

Volltext

CAR T cells with dual targeting of CD19 and CD22 in adult patients with recurrent or refractory B cell malignancies: a phase 1 trial von Spiegel, Jay Y., Patel, Shabnum, Muffly, Lori, Hossain, Nasheed M., Oak, Jean, Baird, John H., Frank, Matthew J., Shiraz, Parveen, Sahaf, Bita, Craig, Juliana, Iglesias, Maria, Younes, Sheren, Natkunam, Yasodha, Ozawa, Michael G., Yang, Eric, Tamaresis, John, Chinnasamy, Harshini, Ehlinger, Zach, Reynolds, Warren, Lynn, Rachel, Rotiroti, Maria Caterina, Gkitsas, Nikolaos, Arai, Sally, Johnston, Laura, Lowsky, Robert, Majzner, Robbie G., Meyer, Everett, Negrin, Robert S., Rezvani, Andrew R., Sidana, Surbhi, Shizuru, Judith, Weng, Wen-Kai, Mullins, Chelsea, Jacob, Allison, Kirsch, Ilan, Bazzano, Magali, Zhou, Jing, Mackay, Sean, Bornheimer, Scott J., Schultz, Liora, Ramakrishna, Sneha, Davis, Kara L., Kong, Katherine A., Shah, Nirali N., Qin, Haiying, Fry, Terry, Feldman, Steven, Mackall, Crystal L., Miklos, David B.

Volltext

Co-opting signalling molecules enables logic-gated control of CAR T cells von Tousley, Aidan M., Rotiroti, Maria Caterina, Labanieh, Louai, Rysavy, Lea Wenting, Kim, Won-Ju, Lareau, Caleb, Sotillo, Elena, Weber, Evan W., Rietberg, Skyler P., Dalton, Guillermo Nicolas, Yin, Yajie, Klysz, Dorota, Xu, Peng, de la Serna, Eva L., Dunn, Alexander R., Satpathy, Ansuman T., Mackall, Crystal L., Majzner, Robbie G.

Volltext

Tuning the Antigen Density Requirement for CAR T-cell Activity von Majzner, Robbie G, Rietberg, Skyler P, Sotillo, Elena, Dong, Rui, Vachharajani, Vipul T, Labanieh, Louai, Myklebust, June H, Kadapakkam, Meena, Weber, Evan W, Tousley, Aidan M, Richards, Rebecca M, Heitzeneder, Sabine, Nguyen, Sang M, Wiebking, Volker, Theruvath, Johanna, Lynn, Rachel C, Xu, Peng, Dunn, Alexander R, Vale, Ronald D, Mackall, Crystal L

Volltext

GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity von Heitzeneder, Sabine, Bosse, Kristopher R., Zhu, Zhongyu, Zhelev, Doncho, Majzner, Robbie G., Radosevich, Molly T., Dhingra, Shaurya, Sotillo, Elena, Buongervino, Samantha, Pascual-Pasto, Guillem, Garrigan, Emily, Xu, Peng, Huang, Jing, Salzer, Benjamin, Delaidelli, Alberto, Raman, Swetha, Cui, Hong, Martinez, Benjamin, Bornheimer, Scott J., Sahaf, Bita, Alag, Anya, Fetahu, Irfete S., Hasselblatt, Martin, Parker, Kevin R., Anbunathan, Hima, Hwang, Jennifer, Huang, Min, Sakamoto, Kathleen, Lacayo, Norman J., Klysz, Dorota D., Theruvath, Johanna, Vilches-Moure, José G., Satpathy, Ansuman T., Chang, Howard Y., Lehner, Manfred, Taschner-Mandl, Sabine, Julien, Jean-Phillipe, Sorensen, Poul H., Dimitrov, Dimiter S., Maris, John M., Mackall, Crystal L.

Volltext

Immune receptor inhibition through enforced phosphatase recruitment von Fernandes, Ricardo A., Su, Leon, Nishiga, Yoko, Ren, Junming, Bhuiyan, Aladdin M., Cheng, Ning, Kuo, Calvin J., Picton, Lora K., Ohtsuki, Shozo, Majzner, Robbie G., Rietberg, Skyler P., Mackall, Crystal L., Yin, Qian, Ali, Lestat R., Yang, Xinbo, Savvides, Christina S., Sage, Julien, Dougan, Michael, Garcia, K. Christopher

Volltext

Tumor inflammation-associated neurotoxicity von Mahdi, Jasia, Dietrich, Jorg, Straathof, Karin, Roddie, Claire, Scott, Brian J., Davidson, Tom Belle, Prolo, Laura M., Batchelor, Tracy T., Campen, Cynthia J., Davis, Kara L., Gust, Juliane, Lim, Michael, Majzner, Robbie G., Park, Julie R., Partap, Sonia, Ramakrishna, Sneha, Richards, Rebecca, Schultz, Liora, Vitanza, Nicholas A., Wang, Leo D., Mackall, Crystal L., Monje, Michelle

Volltext

Content-aware frame interpolation (CAFI): deep learning-based temporal super-resolution for fast bioimaging von Priessner, Martin, Gaboriau, David C. A., Sheridan, Arlo, Lenn, Tchern, Garzon-Coral, Carlos, Dunn, Alexander R., Chubb, Jonathan R., Tousley, Aidan M., Majzner, Robbie G., Manor, Uri, Vilar, Ramon, Laine, Romain F.

