Hepatitis C Virus Genetic Variability and the Presence of NS5B Resistance-Associated Mutations as Natural Polymorphisms in Selected Genotypes Could Affect the Response to NS5B Inhi... von DI MAIO, V. C, CENTO, V, MIRABELLI, C, ARTESE, A, COSTA, G, ALCARO, S, PERNO, C. F, CECCHERINI-SILBERSTEIN, F

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Successful ongoing retreatment with glecaprevir/pibrentasvir + sofosbuvir + ribavirin in a patient with HCV genotype 3 who failed glecaprevir/pibrentasvir with both NS3 and NS5A re... von Aragri, M., Milana, M., Di Maio, V.C., Lenci, I., Carioti, L., Perno, C.F., Svicher, V., Angelico, M., Ceccherini-Silberstein, F.

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More Frequent Hurricane Passage Across the Bahamian Archipelago During the Little Ice Age von Winkler, T. S., Hengstum, P. J., Donnelly, J. P., Wallace, E. J., Albury, N. A., D’Entremont, N., Hawkes, A. D., Maio, C. V., Roberts, J., Sullivan, R. M., Woodruff, J. D.

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430 KEY GENETIC SIGNATURES IN THE WHOLE pre-S1/Pre-S2/S GENE CORRELATE WITH HBV-INDUCED CARCINOGENESIS BY AFFECTING HBsAg SECRETION AND RELEASE von Svicher, V, Neumann-Fraune, M, Mirabelli, C, Salpini, R, Cento, V, Di Maio, V.-C, Bertoli, A, Alteri, C, Aragri, M, Gori, C, Micheli, V, Gubertini, G, Trimoulet, P, Fleury, H, Vecchiet, J, Iapadre, N, Barlattani, A, Mari, T, Pasquazzi, C, Sarrecchia, C, Ceccherini-Silberstein, F, Andreoni, M, Angelico, M, Verheyen, J, Perno, C.-F

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Multiclass HCV resistance to direct‐acting antiviral failure in real‐life patients advocates for tailored second‐line therapies von Di Maio, Velia C., Cento, Valeria, Aragri, Marianna, Rossi, Piera, Verucchi, Gabriella, Magni, Carlo F., Teti, Elisabetta, Micheli, Valeria, Calvaruso, Vincenza, Gianserra, Laura, Romagnoli, Dante, Cozzolongo, Raffaele, Grieco, Antonio, Morisco, Filomena, Brancaccio, Giuseppina, Di Biagio, Antonio, Loggi, Elisabetta, Mastroianni, Claudio M., Pace Palitti, Valeria, Tarquini, Pierluigi, Puoti, Massimo, Vullo, Vincenzo, Paoloni, Maurizio, Pasquazzi, Caterina, Rizzardini, Giuliano, Parruti, Giustino, Craxì, Antonio, Babudieri, Sergio, Angelico, Mario, Ceccherini‐Silberstein, Francesca, Grimaldi, A., Verucchi, G., Menzaghi, B., Quirino, T., Torti, C., Vecchiet, J., Bruzzone, B., De Maria, A., Marenco, S., Viscoli, C., Lichtner, M., Aghemo, A., Boccaccio, V., Bruno, S., Cerrone, M., Colombo, M., Danieli, E., Donato, F., Gubertini, G., Lleo, A., Magni, C.F., Mancon, A., Monico, S., Gnocchi, M., Orro, A., Milanesi, L., Bertolotti, M., Borghi, V., Mussini, C., Gaeta, G.B., Sangiovanni, V., Di Marco, V., Mazzola, A., D'Amico, E., Cacciatore, P., Consorte, A., Pieri, A., Sozio, F., Baiocchi, L., Barbaliscia, S., Biliotti, E., Carioti, L., Cerasari, G., Cerva, C., Ciotti, M., D'Ettorre, G., De Leonardis, F., De Sanctis, A., Di Maio, V.C., Furlan, C., Gallo, P., Giannelli, V., Lattanzi, B., Lenci, I., Lula, R., Malagnino, V., Manuelli, M., Milana, M., Moretti, A., Palazzo, D., Pellicelli, A., Romano, M., Sarrecchia, C., Sorbo, M.C., Spaziante, M., Mangia, A., Maida, I., Mura, M.S., Falconi, L., Di Giammartino, D.

