Preclinical Testing of CAR T Cells in a Patient-Derived Xenograft Model of Glioblastoma von Tatari, Nazanin, Maich, William T., Salim, Sabra K., Mckenna, Dillon, Venugopal, Chitra, Singh, Sheila

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Cancer-selective metabolic vulnerabilities in MYC-amplified medulloblastoma von Gwynne, William D., Suk, Yujin, Custers, Stefan, Mikolajewicz, Nicholas, Chan, Jeremy K., Zador, Zsolt, Chafe, Shawn C., Zhai, Kui, Escudero, Laura, Zhang, Cunjie, Zaslaver, Olga, Chokshi, Chirayu, Shaikh, Muhammad Vaseem, Bakhshinyan, David, Burns, Ian, Chaudhry, Iqra, Nachmani, Omri, Mobilio, Daniel, Maich, William T., Mero, Patricia, Brown, Kevin R., Quaile, Andrew T., Venugopal, Chitra, Moffat, Jason, Montenegro-Burke, J. Rafael, Singh, Sheila K.

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EXTH-51. ENHANCING GLIOBLASTOMA TREATMENT: ALLOGENEIC CAR-T CELLS OVERCOMES FUNCTIONAL DEFICITS OF PATIENT-DERIVED AUTOLOGOUS PRODUCTS von Vaseem Shaikh, Muhammad, Salim, Sabra K, Maich, William T, Ananad, Alisha, Wei, Jeffrey, Subapanditha, Minomi K, Suk, Yujin, Singh, Manoj, Tabunshchyk, Zoya, Chen, Katie, Vora, Parvez, Venugopal, Chitra, Moffat, Jason, Singh, Sheila K

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SYST-33 GENERATION OF ALLOGENEIC CAR-T CIRCUMVENTS FUNCTIONAL DEFICITS IN PATIENT-DERIVED AUTOLOGOUS PRODUCT FOR GLIOBLASTOMA von Shaikh, Muhammad Vaseem, Salim, Sabra K, Maich, William T, Anand, Alisha, Wei, Jeffrey, Subapanditha, Minomi K, Suk, Yujin, Singh, Manoj, Tabunshchyk, Zoya, Chen, Katie, Vora, Parvez, Venugopal, Chitra, Moffat, Jason, Singh, Sheila K

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AUTOLOGOUS PATIENT-DERIVED CAR-TS SHOW FUNCTIONAL DEFICITS AGAINST HUMAN GLIOBLASTOMA von Salim, Sabra K, Shaikh, Vaseem, Maich, William T, Anand, Alisha, Brakel, Benjamin, Wei, Jeffrey, Subapanditha, Minomi K, Alizada, Zahra, Suk, Yujin, Singh, Manoj, Dimitrov, Vassil, Tabunshchyk, Zoya, Chen, Katie, Vora, Parvez, Venugopal, Chitra, Moffat, Jason, Singh, Sheila K

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Abstract 6028: Cancer-selective metabolic vulnerabilities in MYC-amplified medulloblastoma von Gwynne, William D., Suk, Yujin Suk, Custers, Stefan, Mikolajewicz, Nicholas, Chan, Jeremy K., Zador, Zsolt, Chafe, Shawn C., Zhai, Kui, Escudero, Laura, Zhang, Cunjie, Zaslaver, Olga, Chokshi, Chirayu, Shaikh, Muhammad Vaseem, Bakhshinyan, David, Burns, Ian, Chaudhry, Iqra, Nachmani, Omri, Mobilio, Daniel, Maich, William T., Mero, Patricia, Brown, Kevin R., Quaile, Andrew T., Venugopal, Chitra, Moffat, Jason, Montenegro-Burke, J Rafael, Singh, Sheila K.

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CD70 as an actionable immunotherapeutic target in recurrent glioblastoma and its microenvironment von Seyfrid, Mathieu, Maich, William Thomas, Shaikh, Vaseem Muhammad, Tatari, Nazanin, Upreti, Deepak, Piyasena, Deween, Subapanditha, Minomi, Savage, Neil, McKenna, Dillon, Mikolajewicz, Nicholas, Han, Hong, Chokshi, Chirayu, Kuhlmann, Laura, Khoo, Amanda, Salim, Sabra Khalid, Archibong-Bassey, Blessing, Gwynne, William, Brown, Kevin, Murtaza, Nadeem, Bakhshinyan, David, Vora, Parvez, Venugopal, Chitra, Moffat, Jason, Kislinger, Thomas, Singh, Sheila