Volltext

PET Reporter Gene Imaging and Ganciclovir-Mediated Ablation of Chimeric Antigen Receptor T Cells in Solid Tumors von Murty, Surya, Labanieh, Louai, Murty, Tara, Gowrishankar, Gayatri, Haywood, Tom, Alam, Israt S, Beinat, Corinne, Robinson, Elise, Aalipour, Amin, Klysz, Dorota D, Cochran, Jennifer R, Majzner, Robbie G, Mackall, Crystal L, Gambhir, Sanjiv S

Volltext

Engineered CD47 protects T cells for enhanced antitumour immunity von Yamada-Hunter, Sean A., Theruvath, Johanna, McIntosh, Brianna J., Freitas, Katherine A., Lin, Frank, Radosevich, Molly T., Leruste, Amaury, Dhingra, Shaurya, Martinez-Velez, Naiara, Xu, Peng, Huang, Jing, Delaidelli, Alberto, Desai, Moksha H., Good, Zinaida, Polak, Roel, May, Audre, Labanieh, Louai, Bjelajac, Jeremy, Murty, Tara, Ehlinger, Zach, Mount, Christopher W., Chen, Yiyun, Heitzeneder, Sabine, Marjon, Kristopher D., Banuelos, Allison, Khan, Omair, Wasserman, Savannah L., Spiegel, Jay Y., Fernandez-Pol, Sebastian, Kuo, Calvin J., Sorensen, Poul H., Monje, Michelle, Majzner, Robbie G., Weissman, Irving L., Sahaf, Bita, Sotillo, Elena, Cochran, Jennifer R., Mackall, Crystal L.

Volltext

Latent human herpesvirus 6 is reactivated in CAR T cells von Lareau, Caleb A., Yin, Yajie, Maurer, Katie, Sandor, Katalin D., Daniel, Bence, Yagnik, Garima, Peña, José, Crawford, Jeremy Chase, Spanjaart, Anne M., Gutierrez, Jacob C., Haradhvala, Nicholas J., Riberdy, Janice M., Abay, Tsion, Stickels, Robert R., Verboon, Jeffrey M., Liu, Vincent, Buquicchio, Frank A., Wang, Fangyi, Southard, Jackson, Song, Ren, Li, Wenjing, Shrestha, Aastha, Parida, Laxmi, Getz, Gad, Maus, Marcela V., Li, Shuqiang, Moore, Alison, Roberts, Zachary J., Ludwig, Leif S., Talleur, Aimee C., Thomas, Paul G., Dehghani, Houman, Pertel, Thomas, Kundaje, Anshul, Gottschalk, Stephen, Roth, Theodore L., Kersten, Marie J., Wu, Catherine J., Majzner, Robbie G., Satpathy, Ansuman T.

Volltext

Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication von Theruvath, Johanna, Menard, Marie, Smith, Benjamin A. H., Linde, Miles H., Coles, Garry L., Dalton, Guillermo Nicolas, Wu, Wei, Kiru, Louise, Delaidelli, Alberto, Sotillo, Elena, Silberstein, John L., Geraghty, Anna C., Banuelos, Allison, Radosevich, Molly Thomas, Dhingra, Shaurya, Heitzeneder, Sabine, Tousley, Aidan, Lattin, John, Xu, Peng, Huang, Jing, Nasholm, Nicole, He, Andy, Kuo, Tracy C., Sangalang, Emma R. B., Pons, Jaume, Barkal, Amira, Brewer, Rachel E., Marjon, Kristopher D., Vilches-Moure, Jose G., Marshall, Payton L., Fernandes, Ricardo, Monje, Michelle, Cochran, Jennifer R., Sorensen, Poul H., Daldrup-Link, Heike E., Weissman, Irving L., Sage, Julien, Majeti, Ravindra, Bertozzi, Carolyn R., Weiss, William A., Mackall, Crystal L., Majzner, Robbie G.

Volltext

NOT-Gated CD93 CAR T Cells Effectively Target AML with Minimized Endothelial Cross-Reactivity von Richards, Rebecca M, Zhao, Feifei, Freitas, Katherine A, Parker, Kevin R, Xu, Peng, Fan, Amy, Sotillo, Elena, Daugaard, Mads, Oo, Htoo Zarni, Liu, Jie, Hong, Wan-Jen, Sorensen, Poul H, Chang, Howard Y, Satpathy, Ansuman T, Majzner, Robbie G, Majeti, Ravindra, Mackall, Crystal L

Volltext