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Optimal efficacy of interferon-free HCV retreatment after protease inhibitor failure in real life von Cento, V., Barbaliscia, S., Lenci, I., Ruggiero, T., Magni, C.F., Paolucci, S., Babudieri, S., Siciliano, M., Pasquazzi, C., Ciancio, A., Perno, C.F., Ceccherini-Silberstein, F., Micheli, V., Troshina, Y., Biliotti, E., Milana, M., Melis, M., Teti, E., Lambiase, L., Menzaghi, B., Nicolini, L.A., Marenco, S., Di Maio, V.C., Aragri, M., Pecchioli, A., Bertoli, A., Sarrecchia, C., Macera, M., Coppola, N., Puoti, M., Romagnoli, D., Pellicelli, A., Bonora, S., Novati, S., Baldanti, F., Ghisetti, V., Andreoni, M., Taliani, G., Rizzardini, G., Angelico, M.

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HCV NS3 sequencing as a reliable and clinically useful tool for the assessment of genotype and resistance mutations for clinical samples with different HCV-RNA levels von Di Maio, V C, Cento, V, Di Paolo, D, Aragri, M, De Leonardis, F, Tontodonati, M, Micheli, V, Bellocchi, M C, Antonucci, F P, Bertoli, A, Lenci, I, Milana, M, Gianserra, L, Melis, M, Di Biagio, A, Sarrecchia, C, Sarmati, L, Landonio, S, Francioso, S, Lambiase, L, Nicolini, L A, Marenco, S, Nosotti, L, Giannelli, V, Siciliano, M, Romagnoli, D, Pellicelli, A, Vecchiet, J, Magni, C F, Babudieri, S, Mura, M S, Taliani, G, Mastroianni, C, Vespasiani-Gentilucci, U, Romano, M, Morisco, F, Gasbarrini, A, Vullo, V, Bruno, S, Baiguera, C, Pasquazzi, C, Tisone, G, Picciotto, A, Andreoni, M, Parruti, G, Rizzardini, G, Angelico, M, Perno, C F, Ceccherini-Silberstein, F

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Clinical usefulness of HCV sequencing on clinical samples with different HCV-RNA levels von Ceccherini-Silberstein, F, Di Maio, V C, Cento, V, Di Paolo, D, Aragri, M, De Leonardis, F, Tontodonati, M, Micheli, V, Antonucci, F P, Campoli, R

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487 KEY PATTERNS OF HBX AND PRE-S1/S2 MUTATIONS ARE INVOLVED IN MECHANISMS UNDERLYING HBV-INDUCED HEPATOCELLULAR CARCINOMA IN VIVO von Svicher, V, Mirabelli, C, Cento, V, Salpini, R, Maio, V.-C. Di, Bertoli, A, Alteri, C, Pollicita, M, Gori, C, Micheli, V, Salso, A, Gubertini, G, Trimoulet, P, Fleury, H, Vecchiet, J, Iapadre, N, Barlattani, A, Mari, T, Pasquazzi, C, Sarrechia, C, Ceccherini-Silberstein, F, Andreoni, M, Angelico, M, Perno, C.-F

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Consequences of inaccurate hepatitis C virus genotyping on the costs of prescription of direct antiviral agents in an Italian district von Polilli, Ennio, Cento, Valeria, Restelli, Umberto, Ceccherini-Silberstein, Francesca, Aragri, Marianna, Di Maio, Velia Chiara, Sciacca, Antonina, Santoleri, Fiorenzo, Fazii, Paolo, Costantini, Alberto, Perno, Carlo Federico, Parruti, Giustino

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Improvement of ALT decay kinetics by all-oral HCV treatment: Role of NS5A inhibitors and differences with IFN-based regimens von Cento, V, Nguyen, THT, Di Carlo, D, Biliotti, E, Gianserra, L, Lenci, I, Di Paolo, D, Calvaruso, V, Teti, E, Cerrone, M, Romagnoli, D, Melis, M, Danieli, E, Menzaghi, B, Polilli, E, Siciliano, M, Nicolini, LA, Di Biagio, A, Magni, CF, Bolis, M, Antonucci, FP, Di Maio, VC, Alfieri, R, Sarmati, L, Casalino, P, Bernardini, S, Micheli, V, Rizzardini, G, Parruti, G, Quirino, T, Puoti, M, Babudieri, S, D'Arminio Monforte, A, Andreoni, M, Craxì, A, Angelico, M, Pasquazzi, C, Taliani, G, Guedj, J, Perno, CF, Ceccherini-Silberstein, F