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STEM-17. THE UROKINASE RECEPTOR AS A NOVEL IMMUNOTHERAPEUTIC TARGET IN BRAIN CANCERS von Maich, William, Shaikh, Muhammad Vaseem, Puri, Anish, Mobilio, Daniel, Ananda, Alisha, Venugopal, Chitra, Rossotti, Martin, Mikolajewicz, Nick, Chokshi, Chirayu, Salim, Sabra, Savage, Neil, Kislinger, Thomas, Henry, Kevin, Singh, Sheila

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Targeting axonal guidance dependencies in glioblastoma with ROBO1 CAR T cells von Chokshi, Chirayu R., Shaikh, Muhammad Vaseem, Brakel, Benjamin, Rossotti, Martin A., Tieu, David, Maich, William, Anand, Alisha, Chafe, Shawn C., Zhai, Kui, Suk, Yujin, Kieliszek, Agata M., Miletic, Petar, Mikolajewicz, Nicholas, Chen, David, McNicol, Jamie D., Chan, Katherine, Tong, Amy H. Y., Kuhlmann, Laura, Liu, Lina, Alizada, Zahra, Mobilio, Daniel, Tatari, Nazanin, Savage, Neil, Aghaei, Nikoo, Grewal, Shan, Puri, Anish, Subapanditha, Minomi, McKenna, Dillon, Ignatchenko, Vladimir, Salamoun, Joseph M., Kwiecien, Jacek M., Wipf, Peter, Sharlow, Elizabeth R., Provias, John P., Lu, Jian-Qiang, Lazo, John S., Kislinger, Thomas, Lu, Yu, Brown, Kevin R., Venugopal, Chitra, Henry, Kevin A., Moffat, Jason, Singh, Sheila K.

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Investigation of blood-brain barrier disruption in an animal model of mania induced by D-amphetamine von Géa, Luiza Paul, Wollenhaupt-Aguiar, Bianca, Watts, Devon, Maich, William, Kapczinski, Flavio, Sharma, Roohie, Mishra, Ram, Rosa, Adriane Ribeiro, Frey, Benicio N.

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Self-determination and inclusion: The role of Canadian principals in catalysing inclusive-positive practices von Harris MacCormack, Jeffrey William, Sider, Steve, Maich, Kimberly, Specht, Jacqueline Ann

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UPAR AS A NOVEL IMMUNOTHERAPEUTIC TARGET IN RECURRENT GLIOBLASTOMA von Maich, William, Shaikh, Vaseem, Puri, Anish, Anand, Alisha, Rosotti, Martin, Savage, Neil, Chokshi, Chirayu, Suk, Yujin, Gwynne, Will, Seyfrid, Mathieu, Venugopal, Chitra, Henry, Kevin, Singh, Sheila

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SYST-28 FUNCTIONAL MAPPING REVEALS WIDESPREAD REMODELLING AND A NOVEL TARGETABLE PTP4A2-ROBO1 SIGNALING AXIS AT GLIOBLASTOMA RECURRENCE von Chokshi, Chirayu, Shaikh, Vaseem, Tieu, David, Brakel, Benjamin, Brown, Kevin, chan, Katherine, rossotti, Martin, Maich, William, Venugopal, Chitra, Anand, Alisha, Lazo, John, Kislinger, Thomas, Lu, Jian, Provias, John, Henry, Kevin, Moffat, Jason, Singh, Sheila

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ROBO1 CAR-T CELL THERAPY FOR TREATMENT REFRACTORY BRAIN CANCER von Shaikh, Muhammad Vaseem, Chokshi, Chirayu R, Brakel, Benjamin, Anand, Alisha, Maich, William Thomas, Suk, Yujin, Kieliszek, Agata, Subapanditha, Minomi, Alizada, Zahra, Venugopal, Chitra, Rossotti, Martin A, Moffat, Jason, Henry, Kevin A, Kislinger, Thomas, Singh, Sheila K

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GENETIC SCREENING REVEALS DEPENDENCY ON FEN1 TO RESIST TEMOZOLOMIDE IN TREATMENT-RESISTANT GLIOBLASTOMA STEM CELLS von Brakel, Benjamin, Saleh, Ali, Saleh, Melissa, Miletic, Petar, Salim, Sabra, Maich, William, Brown, Kevin R, Tieu, David, Venugopal, Chitra, Moffat, Jason, Katyal, Sachin, Singh, Sheila K, Chokshi, Chirayu R

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Vehicle seat cushion assembly von BARR, WILLIAM, MAICH, LAWRENCE, BESSETTE, ANNE

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