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Key genetic markers in the full-length HBsAg gene correlate with HBV-driven carcinogenesis by affecting HBsAg secretion and release von Svicher, V, Neumann-Fraune, M, Mirabelli, C, Salpini, R, Cento, V, Di Maio, V C, Bertoli, A, Alteri, C, Aragri, M, Gori, C, Micheli, V, Salso, A, Gubertini, G, Trimoulet, P, Fleury, H, Vecchiet, J, Iapadre, N, Barlattani, A, Mari, T, Pasquazzi, C, Sarrecchia, C, Ceccherini-Silberstein, F, Andreoni, M, Angelico, M, Verhejen, J, Perno, C F

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Early detection of NS3-resistance in HCV patients with advanced disease treated with BOC/TVR-based therapy: analysis by population- and ultra-deep sequencing von Cento, V, Di Maio, V C, Di Paolo, D, Armenia, D, Micheli, V, Tontodonati, M, Antonucci, P F, Bellocchi, M C, Carioti, L, tuna, S, Bertoli, A, De Luca, F, De Leonardis, F, Madeddu, G, Navarra, P, Magni, C, Sarrecchia, C, Babudieri, S, Siciliano, M, Parruti, G, Angelico, M, Rizzardini, G, Perno, C F, Ceccherini-Silberstein, F

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Successful ongoing retreatment with glecaprevir/pibrentasvir + sofosbuvir + ribavirin in a patient with HCV genotype 3 who failed glecaprevir/pibrentasvir with both NS3 and NS5A re... von Aragri, M, Milana, M, Di Maio, V C, Lenci, I, Carioti, L, Perno, C F, Svicher, V, Angelico, M, Ceccherini-Silberstein, F

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Correlation between the reflux finding score and the reflux symptom index in patients with laryngopharyngeal reflux von Gelardi, M, Silvestri, M, Ciprandi, G

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Relieving laryngopharingeral reflux (RELIEF) survey in otolaryngology - the viewpoint of the otorhinolaryngologist von Gelardi, M, Silvestri, M, Ciprandi, G

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Relieving laryngopharingeral reflux (RELIEF) survey in otolaryngology - II the viewpoint of the patient von Gelardi, M, Silvestri, M, Ciprandi, G

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The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates Splicing von De Maio, Federico A, Risso, Guillermo, Iglesias, Nestor G, Shah, Priya, Pozzi, Berta, Gebhard, Leopoldo G, Mammi, Pablo, Mancini, Estefania, Yanovsky, Marcelo J, Andino, Raul, Krogan, Nevan, Srebrow, Anabella, Gamarnik, Andrea V

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Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma von Larkin, James, Chiarion-Sileni, Vanna, Gonzalez, Rene, Grob, Jean Jacques, Cowey, C. Lance, Lao, Christopher D, Schadendorf, Dirk, Dummer, Reinhard, Smylie, Michael, Rutkowski, Piotr, Ferrucci, Pier F, Hill, Andrew, Wagstaff, John, Carlino, Matteo S, Haanen, John B, Maio, Michele, Marquez-Rodas, Ivan, McArthur, Grant A, Ascierto, Paolo A, Long, Georgina V, Callahan, Margaret K, Postow, Michael A, Grossmann, Kenneth, Sznol, Mario, Dreno, Brigitte, Bastholt, Lars, Yang, Arvin, Rollin, Linda M, Horak, Christine, Hodi, F. Stephen, Wolchok, Jedd D

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Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma von Wolchok, Jedd D, Chiarion-Sileni, Vanna, Gonzalez, Rene, Rutkowski, Piotr, Grob, Jean-Jacques, Cowey, C. Lance, Lao, Christopher D, Wagstaff, John, Schadendorf, Dirk, Ferrucci, Pier F, Smylie, Michael, Dummer, Reinhard, Hill, Andrew, Hogg, David, Haanen, John, Carlino, Matteo S, Bechter, Oliver, Maio, Michele, Marquez-Rodas, Ivan, Guidoboni, Massimo, McArthur, Grant, Lebbé, Celeste, Ascierto, Paolo A, Long, Georgina V, Cebon, Jonathan, Sosman, Jeffrey, Postow, Michael A, Callahan, Margaret K, Walker, Dana, Rollin, Linda, Bhore, Rafia, Hodi, F. Stephen, Larkin, James

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